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The map label for this gene is dnaX [H]

Identifier: 218532449

GI number: 218532449

Start: 4828936

End: 4830018

Strand: Reverse

Name: dnaX [H]

Synonym: Mchl_4561

Alternate gene names: 218532449

Gene position: 4830018-4828936 (Counterclockwise)

Preceding gene: 218532450

Following gene: 218532447

Centisome position: 83.59

GC content: 74.33

Gene sequence:

>1083_bases
ATGCGGCCTGATTCCGCCCGGACCGCCCGCGATGCCCGCACCGAGGCCGAGGCGGGCGACCTCGCCCACGTCCCGCGCCC
GCGCGAACAGACCCGCCTTTTCGGGCATGGTCACGCGGAAGCGGCCTTCGCGGGGGCGCTGGCCGTGGGCCGGCTCCATC
ATGCCTGGCTGATCGGCGGTCCTGCCGGCATCGGCAAGGCGACGCTGGCCTACCGGGTCGCGCGCCGGCTCGTGGCCGAC
CCGCGCACGCTCCCCTCCCCCGATTCCCTCGACGTACCGGAGGATCACCCGGCCGCGCGCCAGGTGACGGCCCTGTCGCA
CCCGAATCTGGTCGCGCTGCGCCGGGTTCAGGCGCCGGGCGCCAAGACGCTGCCGACCCGCATCTCGGTCGATGCCGCCC
GCGAGGCGCTTGCCCTGTTCGGGGCCACCGCGGGCGGGGAGGGCGGCTGGCGGGTCTGCATCGTCGACAGCGCCGAGGAT
CTGAACGCCAACAGCGCCAACGCGCTCCTGAAGATGATCGAGGAGCCACCGCCCCGCGCCATCTTCCTCATCGTCTCCCA
CGCGCCGGGCCGCCTGCTGCCGACGATCCGCTCGCGCTGCCGGGCCCTGACGCTGCGTGCGCTGCCGGAGGCGGACGTGC
ACGCGATCATCGAAGAATTTCCGGCGCCCTTCGCCCGGCCCGAAGCGGCGGCTCTGGCGCGGGCCGTCTCGCTCTGCGAG
GGCTCGGTCGCCCGCGCGGTGGCGCTTCTCGACCCCGCCACCGCCGCGGTCGAGGCGGAAGTCTCGGCCCTTCTCGCCGG
CCTGCCGGAGCCGGACGGGCGGCGCGTGCTCAAACTGGCCGAAACGCTTGCCGGCCGCGACGCCGAACCTCTGCTCGCCA
CCGTTCTCGACGCGATCCAGCGCTACGTCGCCACCGAGATCGACCGGCGGCAGGGAGAGGGCCCGGCCCGGCTGCTGGCG
CTGGTGGAGACCGCCGAGCGCATCGCATCCTCGGCCCGCGAGGCCGCGATCTACAATCTCGACCGCCGGCCACTGGTGCT
CGCGGCGTTCCGTGAATTGGCGGCGGCGACGCGGATTCCGTAG

Upstream 100 bases:

>100_bases
GCCATCGCCGCCCGATGGCCGGATCTGCTGCCCCCCGCGGGAGAAGGGCAGGGGCAAGAGGGTAAGAACCGGGAGGGCAA
GGACCGGGAAGGACAAGGTC

Downstream 100 bases:

>100_bases
CCGTCTCGATGGCTGAAAAGTGCGCCTACCGGATCGCGCGCGGATCGTTAGATCAAAGCACTGATCAGGGTGGTTGCACC
GATCAGGACCACGCAGGCGC

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRPDSARTARDARTEAEAGDLAHVPRPREQTRLFGHGHAEAAFAGALAVGRLHHAWLIGGPAGIGKATLAYRVARRLVAD
PRTLPSPDSLDVPEDHPAARQVTALSHPNLVALRRVQAPGAKTLPTRISVDAAREALALFGATAGGEGGWRVCIVDSAED
LNANSANALLKMIEEPPPRAIFLIVSHAPGRLLPTIRSRCRALTLRALPEADVHAIIEEFPAPFARPEAAALARAVSLCE
GSVARAVALLDPATAAVEAEVSALLAGLPEPDGRRVLKLAETLAGRDAEPLLATVLDAIQRYVATEIDRRQGEGPARLLA
LVETAERIASSAREAAIYNLDRRPLVLAAFRELAAATRIP

Sequences:

>Translated_360_residues
MRPDSARTARDARTEAEAGDLAHVPRPREQTRLFGHGHAEAAFAGALAVGRLHHAWLIGGPAGIGKATLAYRVARRLVAD
PRTLPSPDSLDVPEDHPAARQVTALSHPNLVALRRVQAPGAKTLPTRISVDAAREALALFGATAGGEGGWRVCIVDSAED
LNANSANALLKMIEEPPPRAIFLIVSHAPGRLLPTIRSRCRALTLRALPEADVHAIIEEFPAPFARPEAAALARAVSLCE
GSVARAVALLDPATAAVEAEVSALLAGLPEPDGRRVLKLAETLAGRDAEPLLATVLDAIQRYVATEIDRRQGEGPARLLA
LVETAERIASSAREAAIYNLDRRPLVLAAFRELAAATRIP
>Mature_360_residues
MRPDSARTARDARTEAEAGDLAHVPRPREQTRLFGHGHAEAAFAGALAVGRLHHAWLIGGPAGIGKATLAYRVARRLVAD
PRTLPSPDSLDVPEDHPAARQVTALSHPNLVALRRVQAPGAKTLPTRISVDAAREALALFGATAGGEGGWRVCIVDSAED
LNANSANALLKMIEEPPPRAIFLIVSHAPGRLLPTIRSRCRALTLRALPEADVHAIIEEFPAPFARPEAAALARAVSLCE
GSVARAVALLDPATAAVEAEVSALLAGLPEPDGRRVLKLAETLAGRDAEPLLATVLDAIQRYVATEIDRRQGEGPARLLA
LVETAERIASSAREAAIYNLDRRPLVLAAFRELAAATRIP

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG0470

COG function: function code L; ATPase involved in DNA replication

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=292, Percent_Identity=29.4520547945205, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 38130; Mature: 38130

Theoretical pI: Translated: 8.14; Mature: 8.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPDSARTARDARTEAEAGDLAHVPRPREQTRLFGHGHAEAAFAGALAVGRLHHAWLIGG
CCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEEC
PAGIGKATLAYRVARRLVADPRTLPSPDSLDVPEDHPAARQVTALSHPNLVALRRVQAPG
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHEECCCC
AKTLPTRISVDAAREALALFGATAGGEGGWRVCIVDSAEDLNANSANALLKMIEEPPPRA
CCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCE
IFLIVSHAPGRLLPTIRSRCRALTLRALPEADVHAIIEEFPAPFARPEAAALARAVSLCE
EEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
GSVARAVALLDPATAAVEAEVSALLAGLPEPDGRRVLKLAETLAGRDAEPLLATVLDAIQ
CHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RYVATEIDRRQGEGPARLLALVETAERIASSAREAAIYNLDRRPLVLAAFRELAAATRIP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRPDSARTARDARTEAEAGDLAHVPRPREQTRLFGHGHAEAAFAGALAVGRLHHAWLIGG
CCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHEEEEEC
PAGIGKATLAYRVARRLVADPRTLPSPDSLDVPEDHPAARQVTALSHPNLVALRRVQAPG
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHEECCCC
AKTLPTRISVDAAREALALFGATAGGEGGWRVCIVDSAEDLNANSANALLKMIEEPPPRA
CCCCCCEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCE
IFLIVSHAPGRLLPTIRSRCRALTLRALPEADVHAIIEEFPAPFARPEAAALARAVSLCE
EEEEEECCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
GSVARAVALLDPATAAVEAEVSALLAGLPEPDGRRVLKLAETLAGRDAEPLLATVLDAIQ
CHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHH
RYVATEIDRRQGEGPARLLALVETAERIASSAREAAIYNLDRRPLVLAAFRELAAATRIP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]