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The map label for this gene is ribD [H]

Identifier: 218531424

GI number: 218531424

Start: 3676664

End: 3677794

Strand: Reverse

Name: ribD [H]

Synonym: Mchl_3492

Alternate gene names: 218531424

Gene position: 3677794-3676664 (Counterclockwise)

Preceding gene: 218531425

Following gene: 218531423

Centisome position: 63.65

GC content: 74.09

Gene sequence:

>1131_bases
GTGACGGGGCGAGCCGTGGACCTGTCCGAGCAGCAAGCCCTCGACCGGCGCGCCATGCGCCTCGCCCTCGCCCTGGGGCG
GCGCAATCTCGGCCGAACCTGGCCGAATCCGAGCGTCGGCGCCGTCGTCGTGGCCGAGGGCCGCATCGTCGGGCAGGCGG
TCACGGCGGTCGGCGGTCGCCCGCACGCGGAGCCGCTGGCGCTCGCCATGGCCGGCGAGGCCGCGCGCGGGGCCACGCTC
TACGTCACCCTCGAGCCCTGCTCGCATCACGGCCGCACGCCGCCCTGCACCGACGCGACCATCGCCGCCGGAATCGCCCG
CGTGGTCACCGCGATCGAGGATCCCGATCCGCGGGTGGCCGGGCGCGGCCATGCGGGTTTGCGCGCGGCCGGGATCACGG
TTGAAACCGGCCTGCTGCGCGAGGAGGCCGCCCGCGATCATCGCGGCCATTTCTCCCGCGTGACGCGCGGGCGCCCGAGC
CTGCATCTCAAGCTCGCCCGGACCCGCGACGGCTTCGCCGCGCCCTCGACCGGTGAGCGCCTGAAGATCACAGGTTCGGT
CGCGGATGGCGCGGTGCATCTGTGGCGGGCGCATGCCGACGCGATCATGGTCGGCATCGGCACGGCTCGCGCCGACGACC
CTTCGCTGACGGTCCGGCTTCCGGGGCTCGCCGAGCGCTCGCCGCTGCGGATCGTGCTCGACTCGACATTGCGCCTCAAC
CCAGCCAGCCACCTCGTGCGCGGGGCCCGCGACCTGCCGACCCTGGTTCTCACCGGGCGCGGCGCTCCGGCCCATGCCCG
GCGGATGCTCGCCTCCTTCGGCGTCGAGATCGCCTTCGTTCCGACCGATGCGGAGGGCCGCATAGACTTACCCGCCGCGC
TGAAAGCGCTGGCGGAGCGCGGCCTGACCCGGATCTGCAGCGAGGGCGGGCCGGCGCTTGCCGACACGCTCGCGGCGCAC
GATCTCATCGATGCCTGCACGCTCATCACCGGCTCCGTCACGCTGGGCGAAGCCGGCGGCTTGCCGGCGCTCGGGGCCAA
CCTCGCCCGCCGTCTCGCCGACGGCTCCCTGAGCGTGGTCGAGACCCGCGATTACGGCCCCGACACGGCGGTCACCTACG
AGAGGATCTGA

Upstream 100 bases:

>100_bases
ACGGCGAAGGCGACCTACCCGAACAGGGGGACGCTGTGCCCGCCCCTCCTGACGAGGCGGTTGCCGCCCCGCGCCGCGGC
CGTCCGGCCCGGAAGCGGGC

Downstream 100 bases:

>100_bases
CATGTTCACCGGACTCGTCAGCGATGTCGGCCGCGTCGTCTCGGTGGAGGGCTCGGAGCGCCTGCGCCGGATCGTGATCG
AGAGCGCCTACGATCCCGCC

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MTGRAVDLSEQQALDRRAMRLALALGRRNLGRTWPNPSVGAVVVAEGRIVGQAVTAVGGRPHAEPLALAMAGEAARGATL
YVTLEPCSHHGRTPPCTDATIAAGIARVVTAIEDPDPRVAGRGHAGLRAAGITVETGLLREEAARDHRGHFSRVTRGRPS
LHLKLARTRDGFAAPSTGERLKITGSVADGAVHLWRAHADAIMVGIGTARADDPSLTVRLPGLAERSPLRIVLDSTLRLN
PASHLVRGARDLPTLVLTGRGAPAHARRMLASFGVEIAFVPTDAEGRIDLPAALKALAERGLTRICSEGGPALADTLAAH
DLIDACTLITGSVTLGEAGGLPALGANLARRLADGSLSVVETRDYGPDTAVTYERI

Sequences:

>Translated_376_residues
MTGRAVDLSEQQALDRRAMRLALALGRRNLGRTWPNPSVGAVVVAEGRIVGQAVTAVGGRPHAEPLALAMAGEAARGATL
YVTLEPCSHHGRTPPCTDATIAAGIARVVTAIEDPDPRVAGRGHAGLRAAGITVETGLLREEAARDHRGHFSRVTRGRPS
LHLKLARTRDGFAAPSTGERLKITGSVADGAVHLWRAHADAIMVGIGTARADDPSLTVRLPGLAERSPLRIVLDSTLRLN
PASHLVRGARDLPTLVLTGRGAPAHARRMLASFGVEIAFVPTDAEGRIDLPAALKALAERGLTRICSEGGPALADTLAAH
DLIDACTLITGSVTLGEAGGLPALGANLARRLADGSLSVVETRDYGPDTAVTYERI
>Mature_375_residues
TGRAVDLSEQQALDRRAMRLALALGRRNLGRTWPNPSVGAVVVAEGRIVGQAVTAVGGRPHAEPLALAMAGEAARGATLY
VTLEPCSHHGRTPPCTDATIAAGIARVVTAIEDPDPRVAGRGHAGLRAAGITVETGLLREEAARDHRGHFSRVTRGRPSL
HLKLARTRDGFAAPSTGERLKITGSVADGAVHLWRAHADAIMVGIGTARADDPSLTVRLPGLAERSPLRIVLDSTLRLNP
ASHLVRGARDLPTLVLTGRGAPAHARRMLASFGVEIAFVPTDAEGRIDLPAALKALAERGLTRICSEGGPALADTLAAHD
LIDACTLITGSVTLGEAGGLPALGANLARRLADGSLSVVETRDYGPDTAVTYERI

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=372, Percent_Identity=40.5913978494624, Blast_Score=228, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39199; Mature: 39068

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGRAVDLSEQQALDRRAMRLALALGRRNLGRTWPNPSVGAVVVAEGRIVGQAVTAVGGR
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEHHHHHHCCCC
PHAEPLALAMAGEAARGATLYVTLEPCSHHGRTPPCTDATIAAGIARVVTAIEDPDPRVA
CCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GRGHAGLRAAGITVETGLLREEAARDHRGHFSRVTRGRPSLHLKLARTRDGFAAPSTGER
CCCCCCEEEECEEEEHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCE
LKITGSVADGAVHLWRAHADAIMVGIGTARADDPSLTVRLPGLAERSPLRIVLDSTLRLN
EEEEECCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCEEEC
PASHLVRGARDLPTLVLTGRGAPAHARRMLASFGVEIAFVPTDAEGRIDLPAALKALAER
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
GLTRICSEGGPALADTLAAHDLIDACTLITGSVTLGEAGGLPALGANLARRLADGSLSVV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCCCEEEE
ETRDYGPDTAVTYERI
EECCCCCCCCEEEECC
>Mature Secondary Structure 
TGRAVDLSEQQALDRRAMRLALALGRRNLGRTWPNPSVGAVVVAEGRIVGQAVTAVGGR
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCEEEHHHHHHCCCC
PHAEPLALAMAGEAARGATLYVTLEPCSHHGRTPPCTDATIAAGIARVVTAIEDPDPRVA
CCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
GRGHAGLRAAGITVETGLLREEAARDHRGHFSRVTRGRPSLHLKLARTRDGFAAPSTGER
CCCCCCEEEECEEEEHHHHHHHHHHHHCCHHHHHHCCCCCEEEEEEECCCCCCCCCCCCE
LKITGSVADGAVHLWRAHADAIMVGIGTARADDPSLTVRLPGLAERSPLRIVLDSTLRLN
EEEEECCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCEEEEECCCEEEC
PASHLVRGARDLPTLVLTGRGAPAHARRMLASFGVEIAFVPTDAEGRIDLPAALKALAER
HHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHHHH
GLTRICSEGGPALADTLAAHDLIDACTLITGSVTLGEAGGLPALGANLARRLADGSLSVV
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCCCEEEE
ETRDYGPDTAVTYERI
EECCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]