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The map label for this gene is nrdR

Identifier: 218531425

GI number: 218531425

Start: 3677791

End: 3678348

Strand: Reverse

Name: nrdR

Synonym: Mchl_3493

Alternate gene names: 218531425

Gene position: 3678348-3677791 (Counterclockwise)

Preceding gene: 218531426

Following gene: 218531424

Centisome position: 63.66

GC content: 68.28

Gene sequence:

>558_bases
ATGCGGTGTCCGTTCTGCGGAGGTCCCGACACCCAGGTGAAGGATTCGCGCCCGAGCGAAGATTCCTCGGCGATCCGCCG
CCGCCGTGTCTGCCCGGATTGCGGCGGTCGCTTCACGACCTTCGAGCGGGTGCAGTTGCGCGAACTCGTCGTGCTCAAGC
GCTCGGGCAAACGCGTGCCGTTCGATCGCGACAAGCTCCAGCGCTCGATTGATGTGGCGCTGCGCAAGCGCACGGTTGAT
CCCGAGCGGGTGGAGCGCCTTGTCAGCGGCATCACCCGGCGCCTGGAAAGCGGCGGCGAGGGTGAAGTGACCAGCGAGGC
CATCGGCGAGGCGGTGATGGAGGGCCTGAAGGGGCTCGACGACGTCGCCTATGTCCGTTTCGCCTCGGTCTACAAGAATT
TTCGCGAGGCACAGGACTTCCAGGATCTGCTCGGCACCCTCGGAGAGCGGTTGGACGGCGAAGGCGACCTACCCGAACAG
GGGGACGCTGTGCCCGCCCCTCCTGACGAGGCGGTTGCCGCCCCGCGCCGCGGCCGTCCGGCCCGGAAGCGGGCGTGA

Upstream 100 bases:

>100_bases
TCCGACTCCTAGCAATTGAGCGGCTTCTGGCAATTGAGCAGCGGGTGGGGCAGAGAGGGGCGGCTTTTGAGAGCGTCCGG
GATGAGGTGGTGAGCGCGCG

Downstream 100 bases:

>100_bases
CGGGGCGAGCCGTGGACCTGTCCGAGCAGCAAGCCCTCGACCGGCGCGCCATGCGCCTCGCCCTCGCCCTGGGGCGGCGC
AATCTCGGCCGAACCTGGCC

Product: NrdR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MRCPFCGGPDTQVKDSRPSEDSSAIRRRRVCPDCGGRFTTFERVQLRELVVLKRSGKRVPFDRDKLQRSIDVALRKRTVD
PERVERLVSGITRRLESGGEGEVTSEAIGEAVMEGLKGLDDVAYVRFASVYKNFREAQDFQDLLGTLGERLDGEGDLPEQ
GDAVPAPPDEAVAAPRRGRPARKRA

Sequences:

>Translated_185_residues
MRCPFCGGPDTQVKDSRPSEDSSAIRRRRVCPDCGGRFTTFERVQLRELVVLKRSGKRVPFDRDKLQRSIDVALRKRTVD
PERVERLVSGITRRLESGGEGEVTSEAIGEAVMEGLKGLDDVAYVRFASVYKNFREAQDFQDLLGTLGERLDGEGDLPEQ
GDAVPAPPDEAVAAPRRGRPARKRA
>Mature_185_residues
MRCPFCGGPDTQVKDSRPSEDSSAIRRRRVCPDCGGRFTTFERVQLRELVVLKRSGKRVPFDRDKLQRSIDVALRKRTVD
PERVERLVSGITRRLESGGEGEVTSEAIGEAVMEGLKGLDDVAYVRFASVYKNFREAQDFQDLLGTLGERLDGEGDLPEQ
GDAVPAPPDEAVAAPRRGRPARKRA

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=45.578231292517, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_METC4 (B7KUT4)

Other databases:

- EMBL:   CP001298
- RefSeq:   YP_002422241.1
- GeneID:   7114251
- GenomeReviews:   CP001298_GR
- KEGG:   mch:Mchl_3493
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 20570; Mature: 20570

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCPFCGGPDTQVKDSRPSEDSSAIRRRRVCPDCGGRFTTFERVQLRELVVLKRSGKRVP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FDRDKLQRSIDVALRKRTVDPERVERLVSGITRRLESGGEGEVTSEAIGEAVMEGLKGLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCH
DVAYVRFASVYKNFREAQDFQDLLGTLGERLDGEGDLPEQGDAVPAPPDEAVAAPRRGRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCC
ARKRA
CCCCC
>Mature Secondary Structure
MRCPFCGGPDTQVKDSRPSEDSSAIRRRRVCPDCGGRFTTFERVQLRELVVLKRSGKRVP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
FDRDKLQRSIDVALRKRTVDPERVERLVSGITRRLESGGEGEVTSEAIGEAVMEGLKGLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCH
DVAYVRFASVYKNFREAQDFQDLLGTLGERLDGEGDLPEQGDAVPAPPDEAVAAPRRGRP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCCCC
ARKRA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA