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The map label for this gene is bepF [H]

Identifier: 218532595

GI number: 218532595

Start: 4993120

End: 4994271

Strand: Reverse

Name: bepF [H]

Synonym: Mchl_4709

Alternate gene names: 218532595

Gene position: 4994271-4993120 (Counterclockwise)

Preceding gene: 218532596

Following gene: 218532594

Centisome position: 86.44

GC content: 74.39

Gene sequence:

>1152_bases
ATGAGGCACGCGCTCCTTGTCTGCGCTGTCGTTGCCGGCGCCGCTCCGCTCACCGCCTGCCAGCCGTCGCAGGAGGCGCC
CGCACCGCCGCCCGTGCGGCCGGTTCTGACCACCCTGGCACAGCCCACCGACAGCGTGATCTTCGGCCCCTTTGCCGGCA
CGGTCGAGCCGCGCTACCAATCGCAGCTCGGCTTCCAGATCGGCGGACGGGTGGTGGCCCGCGACGTCACCGTCGGCGAC
GTCGTGAAGAAGGGCCAGCGCCTCGCGGCCCTCGACCCGATCGTCTCGCGGTTCGACCTTAGCCGCGCCGAGGCGGAGCT
GTCCGACGCCAGGGCTCAGGCCGAGAACGCGACGGCCACCGAGGCGCGCACGCGGCGCCTGATGGAGGGCGGCAACGTCA
CCCAGGCCCAGCTCGACGCGGCGGTGGCCCGGCGCGACACCGCCCAAGCCCGCCTCGCCCAGGCCGGCGCCAGCCTGCAG
AAGGCCCGCGACCAGATCGGCTACACCGAGTTGCGTGCCGATTTCGACGGCGTCGTCACCCAGCGGCTCGCCGAAATCGG
GCAGGTCGTGAGCCCGGGGCAGGGGATCGTGACGCTGGCCCGGCCCGAGACCCGCGAGGCCGTGGTCGACATCCCCGAGA
CACCGGCCGGCGCCATGCCCAAGGACGGGCTGTTCACGGTGGTGCTCCAGAGCGCGCCGGAGATCACCGCCCGCGGCCGG
GTGCGCGAGGTCGCCCCCTTCGCCGAAGCCGGCACCCGCACCCGCCGGGTCCGCCTGACCCTGGAAGAGCCCGGCCCCGC
CTTCCGGCTCGGCGCCACCATCACCGTCGCGCTGGAGCGCCGCATCGAGCGCCGCTTCGTCCTGCCGGCCACCGCGCTCC
TCGACGCCGATGGCCGCCGCTCGGTCTGGATTGTGCCGGCGGCCGACAAGCGCGGGGACGAGAATGCGGGCAAGCAAGAG
GCCGTGCAGGGCGATGAGCCGGGCGACCGGCACGTCGAGCGCCGCGACGTGACCCTCGACGGGCACGAGCCGGACGGAAA
CGGGCGCATCGCCGTGCGCACGGGGCTGAAACCCGGCGAGCGGGTCGTGGTCGCGGGCGCCCATTCCCTGCGCGAAGGCC
AGACCGTCCGGCTGGCCGACGACCGGAACTGA

Upstream 100 bases:

>100_bases
TCGCCGGCATCCAGTTCCTCCGACCCGGCCAGCACGTCGCGCTGGCGGCACAGGACGCCGCGCCGGAACCGACGAAATCC
GCGGCGGGGGAGGGCGGACG

Downstream 100 bases:

>100_bases
GCCGGAACCCGGCAAGGGATTCGGCCCGGCAAGACATCCGGCAAGACATTCTGCAAAGGTTTCCGCGCGTGAAGGACTTC
AACCTTTCCGATTGGGCGCT

Product: efflux transporter RND family, MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MRHALLVCAVVAGAAPLTACQPSQEAPAPPPVRPVLTTLAQPTDSVIFGPFAGTVEPRYQSQLGFQIGGRVVARDVTVGD
VVKKGQRLAALDPIVSRFDLSRAEAELSDARAQAENATATEARTRRLMEGGNVTQAQLDAAVARRDTAQARLAQAGASLQ
KARDQIGYTELRADFDGVVTQRLAEIGQVVSPGQGIVTLARPETREAVVDIPETPAGAMPKDGLFTVVLQSAPEITARGR
VREVAPFAEAGTRTRRVRLTLEEPGPAFRLGATITVALERRIERRFVLPATALLDADGRRSVWIVPAADKRGDENAGKQE
AVQGDEPGDRHVERRDVTLDGHEPDGNGRIAVRTGLKPGERVVVAGAHSLREGQTVRLADDRN

Sequences:

>Translated_383_residues
MRHALLVCAVVAGAAPLTACQPSQEAPAPPPVRPVLTTLAQPTDSVIFGPFAGTVEPRYQSQLGFQIGGRVVARDVTVGD
VVKKGQRLAALDPIVSRFDLSRAEAELSDARAQAENATATEARTRRLMEGGNVTQAQLDAAVARRDTAQARLAQAGASLQ
KARDQIGYTELRADFDGVVTQRLAEIGQVVSPGQGIVTLARPETREAVVDIPETPAGAMPKDGLFTVVLQSAPEITARGR
VREVAPFAEAGTRTRRVRLTLEEPGPAFRLGATITVALERRIERRFVLPATALLDADGRRSVWIVPAADKRGDENAGKQE
AVQGDEPGDRHVERRDVTLDGHEPDGNGRIAVRTGLKPGERVVVAGAHSLREGQTVRLADDRN
>Mature_383_residues
MRHALLVCAVVAGAAPLTACQPSQEAPAPPPVRPVLTTLAQPTDSVIFGPFAGTVEPRYQSQLGFQIGGRVVARDVTVGD
VVKKGQRLAALDPIVSRFDLSRAEAELSDARAQAENATATEARTRRLMEGGNVTQAQLDAAVARRDTAQARLAQAGASLQ
KARDQIGYTELRADFDGVVTQRLAEIGQVVSPGQGIVTLARPETREAVVDIPETPAGAMPKDGLFTVVLQSAPEITARGR
VREVAPFAEAGTRTRRVRLTLEEPGPAFRLGATITVALERRIERRFVLPATALLDADGRRSVWIVPAADKRGDENAGKQE
AVQGDEPGDRHVERRDVTLDGHEPDGNGRIAVRTGLKPGERVVVAGAHSLREGQTVRLADDRN

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=394, Percent_Identity=24.8730964467005, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081796, Length=361, Percent_Identity=26.8698060941828, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40908; Mature: 40908

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHALLVCAVVAGAAPLTACQPSQEAPAPPPVRPVLTTLAQPTDSVIFGPFAGTVEPRYQ
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCHHH
SQLGFQIGGRVVARDVTVGDVVKKGQRLAALDPIVSRFDLSRAEAELSDARAQAENATAT
HHCCHHHCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EARTRRLMEGGNVTQAQLDAAVARRDTAQARLAQAGASLQKARDQIGYTELRADFDGVVT
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QRLAEIGQVVSPGQGIVTLARPETREAVVDIPETPAGAMPKDGLFTVVLQSAPEITARGR
HHHHHHHHHCCCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCHHCCC
VREVAPFAEAGTRTRRVRLTLEEPGPAFRLGATITVALERRIERRFVLPATALLDADGRR
HHHHCCHHHCCCCEEEEEEEEECCCCCEEECCEEEEHHHHHHHHEECCCHHHEECCCCCC
SVWIVPAADKRGDENAGKQEAVQGDEPGDRHVERRDVTLDGHEPDGNGRIAVRTGLKPGE
EEEEEECCCCCCCCCCCHHHCCCCCCCCCCCHHHCCEEECCCCCCCCCEEEEEECCCCCC
RVVVAGAHSLREGQTVRLADDRN
EEEEECCHHCCCCCEEEECCCCC
>Mature Secondary Structure
MRHALLVCAVVAGAAPLTACQPSQEAPAPPPVRPVLTTLAQPTDSVIFGPFAGTVEPRYQ
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEEECCCCCCCCCHHH
SQLGFQIGGRVVARDVTVGDVVKKGQRLAALDPIVSRFDLSRAEAELSDARAQAENATAT
HHCCHHHCCEEEEECCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
EARTRRLMEGGNVTQAQLDAAVARRDTAQARLAQAGASLQKARDQIGYTELRADFDGVVT
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
QRLAEIGQVVSPGQGIVTLARPETREAVVDIPETPAGAMPKDGLFTVVLQSAPEITARGR
HHHHHHHHHCCCCCCEEEECCCCCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCHHCCC
VREVAPFAEAGTRTRRVRLTLEEPGPAFRLGATITVALERRIERRFVLPATALLDADGRR
HHHHCCHHHCCCCEEEEEEEEECCCCCEEECCEEEEHHHHHHHHEECCCHHHEECCCCCC
SVWIVPAADKRGDENAGKQEAVQGDEPGDRHVERRDVTLDGHEPDGNGRIAVRTGLKPGE
EEEEEECCCCCCCCCCCHHHCCCCCCCCCCCHHHCCEEECCCCCCCCCEEEEEECCCCCC
RVVVAGAHSLREGQTVRLADDRN
EEEEECCHHCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]