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The map label for this gene is araH [H]

Identifier: 218548496

GI number: 218548496

Start: 1166323

End: 1167309

Strand: Direct

Name: araH [H]

Synonym: EFER_1125

Alternate gene names: 218548496

Gene position: 1166323-1167309 (Clockwise)

Preceding gene: 218548495

Following gene: 218548497

Centisome position: 25.42

GC content: 48.83

Gene sequence:

>987_bases
ATGTCATCAGTGACTACATCAGGTTCAGGCACGCCCAGGTCATCGTTTACTTTTAGCCGTATCTGGGATCAATACGGCAT
GTTGGTGGTCTTCGCGGTGCTGTTTATTGCCTGTGCCATTTTTGTGCCAAATTTTGCTACGTTTATCAATATGAAAGGAC
TGGGGTTAGCGATCTCCATGTCCGGCATGGTGGCGTGCGGTATGTTATTTTGCCTGGCTTCTGGCGACTTTGACCTTTCG
GTAGCCTCGGTGATTGCCTGTGCCGGAGTGACAACGGCAGTGGTCATCAATATGACCGAAAGCTTATGGTTAGGTGTGGC
GGCGGGATTATTGCTGGGCGTACTTTGTGGACTGGTTAATGGCTTCGTGATTGCACGATTGAAAATTAACGCCCTGATCA
CCACACTCGCAACTATGCAAATTGTACGTGGTCTGGCGTATATCATTTCTGACGGGAAAGCTGTAGGGATTGAGGATGAA
CGCTTCTTTACCCTCGGTTACGCCAACTGGTTTGGGCTACCTGCTCCTATCTGGTTAACGGTTGCCTGTTTAATTATTTT
TGGCTTGTTACTTAACAAAACTACGTTCGGCCGTAACACCTTGGCGATTGGCGGTAATGAAGAAGCTGCAAGGCTGGCGG
GTGTTCCGGTAGTGCGCACCAAAATCATTATTTTTGTTTTATCCGGGCTGGTATCAGCAGCCGCAGGGATCATTCTGGCG
TCGAGGATGACCAGTGGGCAACCGATGACGTCTATCGGCTATGAACTGATCGTGATTTCAGCGTGTGTACTGGGCGGTGT
CTCCCTAAAAGGTGGCATCGGAAAAATCTCATATGTGGTGGCCGGGATCTTAATTCTTGGCACGGTGGAAAACGCCATGA
ACCTGCTAAATATTTCGCCGTTTGCGCAGTATGTTGTTCGCGGCCTAATCCTGCTGGCAGCGGTGATTTTTGACCGTTAT
AAGCAAAAAGCGAAACGTACTCTTTAA

Upstream 100 bases:

>100_bases
TATCGGGGGAATTACTTCATGAGCAGGCAGATGAACGGCAGGCATTAAGCCTGGCGATGCCTAAAGTCAGCCAGGCAGTC
GCCTGAGTAAGGGGAATAAG

Downstream 100 bases:

>100_bases
GGTTTTTTTGCCCTGAGATAACTCTGAAAAGCCAGTCGCAGTCGCGGCTGGCTTCATCTTATGCCAATGGCGAGCCTCTT
CTCACTGTCTATACTTACAT

Product: L-arabinose transporter permease

Products: ADP; phosphate; arabinose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSSVTTSGSGTPRSSFTFSRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISMSGMVACGMLFCLASGDFDLS
VASVIACAGVTTAVVINMTESLWLGVAAGLLLGVLCGLVNGFVIARLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
RFFTLGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAAAGIILA
SRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRY
KQKAKRTL

Sequences:

>Translated_328_residues
MSSVTTSGSGTPRSSFTFSRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISMSGMVACGMLFCLASGDFDLS
VASVIACAGVTTAVVINMTESLWLGVAAGLLLGVLCGLVNGFVIARLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
RFFTLGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAAAGIILA
SRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRY
KQKAKRTL
>Mature_327_residues
SSVTTSGSGTPRSSFTFSRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISMSGMVACGMLFCLASGDFDLSV
ASVIACAGVTTAVVINMTESLWLGVAAGLLLGVLCGLVNGFVIARLKINALITTLATMQIVRGLAYIISDGKAVGIEDER
FFTLGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAAAGIILAS
RMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRYK
QKAKRTL

Specific function: Part of the binding-protein-dependent transport system for L-arabinose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1172

COG function: function code G; Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693152, Length=328, Percent_Identity=96.3414634146341, Blast_Score=600, Evalue=1e-173,
Organism=Escherichia coli, GI1790191, Length=331, Percent_Identity=35.3474320241692, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1790524, Length=320, Percent_Identity=29.375, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788896, Length=312, Percent_Identity=32.0512820512821, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789992, Length=135, Percent_Identity=44.4444444444444, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87082395, Length=272, Percent_Identity=32.7205882352941, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787793, Length=267, Percent_Identity=34.8314606741573, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693214, Length=242, Percent_Identity=37.1900826446281, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1787794, Length=276, Percent_Identity=29.3478260869565, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1788471, Length=327, Percent_Identity=30.5810397553517, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 34445; Mature: 34313

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVTTSGSGTPRSSFTFSRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISM
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEH
SGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINMTESLWLGVAAGLLLGVLCGLVN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFVIARLKINALITTLATMQIVRGLAYIISDGKAVGIEDERFFTLGYANWFGLPAPIWLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEECHHHCCCCHHHHHH
VACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAAAGIILA
HHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISP
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
FAQYVVRGLILLAAVIFDRYKQKAKRTL
HHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSVTTSGSGTPRSSFTFSRIWDQYGMLVVFAVLFIACAIFVPNFATFINMKGLGLAISM
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEEH
SGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINMTESLWLGVAAGLLLGVLCGLVN
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFVIARLKINALITTLATMQIVRGLAYIISDGKAVGIEDERFFTLGYANWFGLPAPIWLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEECHHHCCCCHHHHHH
VACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVVRTKIIIFVLSGLVSAAAGIILA
HHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKISYVVAGILILGTVENAMNLLNISP
HHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCH
FAQYVVRGLILLAAVIFDRYKQKAKRTL
HHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; arabinose [Periplasm]; H2O [C]

Specific reaction: ATP + arabinose [Periplasm] + H2O = ADP + phosphate + arabinose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2445996; 9097040; 9278503; 8045430 [H]