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The map label for this gene is rocE [H]

Identifier: 218236026

GI number: 218236026

Start: 670207

End: 671634

Strand: Direct

Name: rocE [H]

Synonym: BCB4264_A0679

Alternate gene names: 218236026

Gene position: 670207-671634 (Clockwise)

Preceding gene: 218233063

Following gene: 218235416

Centisome position: 12.37

GC content: 37.18

Gene sequence:

>1428_bases
ATGCAGCAACCAACGAATGAGAAATTACATCGTACGATGAAGAGTAGACATTTATTTATGATCGCACTAGGTGGTGTAAT
CGGAACTGGTTTTTTCTTAGGTTCAGGTTACACCATTAATCAGGCTGGACCAGGGGGAGCCATCCTTTCATATTTAGTAG
GCGGATTTATTATGTATTTAACAATGCTTTGTCTTGGAGAGTTAACGGTAGCAATGCCAGTTTCAGGTTCTTTCCAAAAG
TATGCGACGAAGTTTATTGGACCAGGAACAGGCTTTATGATTGGCTGGCTATATTGGCTTGGCTGGGCAGTAACAGTAGG
ATTAGAATTAACGTCAATCGGTTTAATGATGAAAAGATGGTTTCCGAATGTTGATGTTTGGGTATGGTGCCTTGTATTCG
GCGTTATTTTATATGCTTCAAACGCAATTTCGGCGAAAAGTTATGCTGAATTAGAATTTTGGTTCTCTAGTATTAAAGTA
ATTACAATTCTTGCATTTGTTGTTCTTGGTGGTAGTGCATTATTAGGGTTTATATCATATGACGGAAAAGAAGCAGCACC
TCTTTTCTCTAACTTTGTAAGTGATGGTGGATTATTCCCGAATGGACTAGCTGCTGTATTACTTACAATGATTACAGTTA
ACTTCTCGTTCCAAGGAACAGAGTTAATCGGGATTGCAGCGGGAGAAAGTGAAAATCCAGAAAAAACAATTCCACGTGCG
ATCCGTAATACAGTATGGCGCATTATGTTATTCTTCATTTTAACAATGACGATTTTAGTAGGATTAATTTCTTGGAAAGA
AGCAGGCGTAATTGAAAGTCCATTCGTAGTCGTATTTGATAAAATTGGTATTCCATACGCAGCTGATATTATGAACTTCG
TTATTATTACTGCGTTATTATCTGTAGCGAACTCTGGATTATATGCAGCGACGCGTATACTATGGTCACTTGCAAATGAA
GGAATGGCACCAACTTCCTTCCAGAAAGTAAATAAGCGTGGTATTCCAATTACAGCGCTAGTTGTAACGATTGCTGTAGC
TGGCCTTTCTTTATTCACAAGTTTCCTTGCAGAAGATACAGTATACATGTACTTATTATCTATAGCTGGTTTATCGGCTG
TTTCAAGTTGGATCATTATTGCTCTATCGCAACTTCGCTTTAGAAGTCAGTATATAAAAGGCGGAGGAAAGTTAGAGGAC
TTAAAGTATAGAACACCACTATACCCAATTGTCCCGATTTTAGCCTTAATTACAAATAGCATTGTTGTTATTAGTTTAGC
GTTTATTCCTGAACAAAGAATGGCGTTATACTGTGGTATTCCATTTATCATTTTCTGCTATATATATTATTATATTAGTA
AGAAACGGCAGAAACCGATGAAAGTGGAGATGGAAAAAACAAATGAAACTAACAATCAAACACGATGA

Upstream 100 bases:

>100_bases
AGTTTTAATTTTATATAGAAAATGTAATCGCTTTCGTGTATATTTTTATTATCAGAAAATTTTAACAAGATATAGGGGTA
TTGGTAGGGGGAGGATTTAG

Downstream 100 bases:

>100_bases
TATAGAAGCAGATTTATCGTATGGTCAATTAGCGATTGGAAAAGAAAACGGGTATTCACCGTTACAATTACTCATTTCTT
CTATCGCAGGATGTAGTGCA

Product: amino acid ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MQQPTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKV
ITILAFVVLGGSALLGFISYDGKEAAPLFSNFVSDGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPTSFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDTVYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLED
LKYRTPLYPIVPILALITNSIVVISLAFIPEQRMALYCGIPFIIFCYIYYYISKKRQKPMKVEMEKTNETNNQTR

Sequences:

>Translated_475_residues
MQQPTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKV
ITILAFVVLGGSALLGFISYDGKEAAPLFSNFVSDGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPTSFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDTVYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLED
LKYRTPLYPIVPILALITNSIVVISLAFIPEQRMALYCGIPFIIFCYIYYYISKKRQKPMKVEMEKTNETNNQTR
>Mature_475_residues
MQQPTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYLTMLCLGELTVAMPVSGSFQK
YATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRWFPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKV
ITILAFVVLGGSALLGFISYDGKEAAPLFSNFVSDGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALLSVANSGLYAATRILWSLANE
GMAPTSFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDTVYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLED
LKYRTPLYPIVPILALITNSIVVISLAFIPEQRMALYCGIPFIIFCYIYYYISKKRQKPMKVEMEKTNETNNQTR

Specific function: Putative transport protein involved in arginine degradative pathway. Probably transports arginine or ornithine [H]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=354, Percent_Identity=26.5536723163842, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI71999149, Length=349, Percent_Identity=23.2091690544413, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI258645169, Length=424, Percent_Identity=22.877358490566, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI87081708, Length=464, Percent_Identity=50.4310344827586, Blast_Score=495, Evalue=1e-141,
Organism=Escherichia coli, GI1788480, Length=473, Percent_Identity=41.6490486257928, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1786302, Length=461, Percent_Identity=36.0086767895879, Blast_Score=307, Evalue=1e-84,
Organism=Escherichia coli, GI1786789, Length=455, Percent_Identity=36.4835164835165, Blast_Score=301, Evalue=8e-83,
Organism=Escherichia coli, GI1789017, Length=434, Percent_Identity=36.405529953917, Blast_Score=280, Evalue=1e-76,
Organism=Escherichia coli, GI87081915, Length=473, Percent_Identity=35.5179704016913, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI48994972, Length=463, Percent_Identity=33.6933045356371, Blast_Score=278, Evalue=5e-76,
Organism=Escherichia coli, GI1786602, Length=457, Percent_Identity=35.4485776805252, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1790653, Length=464, Percent_Identity=32.9741379310345, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI87081869, Length=239, Percent_Identity=25.1046025104602, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI2367353, Length=325, Percent_Identity=25.2307692307692, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=363, Percent_Identity=24.7933884297521, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17531343, Length=441, Percent_Identity=24.7165532879819, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6320772, Length=439, Percent_Identity=33.2574031890661, Blast_Score=250, Evalue=4e-67,
Organism=Saccharomyces cerevisiae, GI6324061, Length=421, Percent_Identity=33.2541567695962, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6320717, Length=486, Percent_Identity=30.4526748971193, Blast_Score=227, Evalue=2e-60,
Organism=Saccharomyces cerevisiae, GI6324553, Length=405, Percent_Identity=31.6049382716049, Blast_Score=226, Evalue=8e-60,
Organism=Saccharomyces cerevisiae, GI6324059, Length=440, Percent_Identity=31.5909090909091, Blast_Score=220, Evalue=3e-58,
Organism=Saccharomyces cerevisiae, GI6319824, Length=490, Percent_Identity=29.7959183673469, Blast_Score=211, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6324990, Length=473, Percent_Identity=29.5983086680761, Blast_Score=210, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320251, Length=421, Percent_Identity=31.8289786223278, Blast_Score=208, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6322892, Length=476, Percent_Identity=30.672268907563, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6319542, Length=415, Percent_Identity=32.0481927710843, Blast_Score=206, Evalue=8e-54,
Organism=Saccharomyces cerevisiae, GI6319543, Length=420, Percent_Identity=29.7619047619048, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6321629, Length=420, Percent_Identity=28.8095238095238, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6322967, Length=505, Percent_Identity=28.1188118811881, Blast_Score=196, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6321053, Length=417, Percent_Identity=26.378896882494, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6324924, Length=451, Percent_Identity=28.8248337028825, Blast_Score=187, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6324981, Length=496, Percent_Identity=28.2258064516129, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6319608, Length=439, Percent_Identity=25.9681093394077, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6320364, Length=564, Percent_Identity=23.0496453900709, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24667468, Length=416, Percent_Identity=24.5192307692308, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221512776, Length=431, Percent_Identity=19.953596287703, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24666159, Length=431, Percent_Identity=19.953596287703, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 52286; Mature: 52286

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQPTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYL
CCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
TMLCLGELTVAMPVSGSFQKYATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRW
HHHHHHHHHEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKVITILAFVVLGGSALLGFISY
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCC
DGKEAAPLFSNFVSDGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYAATRILWSLANEGMAPTSFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDT
HHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLEDLKYRTPLYPIVPILALITNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
IVVISLAFIPEQRMALYCGIPFIIFCYIYYYISKKRQKPMKVEMEKTNETNNQTR
HHEEHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCCC
>Mature Secondary Structure
MQQPTNEKLHRTMKSRHLFMIALGGVIGTGFFLGSGYTINQAGPGGAILSYLVGGFIMYL
CCCCCHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHH
TMLCLGELTVAMPVSGSFQKYATKFIGPGTGFMIGWLYWLGWAVTVGLELTSIGLMMKRW
HHHHHHHHHEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPNVDVWVWCLVFGVILYASNAISAKSYAELEFWFSSIKVITILAFVVLGGSALLGFISY
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCC
DGKEAAPLFSNFVSDGGLFPNGLAAVLLTMITVNFSFQGTELIGIAAGESENPEKTIPRA
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHH
IRNTVWRIMLFFILTMTILVGLISWKEAGVIESPFVVVFDKIGIPYAADIMNFVIITALL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHH
SVANSGLYAATRILWSLANEGMAPTSFQKVNKRGIPITALVVTIAVAGLSLFTSFLAEDT
HHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYMYLLSIAGLSAVSSWIIIALSQLRFRSQYIKGGGKLEDLKYRTPLYPIVPILALITNS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCC
IVVISLAFIPEQRMALYCGIPFIIFCYIYYYISKKRQKPMKVEMEKTNETNNQTR
HHEEHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7540694; 9384377 [H]