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The map label for this gene is ycfH [C]

Identifier: 218532445

GI number: 218532445

Start: 4825534

End: 4826331

Strand: Reverse

Name: ycfH [C]

Synonym: Mchl_4557

Alternate gene names: 218532445

Gene position: 4826331-4825534 (Counterclockwise)

Preceding gene: 218532446

Following gene: 218532444

Centisome position: 83.53

GC content: 71.05

Gene sequence:

>798_bases
ATGCTGGTCGACAGCCACTGCCACCTCGATTTCCCGGACTTCGCGCAGGACATTCCGGGTGTGATCGCCCGCGCGGCGCA
AGCCGGCGTGACGCGCCTCCTCACCATCTCGACGCGGGTCGCCAAGGCCGACAGCTACCGCGCGCTCGCCGAGGCGAACG
CGGCGGTCTGGTACACGGTGGGCACCCACCCGCACGGCGCCGCCGAGGAGCCGGACGTGCCGGCCGAGACCATCGCCGCG
CTGGCCGATGCCCCGCGCTGCGTCGGCATCGGCGAGGCGGGGCTCGACTACCATTACGAGGACGCCGCGCCGGAGGCGGT
GCAGGAGCGGGTGCTGCGCGCCCATATCGAAGCCGCCCGCCTCTCCGGCCTGCCGCTGGTAATCCATTCCCGCGACGCCG
ACGCGCATATGGAGGCGGTGCTCACCGACGAGATGGCAAGGCGGCCGTTCAAGGCGGTGCTGCACTGCTTCTCGTCGGGC
GCGCGGCTTGCTGAAGTCGGGGTGGAGCTCGGCCTGTCGGTCTCGTTCTCCGGCATCGTCACCTTCCGCCGCTCGGACGC
TTTGCGCGACATCGCCCGCAGCGTGCCCCTCGATCGCATCCTGGTCGAGACCGACGCGCCGTTCCTCGCGCCCGAGCCAC
ACCGGGGGCGACGCTGCGAGCCGGCCTACACTGCCGACACCGCCCGCGTGCTGGCCAAGGCGCTCGACTTGCCCTTCGAG
GAGTTTTCCGCGCGCACGACGGCCAACTTCTACCGGTTGTTCTCGAAGGCCGCCGCGATCGAGGGAATCGCCGCATGA

Upstream 100 bases:

>100_bases
GCCCCGGCCCCGATCTTCCCCCGCTTCGAGAAGCCGGAGGCGACGGCCTGACGCCGCCTCCCCGCATCGCTCCTTCCCCA
AAGAATCCGCCAAAGAGACC

Downstream 100 bases:

>100_bases
GGATGGGGGAGGGCGCATGCCGAGCTTGAGCCTGCGCATCCTCGGCTGCGGCTCGTCCGGCGGCGTGCCGCGGGTGGGTT
ACGGCTGGGGCGCCTGCGAC

Product: hydrolase, TatD family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLVDSHCHLDFPDFAQDIPGVIARAAQAGVTRLLTISTRVAKADSYRALAEANAAVWYTVGTHPHGAAEEPDVPAETIAA
LADAPRCVGIGEAGLDYHYEDAAPEAVQERVLRAHIEAARLSGLPLVIHSRDADAHMEAVLTDEMARRPFKAVLHCFSSG
ARLAEVGVELGLSVSFSGIVTFRRSDALRDIARSVPLDRILVETDAPFLAPEPHRGRRCEPAYTADTARVLAKALDLPFE
EFSARTTANFYRLFSKAAAIEGIAA

Sequences:

>Translated_265_residues
MLVDSHCHLDFPDFAQDIPGVIARAAQAGVTRLLTISTRVAKADSYRALAEANAAVWYTVGTHPHGAAEEPDVPAETIAA
LADAPRCVGIGEAGLDYHYEDAAPEAVQERVLRAHIEAARLSGLPLVIHSRDADAHMEAVLTDEMARRPFKAVLHCFSSG
ARLAEVGVELGLSVSFSGIVTFRRSDALRDIARSVPLDRILVETDAPFLAPEPHRGRRCEPAYTADTARVLAKALDLPFE
EFSARTTANFYRLFSKAAAIEGIAA
>Mature_265_residues
MLVDSHCHLDFPDFAQDIPGVIARAAQAGVTRLLTISTRVAKADSYRALAEANAAVWYTVGTHPHGAAEEPDVPAETIAA
LADAPRCVGIGEAGLDYHYEDAAPEAVQERVLRAHIEAARLSGLPLVIHSRDADAHMEAVLTDEMARRPFKAVLHCFSSG
ARLAEVGVELGLSVSFSGIVTFRRSDALRDIARSVPLDRILVETDAPFLAPEPHRGRRCEPAYTADTARVLAKALDLPFE
EFSARTTANFYRLFSKAAAIEGIAA

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=270, Percent_Identity=27.037037037037, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI110349730, Length=267, Percent_Identity=31.0861423220974, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI226061614, Length=257, Percent_Identity=30.3501945525292, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI14042943, Length=201, Percent_Identity=27.363184079602, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI110349734, Length=267, Percent_Identity=31.0861423220974, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI226061853, Length=274, Percent_Identity=30.6569343065693, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI225903439, Length=169, Percent_Identity=28.4023668639053, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226061595, Length=234, Percent_Identity=30.3418803418803, Blast_Score=75, Evalue=8e-14,
Organism=Escherichia coli, GI1787342, Length=257, Percent_Identity=40.8560311284047, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87082439, Length=259, Percent_Identity=32.4324324324324, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI48994985, Length=262, Percent_Identity=32.4427480916031, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=217, Percent_Identity=31.3364055299539, Blast_Score=116, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17565396, Length=307, Percent_Identity=28.9902280130293, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71980746, Length=263, Percent_Identity=26.615969581749, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17543026, Length=293, Percent_Identity=25.938566552901, Blast_Score=81, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24648690, Length=237, Percent_Identity=29.1139240506329, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586117, Length=273, Percent_Identity=24.9084249084249, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI221330018, Length=273, Percent_Identity=24.9084249084249, Blast_Score=74, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28551; Mature: 28551

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS01137 TATD_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVDSHCHLDFPDFAQDIPGVIARAAQAGVTRLLTISTRVAKADSYRALAEANAAVWYTV
CEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GTHPHGAAEEPDVPAETIAALADAPRCVGIGEAGLDYHYEDAAPEAVQERVLRAHIEAAR
CCCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LSGLPLVIHSRDADAHMEAVLTDEMARRPFKAVLHCFSSGARLAEVGVELGLSVSFSGIV
HCCCEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEE
TFRRSDALRDIARSVPLDRILVETDAPFLAPEPHRGRRCEPAYTADTARVLAKALDLPFE
EEHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHH
EFSARTTANFYRLFSKAAAIEGIAA
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLVDSHCHLDFPDFAQDIPGVIARAAQAGVTRLLTISTRVAKADSYRALAEANAAVWYTV
CEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
GTHPHGAAEEPDVPAETIAALADAPRCVGIGEAGLDYHYEDAAPEAVQERVLRAHIEAAR
CCCCCCCCCCCCCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
LSGLPLVIHSRDADAHMEAVLTDEMARRPFKAVLHCFSSGARLAEVGVELGLSVSFSGIV
HCCCEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEEE
TFRRSDALRDIARSVPLDRILVETDAPFLAPEPHRGRRCEPAYTADTARVLAKALDLPFE
EEHHHHHHHHHHHHCCHHHEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHH
EFSARTTANFYRLFSKAAAIEGIAA
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12522265 [H]