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The map label for this gene is citC [H]

Identifier: 218547471

GI number: 218547471

Start: 32272

End: 33282

Strand: Direct

Name: citC [H]

Synonym: EFER_0032

Alternate gene names: 218547471

Gene position: 32272-33282 (Clockwise)

Preceding gene: 218547464

Following gene: 218547472

Centisome position: 0.7

GC content: 48.86

Gene sequence:

>1011_bases
GTGAATATCATCTTTAAACAGTGTATTCCACAACGGGATGCCAGGAACAGGGCTCGGCTGGTTGAGTTTCTTAGCGAGTC
AGGGCTGACGTTGGAAGCCGATTGCGAAGTCATGGTACTGGCAGAGCAACGTGGGCGCCTGGTCGGCTGCGGCGCTATTG
CGGGTAATGTCATTAAAGATATCGCCATCGACCCTACTGCGCGTGGTGACGGCCTGAGTCTGAAATTGCTCACTGAACTA
CTTATACTGGCTTGTGAGATGGGACGTAACGATCTTTTTCTGTTTACCAAACCGGAAAACGTCGTGCTTTTTTCTGGCGC
TGGTTTTTTCCCTATTGCGCAGACAGAGCACGTTGTTCTGATGGAAAATAGCCGTGAACGGCTGACACGTTATTGCCGAC
AACTTGCATTATATCGCCAGCCAGGAAATAAAATTGGCGCAATTGTAATGAATGCCAATCCATTTACCCTCGGGCATCGT
TATCTCGTAGAGCAGGCATTAAAACAGTGCGACTGGTTGCATATATTTGTAGTTCAGGAAGATGCCTCTTTTTTCAGTTA
TCTCGATCGCTGGAAATTAATTGAACAGGGTATTTTGGGAATGGATCGTGTGACACTGCATCCAGGATCGTCATATATCA
TTTCTCGAGCCACTTTCCCGGGTTATTTCCTCAAGGATAAAGGCGTGATAGATGAAAGCCACAGCCAAATCGATTTACAA
CTCTTTCGTGATCACCTCGCGCCCGCATTAGGCATCACACACCGCTTTGTGGGTACAGAACCAAACTGCCAGCTGACCCG
CGCCTATAACCAGAAAATGAAAACGCTGCTGGCACCCGCCATTGAAGTGGTGGAACTACCCAGAACAGAAAAAGAAGGCG
CTGCAATTTCAGCTTCTCGCGTGCGCAAACTTTACAACGAACGAAACTGGCAGGCACTGGCGCCGCTGGTTCCTTCTTCA
ACACTCGCTTTTTTGACGCGTCTGGCGGCCGGTAATACGGAAACGGCATGA

Upstream 100 bases:

>100_bases
AAGCCAGATAAAAATACCCTGCAGAATGTGAGCAGAATAAAAGAATGATCCCCCCAGCAATGGCGAAATACGCCTGTATA
TTTTCTACAGGTGGGAAATA

Downstream 100 bases:

>100_bases
CATTTTCTTCGTGAATAAGGAAAGAACAGATGGAAATTATTAAAGACGCCCTGGCCGGCACGCTGGAATCCAGCGATGTC
ATGGTCAGAATTGGCCCTTG

Product: citrate lyase synthetase

Products: NA

Alternate protein names: Acetate:SH-citrate lyase ligase; Citrate lyase synthetase [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNIIFKQCIPQRDARNRARLVEFLSESGLTLEADCEVMVLAEQRGRLVGCGAIAGNVIKDIAIDPTARGDGLSLKLLTEL
LILACEMGRNDLFLFTKPENVVLFSGAGFFPIAQTEHVVLMENSRERLTRYCRQLALYRQPGNKIGAIVMNANPFTLGHR
YLVEQALKQCDWLHIFVVQEDASFFSYLDRWKLIEQGILGMDRVTLHPGSSYIISRATFPGYFLKDKGVIDESHSQIDLQ
LFRDHLAPALGITHRFVGTEPNCQLTRAYNQKMKTLLAPAIEVVELPRTEKEGAAISASRVRKLYNERNWQALAPLVPSS
TLAFLTRLAAGNTETA

Sequences:

>Translated_336_residues
MNIIFKQCIPQRDARNRARLVEFLSESGLTLEADCEVMVLAEQRGRLVGCGAIAGNVIKDIAIDPTARGDGLSLKLLTEL
LILACEMGRNDLFLFTKPENVVLFSGAGFFPIAQTEHVVLMENSRERLTRYCRQLALYRQPGNKIGAIVMNANPFTLGHR
YLVEQALKQCDWLHIFVVQEDASFFSYLDRWKLIEQGILGMDRVTLHPGSSYIISRATFPGYFLKDKGVIDESHSQIDLQ
LFRDHLAPALGITHRFVGTEPNCQLTRAYNQKMKTLLAPAIEVVELPRTEKEGAAISASRVRKLYNERNWQALAPLVPSS
TLAFLTRLAAGNTETA
>Mature_336_residues
MNIIFKQCIPQRDARNRARLVEFLSESGLTLEADCEVMVLAEQRGRLVGCGAIAGNVIKDIAIDPTARGDGLSLKLLTEL
LILACEMGRNDLFLFTKPENVVLFSGAGFFPIAQTEHVVLMENSRERLTRYCRQLALYRQPGNKIGAIVMNANPFTLGHR
YLVEQALKQCDWLHIFVVQEDASFFSYLDRWKLIEQGILGMDRVTLHPGSSYIISRATFPGYFLKDKGVIDESHSQIDLQ
LFRDHLAPALGITHRFVGTEPNCQLTRAYNQKMKTLLAPAIEVVELPRTEKEGAAISASRVRKLYNERNWQALAPLVPSS
TLAFLTRLAAGNTETA

Specific function: Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase [H]

COG id: COG3053

COG function: function code C; Citrate lyase synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Escherichia coli, GI87081765, Length=334, Percent_Identity=49.4011976047904, Blast_Score=327, Evalue=6e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005216
- InterPro:   IPR013166
- InterPro:   IPR004821
- InterPro:   IPR014729 [H]

Pfam domain/function: PF08218 Citrate_ly_lig [H]

EC number: =6.2.1.22 [H]

Molecular weight: Translated: 37636; Mature: 37636

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIFKQCIPQRDARNRARLVEFLSESGLTLEADCEVMVLAEQRGRLVGCGAIAGNVIKD
CCCCHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCEEEEHHHHHHHHHH
IAIDPTARGDGLSLKLLTELLILACEMGRNDLFLFTKPENVVLFSGAGFFPIAQTEHVVL
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCCCEEEE
MENSRERLTRYCRQLALYRQPGNKIGAIVMNANPFTLGHRYLVEQALKQCDWLHIFVVQE
EECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEC
DASFFSYLDRWKLIEQGILGMDRVTLHPGSSYIISRATFPGYFLKDKGVIDESHSQIDLQ
CCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCEEEECCCCCCCCCCHHHHH
LFRDHLAPALGITHRFVGTEPNCQLTRAYNQKMKTLLAPAIEVVELPRTEKEGAAISASR
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECHHH
VRKLYNERNWQALAPLVPSSTLAFLTRLAAGNTETA
HHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNIIFKQCIPQRDARNRARLVEFLSESGLTLEADCEVMVLAEQRGRLVGCGAIAGNVIKD
CCCCHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCEEEEHHHHHHHHHH
IAIDPTARGDGLSLKLLTELLILACEMGRNDLFLFTKPENVVLFSGAGFFPIAQTEHVVL
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCCCEEEE
MENSRERLTRYCRQLALYRQPGNKIGAIVMNANPFTLGHRYLVEQALKQCDWLHIFVVQE
EECCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEEEEC
DASFFSYLDRWKLIEQGILGMDRVTLHPGSSYIISRATFPGYFLKDKGVIDESHSQIDLQ
CCHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCEEEECCCCCCCCCCHHHHH
LFRDHLAPALGITHRFVGTEPNCQLTRAYNQKMKTLLAPAIEVVELPRTEKEGAAISASR
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECHHH
VRKLYNERNWQALAPLVPSSTLAFLTRLAAGNTETA
HHHHHHCCCCEEECCCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7830578 [H]