Click here to switch to the map view.

The map label for this gene is resD [H]

Identifier: 218236073

GI number: 218236073

Start: 1311251

End: 1311922

Strand: Direct

Name: resD [H]

Synonym: BCB4264_A1351

Alternate gene names: 218236073

Gene position: 1311251-1311922 (Clockwise)

Preceding gene: 218234141

Following gene: 218234975

Centisome position: 24.2

GC content: 37.35

Gene sequence:

>672_bases
ATGAATAAATATAGAGTGCTAGTTGTAGATGATGAAAGTGATATGAGACAGCTTGTTGGAATGTATTTGGATAACTTTGG
ATATGAGTGGGGAGAAGCTGAGAATGGAAAAGAGGCTCTTAAAAAACTAGAAACGGATCATTATGATTTCGTTGTATTAG
ATATAATGATGCCAGAAATGGATGGACTTTCAGTTTGTAAAGAAATTAGAAAAACGTCAGATGTGCCGATTATATTTTTA
ACGGCAAAAGGTGAAGAGTGGAATAGGGTGAACGGCTTACGTATGGGAGCAGATGACTATATTGTAAAACCGTTTAGTCC
TGGTGAATTGGTTGCCCGTATGGAAGCTGTGCTAAGAAGATATACAAAGCAAGAACAGCAAGAAGAGATTCAATTTGGAC
CAATTCTTATCAATGAAAAAAGTAGACGAATAGAGGCGGATGGTGAGTCGATTTCTCTTACTGTAAAAGAGTTTGATTTA
TTATATTTTCTTTGCCAACATACAGGACAAGTATTTAGCCGGGAGCAATTACTTGAAAAGGTATGGGGATATGATTATGC
CGGAAGTACAAGAACGGTAGATACGCATGTGAAAACGATGCGCTTGAAGCTTGGAGAAAGTGGAAACTACATTCAAACTG
TTTGGGGTGTAGGCTATAAATTTGAGGTGTAA

Upstream 100 bases:

>100_bases
GATGAAGTGTGCGTTATAGATATGAAGAATTTGAAAATAAAACAAACAATTAAAGTCGGAAAAGGACCATTTCAACTCAT
AGAGAGGGAAGGGAAGGACA

Downstream 100 bases:

>100_bases
CGTATGTTTACGATGGTACAAAAACTTTGGCTTACAGTAGTATGTGCAGTATGTGTAACAGTGTCCTTTCTTTATTTCGT
ATCTTTATACTCGTATGAAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MNKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETDHYDFVVLDIMMPEMDGLSVCKEIRKTSDVPIIFL
TAKGEEWNRVNGLRMGADDYIVKPFSPGELVARMEAVLRRYTKQEQQEEIQFGPILINEKSRRIEADGESISLTVKEFDL
LYFLCQHTGQVFSREQLLEKVWGYDYAGSTRTVDTHVKTMRLKLGESGNYIQTVWGVGYKFEV

Sequences:

>Translated_223_residues
MNKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETDHYDFVVLDIMMPEMDGLSVCKEIRKTSDVPIIFL
TAKGEEWNRVNGLRMGADDYIVKPFSPGELVARMEAVLRRYTKQEQQEEIQFGPILINEKSRRIEADGESISLTVKEFDL
LYFLCQHTGQVFSREQLLEKVWGYDYAGSTRTVDTHVKTMRLKLGESGNYIQTVWGVGYKFEV
>Mature_223_residues
MNKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETDHYDFVVLDIMMPEMDGLSVCKEIRKTSDVPIIFL
TAKGEEWNRVNGLRMGADDYIVKPFSPGELVARMEAVLRRYTKQEQQEEIQFGPILINEKSRRIEADGESISLTVKEFDL
LYFLCQHTGQVFSREQLLEKVWGYDYAGSTRTVDTHVKTMRLKLGESGNYIQTVWGVGYKFEV

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=41.4414414414414, Blast_Score=177, Evalue=4e-46,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=40.7079646017699, Blast_Score=173, Evalue=6e-45,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=39.9122807017544, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=36.036036036036, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=38.4279475982533, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=33.7899543378995, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=34.8623853211009, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=35.7798165137615, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=35.3982300884956, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=32.7272727272727, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=31.8965517241379, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=31.5315315315315, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI145693140, Length=230, Percent_Identity=30.4347826086957, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=30.0448430493274, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788550, Length=146, Percent_Identity=36.3013698630137, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=36.0294117647059, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788191, Length=120, Percent_Identity=37.5, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=105, Percent_Identity=35.2380952380952, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI145693157, Length=102, Percent_Identity=34.3137254901961, Blast_Score=64, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=121, Percent_Identity=30.5785123966942, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25837; Mature: 25837

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETDHYDFVVLDIMMPEM
CCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCC
DGLSVCKEIRKTSDVPIIFLTAKGEEWNRVNGLRMGADDYIVKPFSPGELVARMEAVLRR
CHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCCEEECCCCCHHHHHHHHHHHHH
YTKQEQQEEIQFGPILINEKSRRIEADGESISLTVKEFDLLYFLCQHTGQVFSREQLLEK
HHHHHHHHHHCCCCEEECCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VWGYDYAGSTRTVDTHVKTMRLKLGESGNYIQTVWGVGYKFEV
HCCCCCCCCCEEHHHHHEEEEEEECCCCCEEEHEECCCEEECC
>Mature Secondary Structure
MNKYRVLVVDDESDMRQLVGMYLDNFGYEWGEAENGKEALKKLETDHYDFVVLDIMMPEM
CCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCC
DGLSVCKEIRKTSDVPIIFLTAKGEEWNRVNGLRMGADDYIVKPFSPGELVARMEAVLRR
CHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCCEEECCCCCHHHHHHHHHHHHH
YTKQEQQEEIQFGPILINEKSRRIEADGESISLTVKEFDLLYFLCQHTGQVFSREQLLEK
HHHHHHHHHHCCCCEEECCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
VWGYDYAGSTRTVDTHVKTMRLKLGESGNYIQTVWGVGYKFEV
HCCCCCCCCCEEHHHHHEEEEEEECCCCCEEEHEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]