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The map label for this gene is mdtA [H]

Identifier: 218532596

GI number: 218532596

Start: 4994268

End: 4995419

Strand: Reverse

Name: mdtA [H]

Synonym: Mchl_4710

Alternate gene names: 218532596

Gene position: 4995419-4994268 (Counterclockwise)

Preceding gene: 218532598

Following gene: 218532595

Centisome position: 86.46

GC content: 71.18

Gene sequence:

>1152_bases
ATGTCCCCACGGCTCCGTCCCGTCCTCACCGCCACCGCCCTCTCGGCCCTCCTCGTGACGGCGGCCTTTCCGGCGGATGC
GCCCGCGACCTCCGCCCTCCCGGAGGCGGAAGACCCGTCCGTCGCGCTGGTGCGGGTCGTGACGGCGACGGAGGGCCCCG
TCACTTCGGATGTGGTGCTCACCGGCGACATCCAGGCCCAGGCCCAGACCAACGTCGCCTTCCGTACCAACGGCAAGGTC
GCCGAACGCCGTGTCGAGGTCGGCGATCACGTCACTGCCGATCAGGTGCTTGCGGTGCTGGAGCCGCTGACGCAGCGGGC
GAACCTCGACAACGCCCGCGCCGCCCTGGTCTCGGCGGAGGCGCAGCTCACCCAGGCCAAGGTGACCTTCGAGCGCCAGA
AGCAGCTCATCAACGGCGGCTACACCACGCGCCCGTCCTACGACAACGCCGAGCAGCAGCTGCGCACCTCCCAAGCCGCG
GTCGATTCGGCCAAGGCGGCGCTCGGCACCGCCGAGGAACAGCTCTCCTATACCGAGCTGCGCGCGGGCGTATCCGGCAT
CGTCCTGAGTCGCACCTTCGAGGTCGGGCAGGTGGTGCAGGCGGGCCAAGCCGTGATGGTGCTGGCCCAGGACGGCCCGC
GCGACGCGGTGTTCAACGTTTACGAGGCGCTGACGGCCCACCCGCCCGGCGACAAGACGATCCACGTCACGCTCCAGTCC
GATCCCGCGGCAGCGGCGACCGGTCACGTGCGCGAAATCTCGCCGACCGTGGACGCGACGAGCGGCACGGTCCGCGTCAA
GGTCGGCTTGGAAGCGACCCCGCCCGCGATGTCGCTCGGCGCCGTGGTGATCGGCCGGGGCCGCTTCGCCTCGCGCGAGG
CCGTGGTGCTGCCCTGGTCGGCGCTCTACCGCTTCGACAACCGGCCGGCGGTGTGGATCTACGATTCCGCCGCGGGCACG
GTCTCGATCCGCGGCGTCGAGATCGACCGCTACGGCTTCGACAACATCGTCCTGAAGGGCGGCGTCAGGTCCGGAGAAAC
GGTGGTGGTCGCCGGCATCCAGTTCCTCCGACCCGGCCAGCACGTCGCGCTGGCGGCACAGGACGCCGCGCCGGAACCGA
CGAAATCCGCGGCGGGGGAGGGCGGACGATGA

Upstream 100 bases:

>100_bases
TCTGGACGGTCGGTAAGATAGGCGATAAGCCTGCGCCGCGAAAGCCGTCCTCTCACGAATCGGCCGTATGCCCCATCCCC
GACGTCCGGAAACTCGGCCG

Downstream 100 bases:

>100_bases
GGCACGCGCTCCTTGTCTGCGCTGTCGTTGCCGGCGCCGCTCCGCTCACCGCCTGCCAGCCGTCGCAGGAGGCGCCCGCA
CCGCCGCCCGTGCGGCCGGT

Product: efflux transporter RND family, MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MSPRLRPVLTATALSALLVTAAFPADAPATSALPEAEDPSVALVRVVTATEGPVTSDVVLTGDIQAQAQTNVAFRTNGKV
AERRVEVGDHVTADQVLAVLEPLTQRANLDNARAALVSAEAQLTQAKVTFERQKQLINGGYTTRPSYDNAEQQLRTSQAA
VDSAKAALGTAEEQLSYTELRAGVSGIVLSRTFEVGQVVQAGQAVMVLAQDGPRDAVFNVYEALTAHPPGDKTIHVTLQS
DPAAAATGHVREISPTVDATSGTVRVKVGLEATPPAMSLGAVVIGRGRFASREAVVLPWSALYRFDNRPAVWIYDSAAGT
VSIRGVEIDRYGFDNIVLKGGVRSGETVVVAGIQFLRPGQHVALAAQDAAPEPTKSAAGEGGR

Sequences:

>Translated_383_residues
MSPRLRPVLTATALSALLVTAAFPADAPATSALPEAEDPSVALVRVVTATEGPVTSDVVLTGDIQAQAQTNVAFRTNGKV
AERRVEVGDHVTADQVLAVLEPLTQRANLDNARAALVSAEAQLTQAKVTFERQKQLINGGYTTRPSYDNAEQQLRTSQAA
VDSAKAALGTAEEQLSYTELRAGVSGIVLSRTFEVGQVVQAGQAVMVLAQDGPRDAVFNVYEALTAHPPGDKTIHVTLQS
DPAAAATGHVREISPTVDATSGTVRVKVGLEATPPAMSLGAVVIGRGRFASREAVVLPWSALYRFDNRPAVWIYDSAAGT
VSIRGVEIDRYGFDNIVLKGGVRSGETVVVAGIQFLRPGQHVALAAQDAAPEPTKSAAGEGGR
>Mature_382_residues
SPRLRPVLTATALSALLVTAAFPADAPATSALPEAEDPSVALVRVVTATEGPVTSDVVLTGDIQAQAQTNVAFRTNGKVA
ERRVEVGDHVTADQVLAVLEPLTQRANLDNARAALVSAEAQLTQAKVTFERQKQLINGGYTTRPSYDNAEQQLRTSQAAV
DSAKAALGTAEEQLSYTELRAGVSGIVLSRTFEVGQVVQAGQAVMVLAQDGPRDAVFNVYEALTAHPPGDKTIHVTLQSD
PAAAATGHVREISPTVDATSGTVRVKVGLEATPPAMSLGAVVIGRGRFASREAVVLPWSALYRFDNRPAVWIYDSAAGTV
SIRGVEIDRYGFDNIVLKGGVRSGETVVVAGIQFLRPGQHVALAAQDAAPEPTKSAAGEGGR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=297, Percent_Identity=25.9259259259259, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI87082036, Length=346, Percent_Identity=24.5664739884393, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87081796, Length=322, Percent_Identity=25.776397515528, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789665, Length=343, Percent_Identity=25.0728862973761, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87081951, Length=204, Percent_Identity=28.921568627451, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40075; Mature: 39943

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRLRPVLTATALSALLVTAAFPADAPATSALPEAEDPSVALVRVVTATEGPVTSDVVL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEE
TGDIQAQAQTNVAFRTNGKVAERRVEVGDHVTADQVLAVLEPLTQRANLDNARAALVSAE
EECCEECEECCEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHEEEHH
AQLTQAKVTFERQKQLINGGYTTRPSYDNAEQQLRTSQAAVDSAKAALGTAEEQLSYTEL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RAGVSGIVLSRTFEVGQVVQAGQAVMVLAQDGPRDAVFNVYEALTAHPPGDKTIHVTLQS
HCCCCEEEEEEEHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECC
DPAAAATGHVREISPTVDATSGTVRVKVGLEATPPAMSLGAVVIGRGRFASREAVVLPWS
CCCCHHCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEEHH
ALYRFDNRPAVWIYDSAAGTVSIRGVEIDRYGFDNIVLKGGVRSGETVVVAGIQFLRPGQ
HHHEECCCCEEEEEECCCCEEEEEEEEEECCCCCCEEEECCCCCCCEEEEECHHHHCCCC
HVALAAQDAAPEPTKSAAGEGGR
EEEEEECCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
SPRLRPVLTATALSALLVTAAFPADAPATSALPEAEDPSVALVRVVTATEGPVTSDVVL
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCEEE
TGDIQAQAQTNVAFRTNGKVAERRVEVGDHVTADQVLAVLEPLTQRANLDNARAALVSAE
EECCEECEECCEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHEEEHH
AQLTQAKVTFERQKQLINGGYTTRPSYDNAEQQLRTSQAAVDSAKAALGTAEEQLSYTEL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RAGVSGIVLSRTFEVGQVVQAGQAVMVLAQDGPRDAVFNVYEALTAHPPGDKTIHVTLQS
HCCCCEEEEEEEHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEEEECC
DPAAAATGHVREISPTVDATSGTVRVKVGLEATPPAMSLGAVVIGRGRFASREAVVLPWS
CCCCHHCCCEEECCCCCCCCCCEEEEEEECCCCCCCCCCCEEEEECCCCCCCCEEEEEHH
ALYRFDNRPAVWIYDSAAGTVSIRGVEIDRYGFDNIVLKGGVRSGETVVVAGIQFLRPGQ
HHHEECCCCEEEEEECCCCEEEEEEEEEECCCCCCEEEECCCCCCCEEEEECHHHHCCCC
HVALAAQDAAPEPTKSAAGEGGR
EEEEEECCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]