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The map label for this gene is aroE [H]

Identifier: 218547527

GI number: 218547527

Start: 97670

End: 98533

Strand: Reverse

Name: aroE [H]

Synonym: EFER_0091

Alternate gene names: 218547527

Gene position: 98533-97670 (Counterclockwise)

Preceding gene: 218547528

Following gene: 218547526

Centisome position: 2.15

GC content: 48.73

Gene sequence:

>864_bases
ATGGCAGAACGTATTACCGGGCATACTGAACTGATTGGGCTTATTGCGACACCTATTCGTCATAGCATGTCTCCAACAAT
GCACAATGAAGCCTTTGCACATCTGGGGCTGGACTATGTTTACCTAGCTTTTGAAGTCGATAACCAGGAACTGAAAGATG
TTGTTCAGGGATTCCGGGCCCTAAAACTGCGCGGCTTTAATGTTTCAATGCCAAATAAAACCGAGATTTGTCAGTATCTG
GACAATCTCTCTCCGGCTGCGCAACTGGTTGGTGCGGTCAACACTGTCGTTAACGATGACGGCATATTAACCGGCCACAT
CACCGATGGCACGGGCTATATGCGTGCACTGAAAGAAGCCAATATTGATGTTATCGGCAAAAAAATGACTGTCCTGGGTG
CAGGAGGAGCTGCCACCGCAATTTGCGTACAGGCAGCACTGGACGGCGTGAAAGAAATTTCTATCTTCAACAAACGGGAT
AAATTTTTCCCGAATGCCGAGCAAACTGTGGCGAAGATCCGCAACAACACCGACTGCGAGATCCATCTGTTTGATCTCGA
CGATCATGACAAGTTGCGTGCAGAGATTGACTGCAGTGTGCTGCTCACCAATGCCACTGGCGTAGGTATGAAGCCGTTCG
AAGGGCAAATGTTGCTGCCCGATGCCAGTTTCCTGCGCCCGGATCTGATCGTCTCTGATGTGGTGTACAACCCACGCAAA
ACCCATCTGTTGGAAGTCGCAGAGAACAGCGGTTGTCGCACTATTAACGGCCTGGGAATGATGCTCTGGCAAGGTGCTGC
AGCTTTTGAAATCTGGACGGGTAAAGAAATGCCCGTTGATTATATTAAAAGCATTCTGTTCTAA

Upstream 100 bases:

>100_bases
TATTGATGGTGTGCGGGAAGGCCGCAGCGTACTGGATACCCTGGAAGATATGGGTGCCCTGGGAAAAGAATTTCATTTCT
AACAACTTGAGGACGTTATC

Downstream 100 bases:

>100_bases
GGTCGGCGTAATGAAAAATAAATACGTCCCAACTGCGGCGGGGCTTTATCTCAACTATATGCTTCACGGCATGGGGGTGC
TGTTAATCACCCTCAACATG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MAERITGHTELIGLIATPIRHSMSPTMHNEAFAHLGLDYVYLAFEVDNQELKDVVQGFRALKLRGFNVSMPNKTEICQYL
DNLSPAAQLVGAVNTVVNDDGILTGHITDGTGYMRALKEANIDVIGKKMTVLGAGGAATAICVQAALDGVKEISIFNKRD
KFFPNAEQTVAKIRNNTDCEIHLFDLDDHDKLRAEIDCSVLLTNATGVGMKPFEGQMLLPDASFLRPDLIVSDVVYNPRK
THLLEVAENSGCRTINGLGMMLWQGAAAFEIWTGKEMPVDYIKSILF

Sequences:

>Translated_287_residues
MAERITGHTELIGLIATPIRHSMSPTMHNEAFAHLGLDYVYLAFEVDNQELKDVVQGFRALKLRGFNVSMPNKTEICQYL
DNLSPAAQLVGAVNTVVNDDGILTGHITDGTGYMRALKEANIDVIGKKMTVLGAGGAATAICVQAALDGVKEISIFNKRD
KFFPNAEQTVAKIRNNTDCEIHLFDLDDHDKLRAEIDCSVLLTNATGVGMKPFEGQMLLPDASFLRPDLIVSDVVYNPRK
THLLEVAENSGCRTINGLGMMLWQGAAAFEIWTGKEMPVDYIKSILF
>Mature_286_residues
AERITGHTELIGLIATPIRHSMSPTMHNEAFAHLGLDYVYLAFEVDNQELKDVVQGFRALKLRGFNVSMPNKTEICQYLD
NLSPAAQLVGAVNTVVNDDGILTGHITDGTGYMRALKEANIDVIGKKMTVLGAGGAATAICVQAALDGVKEISIFNKRDK
FFPNAEQTVAKIRNNTDCEIHLFDLDDHDKLRAEIDCSVLLTNATGVGMKPFEGQMLLPDASFLRPDLIVSDVVYNPRKT
HLLEVAENSGCRTINGLGMMLWQGAAAFEIWTGKEMPVDYIKSILF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=282, Percent_Identity=51.4184397163121, Blast_Score=322, Evalue=2e-89,
Organism=Escherichia coli, GI1789675, Length=268, Percent_Identity=29.4776119402985, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320332, Length=286, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 31500; Mature: 31368

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERITGHTELIGLIATPIRHSMSPTMHNEAFAHLGLDYVYLAFEVDNQELKDVVQGFRA
CCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHH
LKLRGFNVSMPNKTEICQYLDNLSPAAQLVGAVNTVVNDDGILTGHITDGTGYMRALKEA
HEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHEECCCCEEEEEEECCHHHHHHHHHC
NIDVIGKKMTVLGAGGAATAICVQAALDGVKEISIFNKRDKFFPNAEQTVAKIRNNTDCE
CCEEECCEEEEEECCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCE
IHLFDLDDHDKLRAEIDCSVLLTNATGVGMKPFEGQMLLPDASFLRPDLIVSDVVYNPRK
EEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEECCCHHHCCCCHHHHHHHCCCCH
THLLEVAENSGCRTINGLGMMLWQGAAAFEIWTGKEMPVDYIKSILF
HEEEEEECCCCCEEECCCHHEECCCCCEEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure 
AERITGHTELIGLIATPIRHSMSPTMHNEAFAHLGLDYVYLAFEVDNQELKDVVQGFRA
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHH
LKLRGFNVSMPNKTEICQYLDNLSPAAQLVGAVNTVVNDDGILTGHITDGTGYMRALKEA
HEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHEECCCCEEEEEEECCHHHHHHHHHC
NIDVIGKKMTVLGAGGAATAICVQAALDGVKEISIFNKRDKFFPNAEQTVAKIRNNTDCE
CCEEECCEEEEEECCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCE
IHLFDLDDHDKLRAEIDCSVLLTNATGVGMKPFEGQMLLPDASFLRPDLIVSDVVYNPRK
EEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCCEECCCHHHCCCCHHHHHHHCCCCH
THLLEVAENSGCRTINGLGMMLWQGAAAFEIWTGKEMPVDYIKSILF
HEEEEEECCCCCEEECCCHHEECCCCCEEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]