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The map label for this gene is yybE [H]

Identifier: 218547524

GI number: 218547524

Start: 94730

End: 95626

Strand: Direct

Name: yybE [H]

Synonym: EFER_0088

Alternate gene names: 218547524

Gene position: 94730-95626 (Clockwise)

Preceding gene: 218547523

Following gene: 218547534

Centisome position: 2.06

GC content: 39.46

Gene sequence:

>897_bases
ATGAATCTAAAGCAACTTTATTATTTTAAGCGTCTTGCTGAAACAGAACATTACACTGAAGCAGCATCCGCACTTTGTAT
TACTCAACCCGCCCTAAGCCACGCAATCTCTGAACTGGAGAAAGAGTTAGGTGTGGCACTCTTTGCCCGCCGTGGGCGTA
ACATTCAGATCACGCCAAACGGTAAACGTTTTTTACCCTATGTTGAAGATGCTCTGACGTCATTAGAGAATGGTCGTATG
ACGTTACAAAAAAGTTGCGATAAAAACAAAGAAAATATTCGTATTGCCTTTATTTATACCATGGGGGAATATGTTGTCCC
ACAGTTAATCAATAAATTCTCATTATCACCTGCATATTCAGATGTGACATTTTCTTTTACCCAGGGAACATCGTTAACGT
TATTACAGGATTTAAAAGCAGGAAAAACAGATTTAGCAATATGTTCTTATATTGCCGATGAGCCTGATATTAATTTTATT
CCTGTTATTCAACAGGAATTGGTTGTGGTTACCGCCAGGGAACACCCACTCGCCAGTTTATATAAAAATGAGGTCGATTT
AGGCGAGACGATCCATTATCCCTATGTATATTTTTCTGAAAACAGCGGCTTACGTCCATTTATTGATAACGTATTTATGC
AGCAAAAACTGGTGCCAGATATTGCCTGCTATGTGGAAGAAGATACAGCAATGGCGGGTCTGGTGAGTATCAATTACGGT
ATTGCTATTATGCCAAGAATTACTGCTCTCTCTTATTACCCTGTACATATTCTGAACATTAAAAATGCGATTCCTCCACG
TTATATCTACCTGGCGACGATGAAAGATCGTGTGCTCTCCCCGGCATTACAGACATTTAAAGATGTCATCATCAACGATT
GCCAGAGTTTTCGGTAA

Upstream 100 bases:

>100_bases
TGATATGACTCCAGAAAATGACGTTTAGTCCGCAGCAATATTAAACGCTATGGTATATTGGCTACAGTGATTTTATTCTT
ATATTATACGGTCAAAAATA

Downstream 100 bases:

>100_bases
TAATGCGCCCGGCATTAAATTCCGGGCGCAAAGCCATCAGGAAAGAATATCCATTACTTCACGCAACTGAGCAATGGCGA
TCTGCCCAGGCGCTGAAGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNLKQLYYFKRLAETEHYTEAASALCITQPALSHAISELEKELGVALFARRGRNIQITPNGKRFLPYVEDALTSLENGRM
TLQKSCDKNKENIRIAFIYTMGEYVVPQLINKFSLSPAYSDVTFSFTQGTSLTLLQDLKAGKTDLAICSYIADEPDINFI
PVIQQELVVVTAREHPLASLYKNEVDLGETIHYPYVYFSENSGLRPFIDNVFMQQKLVPDIACYVEEDTAMAGLVSINYG
IAIMPRITALSYYPVHILNIKNAIPPRYIYLATMKDRVLSPALQTFKDVIINDCQSFR

Sequences:

>Translated_298_residues
MNLKQLYYFKRLAETEHYTEAASALCITQPALSHAISELEKELGVALFARRGRNIQITPNGKRFLPYVEDALTSLENGRM
TLQKSCDKNKENIRIAFIYTMGEYVVPQLINKFSLSPAYSDVTFSFTQGTSLTLLQDLKAGKTDLAICSYIADEPDINFI
PVIQQELVVVTAREHPLASLYKNEVDLGETIHYPYVYFSENSGLRPFIDNVFMQQKLVPDIACYVEEDTAMAGLVSINYG
IAIMPRITALSYYPVHILNIKNAIPPRYIYLATMKDRVLSPALQTFKDVIINDCQSFR
>Mature_298_residues
MNLKQLYYFKRLAETEHYTEAASALCITQPALSHAISELEKELGVALFARRGRNIQITPNGKRFLPYVEDALTSLENGRM
TLQKSCDKNKENIRIAFIYTMGEYVVPQLINKFSLSPAYSDVTFSFTQGTSLTLLQDLKAGKTDLAICSYIADEPDINFI
PVIQQELVVVTAREHPLASLYKNEVDLGETIHYPYVYFSENSGLRPFIDNVFMQQKLVPDIACYVEEDTAMAGLVSINYG
IAIMPRITALSYYPVHILNIKNAIPPRYIYLATMKDRVLSPALQTFKDVIINDCQSFR

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=293, Percent_Identity=27.3037542662116, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI157672245, Length=291, Percent_Identity=26.1168384879725, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787879, Length=301, Percent_Identity=25.2491694352159, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788296, Length=247, Percent_Identity=25.9109311740891, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788887, Length=296, Percent_Identity=24.3243243243243, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787530, Length=258, Percent_Identity=24.031007751938, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788481, Length=292, Percent_Identity=25, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1787806, Length=256, Percent_Identity=26.171875, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790208, Length=299, Percent_Identity=23.0769230769231, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1788748, Length=296, Percent_Identity=24.6621621621622, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790399, Length=179, Percent_Identity=25.6983240223464, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87081904, Length=241, Percent_Identity=23.2365145228216, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790262, Length=255, Percent_Identity=26.2745098039216, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082132, Length=249, Percent_Identity=22.4899598393574, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1790783, Length=245, Percent_Identity=23.6734693877551, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787601, Length=303, Percent_Identity=20.4620462046205, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994962, Length=150, Percent_Identity=27.3333333333333, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789204, Length=253, Percent_Identity=23.3201581027668, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1788297, Length=252, Percent_Identity=20.6349206349206, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33763; Mature: 33763

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKQLYYFKRLAETEHYTEAASALCITQPALSHAISELEKELGVALFARRGRNIQITPN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
GKRFLPYVEDALTSLENGRMTLQKSCDKNKENIRIAFIYTMGEYVVPQLINKFSLSPAYS
CCEECHHHHHHHHHHCCCCEEEHHHCCCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCCC
DVTFSFTQGTSLTLLQDLKAGKTDLAICSYIADEPDINFIPVIQQELVVVTAREHPLASL
CEEEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCHHHH
YKNEVDLGETIHYPYVYFSENSGLRPFIDNVFMQQKLVPDIACYVEEDTAMAGLVSINYG
HHCCCCCCCEEECCEEEECCCCCCCHHHHHHHHHHHHCCHHEEEEECCCHHEEEEEECCC
IAIMPRITALSYYPVHILNIKNAIPPRYIYLATMKDRVLSPALQTFKDVIINDCQSFR
EEEEEHHHEEEECCEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLKQLYYFKRLAETEHYTEAASALCITQPALSHAISELEKELGVALFARRGRNIQITPN
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
GKRFLPYVEDALTSLENGRMTLQKSCDKNKENIRIAFIYTMGEYVVPQLINKFSLSPAYS
CCEECHHHHHHHHHHCCCCEEEHHHCCCCCCCEEEEEEEECHHHHHHHHHHHHCCCCCCC
DVTFSFTQGTSLTLLQDLKAGKTDLAICSYIADEPDINFIPVIQQELVVVTAREHPLASL
CEEEEEECCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEECCCCEEEEEECCCCHHHH
YKNEVDLGETIHYPYVYFSENSGLRPFIDNVFMQQKLVPDIACYVEEDTAMAGLVSINYG
HHCCCCCCCEEECCEEEECCCCCCCHHHHHHHHHHHHCCHHEEEEECCCHHEEEEEECCC
IAIMPRITALSYYPVHILNIKNAIPPRYIYLATMKDRVLSPALQTFKDVIINDCQSFR
EEEEEHHHEEEECCEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]