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The map label for this gene is ydhC [C]

Identifier: 218235325

GI number: 218235325

Start: 3342817

End: 3344016

Strand: Reverse

Name: ydhC [C]

Synonym: BCB4264_A3460

Alternate gene names: 218235325

Gene position: 3344016-3342817 (Counterclockwise)

Preceding gene: 218236144

Following gene: 218230873

Centisome position: 61.71

GC content: 35.83

Gene sequence:

>1200_bases
ATGAAAAAAGTCTCAGTACCATCACTTTTGTTAATGATTATTCTTGTCGCATTTCCGCAAATTAGTGAAACGATTTACAC
ACCGTCTTTACCGGACATTTCAAAGGCGTTACATGTAAGTAATAATGAGGTGCAGTTAACACTTAGTGTGTATTTTGCTG
GATTTGCGTTAGGTGTATTTTTTATTGGGTGGTTATCAGATATAATTGGTCGTCGCCGAGCGATGTTACTTGGAATTGTC
ATATATGGCGCTGGGAGTTTCTTATGCTATATTGCAAATTCCATTGAAGTTTTATTGGTAAGTCGTTTTATTCAAGCGTT
TGGAGCAAGTGCAGGATCCGTGGTTACACAAACGATTCTTCGTGAAAGTGTAGAAGGGCATAAGCGGCATGTTATGTTCG
CTCAAATCTCGGCAGTCATTGCTTTTACACCAGCGATAGGACCGTTAATTGGGGGCTTTCTTGATCAAATGTTTGGTTTT
AAAATAGTATTTTTAAGTTTAGTAGTTATGAGTGTCGGAATTTTTCTGTATACGTTTGTTTCTCTTCCCGAAACAAAGAC
GGGATCAGTAACGAATAAAATAAATGTGTTTTCAGTCTTGAAGAGGCTAATTACAAATCCGAAAGTGGTAACATATGGGC
TATTAATTGGAGGAGCAAATGGTGTTTTATTTAGCTATTATGCAGAAGCGCCGTTTATCTTTATTGAATACTTTCAATTA
TCGCCTAGTATGTATGGATTTCTAGGAATTGTTGTTGCATCTGCTTCTATTGTTGGAGCGAAAATTTCAAAACGTTTACT
TGCTACTTATAAACCAGAGAAAATTATATATATCGGTTGTCTCGTGATGACAGGGGGAGCTATCCTTTTATCTGTTATTA
CGTTTATTGGATCAAATCCGAATGTAATATATATGGTTGTATTTTTAATAGCAATGTTTATATTGTTATTAGGGATTGGA
GTAGCGTTACCTAACTGTTTAAGTTTAGCGTTAGTAGATTTTCAAGATGTTATTGGTACAGCCGGAGCATTGTTTAGCTT
AGGATACTATGTAATTGTAACGATGACAATTTTGGGGATGAGTCAGCTGCATACAGGCTCGTTACTGGTGATGCCACTTT
ATTTTCTGGTTATTGTAGTTATAATGGTAGTGTTTACTAGGGTATTTATCTTTGGTAAGCAAACTTCGAAATCGATTTAA

Upstream 100 bases:

>100_bases
TTGTTTTATGACCGGATTTCTATAATGGCCCCTCCTGTTCCGTAGCTAAGGAAAGTCTTTTTATTTCTGAGATTTTCAAA
GTTATAGGAGGGTATGAAAA

Downstream 100 bases:

>100_bases
ATATGAAATTGTAAAAGAGTCTCATTTTTTAATGAGACTCTTTTATATTTTGGCTGGGGTAAAGAAGTTAGTAGTTTATT
AATATATTAAATTTCTCATT

Product: drug resistance transporter, Bcr/CflA family

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRRAMLLGIV
IYGAGSFLCYIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTGSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
SPSMYGFLGIVVASASIVGAKISKRLLATYKPEKIIYIGCLVMTGGAILLSVITFIGSNPNVIYMVVFLIAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTILGMSQLHTGSLLVMPLYFLVIVVIMVVFTRVFIFGKQTSKSI

Sequences:

>Translated_399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRRAMLLGIV
IYGAGSFLCYIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTGSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
SPSMYGFLGIVVASASIVGAKISKRLLATYKPEKIIYIGCLVMTGGAILLSVITFIGSNPNVIYMVVFLIAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTILGMSQLHTGSLLVMPLYFLVIVVIMVVFTRVFIFGKQTSKSI
>Mature_399_residues
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVFFIGWLSDIIGRRRAMLLGIV
IYGAGSFLCYIANSIEVLLVSRFIQAFGASAGSVVTQTILRESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGF
KIVFLSLVVMSVGIFLYTFVSLPETKTGSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
SPSMYGFLGIVVASASIVGAKISKRLLATYKPEKIIYIGCLVMTGGAILLSVITFIGSNPNVIYMVVFLIAMFILLLGIG
VALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTILGMSQLHTGSLLVMPLYFLVIVVIMVVFTRVFIFGKQTSKSI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=325, Percent_Identity=26.1538461538462, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082312, Length=326, Percent_Identity=26.0736196319018, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788509, Length=230, Percent_Identity=27.3913043478261, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790146, Length=272, Percent_Identity=22.7941176470588, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787065, Length=383, Percent_Identity=24.2819843342037, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790794, Length=381, Percent_Identity=25.4593175853018, Blast_Score=68, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6324264, Length=164, Percent_Identity=31.0975609756098, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43231; Mature: 43231

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVSVPSLLLMIILVAFPQISETIYTPSLPDISKALHVSNNEVQLTLSVYFAGFALGVF
CCCCCHHHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHCCCCCCEEEEHHHHHHHHHHHHH
FIGWLSDIIGRRRAMLLGIVIYGAGSFLCYIANSIEVLLVSRFIQAFGASAGSVVTQTIL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
RESVEGHKRHVMFAQISAVIAFTPAIGPLIGGFLDQMFGFKIVFLSLVVMSVGIFLYTFV
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLPETKTGSVTNKINVFSVLKRLITNPKVVTYGLLIGGANGVLFSYYAEAPFIFIEYFQL
CCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEHHCCCCEEEEEHHHC
SPSMYGFLGIVVASASIVGAKISKRLLATYKPEKIIYIGCLVMTGGAILLSVITFIGSNP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCC
NVIYMVVFLIAMFILLLGIGVALPNCLSLALVDFQDVIGTAGALFSLGYYVIVTMTILGM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SQLHTGSLLVMPLYFLVIVVIMVVFTRVFIFGKQTSKSI
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC
>Mature Secondary Structure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HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA