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The map label for this gene is cysS [H]

Identifier: 218533086

GI number: 218533086

Start: 5577819

End: 5579207

Strand: Reverse

Name: cysS [H]

Synonym: Mchl_5212

Alternate gene names: 218533086

Gene position: 5579207-5577819 (Counterclockwise)

Preceding gene: 218533088

Following gene: 218533083

Centisome position: 96.56

GC content: 68.83

Gene sequence:

>1389_bases
ATGACGCCGATGTTGCGCCTCTACAACACGCTGACCCGCGAGAAGGCGGCCTTCGTGCCGATCGATCCGACGAATGTGCG
GATGTATGCCTGCGGGCCGACAGTTTACGACGCGGCGCATATCGGCAACGCGCGGCCGATCATCGTCTTCGACCTGCTGT
TCCGGCTGCTGCGCCACCTCTACGGGCCGGCGCACGTCACCTATGCCCGCAACGTCACGGACGTGGACGACAAGATCAAC
GCCCGCGCGCTCGAACGCGGCATCACCATCCGCGAACTGACCGATGGCACGCTGGCACAGTTCCACCGGGACATCCGCGA
CCTCGGCGTGCTGATGGCCGACGACGTGAACCGCGCGGGCGAGCCGGCCCGCTTCATCGAGCCGCGGGCGACCGACCACA
TCGCCGAGATGCACCGGCTGATCGAGGGGCTGGTCGCGGCCGGCCACGCCTACGTGGCGGAAGGGCACGTTCTGTTCGAC
GTTCCCTCCATGCCCGATTACGGCGCGCTCTCGAAGCGCCCGCTCGACGAGATGGAATCGGGCGCCCGGGTCGAGGTCGC
ACCCTACAAGCGCTCGCCGCTCGATTTCGTGCTGTGGAAGCCCTCGAAGGCGGGCGAACCGTCCTGGCCCTCACCCTGCG
GGATCGACCTGTCAGGCCGGCCCGGCTGGCACATCGAGTGCTCGGCGATGTCGTGGAAGCATCTGGGCGAAACCTTCGAC
ATCCATGCCGGCGGCCTCGACCTGATCTTCCCCCATCACGAGAACGAGGTGGCCCAGTCGCGCTGCTGCTTCGGCACCGA
CGTGATGGCCCATGTCTGGCTCCACAACGGCTTCCTGCAGGTCGAGGGGGAGAAGATGTCGAAGTCGCTCGGCAACTTCA
TCACCATCCGCCAGGTGCTGGACGACTGGCCGGGCGAGGTCGTGCGCCTCAACATGCTCAAGACCCACTACCGCCAGCCG
ATCGACTGGACCCTGCGCGGCCTCGAGGAATCGAGCCGGATGCTGGACCGTTGGTACGAGGCCGCCGGCGAAGCAAGGCC
CGACGCGGGGGCGCCCGAAGGCGTAGTCGAGGCGCTCTGCGACGACCTGAACACGCCCGCGGCCCTCGGAGAATTGCATC
GCCTTGCCGGCACCAGCCCCTCCGCGCTCAAGGCCGGCGCGGGACTGATGGGTTTCCTGGCCGTCACGCAGGCGCAGCGC
GAGGCGGAGCGGGTCGGCGCGGCCGGCATCGACGTGGCGCGGGTCGAGGCGCTGATCGCCGAGCGCAAGGCGGCCCGCGC
CGCGAAGGACTGGGCGGCCTCCGACCGGGTGCGCGACGCGCTCACCGCCATGGGCGTGAGCGTGAAGGACAACAAGGACG
GCACCACCACCTGGACGGTGGCGGGCTGA

Upstream 100 bases:

>100_bases
CCGTGGGACGGCCGGCGGAAGATGCTGGGCCGCAACGACAAACGACGAGGGCGGCACAGGCCGCAGGGGAGGCCGGGCAA
GCCCGGCAGGAACGCAGTCG

Downstream 100 bases:

>100_bases
AGGGCTGCCCGAACCTTAAGGGATGACTGGCCGAGGTGCGCAGCGCGGAAGCGAATCAGCCCTTCAGCCGCTGCAACCAG
CTGCCACGATGGGCGTAGGA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTPMLRLYNTLTREKAAFVPIDPTNVRMYACGPTVYDAAHIGNARPIIVFDLLFRLLRHLYGPAHVTYARNVTDVDDKIN
ARALERGITIRELTDGTLAQFHRDIRDLGVLMADDVNRAGEPARFIEPRATDHIAEMHRLIEGLVAAGHAYVAEGHVLFD
VPSMPDYGALSKRPLDEMESGARVEVAPYKRSPLDFVLWKPSKAGEPSWPSPCGIDLSGRPGWHIECSAMSWKHLGETFD
IHAGGLDLIFPHHENEVAQSRCCFGTDVMAHVWLHNGFLQVEGEKMSKSLGNFITIRQVLDDWPGEVVRLNMLKTHYRQP
IDWTLRGLEESSRMLDRWYEAAGEARPDAGAPEGVVEALCDDLNTPAALGELHRLAGTSPSALKAGAGLMGFLAVTQAQR
EAERVGAAGIDVARVEALIAERKAARAAKDWAASDRVRDALTAMGVSVKDNKDGTTTWTVAG

Sequences:

>Translated_462_residues
MTPMLRLYNTLTREKAAFVPIDPTNVRMYACGPTVYDAAHIGNARPIIVFDLLFRLLRHLYGPAHVTYARNVTDVDDKIN
ARALERGITIRELTDGTLAQFHRDIRDLGVLMADDVNRAGEPARFIEPRATDHIAEMHRLIEGLVAAGHAYVAEGHVLFD
VPSMPDYGALSKRPLDEMESGARVEVAPYKRSPLDFVLWKPSKAGEPSWPSPCGIDLSGRPGWHIECSAMSWKHLGETFD
IHAGGLDLIFPHHENEVAQSRCCFGTDVMAHVWLHNGFLQVEGEKMSKSLGNFITIRQVLDDWPGEVVRLNMLKTHYRQP
IDWTLRGLEESSRMLDRWYEAAGEARPDAGAPEGVVEALCDDLNTPAALGELHRLAGTSPSALKAGAGLMGFLAVTQAQR
EAERVGAAGIDVARVEALIAERKAARAAKDWAASDRVRDALTAMGVSVKDNKDGTTTWTVAG
>Mature_461_residues
TPMLRLYNTLTREKAAFVPIDPTNVRMYACGPTVYDAAHIGNARPIIVFDLLFRLLRHLYGPAHVTYARNVTDVDDKINA
RALERGITIRELTDGTLAQFHRDIRDLGVLMADDVNRAGEPARFIEPRATDHIAEMHRLIEGLVAAGHAYVAEGHVLFDV
PSMPDYGALSKRPLDEMESGARVEVAPYKRSPLDFVLWKPSKAGEPSWPSPCGIDLSGRPGWHIECSAMSWKHLGETFDI
HAGGLDLIFPHHENEVAQSRCCFGTDVMAHVWLHNGFLQVEGEKMSKSLGNFITIRQVLDDWPGEVVRLNMLKTHYRQPI
DWTLRGLEESSRMLDRWYEAAGEARPDAGAPEGVVEALCDDLNTPAALGELHRLAGTSPSALKAGAGLMGFLAVTQAQRE
AERVGAAGIDVARVEALIAERKAARAAKDWAASDRVRDALTAMGVSVKDNKDGTTTWTVAG

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=520, Percent_Identity=32.5, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI21269877, Length=315, Percent_Identity=34.2857142857143, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI10835051, Length=315, Percent_Identity=34.2857142857143, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI62240992, Length=315, Percent_Identity=34.2857142857143, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI303304987, Length=315, Percent_Identity=34.2857142857143, Blast_Score=174, Evalue=2e-43,
Organism=Escherichia coli, GI1786737, Length=475, Percent_Identity=45.8947368421053, Blast_Score=369, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI17509797, Length=258, Percent_Identity=37.984496124031, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI17509795, Length=258, Percent_Identity=37.984496124031, Blast_Score=157, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6324082, Length=302, Percent_Identity=33.7748344370861, Blast_Score=164, Evalue=4e-41,
Organism=Drosophila melanogaster, GI19922218, Length=519, Percent_Identity=32.1772639691715, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI19922364, Length=320, Percent_Identity=34.375, Blast_Score=169, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 50824; Mature: 50693

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPMLRLYNTLTREKAAFVPIDPTNVRMYACGPTVYDAAHIGNARPIIVFDLLFRLLRHL
CCCHHHHHHHHHHCCCEEEECCCCCEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
YGPAHVTYARNVTDVDDKINARALERGITIRELTDGTLAQFHRDIRDLGVLMADDVNRAG
CCCCEEEEECCCCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCC
EPARFIEPRATDHIAEMHRLIEGLVAAGHAYVAEGHVLFDVPSMPDYGALSKRPLDEMES
CCHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCCCCCCCCCCHHHHHC
GARVEVAPYKRSPLDFVLWKPSKAGEPSWPSPCGIDLSGRPGWHIECSAMSWKHLGETFD
CCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCEEE
IHAGGLDLIFPHHENEVAQSRCCFGTDVMAHVWLHNGFLQVEGEKMSKSLGNFITIRQVL
EECCCEEEECCCCCCHHHHHHCCCCHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHH
DDWPGEVVRLNMLKTHYRQPIDWTLRGLEESSRMLDRWYEAAGEARPDAGAPEGVVEALC
CCCCCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
DDLNTPAALGELHRLAGTSPSALKAGAGLMGFLAVTQAQREAERVGAAGIDVARVEALIA
HCCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ERKAARAAKDWAASDRVRDALTAMGVSVKDNKDGTTTWTVAG
HHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEECC
>Mature Secondary Structure 
TPMLRLYNTLTREKAAFVPIDPTNVRMYACGPTVYDAAHIGNARPIIVFDLLFRLLRHL
CCHHHHHHHHHHCCCEEEECCCCCEEEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHHH
YGPAHVTYARNVTDVDDKINARALERGITIRELTDGTLAQFHRDIRDLGVLMADDVNRAG
CCCCEEEEECCCCCCCHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCC
EPARFIEPRATDHIAEMHRLIEGLVAAGHAYVAEGHVLFDVPSMPDYGALSKRPLDEMES
CCHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEECCEEEEECCCCCCCCCCCCCCHHHHHC
GARVEVAPYKRSPLDFVLWKPSKAGEPSWPSPCGIDLSGRPGWHIECSAMSWKHLGETFD
CCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCHHHCCCEEE
IHAGGLDLIFPHHENEVAQSRCCFGTDVMAHVWLHNGFLQVEGEKMSKSLGNFITIRQVL
EECCCEEEECCCCCCHHHHHHCCCCHHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHHHH
DDWPGEVVRLNMLKTHYRQPIDWTLRGLEESSRMLDRWYEAAGEARPDAGAPEGVVEALC
CCCCCCEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
DDLNTPAALGELHRLAGTSPSALKAGAGLMGFLAVTQAQREAERVGAAGIDVARVEALIA
HCCCCCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ERKAARAAKDWAASDRVRDALTAMGVSVKDNKDGTTTWTVAG
HHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA