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The map label for this gene is cdaR [H]

Identifier: 218547618

GI number: 218547618

Start: 204190

End: 205347

Strand: Direct

Name: cdaR [H]

Synonym: EFER_0185

Alternate gene names: 218547618

Gene position: 204190-205347 (Clockwise)

Preceding gene: 218547617

Following gene: 218547624

Centisome position: 4.45

GC content: 50.69

Gene sequence:

>1158_bases
ATGGCTGGATGGCATCTTGATACCAAAATGGCTCAGGATATCGTGGCGCGGACCATGCGCATTATCGATACCAATATCAA
CGTAATGGATGCCCGCGGGCGCATTATCGGCAGCGGCGATCGTGAGCGTATTGGTGAATTGCATGAAGGCGCATTGTTGG
TGCTTGCACAAGGACGCGTTGTGGATATTGATGACGCCGTGGCGCGGCATTTGCACGGCGTGCGACAAGGAATAAATCTA
CCACTGCGGCTGGAAGGTGAGATTGTTGGCGTCATTGGTCTGACGGGCGAACCAGAGCATTTACGAAAATATGGTGAGCT
GGTCTGTATGACTTCCGAAATGATGCTTGAGCAGTCACGATTGATGCATCTGCTGGCCCAGGATAGTCGCCTGCGGGAAG
AGTTGGTGATGAATCTGATTCAGGCAGAAGAAAATACACCAGCGTTAACTGAGTGGGCGCAGCGGCTGGGTATCGATCTT
AATCAGCCACGTGTGGTCGCGGTTGTGGAGGTGGATAGCGGGCAGCTCGGTGTAGATAGTGCGATGGCTGAGTTGCAGCA
ATTACAAAACGCCCTTACCACCCCGGAACGAAATAATCTGATTGCGATTGTCTCTCTGACGGAAATGGTAGTACTCAAAC
CGGCCCTAAACCCGTTTGGGCGCTGGGATGCTGAAGATCATCGCAAGCGTGTTGAACAATTGATTTCACGTATGAAAGAG
AATGGACAGCTACGTTTTCGCGTCGCGCTGGGCAACTATTTCACCGGACCTGGCAGCATCGCACGTTCTTATCGTACGGC
CCGTACGACGATGATGGTCGGAAAACAACGGATGCCGGAAAGCCGCAGTTATTTTTATCAAGATTTGATGTTGCCAGTGC
TGCTGGATAGCTTGCGTGGTGGTTGGCAGGCAAATGAACTTGCTCGTCCTTTGGCAAGACTTAAAGCGATGGATAATAAC
GGTCTGTTGCGCCGCACACTGAACGCGTGGTTTCGCCATAATGTTCAGCCGTTGGCAACCTCAAAAGCATTATTTATCCA
TCGTAATACTCTGGAGTACCGGCTTAATCGCATATCGGAACTCACTGGCTTAGATCTGGGGAATTTTGATGACAGGTTAT
TGTTGTATGTGGCGTTACAACTGGATGAGCAGCGATAG

Upstream 100 bases:

>100_bases
CCCTCCACAACTCCATATTTCTTCCTTCTCCTTTGTGCGATTGCACAATGTCGGTATTTAAACATCTCCTTATGCTAGAA
CCCTGCACAATGGAGGGCTT

Downstream 100 bases:

>100_bases
GGTAAAAAGAGTAAATGCCGGGAAATATGCTCGTCTTACTTCAAGTTGCATGTACGGTGACTCGAATTATTCAGCGTATA
CTTTACCCGGCTGGCAGAAT

Product: carbohydrate diacid transcriptional activator CdaR

Products: NA

Alternate protein names: Sugar diacid regulator [H]

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLAQGRVVDIDDAVARHLHGVRQGINL
PLRLEGEIVGVIGLTGEPEHLRKYGELVCMTSEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
NQPRVVAVVEVDSGQLGVDSAMAELQQLQNALTTPERNNLIAIVSLTEMVVLKPALNPFGRWDAEDHRKRVEQLISRMKE
NGQLRFRVALGNYFTGPGSIARSYRTARTTMMVGKQRMPESRSYFYQDLMLPVLLDSLRGGWQANELARPLARLKAMDNN
GLLRRTLNAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEQR

Sequences:

>Translated_385_residues
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLAQGRVVDIDDAVARHLHGVRQGINL
PLRLEGEIVGVIGLTGEPEHLRKYGELVCMTSEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
NQPRVVAVVEVDSGQLGVDSAMAELQQLQNALTTPERNNLIAIVSLTEMVVLKPALNPFGRWDAEDHRKRVEQLISRMKE
NGQLRFRVALGNYFTGPGSIARSYRTARTTMMVGKQRMPESRSYFYQDLMLPVLLDSLRGGWQANELARPLARLKAMDNN
GLLRRTLNAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEQR
>Mature_384_residues
AGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLAQGRVVDIDDAVARHLHGVRQGINLP
LRLEGEIVGVIGLTGEPEHLRKYGELVCMTSEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDLN
QPRVVAVVEVDSGQLGVDSAMAELQQLQNALTTPERNNLIAIVSLTEMVVLKPALNPFGRWDAEDHRKRVEQLISRMKEN
GQLRFRVALGNYFTGPGSIARSYRTARTTMMVGKQRMPESRSYFYQDLMLPVLLDSLRGGWQANELARPLARLKAMDNNG
LLRRTLNAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEQR

Specific function: Seems to regulate the expression of the operons for the enzymes involved in D-galactarate, D-glucarate and D-glycerate utilization [H]

COG id: COG3835

COG function: function code KT; Sugar diacid utilization regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdaR family [H]

Homologues:

Organism=Escherichia coli, GI87081694, Length=385, Percent_Identity=95.8441558441558, Blast_Score=753, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008599 [H]

Pfam domain/function: PF05651 Diacid_rec [H]

EC number: NA

Molecular weight: Translated: 43640; Mature: 43509

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLAQGRV
CCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHCCCEEEEEECCCE
VDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPEHLRKYGELVCMTSEMMLEQSR
EECHHHHHHHHHHHHHCCCCCEEECCEEEEEEECCCCHHHHHHHHHEEEEHHHHHHHHHH
LMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDLNQPRVVAVVEVDSGQLGVDS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHH
AMAELQQLQNALTTPERNNLIAIVSLTEMVVLKPALNPFGRWDAEDHRKRVEQLISRMKE
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
NGQLRFRVALGNYFTGPGSIARSYRTARTTMMVGKQRMPESRSYFYQDLMLPVLLDSLRG
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
GWQANELARPLARLKAMDNNGLLRRTLNAWFRHNVQPLATSKALFIHRNTLEYRLNRISE
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHH
LTGLDLGNFDDRLLLYVALQLDEQR
HHCCCCCCCCCCEEEEEEEECCCCC
>Mature Secondary Structure 
AGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLAQGRV
CCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEECCCCHHHHHHHCCCEEEEEECCCE
VDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPEHLRKYGELVCMTSEMMLEQSR
EECHHHHHHHHHHHHHCCCCCEEECCEEEEEEECCCCHHHHHHHHHEEEEHHHHHHHHHH
LMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDLNQPRVVAVVEVDSGQLGVDS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHH
AMAELQQLQNALTTPERNNLIAIVSLTEMVVLKPALNPFGRWDAEDHRKRVEQLISRMKE
HHHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
NGQLRFRVALGNYFTGPGSIARSYRTARTTMMVGKQRMPESRSYFYQDLMLPVLLDSLRG
CCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCC
GWQANELARPLARLKAMDNNGLLRRTLNAWFRHNVQPLATSKALFIHRNTLEYRLNRISE
CCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHH
LTGLDLGNFDDRLLLYVALQLDEQR
HHCCCCCCCCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10762278 [H]