Click here to switch to the map view.

The map label for this gene is fadE25 [H]

Identifier: 218532360

GI number: 218532360

Start: 4733718

End: 4735481

Strand: Reverse

Name: fadE25 [H]

Synonym: Mchl_4472

Alternate gene names: 218532360

Gene position: 4735481-4733718 (Counterclockwise)

Preceding gene: 218532362

Following gene: 218532358

Centisome position: 81.96

GC content: 71.54

Gene sequence:

>1764_bases
ATGAGCTATCGCGCGCCCGTCGAGGAGATGGCCTTCACCCTCCGCCACGTCGCGGGGCTCGACGCCGTGCTGGCGCAGGG
CGGGGCCGAGATCGGCCCGGACGATGCGGTCGCCATCCTCGAAGAGGCGGGCCGGCTCGCCGGCAACGTCATCGCCCCGC
TCAACCGGGTCGGCGACCGCCACGGTACGCCGTTCTCGGACGGCCGCGTCACCACCGCGCCGGGCTGGGCGTCAGCCTAC
CGCACCTTCGTCGAGGGCGGCTGGAACGGCGTGCTCGCCGCGCCCGATTACGGGGGGCAGGGCCTGCCGCATCTGATCGC
CGCCGCCTGCACCGAGATGTGGAACGGGGCCAACCTCGCCTTCGGCCTGTGCCCGCTGCTGACCGCCGGCGGCGTCGAGG
CGCTGGCCGCCCACGGCTCCGACGAGCTGAAGGGGCGCTACCTCGAAAAGCTCGTCTCGGGCGAGTGGACCGCGACCATG
AACCTGACCGAGCCGCAGGCGGGCTCGGACCTTTCGGCTCTGCGCACCCGCGCCGAGGCCCAGGGCGACGGCAGCTATCG
GATCACCGGCGCCAAGATCTACATCACCTATGGCGAGCACGACCTTGCCGACAACATCTGCCATCTCGTGCTCGCCCGCC
TCAAGGACGCGCCGGCCGGCACCCGCGGCATCTCGCTGTTCCTCGTACCGAAGGTGCTGCCGGACGGGAGCCGCAACGAC
CTGCGGTGTTCGGGCATCGAGCACAAGCTCGGCATCCACGCCTCGCCGACCTGCTCCATGGCCTTCGGTGACGCGGGCGG
CGCGACCGGCTGGCTGATCGGCGAGGAGAACCGGGGGCTGGCCTGCATGTTCACGATGATGAACTCGGCCCGGCTCAATG
TCGGGCTGCAGGGCGTCGGCGTGGCAGAAGCCGCGTATCAGAAGGCCCTCGACTACGCCCGCGAGCGCCGCCAGGGCCGG
GCGCCGGGCACGCCCGAGCCGGTCAGCGCGATCGTGGCGCATGCCGACATCCAGCGCACGCTGCTGACGATGAAGGCCTA
CACGGCGGCGTCCCGCGGCATCTGCTACCTCACCGCGCAAGGCCTCGACGCCGCTGATGGACCCGAGGGAAAGGCGGCGC
ATGACCGCGCCTCGCTGCTGACGCCGGTGGCCAAAGCCTTCTCCACCGACATCGCCAACGAGGTGACCTCGCTCGGCGTT
CAGGTCCATGGCGGCATGGGCTTCGTCGAGGAAACGGGGGCGGCCCAGCTCATGCGCGATGCCCGCATCCTCGGCATCTA
TGAGGGCACCAACGGCATCCAGGCGATCGATCTCGTCACCCGCAAGCTGCCGCTCAACGGCGGCGCCACGGTCGGCGCGC
AGATCGCGTCGATGCGGCGTGTGGCGGAGGGGCTCTTGAAGGACGGCGCGCCCGGCTTCGGCCACGCGGCGGCGCGCCTG
CGCGAGGGCATCGGCAGTCTCGACCGGGCGACGAGTTTCCTGCTCAAGGCGCTGGCCTCGAACCGCCCGCAGGAGGCTTT
GCCCGGCGCGACGCCGTATCTGCGCCTGTTCGGCCTCGTGCAGGGCGCGGCCTGCCTTGCGACGGCGGGGTTGGCTTCGA
GCGCGGCCGTGAAGGCCGGCGAGACCGATCCGGCCCACGCCGCGCGCATCGCACTCGCCCGCTTCTTTGCCGAGAACCTG
CTGCCGGCGGCAGGCGGCTTGGAGCAGTCGATTCTCTCGGGCGGCGATTTCGCCGACGATCCCGCCTTCGCGCTTGCGGG
GTGA

Upstream 100 bases:

>100_bases
GATGCGAGGAAGAACGGCCGGCCGTAGACCCTTCAGCCGCAAGCCGTCAAACGGGATCGCCGCCCCCTCGACGCGCGGCG
GGAGGAGCGGTGTACCGGTC

Downstream 100 bases:

>100_bases
ACCCGCTCAGCGCTCCGCGCCGGGGCCATACCCCGCGAAAAACACCCGCACCGCCTCCGCGACCCGGTGCCGGATCTCGT
CCTCGTCGGGTGCCTGCCCG

Product: acyl-CoA dehydrogenase domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 586

Protein sequence:

>587_residues
MSYRAPVEEMAFTLRHVAGLDAVLAQGGAEIGPDDAVAILEEAGRLAGNVIAPLNRVGDRHGTPFSDGRVTTAPGWASAY
RTFVEGGWNGVLAAPDYGGQGLPHLIAAACTEMWNGANLAFGLCPLLTAGGVEALAAHGSDELKGRYLEKLVSGEWTATM
NLTEPQAGSDLSALRTRAEAQGDGSYRITGAKIYITYGEHDLADNICHLVLARLKDAPAGTRGISLFLVPKVLPDGSRND
LRCSGIEHKLGIHASPTCSMAFGDAGGATGWLIGEENRGLACMFTMMNSARLNVGLQGVGVAEAAYQKALDYARERRQGR
APGTPEPVSAIVAHADIQRTLLTMKAYTAASRGICYLTAQGLDAADGPEGKAAHDRASLLTPVAKAFSTDIANEVTSLGV
QVHGGMGFVEETGAAQLMRDARILGIYEGTNGIQAIDLVTRKLPLNGGATVGAQIASMRRVAEGLLKDGAPGFGHAAARL
REGIGSLDRATSFLLKALASNRPQEALPGATPYLRLFGLVQGAACLATAGLASSAAVKAGETDPAHAARIALARFFAENL
LPAAGGLEQSILSGGDFADDPAFALAG

Sequences:

>Translated_587_residues
MSYRAPVEEMAFTLRHVAGLDAVLAQGGAEIGPDDAVAILEEAGRLAGNVIAPLNRVGDRHGTPFSDGRVTTAPGWASAY
RTFVEGGWNGVLAAPDYGGQGLPHLIAAACTEMWNGANLAFGLCPLLTAGGVEALAAHGSDELKGRYLEKLVSGEWTATM
NLTEPQAGSDLSALRTRAEAQGDGSYRITGAKIYITYGEHDLADNICHLVLARLKDAPAGTRGISLFLVPKVLPDGSRND
LRCSGIEHKLGIHASPTCSMAFGDAGGATGWLIGEENRGLACMFTMMNSARLNVGLQGVGVAEAAYQKALDYARERRQGR
APGTPEPVSAIVAHADIQRTLLTMKAYTAASRGICYLTAQGLDAADGPEGKAAHDRASLLTPVAKAFSTDIANEVTSLGV
QVHGGMGFVEETGAAQLMRDARILGIYEGTNGIQAIDLVTRKLPLNGGATVGAQIASMRRVAEGLLKDGAPGFGHAAARL
REGIGSLDRATSFLLKALASNRPQEALPGATPYLRLFGLVQGAACLATAGLASSAAVKAGETDPAHAARIALARFFAENL
LPAAGGLEQSILSGGDFADDPAFALAG
>Mature_586_residues
SYRAPVEEMAFTLRHVAGLDAVLAQGGAEIGPDDAVAILEEAGRLAGNVIAPLNRVGDRHGTPFSDGRVTTAPGWASAYR
TFVEGGWNGVLAAPDYGGQGLPHLIAAACTEMWNGANLAFGLCPLLTAGGVEALAAHGSDELKGRYLEKLVSGEWTATMN
LTEPQAGSDLSALRTRAEAQGDGSYRITGAKIYITYGEHDLADNICHLVLARLKDAPAGTRGISLFLVPKVLPDGSRNDL
RCSGIEHKLGIHASPTCSMAFGDAGGATGWLIGEENRGLACMFTMMNSARLNVGLQGVGVAEAAYQKALDYARERRQGRA
PGTPEPVSAIVAHADIQRTLLTMKAYTAASRGICYLTAQGLDAADGPEGKAAHDRASLLTPVAKAFSTDIANEVTSLGVQ
VHGGMGFVEETGAAQLMRDARILGIYEGTNGIQAIDLVTRKLPLNGGATVGAQIASMRRVAEGLLKDGAPGFGHAAARLR
EGIGSLDRATSFLLKALASNRPQEALPGATPYLRLFGLVQGAACLATAGLASSAAVKAGETDPAHAARIALARFFAENLL
PAAGGLEQSILSGGDFADDPAFALAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=403, Percent_Identity=27.7915632754342, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI21361497, Length=354, Percent_Identity=28.2485875706215, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4501857, Length=313, Percent_Identity=26.8370607028754, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI226958414, Length=350, Percent_Identity=28, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI226958412, Length=350, Percent_Identity=28, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI4557235, Length=406, Percent_Identity=26.3546798029557, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI76496475, Length=406, Percent_Identity=26.3546798029557, Blast_Score=109, Evalue=9e-24,
Organism=Homo sapiens, GI7656849, Length=366, Percent_Identity=27.8688524590164, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI4557233, Length=296, Percent_Identity=31.0810810810811, Blast_Score=103, Evalue=7e-22,
Organism=Homo sapiens, GI4557231, Length=307, Percent_Identity=28.9902280130293, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI187960098, Length=307, Percent_Identity=28.9902280130293, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI4503943, Length=310, Percent_Identity=29.0322580645161, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082384, Length=281, Percent_Identity=31.6725978647687, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87081958, Length=311, Percent_Identity=26.6881028938907, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786223, Length=310, Percent_Identity=24.5161290322581, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71985184, Length=422, Percent_Identity=27.0142180094787, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17538396, Length=396, Percent_Identity=27.5252525252525, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17508101, Length=402, Percent_Identity=28.1094527363184, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17534899, Length=368, Percent_Identity=31.25, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=350, Percent_Identity=29.7142857142857, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17570075, Length=354, Percent_Identity=29.0960451977401, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=394, Percent_Identity=26.3959390862944, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17551932, Length=366, Percent_Identity=28.6885245901639, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI86563381, Length=332, Percent_Identity=28.3132530120482, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI86563383, Length=332, Percent_Identity=28.3132530120482, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17505929, Length=365, Percent_Identity=27.9452054794521, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17533517, Length=360, Percent_Identity=27.5, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71985192, Length=327, Percent_Identity=26.2996941896024, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71990804, Length=235, Percent_Identity=27.2340425531915, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=188, Percent_Identity=30.3191489361702, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=281, Percent_Identity=25.6227758007117, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534353, Length=399, Percent_Identity=27.0676691729323, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21355753, Length=420, Percent_Identity=27.3809523809524, Blast_Score=122, Evalue=9e-28,
Organism=Drosophila melanogaster, GI24660351, Length=332, Percent_Identity=31.3253012048193, Blast_Score=115, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24646207, Length=365, Percent_Identity=27.9452054794521, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281363737, Length=334, Percent_Identity=26.0479041916168, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21356377, Length=355, Percent_Identity=29.2957746478873, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24666513, Length=403, Percent_Identity=27.0471464019851, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI19920834, Length=307, Percent_Identity=28.3387622149837, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 60716; Mature: 60584

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYRAPVEEMAFTLRHVAGLDAVLAQGGAEIGPDDAVAILEEAGRLAGNVIAPLNRVGDR
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCC
HGTPFSDGRVTTAPGWASAYRTFVEGGWNGVLAAPDYGGQGLPHLIAAACTEMWNGANLA
CCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCHH
FGLCPLLTAGGVEALAAHGSDELKGRYLEKLVSGEWTATMNLTEPQAGSDLSALRTRAEA
HHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHC
QGDGSYRITGAKIYITYGEHDLADNICHLVLARLKDAPAGTRGISLFLVPKVLPDGSRND
CCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCC
LRCSGIEHKLGIHASPTCSMAFGDAGGATGWLIGEENRGLACMFTMMNSARLNVGLQGVG
EEECCCCHHCCCCCCCCCEEEECCCCCCCEEEEECCCCCEEEEEEHHCCCEECCCCCCCC
VAEAAYQKALDYARERRQGRAPGTPEPVSAIVAHADIQRTLLTMKAYTAASRGICYLTAQ
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GLDAADGPEGKAAHDRASLLTPVAKAFSTDIANEVTSLGVQVHGGMGFVEETGAAQLMRD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHCCHHHHHHC
ARILGIYEGTNGIQAIDLVTRKLPLNGGATVGAQIASMRRVAEGLLKDGAPGFGHAAARL
CEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
REGIGSLDRATSFLLKALASNRPQEALPGATPYLRLFGLVQGAACLATAGLASSAAVKAG
HHHHCHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
ETDPAHAARIALARFFAENLLPAAGGLEQSILSGGDFADDPAFALAG
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SYRAPVEEMAFTLRHVAGLDAVLAQGGAEIGPDDAVAILEEAGRLAGNVIAPLNRVGDR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCC
HGTPFSDGRVTTAPGWASAYRTFVEGGWNGVLAAPDYGGQGLPHLIAAACTEMWNGANLA
CCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCHH
FGLCPLLTAGGVEALAAHGSDELKGRYLEKLVSGEWTATMNLTEPQAGSDLSALRTRAEA
HHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHC
QGDGSYRITGAKIYITYGEHDLADNICHLVLARLKDAPAGTRGISLFLVPKVLPDGSRND
CCCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCC
LRCSGIEHKLGIHASPTCSMAFGDAGGATGWLIGEENRGLACMFTMMNSARLNVGLQGVG
EEECCCCHHCCCCCCCCCEEEECCCCCCCEEEEECCCCCEEEEEEHHCCCEECCCCCCCC
VAEAAYQKALDYARERRQGRAPGTPEPVSAIVAHADIQRTLLTMKAYTAASRGICYLTAQ
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GLDAADGPEGKAAHDRASLLTPVAKAFSTDIANEVTSLGVQVHGGMGFVEETGAAQLMRD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHCCHHHHHHC
ARILGIYEGTNGIQAIDLVTRKLPLNGGATVGAQIASMRRVAEGLLKDGAPGFGHAAARL
CEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
REGIGSLDRATSFLLKALASNRPQEALPGATPYLRLFGLVQGAACLATAGLASSAAVKAG
HHHHCHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
ETDPAHAARIALARFFAENLLPAAGGLEQSILSGGDFADDPAFALAG
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]