| Definition | Escherichia fergusonii ATCC 35469 chromosome, complete genome. |
|---|---|
| Accession | NC_011740 |
| Length | 4,588,711 |
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The map label for this gene is fabG [H]
Identifier: 218548183
GI number: 218548183
Start: 818271
End: 819053
Strand: Direct
Name: fabG [H]
Synonym: EFER_0800
Alternate gene names: 218548183
Gene position: 818271-819053 (Clockwise)
Preceding gene: 218548182
Following gene: 218548184
Centisome position: 17.83
GC content: 61.3
Gene sequence:
>783_bases ATGTGCTGCACAGCATCGGCTACATCCTGTAAGGAGTGCGTTATGACGCAAACCGTATTAGTCACCGGCGCGGCCGCCGG GCTGGGCAACGTCATCGCCATGCATCTGTTGTCGCAGGGGTATCAGGTGGTGCTCTCGGATGTGAGCCTTGCGCGCGCGC AACAGGCGGCGGACAAACTCGATAACGGCGCAGGTCACGTGCTGGCGCTGGAACTGGATATCCGCCAGCCGCAGGCGTTT GAGCAGGCGCTAAAGGCGATTGAAACCCGCTTCGGCAGCCTGGAGGTGCTGGTGAACAATGCCGCGCTGACCCTGGCGAC ATCGGTGATGGAGATTGACGTTGAAGAGTTTGACCGGGTGATCTCCACCAATCTACGCGGCACGTTCGTTGGCTGCCAGA CGATTGGGCGCTATTTCGCCAAAAAAGGCTACGGGCGAATTATCAATCTGGCGTCGCTGGCCGGACAGAACGGTGGCACG GCCTCCGGGGCGCACTATGCCGCGTCGAAAGGCGGCATCCTGACGCTGACCAAAATCTTCGCCCGCGAGCTGGGGAAATC CGGCGTAACGGTGAATGCCATCGCGCCGGGGCCGATGGATCTCCCGTCCGTTCACGCGCTGGTGCCGGAAGAGAAAATGG CCGGGCTGTTACAGATGATCCCGGTGGGTAAGTTGGGCGATGCCGAATTTGTCGCTCAGGCCGTGGCACTGCTGGCTTCA CCGCAGGCGGCGTTTGTCACCGGGGCGACCTGGGACATCAACGGCGGTCTGTTCATGCGTTAA
Upstream 100 bases:
>100_bases TACAGCCGTCACTACGCGGCGGATATCACCTGGCACCTGCAACCGCAGGGCGACAAGTTGCTGATTAAGCAAAAGGTGAT TCGTCTTATCAACAGCGACG
Downstream 100 bases:
>100_bases GGAGTCGCCATGCTGACACTGCATATTATTAAGCGCGAGCTTCAGGGGGATGTCGTCCTGCTGACGCTTGCCGACGCAAC CGGCGCTGAACTGCCTGCGT
Product: 3-oxoacyl-[acyl-carrier-protein] reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 260; Mature: 260
Protein sequence:
>260_residues MCCTASATSCKECVMTQTVLVTGAAAGLGNVIAMHLLSQGYQVVLSDVSLARAQQAADKLDNGAGHVLALELDIRQPQAF EQALKAIETRFGSLEVLVNNAALTLATSVMEIDVEEFDRVISTNLRGTFVGCQTIGRYFAKKGYGRIINLASLAGQNGGT ASGAHYAASKGGILTLTKIFARELGKSGVTVNAIAPGPMDLPSVHALVPEEKMAGLLQMIPVGKLGDAEFVAQAVALLAS PQAAFVTGATWDINGGLFMR
Sequences:
>Translated_260_residues MCCTASATSCKECVMTQTVLVTGAAAGLGNVIAMHLLSQGYQVVLSDVSLARAQQAADKLDNGAGHVLALELDIRQPQAF EQALKAIETRFGSLEVLVNNAALTLATSVMEIDVEEFDRVISTNLRGTFVGCQTIGRYFAKKGYGRIINLASLAGQNGGT ASGAHYAASKGGILTLTKIFARELGKSGVTVNAIAPGPMDLPSVHALVPEEKMAGLLQMIPVGKLGDAEFVAQAVALLAS PQAAFVTGATWDINGGLFMR >Mature_260_residues MCCTASATSCKECVMTQTVLVTGAAAGLGNVIAMHLLSQGYQVVLSDVSLARAQQAADKLDNGAGHVLALELDIRQPQAF EQALKAIETRFGSLEVLVNNAALTLATSVMEIDVEEFDRVISTNLRGTFVGCQTIGRYFAKKGYGRIINLASLAGQNGGT ASGAHYAASKGGILTLTKIFARELGKSGVTVNAIAPGPMDLPSVHALVPEEKMAGLLQMIPVGKLGDAEFVAQAVALLAS PQAAFVTGATWDINGGLFMR
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=33.7349397590361, Blast_Score=135, Evalue=5e-32, Organism=Homo sapiens, GI19923817, Length=248, Percent_Identity=30.241935483871, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI10190704, Length=255, Percent_Identity=28.6274509803922, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=31.5573770491803, Blast_Score=104, Evalue=1e-22, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=28.6885245901639, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI4758504, Length=268, Percent_Identity=31.3432835820896, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI66933014, Length=224, Percent_Identity=26.3392857142857, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI4504505, Length=213, Percent_Identity=32.8638497652582, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=25.5813953488372, Blast_Score=81, Evalue=8e-16, Organism=Homo sapiens, GI31542939, Length=210, Percent_Identity=30.952380952381, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI83715985, Length=268, Percent_Identity=29.4776119402985, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI59889578, Length=214, Percent_Identity=31.3084112149533, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503817, Length=189, Percent_Identity=26.984126984127, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4503301, Length=228, Percent_Identity=25.8771929824561, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=27.7227722772277, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI40254986, Length=187, Percent_Identity=25.668449197861, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI5031737, Length=241, Percent_Identity=26.1410788381743, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI225579078, Length=208, Percent_Identity=28.3653846153846, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI50726952, Length=206, Percent_Identity=25.7281553398058, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=39.4308943089431, Blast_Score=165, Evalue=3e-42, Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=29.9180327868852, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=29.6747967479675, Blast_Score=111, Evalue=6e-26, Organism=Escherichia coli, GI87082100, Length=248, Percent_Identity=31.0483870967742, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI2367175, Length=243, Percent_Identity=33.7448559670782, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=28.8617886178862, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=29.8755186721992, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1787905, Length=237, Percent_Identity=28.6919831223629, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1789057, Length=259, Percent_Identity=25.4826254826255, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1788459, Length=247, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=30.939226519337, Blast_Score=81, Evalue=7e-17, Organism=Escherichia coli, GI1786812, Length=250, Percent_Identity=24.8, Blast_Score=62, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=31.4285714285714, Blast_Score=122, Evalue=1e-28, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=32.1138211382114, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17536651, Length=246, Percent_Identity=28.0487804878049, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17536025, Length=246, Percent_Identity=25.609756097561, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=26.3565891472868, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17538182, Length=253, Percent_Identity=30.0395256916996, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17561272, Length=238, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561402, Length=257, Percent_Identity=28.4046692607004, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=25.609756097561, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=24.6153846153846, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17562910, Length=256, Percent_Identity=25.390625, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562990, Length=254, Percent_Identity=24.4094488188976, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI115534694, Length=244, Percent_Identity=26.2295081967213, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=26.8199233716475, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17562908, Length=256, Percent_Identity=25, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17508651, Length=253, Percent_Identity=29.6442687747036, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=25.1012145748988, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560150, Length=254, Percent_Identity=23.6220472440945, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=22.2222222222222, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=22.3938223938224, Blast_Score=71, Evalue=5e-13, Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=24.124513618677, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17531453, Length=255, Percent_Identity=25.8823529411765, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=23, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17508895, Length=190, Percent_Identity=25.2631578947368, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17558628, Length=189, Percent_Identity=27.5132275132275, Blast_Score=70, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71982365, Length=188, Percent_Identity=25.531914893617, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560220, Length=261, Percent_Identity=23.3716475095785, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=24.3386243386243, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17562904, Length=244, Percent_Identity=22.9508196721311, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17538480, Length=257, Percent_Identity=24.9027237354086, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI193203115, Length=182, Percent_Identity=25.2747252747253, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI193203117, Length=182, Percent_Identity=25.2747252747253, Blast_Score=65, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538486, Length=257, Percent_Identity=21.7898832684825, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17567345, Length=192, Percent_Identity=27.0833333333333, Blast_Score=64, Evalue=8e-11, Organism=Caenorhabditis elegans, GI72000259, Length=258, Percent_Identity=24.4186046511628, Blast_Score=64, Evalue=9e-11, Organism=Caenorhabditis elegans, GI17544670, Length=259, Percent_Identity=23.9382239382239, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=31.7708333333333, Blast_Score=81, Evalue=2e-16, Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=27.5303643724696, Blast_Score=80, Evalue=3e-16, Organism=Saccharomyces cerevisiae, GI6323882, Length=194, Percent_Identity=30.9278350515464, Blast_Score=76, Evalue=5e-15, Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=33.1983805668016, Blast_Score=134, Evalue=5e-32, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=32.7935222672065, Blast_Score=116, Evalue=2e-26, Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=31.1740890688259, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=28.8617886178862, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=30.3149606299213, Blast_Score=90, Evalue=1e-18, Organism=Drosophila melanogaster, GI24644339, Length=247, Percent_Identity=29.1497975708502, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI21357041, Length=247, Percent_Identity=28.7449392712551, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI21357673, Length=188, Percent_Identity=24.468085106383, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24643142, Length=246, Percent_Identity=28.8617886178862, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=30.5263157894737, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24644337, Length=195, Percent_Identity=29.7435897435897, Blast_Score=67, Evalue=8e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 27054; Mature: 27054
Theoretical pI: Translated: 6.51; Mature: 6.51
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 5.0 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 5.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MCCTASATSCKECVMTQTVLVTGAAAGLGNVIAMHLLSQGYQVVLSDVSLARAQQAADKL CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH DNGAGHVLALELDIRQPQAFEQALKAIETRFGSLEVLVNNAALTLATSVMEIDVEEFDRV CCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCHHHHHHH ISTNLRGTFVGCQTIGRYFAKKGYGRIINLASLAGQNGGTASGAHYAASKGGILTLTKIF HHCCCCEEEEHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHH ARELGKSGVTVNAIAPGPMDLPSVHALVPEEKMAGLLQMIPVGKLGDAEFVAQAVALLAS HHHHCCCCCEEEEECCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC PQAAFVTGATWDINGGLFMR CCHHEEECCEEECCCCEECC >Mature Secondary Structure MCCTASATSCKECVMTQTVLVTGAAAGLGNVIAMHLLSQGYQVVLSDVSLARAQQAADKL CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH DNGAGHVLALELDIRQPQAFEQALKAIETRFGSLEVLVNNAALTLATSVMEIDVEEFDRV CCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHCCHHHHHHH ISTNLRGTFVGCQTIGRYFAKKGYGRIINLASLAGQNGGTASGAHYAASKGGILTLTKIF HHCCCCEEEEHHHHHHHHHHHCCCCCEEEHHHHCCCCCCCCCCCCCCCCCCCEEHHHHHH ARELGKSGVTVNAIAPGPMDLPSVHALVPEEKMAGLLQMIPVGKLGDAEFVAQAVALLAS HHHHCCCCCEEEEECCCCCCCCCHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCC PQAAFVTGATWDINGGLFMR CCHHEEECCEEECCCCEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10952301 [H]