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The map label for this gene is zitB [C]

Identifier: 218532574

GI number: 218532574

Start: 4969577

End: 4970599

Strand: Reverse

Name: zitB [C]

Synonym: Mchl_4688

Alternate gene names: 218532574

Gene position: 4970599-4969577 (Counterclockwise)

Preceding gene: 218532576

Following gene: 218532570

Centisome position: 86.03

GC content: 68.04

Gene sequence:

>1023_bases
ATGGCCGAAAGCACGGGTGCGATCTACACGGCGGCGGGCGCCAACCTCGCCATCGCGGCGGCGAAGTTCGTCGGCGCCTT
CCTCACCGGCTCGACCGCGATGCTGGCCGAAGGCGCGCACTCGCTCGTCGACACCGCCAACCAGCTCCTGCTGCTGGTCG
GCCTGAAGCGGGCGAAGAAGCCGGCGGACGCCAAGCATCCCTTCGGCTACGGGCGCGAGGTGTATTTCTACGCCTTCATC
GTTGCCCTGTTCATCTTCCTCGGCGGCGGCATCTTCGCGATCTACGAGGGCGCCCACAAGATCGAGCACCCCGAACCCTC
CGCCGACGCGACCCTGTTCGGCGTTCAGCTCTCCGGCTTCTGGGTGAACGTCTCGATCCTCGGCTTCGCGATCCTAGCGG
AGGGCTATTCCTGCTTCGTGGCCGTGAAGGCGTTCTGGGCGGAGAAGGGCGAGCGCAGCGCCATTACCGCGATTCAGCGC
AGCAAGGACCCGGCGCTCTACACGATCCTCGTGGAGGACGTCGCTGCACTGATCGGCCTCGTCATCGCCATCGGCGGCGT
GGTGCTCGCGCATGTCCTCGACAAGCCGGCACTCGACGGCTGGGCCTCGATCGGCATCGGCCTCGTTCTGATCGGCATGT
CGATCTTCCTGATGATCGAGACCCACGGCCTGCTGATCGGCGAGGCGGCCGACCCGGCGGTGGTGCGCACGATCCAGGCG
GCGGTGTCCGAGGAGAGCGCGGTCCAGCACGTCAACGCGGTGCTGACCCAGCATCTCGGCCCCTCGGATATCCTCGTGAA
CCTCAGCCTCGACTTTGCCGACGAGGTGCCTGCGGGCGAGGTCGAGCGGACGGTGGCGCGGCTGGAGCAGCGGATCAAGG
CGAAGAGCCGCAACGTCACCCGCGTCTTCATCGAGATCCAGTCGCGGAATGCGCATGCCGCCGGGCATGCGCCGACCGAT
GCGTCTACCCCCGCGCCCACGGGCCATGACGCGGCCCCGCCCGGCTCGGCCGTTCCGGCGTGA

Upstream 100 bases:

>100_bases
GGGCGGCACGTTGCACGGGCTGCCTCATCGCAGCAACCTTGACCACTCCGGCGGCGTTGACGAGCCCGTGACGGCGGCGC
GCGCCGCTCAGGAGCGGGAC

Downstream 100 bases:

>100_bases
GGGCTTACCGCTTCACCCCCTCGCGGGCGAGCAGGGCCGTCTTGCGCGCCGTGCCCCAGCGGTAGCCCGACAGCGCCCCG
TCGGAGCGCACCACCCGGTG

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: Cation Efflux Family Protein; Cation Transporter; Cation Efflux Protein; Integral Membrane Protein; Membrane Transporter; Co/Zn/Cd Cation Transporter; Cobalt-Zinc-Cadmium Resistance Protein CzcD; CDF Family Transporter; Cation Diffusion Facilitator Family Protein; Cation Efflux System Protein; Cation Efflux System; Cation-Efflux Pump; Cation Transporter Permease Component; Cation Efflux Transporter; CDF Family Cation Diffusion Facilitator; CDF Family Heavy Metal/H(+) Antiporter; Zinc/Cadmium/Cations Transporter; CDF Family Cation Efflux Protein; Cation Transporter Protein; MMT1 Protein; C-Terminal Region Cation Efflux System Protein CZCD

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MAESTGAIYTAAGANLAIAAAKFVGAFLTGSTAMLAEGAHSLVDTANQLLLLVGLKRAKKPADAKHPFGYGREVYFYAFI
VALFIFLGGGIFAIYEGAHKIEHPEPSADATLFGVQLSGFWVNVSILGFAILAEGYSCFVAVKAFWAEKGERSAITAIQR
SKDPALYTILVEDVAALIGLVIAIGGVVLAHVLDKPALDGWASIGIGLVLIGMSIFLMIETHGLLIGEAADPAVVRTIQA
AVSEESAVQHVNAVLTQHLGPSDILVNLSLDFADEVPAGEVERTVARLEQRIKAKSRNVTRVFIEIQSRNAHAAGHAPTD
ASTPAPTGHDAAPPGSAVPA

Sequences:

>Translated_340_residues
MAESTGAIYTAAGANLAIAAAKFVGAFLTGSTAMLAEGAHSLVDTANQLLLLVGLKRAKKPADAKHPFGYGREVYFYAFI
VALFIFLGGGIFAIYEGAHKIEHPEPSADATLFGVQLSGFWVNVSILGFAILAEGYSCFVAVKAFWAEKGERSAITAIQR
SKDPALYTILVEDVAALIGLVIAIGGVVLAHVLDKPALDGWASIGIGLVLIGMSIFLMIETHGLLIGEAADPAVVRTIQA
AVSEESAVQHVNAVLTQHLGPSDILVNLSLDFADEVPAGEVERTVARLEQRIKAKSRNVTRVFIEIQSRNAHAAGHAPTD
ASTPAPTGHDAAPPGSAVPA
>Mature_339_residues
AESTGAIYTAAGANLAIAAAKFVGAFLTGSTAMLAEGAHSLVDTANQLLLLVGLKRAKKPADAKHPFGYGREVYFYAFIV
ALFIFLGGGIFAIYEGAHKIEHPEPSADATLFGVQLSGFWVNVSILGFAILAEGYSCFVAVKAFWAEKGERSAITAIQRS
KDPALYTILVEDVAALIGLVIAIGGVVLAHVLDKPALDGWASIGIGLVLIGMSIFLMIETHGLLIGEAADPAVVRTIQAA
VSEESAVQHVNAVLTQHLGPSDILVNLSLDFADEVPAGEVERTVARLEQRIKAKSRNVTRVFIEIQSRNAHAAGHAPTDA
STPAPTGHDAAPPGSAVPA

Specific function: Involved In Zinc Efflux Across The Cytoplasmic Membrane, Thus Reducing Zinc Accumulation In The Cytoplasm And Rendering Bacteria More Resistant To Zinc. It May Contribute To Zinc Homeostasis At Low Concentrations Of Zinc, Whereas Znta Is Required For Grow

COG id: COG0053

COG function: function code P; Predicted Co/Zn/Cd cation transporters

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI57164948, Length=257, Percent_Identity=28.7937743190661, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI115534117, Length=260, Percent_Identity=30.3846153846154, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24653141, Length=250, Percent_Identity=28.4, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24653143, Length=250, Percent_Identity=28.4, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35510; Mature: 35379

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAESTGAIYTAAGANLAIAAAKFVGAFLTGSTAMLAEGAHSLVDTANQLLLLVGLKRAKK
CCCCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PADAKHPFGYGREVYFYAFIVALFIFLGGGIFAIYEGAHKIEHPEPSADATLFGVQLSGF
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCCCCCCCCEEEEEEEECE
WVNVSILGFAILAEGYSCFVAVKAFWAEKGERSAITAIQRSKDPALYTILVEDVAALIGL
EEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHH
VIAIGGVVLAHVLDKPALDGWASIGIGLVLIGMSIFLMIETHGLLIGEAADPAVVRTIQA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEECCEEEECCCCHHHHHHHHH
AVSEESAVQHVNAVLTQHLGPSDILVNLSLDFADEVPAGEVERTVARLEQRIKAKSRNVT
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
RVFIEIQSRNAHAAGHAPTDASTPAPTGHDAAPPGSAVPA
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AESTGAIYTAAGANLAIAAAKFVGAFLTGSTAMLAEGAHSLVDTANQLLLLVGLKRAKK
CCCCCCEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PADAKHPFGYGREVYFYAFIVALFIFLGGGIFAIYEGAHKIEHPEPSADATLFGVQLSGF
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCHHCCCCCCCCCCEEEEEEEECE
WVNVSILGFAILAEGYSCFVAVKAFWAEKGERSAITAIQRSKDPALYTILVEDVAALIGL
EEEHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEHHHHHHHHHHHHH
VIAIGGVVLAHVLDKPALDGWASIGIGLVLIGMSIFLMIETHGLLIGEAADPAVVRTIQA
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEECCEEEECCCCHHHHHHHHH
AVSEESAVQHVNAVLTQHLGPSDILVNLSLDFADEVPAGEVERTVARLEQRIKAKSRNVT
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
RVFIEIQSRNAHAAGHAPTDASTPAPTGHDAAPPGSAVPA
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA