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The map label for this gene is frr [H]

Identifier: 218234587

GI number: 218234587

Start: 3844454

End: 3845011

Strand: Reverse

Name: frr [H]

Synonym: BCB4264_A3922

Alternate gene names: 218234587

Gene position: 3845011-3844454 (Counterclockwise)

Preceding gene: 218233853

Following gene: 218232974

Centisome position: 70.95

GC content: 36.2

Gene sequence:

>558_bases
ATGGGACAACAAGTATTGAAGTCTTCAAATGAAAAAATGGAAAAAGCAGTTGCTGCTTATTCTCGTGAATTAGCAACAGT
TCGTGCTGGCCGTGCAAACGCGTCTGTATTAGATAAGGTACAAGTTGATTACTACGGTGCACCAACACCAGTTGTGCAAT
TAGCGAACATTACAGTTCCAGAAGCACGTTTACTAGTAATTCAACCTTATGATAAAACTTCTATCGGTGATATTGAAAAA
GCAATTTTAAAAGCAGATTTAGGCTTAAACCCTTCTAATGATGGAACTGTAATTCGTATTGCATTTCCTGCACTAACAGA
AGAGCGTCGTCGTGATCTTGTAAAAGTTGTGAAAAAATATGCTGAAGAAGCAAAAGTTGCTGTTCGTAACGTACGTCGTG
ACGGAAATGATGATCTTAAGAAGCTTGAAAAAGCTGGCGAGATTACAGAAGATGATTTAAGAGGATATACTGAAGATATC
CAAAAAGAAACAGATAAATATATTGCAAAAGTTGACGAAATCGCAAAAAACAAAGAAAAAGAAATCATGGAAGTGTAA

Upstream 100 bases:

>100_bases
ATGATATTCCATTAATTGTATTCTCAGTTATGGAAAAAGGTAATATTAAACGTGCCGTTTTAGGCGAAAATATCGGAACA
GTGGTAAGGGGGAAATAAAT

Downstream 100 bases:

>100_bases
TAGCGATAACTTCGCAAATATGACCCTCTTCTTAAGGGGGTCTTTTTACACTTTTAGGCATACGTCTGCTTGCTGGAGGG
TATGAATGATGTTTAAAAAC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MGQQVLKSSNEKMEKAVAAYSRELATVRAGRANASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEK
AILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDI
QKETDKYIAKVDEIAKNKEKEIMEV

Sequences:

>Translated_185_residues
MGQQVLKSSNEKMEKAVAAYSRELATVRAGRANASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEK
AILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDI
QKETDKYIAKVDEIAKNKEKEIMEV
>Mature_184_residues
GQQVLKSSNEKMEKAVAAYSRELATVRAGRANASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEKA
ILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQ
KETDKYIAKVDEIAKNKEKEIMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=6e-12,
Organism=Homo sapiens, GI291042689, Length=186, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=47.2826086956522, Blast_Score=174, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24661488, Length=175, Percent_Identity=26.2857142857143, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20647; Mature: 20516

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQVLKSSNEKMEKAVAAYSRELATVRAGRANASVLDKVQVDYYGAPTPVVQLANITVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCC
EARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
AEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
EIMEV
HHHCC
>Mature Secondary Structure 
GQQVLKSSNEKMEKAVAAYSRELATVRAGRANASVLDKVQVDYYGAPTPVVQLANITVP
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHCCCCC
EARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
AEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
EIMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA