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The map label for this gene is secM [H]

Identifier: 218547554

GI number: 218547554

Start: 129625

End: 130182

Strand: Direct

Name: secM [H]

Synonym: EFER_0119

Alternate gene names: 218547554

Gene position: 129625-130182 (Clockwise)

Preceding gene: 218547553

Following gene: 218547555

Centisome position: 2.82

GC content: 52.87

Gene sequence:

>558_bases
ATGATAAGATTTGTTTGTAAAAAGTGTGCATATGATCAGGATGGCAATGACGTGAGTGGAATACTGACGCGCTGGCGACA
GTTAGGTAGACGCTACTTCTGGCCGCATCTCTTGTTAGGGATGGTCGCGGCGAGTTTAGGGTTGCCTGCGCTCAGCAATG
CTGCCGAGCCTAACGCACCTGCGAAAGCCACCTCCAGTAATCATGAACCTTCTGCGAAGGTTAACTTTAGCCAGCTTGCT
TTGCTTGAGGCTAACACTCGTCGGCCTAATTATTCCGTTGATTACTGGCATCAGCACGCAATTCGTACCGTTATTCGTCA
TCTCTCTTTTGCCATGGCACCGCAAGTCTTGCCTGTTGCAGAAGAGTCGTCCCCGCTGCAGGCTCAGCACCTTGCTCTGC
TGAATACGCTCAGTGCGATGCTGACGCAAGAAGGTACACCTGCCACCATTGTGCACCGCGTGGACTATGCCCATTTCTCT
CCTCTGGCTGCATTTAGCACATCCGTCTGGATTAGCCAGGCGCAGGGTATCCGCGCCGGCCCTCAACGCCTTAGCTAA

Upstream 100 bases:

>100_bases
ATTTTATCTATTGCAGCAAAACAGTGTTGTGCGAACGCTGCTTTATTAATCACTTTTACCCCTGAGTACTCGTCATTACT
GCTGTGGAATACGGGCTTTA

Downstream 100 bases:

>100_bases
AAATATAAAACCATTAATTCCTTGTATTGACTCCGCTGAGCGGGGCGTTTGAGATTTTATTATGCTTATCAAATTATTAA
CAAAAGTATTCGGTAGCCGT

Product: SecA regulator SecM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MIRFVCKKCAYDQDGNDVSGILTRWRQLGRRYFWPHLLLGMVAASLGLPALSNAAEPNAPAKATSSNHEPSAKVNFSQLA
LLEANTRRPNYSVDYWHQHAIRTVIRHLSFAMAPQVLPVAEESSPLQAQHLALLNTLSAMLTQEGTPATIVHRVDYAHFS
PLAAFSTSVWISQAQGIRAGPQRLS

Sequences:

>Translated_185_residues
MIRFVCKKCAYDQDGNDVSGILTRWRQLGRRYFWPHLLLGMVAASLGLPALSNAAEPNAPAKATSSNHEPSAKVNFSQLA
LLEANTRRPNYSVDYWHQHAIRTVIRHLSFAMAPQVLPVAEESSPLQAQHLALLNTLSAMLTQEGTPATIVHRVDYAHFS
PLAAFSTSVWISQAQGIRAGPQRLS
>Mature_185_residues
MIRFVCKKCAYDQDGNDVSGILTRWRQLGRRYFWPHLLLGMVAASLGLPALSNAAEPNAPAKATSSNHEPSAKVNFSQLA
LLEANTRRPNYSVDYWHQHAIRTVIRHLSFAMAPQVLPVAEESSPLQAQHLALLNTLSAMLTQEGTPATIVHRVDYAHFS
PLAAFSTSVWISQAQGIRAGPQRLS

Specific function: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm, cytosol. Periplasm (By similarity). Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secM family [H]

Homologues:

Organism=Escherichia coli, GI87081686, Length=170, Percent_Identity=86.4705882352941, Blast_Score=301, Evalue=2e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009502
- ProDom:   PD089227 [H]

Pfam domain/function: PF06558 SecM [H]

EC number: NA

Molecular weight: Translated: 20398; Mature: 20398

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFVCKKCAYDQDGNDVSGILTRWRQLGRRYFWPHLLLGMVAASLGLPALSNAAEPNAP
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCC
AKATSSNHEPSAKVNFSQLALLEANTRRPNYSVDYWHQHAIRTVIRHLSFAMAPQVLPVA
CCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EESSPLQAQHLALLNTLSAMLTQEGTPATIVHRVDYAHFSPLAAFSTSVWISQAQGIRAG
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCHHHHHHHHHHHHHCCCCCCC
PQRLS
CCCCC
>Mature Secondary Structure
MIRFVCKKCAYDQDGNDVSGILTRWRQLGRRYFWPHLLLGMVAASLGLPALSNAAEPNAP
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCC
AKATSSNHEPSAKVNFSQLALLEANTRRPNYSVDYWHQHAIRTVIRHLSFAMAPQVLPVA
CCCCCCCCCCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
EESSPLQAQHLALLNTLSAMLTQEGTPATIVHRVDYAHFSPLAAFSTSVWISQAQGIRAG
CCCCCHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHCHHHHHHHHHHHHHCCCCCCC
PQRLS
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA