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The map label for this gene is narA2 [H]

Identifier: 218234531

GI number: 218234531

Start: 3589866

End: 3590882

Strand: Reverse

Name: narA2 [H]

Synonym: BCB4264_A3677

Alternate gene names: 218234531

Gene position: 3590882-3589866 (Counterclockwise)

Preceding gene: 218232440

Following gene: 218233960

Centisome position: 66.26

GC content: 34.71

Gene sequence:

>1017_bases
ATGAAATCAGTTACATTAGACAAGTTGCAACGTCCGTTAAAGGATTTACGTATTTCAGTTACTGATCGCTGTAATTTTCG
CTGCCGATATTGTATGCCAGAAGAAATATTTGGTCCTGATTACTCGTTTTTGTCTAATGATAAAATTTTATCTTTTGATG
AAATTGAAAGGATAACACGTATTTTCGTTTCTTTAGGTGTGAGAAAATTACGGATTACAGGCGGAGAACCGTTACTTCGA
AGAGGGCTTCCAAAGCTTATTGAGCGTCTTAATAAAATTGATGGTGTAGAAGATATCGGTTTAACAACCAATGGATCGTT
ACTTAAAAAGTTTGCTCCTGATTTATATAAGGCGGGACTATCACGTGTAACAGTTAGCTTAGATTCCTTAGAAGAAGAGC
GGTTTTTCTATTTAAATGGTAATAGGAGCAAAGTGCAAAGGGTTCTGGAAGGAATACAGGCTGCAGCTGAAGTTGGAATG
AAAATTAAAATAAACATGGTCGTTCAAAAGGGAAAAAACGAACAGGACATTTTGCAGATGGCGCAATATTTTAAGGAAAA
TAAGCATATTCTTCGTTTTATTGAGTATATGGATGTTGGAAATTATAATGGTTGGGATTTAAAAGAGGTCGTCTCTAAAC
AAGAAATAGTAGATAGGATTCATCAAGTTATGCCGTTAGAACGGATAGAAGCAAATTATTCTGGTGAAGTGGCTACTAGG
TATCGTTATATAGGAAGCGATGAGGAAATAGGTATTATTTCATCAGTAACAGATTCTTTTTGCTCATCATGTACGAGAGC
TCGTATTTCTGCAGAAGGAAAATTATATACTTGCTTATTTGCTTCTAAAGGAAATGATTTAAGAGAATTGCTTCGTTCTG
AACATACAGATGAGGACATTACAGATGTAGTACGCGATATATGGAATAATAGGGAAGATCGTTATTCAGATGAACGCTTA
AATCATACAAATAAGAAAACAATACCTAAAATTGAAATGTCACATATCGGTGGTTAA

Upstream 100 bases:

>100_bases
TTAGGTATTACGACAATAGGATTTATTCGTAATCACTCCTTAAATGTATATACCCATCCAGAACGTGTTTTAAATATAAA
ATAAAAGTGAGGCAATGAAG

Downstream 100 bases:

>100_bases
TATATAAAGCTAGCGTCATAGTGAAAAATGGAAAATTTACAAGAGTTGTGGATTTTCTATTTTATAGTAAAAGTGATGAT
TGATATCTCTGTAAAAGATG

Product: molybdenum cofactor biosynthesis protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKSVTLDKLQRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLSNDKILSFDEIERITRIFVSLGVRKLRITGGEPLLR
RGLPKLIERLNKIDGVEDIGLTTNGSLLKKFAPDLYKAGLSRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGM
KIKINMVVQKGKNEQDILQMAQYFKENKHILRFIEYMDVGNYNGWDLKEVVSKQEIVDRIHQVMPLERIEANYSGEVATR
YRYIGSDEEIGIISSVTDSFCSSCTRARISAEGKLYTCLFASKGNDLRELLRSEHTDEDITDVVRDIWNNREDRYSDERL
NHTNKKTIPKIEMSHIGG

Sequences:

>Translated_338_residues
MKSVTLDKLQRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLSNDKILSFDEIERITRIFVSLGVRKLRITGGEPLLR
RGLPKLIERLNKIDGVEDIGLTTNGSLLKKFAPDLYKAGLSRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGM
KIKINMVVQKGKNEQDILQMAQYFKENKHILRFIEYMDVGNYNGWDLKEVVSKQEIVDRIHQVMPLERIEANYSGEVATR
YRYIGSDEEIGIISSVTDSFCSSCTRARISAEGKLYTCLFASKGNDLRELLRSEHTDEDITDVVRDIWNNREDRYSDERL
NHTNKKTIPKIEMSHIGG
>Mature_338_residues
MKSVTLDKLQRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLSNDKILSFDEIERITRIFVSLGVRKLRITGGEPLLR
RGLPKLIERLNKIDGVEDIGLTTNGSLLKKFAPDLYKAGLSRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGM
KIKINMVVQKGKNEQDILQMAQYFKENKHILRFIEYMDVGNYNGWDLKEVVSKQEIVDRIHQVMPLERIEANYSGEVATR
YRYIGSDEEIGIISSVTDSFCSSCTRARISAEGKLYTCLFASKGNDLRELLRSEHTDEDITDVVRDIWNNREDRYSDERL
NHTNKKTIPKIEMSHIGG

Specific function: Together with moaC, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG2896

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. MoaA family [H]

Homologues:

Organism=Homo sapiens, GI22027536, Length=300, Percent_Identity=36.6666666666667, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI116734668, Length=300, Percent_Identity=36.6666666666667, Blast_Score=202, Evalue=3e-52,
Organism=Escherichia coli, GI1786999, Length=345, Percent_Identity=33.9130434782609, Blast_Score=181, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI32566329, Length=334, Percent_Identity=33.2335329341317, Blast_Score=193, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI32566331, Length=312, Percent_Identity=33.6538461538462, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17561210, Length=334, Percent_Identity=32.9341317365269, Blast_Score=190, Evalue=1e-48,
Organism=Drosophila melanogaster, GI28574490, Length=319, Percent_Identity=34.1692789968652, Blast_Score=194, Evalue=5e-50,
Organism=Drosophila melanogaster, GI28574488, Length=303, Percent_Identity=34.983498349835, Blast_Score=191, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR013483
- InterPro:   IPR000385
- InterPro:   IPR010505
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06463 Mob_synth_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 38964; Mature: 38964

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS01305 MOAA_NIFB_PQQE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSVTLDKLQRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLSNDKILSFDEIERITR
CCCCCHHHHHHHHHHCEEEEECCCCCEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHH
IFVSLGVRKLRITGGEPLLRRGLPKLIERLNKIDGVEDIGLTTNGSLLKKFAPDLYKAGL
HHHHHCCEEEEECCCCHHHHHCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCHHHHHCCH
SRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGMKIKINMVVQKGKNEQDILQM
HHEEHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHH
AQYFKENKHILRFIEYMDVGNYNGWDLKEVVSKQEIVDRIHQVMPLERIEANYSGEVATR
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHH
YRYIGSDEEIGIISSVTDSFCSSCTRARISAEGKLYTCLFASKGNDLRELLRSEHTDEDI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCCHHH
TDVVRDIWNNREDRYSDERLNHTNKKTIPKIEMSHIGG
HHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHCCCC
>Mature Secondary Structure
MKSVTLDKLQRPLKDLRISVTDRCNFRCRYCMPEEIFGPDYSFLSNDKILSFDEIERITR
CCCCCHHHHHHHHHHCEEEEECCCCCEEEECCCHHHCCCCCCCCCCCCCCCHHHHHHHHH
IFVSLGVRKLRITGGEPLLRRGLPKLIERLNKIDGVEDIGLTTNGSLLKKFAPDLYKAGL
HHHHHCCEEEEECCCCHHHHHCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCHHHHHCCH
SRVTVSLDSLEEERFFYLNGNRSKVQRVLEGIQAAAEVGMKIKINMVVQKGKNEQDILQM
HHEEHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHH
AQYFKENKHILRFIEYMDVGNYNGWDLKEVVSKQEIVDRIHQVMPLERIEANYSGEVATR
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHH
YRYIGSDEEIGIISSVTDSFCSSCTRARISAEGKLYTCLFASKGNDLRELLRSEHTDEDI
EEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCCCHHH
TDVVRDIWNNREDRYSDERLNHTNKKTIPKIEMSHIGG
HHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA