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The map label for this gene is blh [H]

Identifier: 218532052

GI number: 218532052

Start: 4372368

End: 4373261

Strand: Reverse

Name: blh [H]

Synonym: Mchl_4146

Alternate gene names: 218532052

Gene position: 4373261-4372368 (Counterclockwise)

Preceding gene: 218532053

Following gene: 218532051

Centisome position: 75.69

GC content: 68.68

Gene sequence:

>894_bases
ATGACGGAGACGGACGGCCCGCACCCCCTCGTCCGGGGTTTCTACGAGCGGCGAACGGGCAGCATCCAGTACGTGGTCTC
GTGTCCGCGGACGAAGCGCTGCGCCATCGTCGATCCTGTGCTCGACTTCGACGAGAAGTCGGGGGCGACCGCGACGCGCT
GCGCCGACGAGATCCTGGACTACGTGCGCGCGGCCGGGCTCTCGGTCGAATGGATCCTGGATACGCACCCGCATGCCGAC
CACTTCTCGGCCGCTCAATACCTGAAGGAGCGCACCGGGGCCCCGACCGCCATCGGCGAGCGGGTCGCCGAGGTTCAGAG
GCTCTGGAAGGCCCTCTACGGCTTCACGGACCTGCCGACCGAAGGCGCCCAATGGGACCGGACCTTCGCGGAGGGCGACG
TCTTCTCGGTCGGCGAAGTGCCGGCCCGCATCCTGTTCTCGCCCGGCCACACGCTGGCCTCCGTCACCTACGTGATCGGC
GACGCCGCCTTCGTCCATGATACCCTGTTCATGCCGGATTCGGGCACCGCGCGGGCCGACTTCCCCGGCGGTAGCGCCGT
CACGCTCTGGCGCTCGATCCAAGCCATCCTCGCGCTGCCGGACGACACGCGCCTCTTCACCGGGCACGATTACCAGCCGG
GCGGTCGCGAACCGCGCTGGGAAAGCACCGTCGCCGAGCAGAAAGCCGCCAACACCCACATGGTCGCGGCGCGCAGCGAG
GCGGAGTTCGTGCGCATCCGAGAGGCGCGCGACGCCACTCTGCCGATGCCCAAGCTCATCCTGCACGCGTTGCAGGTCAA
TATCCGTGGCGGCCGGCTGCCGGAGCCCGAGGCGAACGGCAGGCGCTATCTCAAATTTCCGCTCAACGCCCTGGAAGGGG
CGGTGTGGGAATGA

Upstream 100 bases:

>100_bases
ACCCGATCCTCGTCGCGCCGCCGCTGACGTTCCACGGAGCCGCCGCCCGGCCGGAGGGCGAGGCCGGCGACTGGTACTTC
CGAACGGGAACCTTGTGACC

Downstream 100 bases:

>100_bases
GCCCGGCGGCCTCATTTCCCGAGGACAAGGCCCGGGAGGTGTCCGACCTCCTGAAGGTGTTCGCCCATCCCGGACGGTTG
CGCCTCCTCAGCCGCTTGTT

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MTETDGPHPLVRGFYERRTGSIQYVVSCPRTKRCAIVDPVLDFDEKSGATATRCADEILDYVRAAGLSVEWILDTHPHAD
HFSAAQYLKERTGAPTAIGERVAEVQRLWKALYGFTDLPTEGAQWDRTFAEGDVFSVGEVPARILFSPGHTLASVTYVIG
DAAFVHDTLFMPDSGTARADFPGGSAVTLWRSIQAILALPDDTRLFTGHDYQPGGREPRWESTVAEQKAANTHMVAARSE
AEFVRIREARDATLPMPKLILHALQVNIRGGRLPEPEANGRRYLKFPLNALEGAVWE

Sequences:

>Translated_297_residues
MTETDGPHPLVRGFYERRTGSIQYVVSCPRTKRCAIVDPVLDFDEKSGATATRCADEILDYVRAAGLSVEWILDTHPHAD
HFSAAQYLKERTGAPTAIGERVAEVQRLWKALYGFTDLPTEGAQWDRTFAEGDVFSVGEVPARILFSPGHTLASVTYVIG
DAAFVHDTLFMPDSGTARADFPGGSAVTLWRSIQAILALPDDTRLFTGHDYQPGGREPRWESTVAEQKAANTHMVAARSE
AEFVRIREARDATLPMPKLILHALQVNIRGGRLPEPEANGRRYLKFPLNALEGAVWE
>Mature_296_residues
TETDGPHPLVRGFYERRTGSIQYVVSCPRTKRCAIVDPVLDFDEKSGATATRCADEILDYVRAAGLSVEWILDTHPHADH
FSAAQYLKERTGAPTAIGERVAEVQRLWKALYGFTDLPTEGAQWDRTFAEGDVFSVGEVPARILFSPGHTLASVTYVIGD
AAFVHDTLFMPDSGTARADFPGGSAVTLWRSIQAILALPDDTRLFTGHDYQPGGREPRWESTVAEQKAANTHMVAARSEA
EFVRIREARDATLPMPKLILHALQVNIRGGRLPEPEANGRRYLKFPLNALEGAVWE

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=265, Percent_Identity=28.6792452830189, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1787158, Length=188, Percent_Identity=31.3829787234043, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538952, Length=267, Percent_Identity=27.3408239700375, Blast_Score=94, Evalue=6e-20,
Organism=Drosophila melanogaster, GI221330176, Length=268, Percent_Identity=28.7313432835821, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 32832; Mature: 32701

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTETDGPHPLVRGFYERRTGSIQYVVSCPRTKRCAIVDPVLDFDEKSGATATRCADEILD
CCCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEECHHHCCCCCCCCHHHHHHHHHHH
YVRAAGLSVEWILDTHPHADHFSAAQYLKERTGAPTAIGERVAEVQRLWKALYGFTDLPT
HHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
EGAQWDRTFAEGDVFSVGEVPARILFSPGHTLASVTYVIGDAAFVHDTLFMPDSGTARAD
CCCCCCCHHCCCCCEECCCCCEEEEECCCCHHHHHHHHHHCHHHHHHEEECCCCCCCCCC
FPGGSAVTLWRSIQAILALPDDTRLFTGHDYQPGGREPRWESTVAEQKAANTHMVAARSE
CCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCC
AEFVRIREARDATLPMPKLILHALQVNIRGGRLPEPEANGRRYLKFPLNALEGAVWE
HHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCEEEEECHHHHCCCCCC
>Mature Secondary Structure 
TETDGPHPLVRGFYERRTGSIQYVVSCPRTKRCAIVDPVLDFDEKSGATATRCADEILD
CCCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCEEECHHHCCCCCCCCHHHHHHHHHHH
YVRAAGLSVEWILDTHPHADHFSAAQYLKERTGAPTAIGERVAEVQRLWKALYGFTDLPT
HHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
EGAQWDRTFAEGDVFSVGEVPARILFSPGHTLASVTYVIGDAAFVHDTLFMPDSGTARAD
CCCCCCCHHCCCCCEECCCCCEEEEECCCCHHHHHHHHHHCHHHHHHEEECCCCCCCCCC
FPGGSAVTLWRSIQAILALPDDTRLFTGHDYQPGGREPRWESTVAEQKAANTHMVAARSE
CCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCC
AEFVRIREARDATLPMPKLILHALQVNIRGGRLPEPEANGRRYLKFPLNALEGAVWE
HHHHHHHHHCCCCCCHHHHHHHHHHHEECCCCCCCCCCCCCEEEEECHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]