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The map label for this gene is resE [H]

Identifier: 218234975

GI number: 218234975

Start: 1311926

End: 1313326

Strand: Direct

Name: resE [H]

Synonym: BCB4264_A1352

Alternate gene names: 218234975

Gene position: 1311926-1313326 (Clockwise)

Preceding gene: 218236073

Following gene: 218231497

Centisome position: 24.21

GC content: 34.83

Gene sequence:

>1401_bases
ATGTTTACGATGGTACAAAAACTTTGGCTTACAGTAGTATGTGCAGTATGTGTAACAGTGTCCTTTCTTTATTTCGTATC
TTTATACTCGTATGAAAAATTATACGTTGATAATTTAAAAGCTTCGTTAGTAATGGAAGGAAAAAGTCTTGCTGCTCAAT
ATGATAAGCGTGAAGGAATATCAACTTTTGAAGAGAAAGTAAGATCGTTTGATCAAATATCTAGTTCAGACGTTATTTTC
GTGTCTAATCCGCGTGATTTAAGCGCATGTTTGCCTTTTGATGTGCATCATCATTCTCTTATAAGTGAAGGAGATAGGCA
AACGCTATTAGACGGGAAAACTGTGACAAAAATAGGATATGAAGAACATTTTGACCGTAATATTATGGGGGTTGTCATCC
CTGTATTGGAAAATAAAAAATTAGTCGGAATTGTCTATTCGTATATTCCTTTAAAAAGTATAAAAGATTTAATCTATGAT
ATGGGTCTTATTTTAGCACCGTTAGCAATTGCTATGATTTTAATTACGATATGGGTTGGAAGGAAAATTATAATTGCAAT
TACGAAGCCACTTTCGCAAATGGAGCGGGTTGCAAATCATTTGGCTACGGGAGATTTTTCGGAGCGGATTACAGTTTCTT
CAGAGGATGAAATTGGACGATTAGGAAAAGCATTTAATAAAATGGCAAATTCATTAGAAACAGAAGATGTAAAGCGTAAG
GAATTTTTAGCAAATGTTTCGCATGAACTTAGAACACCACTTAGTTATATAAAAGGGTATAGCGAGGCTATTTTAGATGG
TGTTGCAAAGGGACCGCAGCAGGAAAAAGTAACGCAGCTAATTCATAAAGAAGCAGGTCGTATGCAGCGTCTCGTTCATG
ACTTGTTAGACTTAGCACAATTAGAAGGTGAGCACTTTCCGTTAAAGAAGCAACCTATCGTTTTTTCACAGCTGATTGAA
GACGTATTAGATACGTATGAGATTAAGTTTATAGAAAAGGAAATTCATATTTCAACTAATTTAAATCCAGAGGTCATTGT
CATGATTGATGAAGATCGTATGCAACAAGTGCTTCATAATGTGTTAGATAATGCGATACGGTATACAAATCAAAAAGGAA
ATATCGTTATAACTTTAGAGCAAATCGATGATTACTGTGAATTAAAAATAAAAGATACAGGAATTGGTATTGATATAGAA
CATTTGGAGAATCTTGGAGAACGCTTTTACCGAGTTGATAAAGCGAGAAGTCGTCAACACGGTGGAACAGGTTTAGGCCT
TGCTATTGTGAAACAAATTGTTCATATACATGGTGGACAGTGGAAAATTGAAAGTGAAAAAGATAAGGGAACAACGGTTA
TTATTAAACTGAATGTACAGGATGAGGGGAGCATGTTCTAA

Upstream 100 bases:

>100_bases
GGTAGATACGCATGTGAAAACGATGCGCTTGAAGCTTGGAGAAAGTGGAAACTACATTCAAACTGTTTGGGGTGTAGGCT
ATAAATTTGAGGTGTAACGT

Downstream 100 bases:

>100_bases
TTTTTAGGACATGTTCTTTATATTGAAGAAAATATTTATCCCGCTATTCGCCGGGCAGTAAGACCCTCACCTCAAAATTC
AACGGAAGCAAAGAAGTTAG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MFTMVQKLWLTVVCAVCVTVSFLYFVSLYSYEKLYVDNLKASLVMEGKSLAAQYDKREGISTFEEKVRSFDQISSSDVIF
VSNPRDLSACLPFDVHHHSLISEGDRQTLLDGKTVTKIGYEEHFDRNIMGVVIPVLENKKLVGIVYSYIPLKSIKDLIYD
MGLILAPLAIAMILITIWVGRKIIIAITKPLSQMERVANHLATGDFSERITVSSEDEIGRLGKAFNKMANSLETEDVKRK
EFLANVSHELRTPLSYIKGYSEAILDGVAKGPQQEKVTQLIHKEAGRMQRLVHDLLDLAQLEGEHFPLKKQPIVFSQLIE
DVLDTYEIKFIEKEIHISTNLNPEVIVMIDEDRMQQVLHNVLDNAIRYTNQKGNIVITLEQIDDYCELKIKDTGIGIDIE
HLENLGERFYRVDKARSRQHGGTGLGLAIVKQIVHIHGGQWKIESEKDKGTTVIIKLNVQDEGSMF

Sequences:

>Translated_466_residues
MFTMVQKLWLTVVCAVCVTVSFLYFVSLYSYEKLYVDNLKASLVMEGKSLAAQYDKREGISTFEEKVRSFDQISSSDVIF
VSNPRDLSACLPFDVHHHSLISEGDRQTLLDGKTVTKIGYEEHFDRNIMGVVIPVLENKKLVGIVYSYIPLKSIKDLIYD
MGLILAPLAIAMILITIWVGRKIIIAITKPLSQMERVANHLATGDFSERITVSSEDEIGRLGKAFNKMANSLETEDVKRK
EFLANVSHELRTPLSYIKGYSEAILDGVAKGPQQEKVTQLIHKEAGRMQRLVHDLLDLAQLEGEHFPLKKQPIVFSQLIE
DVLDTYEIKFIEKEIHISTNLNPEVIVMIDEDRMQQVLHNVLDNAIRYTNQKGNIVITLEQIDDYCELKIKDTGIGIDIE
HLENLGERFYRVDKARSRQHGGTGLGLAIVKQIVHIHGGQWKIESEKDKGTTVIIKLNVQDEGSMF
>Mature_466_residues
MFTMVQKLWLTVVCAVCVTVSFLYFVSLYSYEKLYVDNLKASLVMEGKSLAAQYDKREGISTFEEKVRSFDQISSSDVIF
VSNPRDLSACLPFDVHHHSLISEGDRQTLLDGKTVTKIGYEEHFDRNIMGVVIPVLENKKLVGIVYSYIPLKSIKDLIYD
MGLILAPLAIAMILITIWVGRKIIIAITKPLSQMERVANHLATGDFSERITVSSEDEIGRLGKAFNKMANSLETEDVKRK
EFLANVSHELRTPLSYIKGYSEAILDGVAKGPQQEKVTQLIHKEAGRMQRLVHDLLDLAQLEGEHFPLKKQPIVFSQLIE
DVLDTYEIKFIEKEIHISTNLNPEVIVMIDEDRMQQVLHNVLDNAIRYTNQKGNIVITLEQIDDYCELKIKDTGIGIDIE
HLENLGERFYRVDKARSRQHGGTGLGLAIVKQIVHIHGGQWKIESEKDKGTTVIIKLNVQDEGSMF

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=275, Percent_Identity=34.5454545454545, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786600, Length=213, Percent_Identity=36.150234741784, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1789149, Length=368, Percent_Identity=26.3586956521739, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1786783, Length=365, Percent_Identity=26.8493150684932, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI145693157, Length=243, Percent_Identity=29.2181069958848, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1790346, Length=271, Percent_Identity=28.4132841328413, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI1790861, Length=344, Percent_Identity=25.2906976744186, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI48994928, Length=239, Percent_Identity=28.4518828451883, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=33.1914893617021, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI87081816, Length=335, Percent_Identity=25.0746268656716, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788279, Length=252, Percent_Identity=30.5555555555556, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1787894, Length=263, Percent_Identity=28.1368821292776, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786912, Length=474, Percent_Identity=24.2616033755274, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788713, Length=246, Percent_Identity=29.2682926829268, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790551, Length=297, Percent_Identity=27.9461279461279, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788549, Length=226, Percent_Identity=26.1061946902655, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI87082128, Length=299, Percent_Identity=23.0769230769231, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789403, Length=278, Percent_Identity=27.6978417266187, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789808, Length=291, Percent_Identity=26.8041237113402, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787374, Length=278, Percent_Identity=22.3021582733813, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52833; Mature: 52833

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTMVQKLWLTVVCAVCVTVSFLYFVSLYSYEKLYVDNLKASLVMEGKSLAAQYDKREGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCHHHHHHHHHHCCH
STFEEKVRSFDQISSSDVIFVSNPRDLSACLPFDVHHHSLISEGDRQTLLDGKTVTKIGY
HHHHHHHHHHHCCCCCCEEEEECCCCCHHCCCCCCHHHHHHCCCCCHHHCCCCHHEECCC
EEHFDRNIMGVVIPVLENKKLVGIVYSYIPLKSIKDLIYDMGLILAPLAIAMILITIWVG
HHHCCCCCCEEEEEHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RKIIIAITKPLSQMERVANHLATGDFSERITVSSEDEIGRLGKAFNKMANSLETEDVKRK
CEEEEEECCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCHHHHHHH
EFLANVSHELRTPLSYIKGYSEAILDGVAKGPQQEKVTQLIHKEAGRMQRLVHDLLDLAQ
HHHHHHHHHHHCHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEGEHFPLKKQPIVFSQLIEDVLDTYEIKFIEKEIHISTNLNPEVIVMIDEDRMQQVLHN
HCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEEECHHHHHHHHHH
VLDNAIRYTNQKGNIVITLEQIDDYCELKIKDTGIGIDIEHLENLGERFYRVDKARSRQH
HHHHHHHHCCCCCCEEEEEHHCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCC
GGTGLGLAIVKQIVHIHGGQWKIESEKDKGTTVIIKLNVQDEGSMF
CCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MFTMVQKLWLTVVCAVCVTVSFLYFVSLYSYEKLYVDNLKASLVMEGKSLAAQYDKREGI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEECCHHHHHHHHHHCCH
STFEEKVRSFDQISSSDVIFVSNPRDLSACLPFDVHHHSLISEGDRQTLLDGKTVTKIGY
HHHHHHHHHHHCCCCCCEEEEECCCCCHHCCCCCCHHHHHHCCCCCHHHCCCCHHEECCC
EEHFDRNIMGVVIPVLENKKLVGIVYSYIPLKSIKDLIYDMGLILAPLAIAMILITIWVG
HHHCCCCCCEEEEEHHCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RKIIIAITKPLSQMERVANHLATGDFSERITVSSEDEIGRLGKAFNKMANSLETEDVKRK
CEEEEEECCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCHHHHHHH
EFLANVSHELRTPLSYIKGYSEAILDGVAKGPQQEKVTQLIHKEAGRMQRLVHDLLDLAQ
HHHHHHHHHHHCHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEGEHFPLKKQPIVFSQLIEDVLDTYEIKFIEKEIHISTNLNPEVIVMIDEDRMQQVLHN
HCCCCCCCCCCCHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEEECHHHHHHHHHH
VLDNAIRYTNQKGNIVITLEQIDDYCELKIKDTGIGIDIEHLENLGERFYRVDKARSRQH
HHHHHHHHCCCCCCEEEEEHHCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHCC
GGTGLGLAIVKQIVHIHGGQWKIESEKDKGTTVIIKLNVQDEGSMF
CCCCHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]