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The map label for this gene is thiL [H]

Identifier: 218531416

GI number: 218531416

Start: 3669706

End: 3670683

Strand: Reverse

Name: thiL [H]

Synonym: Mchl_3484

Alternate gene names: 218531416

Gene position: 3670683-3669706 (Counterclockwise)

Preceding gene: 218531417

Following gene: 218531412

Centisome position: 63.53

GC content: 73.93

Gene sequence:

>978_bases
ATGGCGCGCGCGGGCGAGGAGGCGCTGATCGCGCGCTACTTCGCGCCGCTCAGCGGCCCCGGCGCCGAGGGCCTGCGCGA
TGACGCCGCGAGCCTGACGCCGACGCCCGGCCACGACCTCGTGGTGACCACCGACGCCATCGTGGCCGGCGTTCACTACT
TTCCCGACGACCCGCCCGGCTCCATTGCCAGCAAGGCGCTCGGCGTGAACCTGTCGGATCTCGCCGCCAAGGGCGCCACT
CCGCGCGGCTTCCTCCTCACCCTCGCACTGCCGGACGACTGGACCGAAGCTTGGCTCGCGGGTTTCGCCGAGGGTCTCGG
TGAAGCAAGCCGCGCCCATGGCTGCCCGCTTCTGGGCGGTGACACCGTGCGCTCCGGCGGGCCGGCGCTGATCGGCGTGA
CCGCCTTCGGCGAGGTGCCGGCCGGCGCAATCCTGCGGCGGCAGGCGGCCCAAGCCGGCGACCGGCTCTGCGTCAGCGGT
ACCATCGGCGACGCGGCTCTGGGCCTCGCCCTGCGGCTCGCACCCGATCCCGCGCTGGCCTCCCTCCACCGCGATGCGCT
CCTCGATCGCTACCTTCACCCGCGCCCGCGGTTGGCGCTCGCCTCCGTGCTGCGGCGCCACGCCCGCGCGGCCATGGACG
TCTCGGACGGATTGGCGGGCGATCTGACCAAGATGTTCGCCGGCACCGGCCTGACCGCGCGGATCGATGTTCCGGCGGTG
CCACTCTCACCGGCGGCGCAGGCGGCCATCTCCGGCGACGCCAGCCGGCTCGACACGGCCCTGACCGGAGGGGACGATTA
CGAGATCCTCTGCGCGGTGCCGCCCGGTTCCGTGGGCGCGTTCCTGGCCGAGGCCCGGGCCGCCGGGGTGCCCGTAGCCG
AGATCGGCACCGTGGACGCCGGCGACGGACCGCCTCGCTTTCACGACGCGCATGGGCGCGAGATGGGCTTTGCCCGCGCC
TCGTTCAGCCACTTCTGA

Upstream 100 bases:

>100_bases
GCATGGTCAACGCCGTGCTCGACCGGGTCGGCCGCGAGGTGCGCTCCACCGAGTTCGGCATCCCGGCCGCTCCCGGCCCG
GCGAAGAAGGGCTGACCGGA

Downstream 100 bases:

>100_bases
AGCGCCATCTCCGCTTGACGGCCTGAGGCCTGATCGCGGCCGCCGTCGTTGAGAGCAAGGCGAACAATTCGAAGAAGGCG
CCGCGTAAGCGTGCTCCGCC

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MARAGEEALIARYFAPLSGPGAEGLRDDAASLTPTPGHDLVVTTDAIVAGVHYFPDDPPGSIASKALGVNLSDLAAKGAT
PRGFLLTLALPDDWTEAWLAGFAEGLGEASRAHGCPLLGGDTVRSGGPALIGVTAFGEVPAGAILRRQAAQAGDRLCVSG
TIGDAALGLALRLAPDPALASLHRDALLDRYLHPRPRLALASVLRRHARAAMDVSDGLAGDLTKMFAGTGLTARIDVPAV
PLSPAAQAAISGDASRLDTALTGGDDYEILCAVPPGSVGAFLAEARAAGVPVAEIGTVDAGDGPPRFHDAHGREMGFARA
SFSHF

Sequences:

>Translated_325_residues
MARAGEEALIARYFAPLSGPGAEGLRDDAASLTPTPGHDLVVTTDAIVAGVHYFPDDPPGSIASKALGVNLSDLAAKGAT
PRGFLLTLALPDDWTEAWLAGFAEGLGEASRAHGCPLLGGDTVRSGGPALIGVTAFGEVPAGAILRRQAAQAGDRLCVSG
TIGDAALGLALRLAPDPALASLHRDALLDRYLHPRPRLALASVLRRHARAAMDVSDGLAGDLTKMFAGTGLTARIDVPAV
PLSPAAQAAISGDASRLDTALTGGDDYEILCAVPPGSVGAFLAEARAAGVPVAEIGTVDAGDGPPRFHDAHGREMGFARA
SFSHF
>Mature_324_residues
ARAGEEALIARYFAPLSGPGAEGLRDDAASLTPTPGHDLVVTTDAIVAGVHYFPDDPPGSIASKALGVNLSDLAAKGATP
RGFLLTLALPDDWTEAWLAGFAEGLGEASRAHGCPLLGGDTVRSGGPALIGVTAFGEVPAGAILRRQAAQAGDRLCVSGT
IGDAALGLALRLAPDPALASLHRDALLDRYLHPRPRLALASVLRRHARAAMDVSDGLAGDLTKMFAGTGLTARIDVPAVP
LSPAAQAAISGDASRLDTALTGGDDYEILCAVPPGSVGAFLAEARAAGVPVAEIGTVDAGDGPPRFHDAHGREMGFARAS
FSHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=322, Percent_Identity=38.1987577639752, Blast_Score=171, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 32995; Mature: 32863

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARAGEEALIARYFAPLSGPGAEGLRDDAASLTPTPGHDLVVTTDAIVAGVHYFPDDPPG
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCCCCCH
SIASKALGVNLSDLAAKGATPRGFLLTLALPDDWTEAWLAGFAEGLGEASRAHGCPLLGG
HHHHHHHCCCHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
DTVRSGGPALIGVTAFGEVPAGAILRRQAAQAGDRLCVSGTIGDAALGLALRLAPDPALA
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHCEEEEECCCHHHH
SLHRDALLDRYLHPRPRLALASVLRRHARAAMDVSDGLAGDLTKMFAGTGLTARIDVPAV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEECCCCC
PLSPAAQAAISGDASRLDTALTGGDDYEILCAVPPGSVGAFLAEARAAGVPVAEIGTVDA
CCCHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHCCCCCC
GDGPPRFHDAHGREMGFARASFSHF
CCCCCCCCCCCCCHHCHHHHHCCCC
>Mature Secondary Structure 
ARAGEEALIARYFAPLSGPGAEGLRDDAASLTPTPGHDLVVTTDAIVAGVHYFPDDPPG
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHCCCCCCCH
SIASKALGVNLSDLAAKGATPRGFLLTLALPDDWTEAWLAGFAEGLGEASRAHGCPLLGG
HHHHHHHCCCHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
DTVRSGGPALIGVTAFGEVPAGAILRRQAAQAGDRLCVSGTIGDAALGLALRLAPDPALA
CCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHCEEEEECCCHHHH
SLHRDALLDRYLHPRPRLALASVLRRHARAAMDVSDGLAGDLTKMFAGTGLTARIDVPAV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEECCCCC
PLSPAAQAAISGDASRLDTALTGGDDYEILCAVPPGSVGAFLAEARAAGVPVAEIGTVDA
CCCHHHHHHHCCCHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHCCCCHHHCCCCCC
GDGPPRFHDAHGREMGFARASFSHF
CCCCCCCCCCCCCHHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]