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The map label for this gene is sipS2 [H]

Identifier: 218234536

GI number: 218234536

Start: 3860216

End: 3860767

Strand: Reverse

Name: sipS2 [H]

Synonym: BCB4264_A3937

Alternate gene names: 218234536

Gene position: 3860767-3860216 (Counterclockwise)

Preceding gene: 218231872

Following gene: 218236121

Centisome position: 71.24

GC content: 36.05

Gene sequence:

>552_bases
ATGAAAAAAGAGAAGAGTTCACTTTGGGAATGGATTAAAGCAATTTTGATTGCTGTTGTATTAGCTGGTGTTATTAGACA
GTTTTTCTTTGCGCCAATTCTCGTAGACGGGGTATCGATGGCACCTACTTTACATGATCGTGATCGAATGATTGTGAATA
AAATTGGTTATCACATTGGAGATCCAAAACGCTTTGATATTATCGTATTTCGAGCAACAGAAGATAAAGATTACATTAAG
CGCATTATAGGCCTGCCAGGCGATGAAATAGAGTATCGTAATGATAAACTGTATGTTAACGGAAAGGCTTATGAGGAGCC
GTATTTAGACAAGCAGAAAAAGCAAATTGCTGATGGACCGCTTACATATGATTTTAATCTTGAAGAAATGACAGGCAAGA
AAACCGTTCCAAAAGATCAATTATTTGTTTTAGGTGATAATCGTCGTTTTAGTAAAGATAGCCGTTCAATCGGTACGATT
TCAATGGATCAAGTAATTGGTAAAGCTAATATGTTATATTGGCCGTTAGAAGACGCACGTATTGTGAAATAA

Upstream 100 bases:

>100_bases
ACATGTATGGGAGCTTGTAAATGCACAAGCTCCCTTTTTCCAATCTATATGAAATTTTGGTATAATACGAGCAGTTTACA
TAACCGTGGAGGGGAAATGC

Downstream 100 bases:

>100_bases
ATGAAAAAGAAGGTGGCAACATGGTAATTCAATGGTTTCCAGGGCATATGGCGAAGGCTAGACGCCAAGTAACGGAGAAA
TTAAAATTAATTGATGTTGT

Product: signal peptidase I S

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKKEKSSLWEWIKAILIAVVLAGVIRQFFFAPILVDGVSMAPTLHDRDRMIVNKIGYHIGDPKRFDIIVFRATEDKDYIK
RIIGLPGDEIEYRNDKLYVNGKAYEEPYLDKQKKQIADGPLTYDFNLEEMTGKKTVPKDQLFVLGDNRRFSKDSRSIGTI
SMDQVIGKANMLYWPLEDARIVK

Sequences:

>Translated_183_residues
MKKEKSSLWEWIKAILIAVVLAGVIRQFFFAPILVDGVSMAPTLHDRDRMIVNKIGYHIGDPKRFDIIVFRATEDKDYIK
RIIGLPGDEIEYRNDKLYVNGKAYEEPYLDKQKKQIADGPLTYDFNLEEMTGKKTVPKDQLFVLGDNRRFSKDSRSIGTI
SMDQVIGKANMLYWPLEDARIVK
>Mature_183_residues
MKKEKSSLWEWIKAILIAVVLAGVIRQFFFAPILVDGVSMAPTLHDRDRMIVNKIGYHIGDPKRFDIIVFRATEDKDYIK
RIIGLPGDEIEYRNDKLYVNGKAYEEPYLDKQKKQIADGPLTYDFNLEEMTGKKTVPKDQLFVLGDNRRFSKDSRSIGTI
SMDQVIGKANMLYWPLEDARIVK

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=91, Percent_Identity=40.6593406593407, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21160; Mature: 21160

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEKSSLWEWIKAILIAVVLAGVIRQFFFAPILVDGVSMAPTLHDRDRMIVNKIGYHIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCC
DPKRFDIIVFRATEDKDYIKRIIGLPGDEIEYRNDKLYVNGKAYEEPYLDKQKKQIADGP
CCCEEEEEEEEECCCHHHHHHHHCCCCCCEEECCCEEEECCCCCCCCCCCHHHHHHCCCC
LTYDFNLEEMTGKKTVPKDQLFVLGDNRRFSKDSRSIGTISMDQVIGKANMLYWPLEDAR
EEEECCHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEHHHHHCCCCEEEEECCCCE
IVK
ECC
>Mature Secondary Structure
MKKEKSSLWEWIKAILIAVVLAGVIRQFFFAPILVDGVSMAPTLHDRDRMIVNKIGYHIG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCC
DPKRFDIIVFRATEDKDYIKRIIGLPGDEIEYRNDKLYVNGKAYEEPYLDKQKKQIADGP
CCCEEEEEEEEECCCHHHHHHHHCCCCCCEEECCCEEEECCCCCCCCCCCHHHHHHCCCC
LTYDFNLEEMTGKKTVPKDQLFVLGDNRRFSKDSRSIGTISMDQVIGKANMLYWPLEDAR
EEEECCHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEHHHHHCCCCEEEEECCCCE
IVK
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]