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The map label for this gene is 218531536

Identifier: 218531536

GI number: 218531536

Start: 3797835

End: 3798899

Strand: Reverse

Name: 218531536

Synonym: Mchl_3604

Alternate gene names: NA

Gene position: 3798899-3797835 (Counterclockwise)

Preceding gene: 218531539

Following gene: 218531531

Centisome position: 65.75

GC content: 69.77

Gene sequence:

>1065_bases
ATGGAGCCCGGCGACGACTGGCAACTGACGGAGCGGGTTCGCGCCAGCGTCCGTTCCGGCAAGGGCGATCCCTTCGCGGC
GGCCGTGCGGGCCACGCGCATGGCGATGATCATCACGGACCCGCGCCGGCTCGACAATCCGATCATCTATGCCAACGACG
CGTTCCTGCGGCTCACCGGGTACACGCGGCTGGAGGTGACCGGCCGCAATTGCCGCTTCCTGCAGGGGCCCGGCACCGAT
TTCGACGCGGTGGCGCGGATCCGTGCCGCGATCGATGCCGAGCGGGACGTGCATGAAGAGCTTCTGAACTACCGCAAGGA
CGGTTCGACCTTCCACAACGCGCTGTATATCAGCCCCGTCCACGACGAGGACGGCACGCTGCTGTTCTACTTCGCCTCGC
AGTTCGACGTGAGCGACCGCCACGCGCTCGCGGCCGAGCGCGACCGGACGCAGGCAGCCCTCGACGCGAACGCCCTGCTG
CTGCGCGAGATCGGACATCGCGCCCGCAACGATCTCCAGATGATCTCGGCCATGCTGACGCTTCAGAGCGGCAACAGCGC
CGATCCGGCGGTTCGCGCGGCGCTCGGCGAGGCGATCGGGCGCATCGATGCGCTCAGCACGCTCTACCGCCAGTCCGCCC
CGCCGGAAGAGAGTGCGAGCCACGATCTCAGCGATCTCGTCCGCGAGATCGCCGAGACCCTGGTCGAGGCCTCGGGCCGG
CGCGACATCGCGCTTGCGCTCGATCTCGCGCCGCTCCGCGTCCGGCCCGAGGCGGCGGGACCGCTCGCGCTGATCGTCAA
CGAGGTCGTCTCCAACGCCGTGCGCCACGCCTTCCCGTCCCAGGCCGGACGGCTGACCCTTCGCATCGCCCGGGATGGGG
CGGATGTCACGGTGGCGGTGGAGGATGACGGGATCGGTCCGAGCGCCACGGGCGACGGGAGCTTCGAGGCGACGCTGATC
GATGTTCTGAGCCGGCAGGTCGGCGGGACGATCCGCGTCCGACCACGCGGTCCGGCGGGTACCGCCGTCGAACTCCGCTT
TCCGGCCGATCGCATCGGGGTCTAA

Upstream 100 bases:

>100_bases
ATATGGTCATCGCCGTCTGCTTTGGCGACAGGGTCAGGTGAGGCCGCGCCCTCGGCGGCTTCGGCCGTGCCATTCGCACC
TGGGGAGCGATCGGGAACAG

Downstream 100 bases:

>100_bases
TCCCCCACTGCTCAGACGTCAGTGCCGGTCGTCGGCGGCCGGCGGCAGGGGCATGACCTCGATGCCTTCCTCGACCAGCG
CCCGCGCTTCCTGCGGGCTG

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MEPGDDWQLTERVRASVRSGKGDPFAAAVRATRMAMIITDPRRLDNPIIYANDAFLRLTGYTRLEVTGRNCRFLQGPGTD
FDAVARIRAAIDAERDVHEELLNYRKDGSTFHNALYISPVHDEDGTLLFYFASQFDVSDRHALAAERDRTQAALDANALL
LREIGHRARNDLQMISAMLTLQSGNSADPAVRAALGEAIGRIDALSTLYRQSAPPEESASHDLSDLVREIAETLVEASGR
RDIALALDLAPLRVRPEAAGPLALIVNEVVSNAVRHAFPSQAGRLTLRIARDGADVTVAVEDDGIGPSATGDGSFEATLI
DVLSRQVGGTIRVRPRGPAGTAVELRFPADRIGV

Sequences:

>Translated_354_residues
MEPGDDWQLTERVRASVRSGKGDPFAAAVRATRMAMIITDPRRLDNPIIYANDAFLRLTGYTRLEVTGRNCRFLQGPGTD
FDAVARIRAAIDAERDVHEELLNYRKDGSTFHNALYISPVHDEDGTLLFYFASQFDVSDRHALAAERDRTQAALDANALL
LREIGHRARNDLQMISAMLTLQSGNSADPAVRAALGEAIGRIDALSTLYRQSAPPEESASHDLSDLVREIAETLVEASGR
RDIALALDLAPLRVRPEAAGPLALIVNEVVSNAVRHAFPSQAGRLTLRIARDGADVTVAVEDDGIGPSATGDGSFEATLI
DVLSRQVGGTIRVRPRGPAGTAVELRFPADRIGV
>Mature_354_residues
MEPGDDWQLTERVRASVRSGKGDPFAAAVRATRMAMIITDPRRLDNPIIYANDAFLRLTGYTRLEVTGRNCRFLQGPGTD
FDAVARIRAAIDAERDVHEELLNYRKDGSTFHNALYISPVHDEDGTLLFYFASQFDVSDRHALAAERDRTQAALDANALL
LREIGHRARNDLQMISAMLTLQSGNSADPAVRAALGEAIGRIDALSTLYRQSAPPEESASHDLSDLVREIAETLVEASGR
RDIALALDLAPLRVRPEAAGPLALIVNEVVSNAVRHAFPSQAGRLTLRIARDGADVTVAVEDDGIGPSATGDGSFEATLI
DVLSRQVGGTIRVRPRGPAGTAVELRFPADRIGV

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI6912446, Length=95, Percent_Identity=37.8947368421053, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI27886651, Length=126, Percent_Identity=32.5396825396825, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI13540549, Length=126, Percent_Identity=32.5396825396825, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI38569493, Length=95, Percent_Identity=36.8421052631579, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38339; Mature: 38339

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS50112 PAS ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPGDDWQLTERVRASVRSGKGDPFAAAVRATRMAMIITDPRRLDNPIIYANDAFLRLTG
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEEECCHHCCCCEEEECCCEEEEEC
YTRLEVTGRNCRFLQGPGTDFDAVARIRAAIDAERDVHEELLNYRKDGSTFHNALYISPV
CEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEEE
HDEDGTLLFYFASQFDVSDRHALAAERDRTQAALDANALLLREIGHRARNDLQMISAMLT
ECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQSGNSADPAVRAALGEAIGRIDALSTLYRQSAPPEESASHDLSDLVREIAETLVEASGR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
RDIALALDLAPLRVRPEAAGPLALIVNEVVSNAVRHAFPSQAGRLTLRIARDGADVTVAV
CCEEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEE
EDDGIGPSATGDGSFEATLIDVLSRQVGGTIRVRPRGPAGTAVELRFPADRIGV
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCHHHHCC
>Mature Secondary Structure
MEPGDDWQLTERVRASVRSGKGDPFAAAVRATRMAMIITDPRRLDNPIIYANDAFLRLTG
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHEEEEEEECCHHCCCCEEEECCCEEEEEC
YTRLEVTGRNCRFLQGPGTDFDAVARIRAAIDAERDVHEELLNYRKDGSTFHNALYISPV
CEEEEEECCCEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEEE
HDEDGTLLFYFASQFDVSDRHALAAERDRTQAALDANALLLREIGHRARNDLQMISAMLT
ECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQSGNSADPAVRAALGEAIGRIDALSTLYRQSAPPEESASHDLSDLVREIAETLVEASGR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCC
RDIALALDLAPLRVRPEAAGPLALIVNEVVSNAVRHAFPSQAGRLTLRIARDGADVTVAV
CCEEEEEEECCCEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEE
EDDGIGPSATGDGSFEATLIDVLSRQVGGTIRVRPRGPAGTAVELRFPADRIGV
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCEEEEECCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA