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The map label for this gene is atoS [C]

Identifier: 218532309

GI number: 218532309

Start: 4678000

End: 4680351

Strand: Reverse

Name: atoS [C]

Synonym: Mchl_4421

Alternate gene names: 218532309

Gene position: 4680351-4678000 (Counterclockwise)

Preceding gene: 218532310

Following gene: 218532303

Centisome position: 81.0

GC content: 71.73

Gene sequence:

>2352_bases
ATGCCCGAAAGTCTTCCCTCTCCCGTGCCATCCGACGCCGAATCGGCGCGCTTTCGGATCCTGGAGCCGTTGCGGGCGGC
GCAGGAACAGCTCGCCCGCGTGCAGGATGCCGCCGGGATCGGTGTCTTCACCCTCGACCTGCGCGAGGGCGTGCTGCATC
CAAGCCCCGCCTTCTGCCGCCTGCACGGCCTGGAGGTGCGCGAGCGATACGCCCTCGCCGCCCTCGCCGAGCGCTTCCCG
GCGGAGGATACGGCGATCCCCTCGGGTACGTCCTCCGAGGAGGCGGTCTACCGCGTCCGCGATTCCCGGACCGGGGCGTC
GCGCTGGATTGCCCGCACCCTCGAGATCGAGCGCGATGCGGACGGCGCGGCCCTGCGGCTCGCAGGCGTGGTGCGGGACG
TGACCGAGCAGCGGGCCCAGGGCACGGCGCTGGCCGAGAGTGAGCAGCACTACCGCACGCTGTTCGAGCAGATGGACGAG
GGCTACTCCGTCATCGAGTTCATCGATGGCCCGCACGGCCCCTTGAGCGACTACGTCCACGTCACCGCCAACCGCGCCTA
CGCCCAGCATGCCGGCATCGAGAACGTGGCCGGCAAGCGCCTGCGCGAGATCGTCGGCGAGGAGGCCGAGGGCTGGCTCG
CGCTCTACGGCGACGTCCTGCGCACCGGCCGGCCGATCCGCTTCCAGCGCGAGCTGGTCGCTACCGGGCGCTACCTCGAA
CTCGCCGCCTTCCGCATCGAGCCGCCGTCGCGGCGGCAGGTCGCGGTGCTGTTCCAGGACATCACGGCCCGGCGGCGCGT
GGAGCACCTGCTCCATTCCAAGGCTGCCGACCTGGAGGCGGAGGTGGTGGCGCAACGGCGCGACCGCGACCGCGTCTGGA
CGCTCTCGCCGGTCCTCAAGGTCGTGGCCACCCCCGACGGGCGGATCGAGGCGGTGAACCCCTCGTGGGGCCGGACGCTG
GGCTGGTCGCCGGCCGAAACGGTGGGCCGCTACGTGCCCGACTTCTTCGCACCCGAGGAGCGCGCGGCCGCCGAAGCGGC
GCTGGAACGGCTCGCGGCCGGCGCCTCGACCGATCTCGAACTGACCTGCCTGACCAAGGACGGCGGCACCTGCCGGGTGC
TCTGGACCATCGTGCCGGCCGACGGCCTGCTCTACGGCTTCGGCCGCGACATCACCGAGCAGCGCCACGCCGAGGAGGCC
CTGCGCCAATCGCAGAAGCTGGAGGCGGTGGGCCAGCTCACCGGGGGCGTGGCCCACGACTTCAACAACCTGCTCACCAT
CATCCGCTCCTCGGTCGAGTTCCTGCGCCGGCCCGACCTCGCGCCCGAGCGCAAGCGCCGCTACCTCGACGCGGTCTCCG
ACACGGTGGACCGGGCGGCGAAGCTGACGGGTCAACTCCTCGCCTTCGCCCGGCGGCAGGCGCTCAAGCCCGAGACCTTC
GATGTCGGCGAGCGGCTGCGCAGCATCTCGGAGATGCTCGATTCGGTGACCGGCGCGCGCATCCGCGTGGTGACCGACCT
GCCCGGCGCCCCCTGCTTCGTGCGCGCCGATGCGAGCCAGTTCGAGACGGCCCTGGTCAACATGGCGGTCAATGCCCGCG
ACGCCATGGACGGCGAGGGCCGCCTGACCCTGCGCCTCGACGGCGCCGTCCCGATGCCGCCGATCCGCGGCCATGCCGGC
GCGGCCGGGCCCTTCGTCGCGGTTTCGGTCGTCGACACCGGCACCGGGATCGCCAGTGCCGACCTCGGCCGCATCTTCGA
GCCGTTCTTCACCACCAAGGAGGTCGGACGGGGCACGGGGCTCGGCCTCTCCCAGGTGATCGGCTTTGCCAAGCAATCGG
GCGGAGACGTGGACGTGTGGAGCCGCGCGGGTGAGGGCACCACCTTCACCCTCTACCTGCCCGAGGTGGCCGCCCCCCTC
GAAGCCCCCGCCCCCGCTCGGCCGAGGCCGGATGCGGATGCCGAGGCGCATCTGCGGATCCTCGTGGTCGAGGACAACCT
CGAAGTCGGCCGCTTCTGCACCCAGATCCTGGAGGAACTCGGCCACCAGCCGGTCTGGGCCGAGAATGCCGAGGCGGCCC
TGGTCGAATTGGAACGCACCGAGACGCCGTTCGAGGCGGTGTTTTCGGACGTCGTGATGCCCGGCATGGGCGGCATCGCG
CTCGCCCGCATCCTGCGCGAGCGCTACCCCGATCTGCCGGTGGTCCTTACCTCCGGCTACAGCCACGTCCTGGCGCAGGA
CGACGCGCACGGGTTCGAGCTGCTGAGGAAGCCGTATTCAGCACAGGAGCTTGGGCGGGTGCTGCGGGAGATGGCGGGGC
GGCGGGGGAGGCGGGAGACGGCCTCGCGCTAA

Upstream 100 bases:

>100_bases
CGGTGCCGGTCACGGCGCCGGGGCGGAGCGACGAAGGCCGTTTTGTCCAAACCGTCGCGCTTGTGCCCGCTGGCGGCGTG
CTACATGTGCTCTTGTGAAC

Downstream 100 bases:

>100_bases
CGGCCGAAGCCGGACGCGCGGCCATCCATCCCGAGAGGCTCAATCGAAGCGGACCGCGCCCGGCCGCTGGCGCAGCCTCG
CGCCTCGGCGCTCACTCGCT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MPESLPSPVPSDAESARFRILEPLRAAQEQLARVQDAAGIGVFTLDLREGVLHPSPAFCRLHGLEVRERYALAALAERFP
AEDTAIPSGTSSEEAVYRVRDSRTGASRWIARTLEIERDADGAALRLAGVVRDVTEQRAQGTALAESEQHYRTLFEQMDE
GYSVIEFIDGPHGPLSDYVHVTANRAYAQHAGIENVAGKRLREIVGEEAEGWLALYGDVLRTGRPIRFQRELVATGRYLE
LAAFRIEPPSRRQVAVLFQDITARRRVEHLLHSKAADLEAEVVAQRRDRDRVWTLSPVLKVVATPDGRIEAVNPSWGRTL
GWSPAETVGRYVPDFFAPEERAAAEAALERLAAGASTDLELTCLTKDGGTCRVLWTIVPADGLLYGFGRDITEQRHAEEA
LRQSQKLEAVGQLTGGVAHDFNNLLTIIRSSVEFLRRPDLAPERKRRYLDAVSDTVDRAAKLTGQLLAFARRQALKPETF
DVGERLRSISEMLDSVTGARIRVVTDLPGAPCFVRADASQFETALVNMAVNARDAMDGEGRLTLRLDGAVPMPPIRGHAG
AAGPFVAVSVVDTGTGIASADLGRIFEPFFTTKEVGRGTGLGLSQVIGFAKQSGGDVDVWSRAGEGTTFTLYLPEVAAPL
EAPAPARPRPDADAEAHLRILVVEDNLEVGRFCTQILEELGHQPVWAENAEAALVELERTETPFEAVFSDVVMPGMGGIA
LARILRERYPDLPVVLTSGYSHVLAQDDAHGFELLRKPYSAQELGRVLREMAGRRGRRETASR

Sequences:

>Translated_783_residues
MPESLPSPVPSDAESARFRILEPLRAAQEQLARVQDAAGIGVFTLDLREGVLHPSPAFCRLHGLEVRERYALAALAERFP
AEDTAIPSGTSSEEAVYRVRDSRTGASRWIARTLEIERDADGAALRLAGVVRDVTEQRAQGTALAESEQHYRTLFEQMDE
GYSVIEFIDGPHGPLSDYVHVTANRAYAQHAGIENVAGKRLREIVGEEAEGWLALYGDVLRTGRPIRFQRELVATGRYLE
LAAFRIEPPSRRQVAVLFQDITARRRVEHLLHSKAADLEAEVVAQRRDRDRVWTLSPVLKVVATPDGRIEAVNPSWGRTL
GWSPAETVGRYVPDFFAPEERAAAEAALERLAAGASTDLELTCLTKDGGTCRVLWTIVPADGLLYGFGRDITEQRHAEEA
LRQSQKLEAVGQLTGGVAHDFNNLLTIIRSSVEFLRRPDLAPERKRRYLDAVSDTVDRAAKLTGQLLAFARRQALKPETF
DVGERLRSISEMLDSVTGARIRVVTDLPGAPCFVRADASQFETALVNMAVNARDAMDGEGRLTLRLDGAVPMPPIRGHAG
AAGPFVAVSVVDTGTGIASADLGRIFEPFFTTKEVGRGTGLGLSQVIGFAKQSGGDVDVWSRAGEGTTFTLYLPEVAAPL
EAPAPARPRPDADAEAHLRILVVEDNLEVGRFCTQILEELGHQPVWAENAEAALVELERTETPFEAVFSDVVMPGMGGIA
LARILRERYPDLPVVLTSGYSHVLAQDDAHGFELLRKPYSAQELGRVLREMAGRRGRRETASR
>Mature_782_residues
PESLPSPVPSDAESARFRILEPLRAAQEQLARVQDAAGIGVFTLDLREGVLHPSPAFCRLHGLEVRERYALAALAERFPA
EDTAIPSGTSSEEAVYRVRDSRTGASRWIARTLEIERDADGAALRLAGVVRDVTEQRAQGTALAESEQHYRTLFEQMDEG
YSVIEFIDGPHGPLSDYVHVTANRAYAQHAGIENVAGKRLREIVGEEAEGWLALYGDVLRTGRPIRFQRELVATGRYLEL
AAFRIEPPSRRQVAVLFQDITARRRVEHLLHSKAADLEAEVVAQRRDRDRVWTLSPVLKVVATPDGRIEAVNPSWGRTLG
WSPAETVGRYVPDFFAPEERAAAEAALERLAAGASTDLELTCLTKDGGTCRVLWTIVPADGLLYGFGRDITEQRHAEEAL
RQSQKLEAVGQLTGGVAHDFNNLLTIIRSSVEFLRRPDLAPERKRRYLDAVSDTVDRAAKLTGQLLAFARRQALKPETFD
VGERLRSISEMLDSVTGARIRVVTDLPGAPCFVRADASQFETALVNMAVNARDAMDGEGRLTLRLDGAVPMPPIRGHAGA
AGPFVAVSVVDTGTGIASADLGRIFEPFFTTKEVGRGTGLGLSQVIGFAKQSGGDVDVWSRAGEGTTFTLYLPEVAAPLE
APAPARPRPDADAEAHLRILVVEDNLEVGRFCTQILEELGHQPVWAENAEAALVELERTETPFEAVFSDVVMPGMGGIAL
ARILRERYPDLPVVLTSGYSHVLAQDDAHGFELLRKPYSAQELGRVLREMAGRRGRRETASR

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=339, Percent_Identity=28.9085545722714, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1790436, Length=256, Percent_Identity=27.34375, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI87081816, Length=394, Percent_Identity=28.6802030456853, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI48994928, Length=390, Percent_Identity=28.4615384615385, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1788713, Length=431, Percent_Identity=22.969837587007, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=25.6704980842912, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 85751; Mature: 85620

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPESLPSPVPSDAESARFRILEPLRAAQEQLARVQDAAGIGVFTLDLREGVLHPSPAFCR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCCCCCCHHHE
LHGLEVRERYALAALAERFPAEDTAIPSGTSSEEAVYRVRDSRTGASRWIARTLEIERDA
EECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCC
DGAALRLAGVVRDVTEQRAQGTALAESEQHYRTLFEQMDEGYSVIEFIDGPHGPLSDYVH
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEE
VTANRAYAQHAGIENVAGKRLREIVGEEAEGWLALYGDVLRTGRPIRFQRELVATGRYLE
EECCHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCEEE
LAAFRIEPPSRRQVAVLFQDITARRRVEHLLHSKAADLEAEVVAQRRDRDRVWTLSPVLK
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHHHH
VVATPDGRIEAVNPSWGRTLGWSPAETVGRYVPDFFAPEERAAAEAALERLAAGASTDLE
HHCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEE
LTCLTKDGGTCRVLWTIVPADGLLYGFGRDITEQRHAEEALRQSQKLEAVGQLTGGVAHD
EEEEECCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
FNNLLTIIRSSVEFLRRPDLAPERKRRYLDAVSDTVDRAAKLTGQLLAFARRQALKPETF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DVGERLRSISEMLDSVTGARIRVVTDLPGAPCFVRADASQFETALVNMAVNARDAMDGEG
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCC
RLTLRLDGAVPMPPIRGHAGAAGPFVAVSVVDTGTGIASADLGRIFEPFFTTKEVGRGTG
EEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
LGLSQVIGFAKQSGGDVDVWSRAGEGTTFTLYLPEVAAPLEAPAPARPRPDADAEAHLRI
CCHHHHHHHHHHCCCCEEHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
LVVEDNLEVGRFCTQILEELGHQPVWAENAEAALVELERTETPFEAVFSDVVMPGMGGIA
EEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHH
LARILRERYPDLPVVLTSGYSHVLAQDDAHGFELLRKPYSAQELGRVLREMAGRRGRRET
HHHHHHHHCCCCCEEEECCCCHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
ASR
CCC
>Mature Secondary Structure 
PESLPSPVPSDAESARFRILEPLRAAQEQLARVQDAAGIGVFTLDLREGVLHPSPAFCR
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCCCCCCHHHE
LHGLEVRERYALAALAERFPAEDTAIPSGTSSEEAVYRVRDSRTGASRWIARTLEIERDA
EECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCC
DGAALRLAGVVRDVTEQRAQGTALAESEQHYRTLFEQMDEGYSVIEFIDGPHGPLSDYVH
CCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEE
VTANRAYAQHAGIENVAGKRLREIVGEEAEGWLALYGDVLRTGRPIRFQRELVATGRYLE
EECCHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCEEE
LAAFRIEPPSRRQVAVLFQDITARRRVEHLLHSKAADLEAEVVAQRRDRDRVWTLSPVLK
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEHHHHHH
VVATPDGRIEAVNPSWGRTLGWSPAETVGRYVPDFFAPEERAAAEAALERLAAGASTDLE
HHCCCCCCEEEECCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCEE
LTCLTKDGGTCRVLWTIVPADGLLYGFGRDITEQRHAEEALRQSQKLEAVGQLTGGVAHD
EEEEECCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHH
FNNLLTIIRSSVEFLRRPDLAPERKRRYLDAVSDTVDRAAKLTGQLLAFARRQALKPETF
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
DVGERLRSISEMLDSVTGARIRVVTDLPGAPCFVRADASQFETALVNMAVNARDAMDGEG
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCHHHHHHHHHHHHHCCCCCCCCCC
RLTLRLDGAVPMPPIRGHAGAAGPFVAVSVVDTGTGIASADLGRIFEPFFTTKEVGRGTG
EEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
LGLSQVIGFAKQSGGDVDVWSRAGEGTTFTLYLPEVAAPLEAPAPARPRPDADAEAHLRI
CCHHHHHHHHHHCCCCEEHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEE
LVVEDNLEVGRFCTQILEELGHQPVWAENAEAALVELERTETPFEAVFSDVVMPGMGGIA
EEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHH
LARILRERYPDLPVVLTSGYSHVLAQDDAHGFELLRKPYSAQELGRVLREMAGRRGRRET
HHHHHHHHCCCCCEEEECCCCHHHCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
ASR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA