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The map label for this gene is yusP [H]

Identifier: 218234907

GI number: 218234907

Start: 684345

End: 685958

Strand: Direct

Name: yusP [H]

Synonym: BCB4264_A0695

Alternate gene names: 218234907

Gene position: 684345-685958 (Clockwise)

Preceding gene: 218235502

Following gene: 218234322

Centisome position: 12.63

GC content: 36.99

Gene sequence:

>1614_bases
ATGGAGCAACAAGAAAATCAAAATAGAAAGTTGTTGTTAATCGGTTTAATTATCGCGATGCTATTTGCTGCATTAGATGG
AACAATTGTCGGTACAGCAATGCCACGTATCGTCGGTGACCTAGGTGGATTAAGCTTAATGACATGGTTAACAACAGCTT
ATATGTTAACATCAACGACAGTTGTACCAATTGCAGGTAAATTAGCTGATTTACTTGGTCGTCGTAACGTATATATAACA
GGGCTAGTTATTTTCATGATTGGTTCGGCGTTATGTGGTATGGCAAATGGTATGACAGAATTAATTATTTTCCGTGGTAT
TCAAGGTCTTGGTGGCGGTATTATGATGCCAATGGCTATGATTATTATTGGAGATATGTTCACGGGAAAAGAACGTGCGA
AATGGCAAGGTATTTTTGGGGCGTTATACGGCCTTGCTTCTGTAATTGGACCACAAGTTGGTGGTTGGATTGTAGATGCA
GTGAACTGGAGATGGGTATTCTACATTAACTTACCGGTTGGTATTTTAGCAACAATCTTTATTGCAATGGGATTAAAATC
ACATAAACAAACAGGACCAATTAAAATTGATATCGCTGGAATCTTTACGATGATTCTCGGTGTTGTAAGTTTATTACTTG
CGCTAACGTTTGGCGGAAAAGATTATGCATGGGATTCTTGGCAAATTATCGGTTTATTTGCACTAGCTGTAATTGGTATC
GTTAGCTTTGTTATCGTTGAAACGAAAGCTGAAGAGCCAATTTTACCAATGCACTTCTTTAAAAATCGCACATTTACAAT
ACTGAATGCGATTGGATTCTTTATGAGTATTGGAATGTTCGGTGCGATTATGTTCGTACCATTCTTCATGCAAGGGATTG
TAGGAGTAAGTGCTGCTGAATCAGGAACAATTATGACTCCAATGATGATTACAATGATTGTGATGAGTATTATCGGTGGG
CAACTTGTATTAAAAGTTGGTGTAAAACCACAAATTATCGCAGGTATGCTTATTATGGCCGGTGGTTTCTGGTTATTAAC
AACGATGGATATGCACACAACGAAGCTTACAGCTACTTCTTATATGATGGTTATCGGTTTAGGAATGGGTCTTGTAATGC
CTACATTAACATTAGCGTTACAAGAAAGCTTCCCGAAAAAAGACCTTGGTGTCGTAACGTCATCAAGTCAATTCTTCCGA
CAAATCGGTGGTACATTTGGTATTACAATTTTAGGGTCAATTATGAATAACACTTCAGGTACGACATTAACAAAAAATTT
AGTACCTGTATTAGATACATTCCCGAAAGAAGCGGGACAAATGGTAACGAAATTTAAAGATATGATTCACACAGATCCAC
AAGGTTTATATTCAATGCTATTTAGCCCAGAGGCATTAAAACAAATGCCAGAAGCGTTCGCTAACAGCATTGTACCTATT
TTGAAAAACTCTTTAGTAGACTCGCTTCATACTGTATTCTTAACAGGATTAGTATTTATCGTAGTAGGTGCCATCTTTAC
GATTTTCCTACAAAAAATTAAACTATCAGATCGTAAAAAAGATGCTGAAGAGCCTGCTTTAGAAGAAAAAGAAAAAACTG
TATCATACTCGTAA

Upstream 100 bases:

>100_bases
GAAAGAGAAGATTTATTACGTCTCTTTGAGAAGTTAGAAACCATTATTTGCGGGACACAAGAGAAAAAAGAGAATAACTA
AGAGGAATTGAGGAGATTAC

Downstream 100 bases:

>100_bases
TGAAGGAGCATCGTCTTATGGCGGTGCTTTTTTGAGTATAACCTTAAAAGCTTTTTAGTGAGAAATGATTGACGTATTTT
TAGAAATACGTTATATTATT

Product: putative multidrug resistance protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 537

Protein sequence:

>537_residues
MEQQENQNRKLLLIGLIIAMLFAALDGTIVGTAMPRIVGDLGGLSLMTWLTTAYMLTSTTVVPIAGKLADLLGRRNVYIT
GLVIFMIGSALCGMANGMTELIIFRGIQGLGGGIMMPMAMIIIGDMFTGKERAKWQGIFGALYGLASVIGPQVGGWIVDA
VNWRWVFYINLPVGILATIFIAMGLKSHKQTGPIKIDIAGIFTMILGVVSLLLALTFGGKDYAWDSWQIIGLFALAVIGI
VSFVIVETKAEEPILPMHFFKNRTFTILNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAESGTIMTPMMITMIVMSIIGG
QLVLKVGVKPQIIAGMLIMAGGFWLLTTMDMHTTKLTATSYMMVIGLGMGLVMPTLTLALQESFPKKDLGVVTSSSQFFR
QIGGTFGITILGSIMNNTSGTTLTKNLVPVLDTFPKEAGQMVTKFKDMIHTDPQGLYSMLFSPEALKQMPEAFANSIVPI
LKNSLVDSLHTVFLTGLVFIVVGAIFTIFLQKIKLSDRKKDAEEPALEEKEKTVSYS

Sequences:

>Translated_537_residues
MEQQENQNRKLLLIGLIIAMLFAALDGTIVGTAMPRIVGDLGGLSLMTWLTTAYMLTSTTVVPIAGKLADLLGRRNVYIT
GLVIFMIGSALCGMANGMTELIIFRGIQGLGGGIMMPMAMIIIGDMFTGKERAKWQGIFGALYGLASVIGPQVGGWIVDA
VNWRWVFYINLPVGILATIFIAMGLKSHKQTGPIKIDIAGIFTMILGVVSLLLALTFGGKDYAWDSWQIIGLFALAVIGI
VSFVIVETKAEEPILPMHFFKNRTFTILNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAESGTIMTPMMITMIVMSIIGG
QLVLKVGVKPQIIAGMLIMAGGFWLLTTMDMHTTKLTATSYMMVIGLGMGLVMPTLTLALQESFPKKDLGVVTSSSQFFR
QIGGTFGITILGSIMNNTSGTTLTKNLVPVLDTFPKEAGQMVTKFKDMIHTDPQGLYSMLFSPEALKQMPEAFANSIVPI
LKNSLVDSLHTVFLTGLVFIVVGAIFTIFLQKIKLSDRKKDAEEPALEEKEKTVSYS
>Mature_537_residues
MEQQENQNRKLLLIGLIIAMLFAALDGTIVGTAMPRIVGDLGGLSLMTWLTTAYMLTSTTVVPIAGKLADLLGRRNVYIT
GLVIFMIGSALCGMANGMTELIIFRGIQGLGGGIMMPMAMIIIGDMFTGKERAKWQGIFGALYGLASVIGPQVGGWIVDA
VNWRWVFYINLPVGILATIFIAMGLKSHKQTGPIKIDIAGIFTMILGVVSLLLALTFGGKDYAWDSWQIIGLFALAVIGI
VSFVIVETKAEEPILPMHFFKNRTFTILNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAESGTIMTPMMITMIVMSIIGG
QLVLKVGVKPQIIAGMLIMAGGFWLLTTMDMHTTKLTATSYMMVIGLGMGLVMPTLTLALQESFPKKDLGVVTSSSQFFR
QIGGTFGITILGSIMNNTSGTTLTKNLVPVLDTFPKEAGQMVTKFKDMIHTDPQGLYSMLFSPEALKQMPEAFANSIVPI
LKNSLVDSLHTVFLTGLVFIVVGAIFTIFLQKIKLSDRKKDAEEPALEEKEKTVSYS

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=462, Percent_Identity=26.4069264069264, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1788710, Length=405, Percent_Identity=28.1481481481481, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1790195, Length=335, Percent_Identity=28.0597014925373, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87081983, Length=414, Percent_Identity=24.8792270531401, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1788392, Length=397, Percent_Identity=28.9672544080605, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790146, Length=190, Percent_Identity=27.3684210526316, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322958, Length=572, Percent_Identity=27.6223776223776, Blast_Score=161, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6323735, Length=347, Percent_Identity=28.2420749279539, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319770, Length=406, Percent_Identity=26.1083743842365, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6319783, Length=488, Percent_Identity=26.844262295082, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321663, Length=554, Percent_Identity=24.0072202166065, Blast_Score=107, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6325455, Length=231, Percent_Identity=28.1385281385281, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324954, Length=423, Percent_Identity=24.113475177305, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323520, Length=365, Percent_Identity=26.8493150684932, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321740, Length=459, Percent_Identity=21.5686274509804, Blast_Score=63, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 58150; Mature: 58150

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQQENQNRKLLLIGLIIAMLFAALDGTIVGTAMPRIVGDLGGLSLMTWLTTAYMLTSTT
CCCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
VVPIAGKLADLLGRRNVYITGLVIFMIGSALCGMANGMTELIIFRGIQGLGGGIMMPMAM
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHH
IIIGDMFTGKERAKWQGIFGALYGLASVIGPQVGGWIVDAVNWRWVFYINLPVGILATIF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEEECCHHHHHHHH
IAMGLKSHKQTGPIKIDIAGIFTMILGVVSLLLALTFGGKDYAWDSWQIIGLFALAVIGI
HHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VSFVIVETKAEEPILPMHFFKNRTFTILNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAE
HHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SGTIMTPMMITMIVMSIIGGQLVLKVGVKPQIIAGMLIMAGGFWLLTTMDMHTTKLTATS
CCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCHHEEEECCHHHHHHHHHH
YMMVIGLGMGLVMPTLTLALQESFPKKDLGVVTSSSQFFRQIGGTFGITILGSIMNNTSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCCCHHHHHHHHHHCCCCC
TTLTKNLVPVLDTFPKEAGQMVTKFKDMIHTDPQGLYSMLFSPEALKQMPEAFANSIVPI
CEEHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LKNSLVDSLHTVFLTGLVFIVVGAIFTIFLQKIKLSDRKKDAEEPALEEKEKTVSYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MEQQENQNRKLLLIGLIIAMLFAALDGTIVGTAMPRIVGDLGGLSLMTWLTTAYMLTSTT
CCCCCCCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCC
VVPIAGKLADLLGRRNVYITGLVIFMIGSALCGMANGMTELIIFRGIQGLGGGIMMPMAM
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHH
IIIGDMFTGKERAKWQGIFGALYGLASVIGPQVGGWIVDAVNWRWVFYINLPVGILATIF
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEEEEEECCHHHHHHHH
IAMGLKSHKQTGPIKIDIAGIFTMILGVVSLLLALTFGGKDYAWDSWQIIGLFALAVIGI
HHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VSFVIVETKAEEPILPMHFFKNRTFTILNAIGFFMSIGMFGAIMFVPFFMQGIVGVSAAE
HHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
SGTIMTPMMITMIVMSIIGGQLVLKVGVKPQIIAGMLIMAGGFWLLTTMDMHTTKLTATS
CCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCHHEEEECCHHHHHHHHHH
YMMVIGLGMGLVMPTLTLALQESFPKKDLGVVTSSSQFFRQIGGTFGITILGSIMNNTSG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHCCCHHHHHHHHHHCCCCC
TTLTKNLVPVLDTFPKEAGQMVTKFKDMIHTDPQGLYSMLFSPEALKQMPEAFANSIVPI
CEEHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LKNSLVDSLHTVFLTGLVFIVVGAIFTIFLQKIKLSDRKKDAEEPALEEKEKTVSYS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]