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The map label for this gene is ocd2 [H]

Identifier: 218234462

GI number: 218234462

Start: 915747

End: 916724

Strand: Direct

Name: ocd2 [H]

Synonym: BCB4264_A0944

Alternate gene names: 218234462

Gene position: 915747-916724 (Clockwise)

Preceding gene: 218232621

Following gene: 218233727

Centisome position: 16.9

GC content: 41.21

Gene sequence:

>978_bases
ATGCTAGTTATAAGCGCGAATGAACAAAGAAACTTAGTAAATATGAATGAAGTTATTGAATACGCGGCGCTTGCTTTAAA
AGAATTTTCCGCAGAAAGAACGATTACACCAATAAGAGGCTCATTACCATTTGCGAACGAGCAAAATACGGCATTAATTA
TGCCTTCAGTAGCGGAAGGACTTGAGGCACTTGGAGTAAAAATAGTAACGGTAGTCCCGCAAAATAAACAGATAGGAAAG
AAAACGATCAATGGGATTGTGATGCTATCAGACTTTCAAACGGGAGAACCGCTCGCACTTCTAGAAGGATCGTACTTAAC
GATGATCCGAACGGGCGCCTTATCAGGAGTAGCGACAAAATATTTAGCTCGTCATAACGCAAAAACTTTATGCATTATCG
GCACGGGCGAACAAGCGAAAGGAATTGCCGAAGCAATATTTGCAGTTAGAGATATCGAAAAAGTCATCTTATACAATCGA
ACAGAAGAAAAAGCGTATGCATTTGCGCAACATATACAAGAGAAATTTGGTAAACCTGCTTACGTTTACAGGGATCCAAA
TGAAGCAATACGTGAAGCAGACATTATCGTCACAACTACGAACGCAACCACACCAGTCTTCTCAGAAACACTACAAAAAG
GCGTCCACGTAAACGCCGTCGGCTCATTCAGACCGAGCATGCAAGAACTACCCTCACATGCCATAGCTGAAGCAAACAAA
GTAGTAGTCGAATCAAAAGAAGCAGCACTAGACGAAACAGGAGACCTTCAAGTTCCGATAAAAGAAGGTCTATTCAAAGC
AAACGCCATTCACGCTGAACTTGGTCAAATTATAAGCAAAGAAAAAGCTGGCCGCGAAAATGATGAAGAGATTACTATTT
TCAAATCAGTTGGTTTGGCGGTAGTAGATATTATCGTTGCGAAGTATTTGTATGAGAAAGCGGTGGAGCAAGGGATGGGG
AATAAGATTGAGTTTTGA

Upstream 100 bases:

>100_bases
GGGAATGCCTTTATTACAGGATTTCATCAGTTCGTTGTAGACCTGAGAGATGATTTGAATCGAGGATTTTTGTTAGGATA
GGAGGAGGGGGTGGAAAGAT

Downstream 100 bases:

>100_bases
GACTGCCTTTTGGTGGTCTTTTTTTCAATTCATCAAATGTCATGATAACCTCCTAAATGTGTTTTTTGTCTTTAATCCCA
TTCTACATTTTCGATCATAT

Product: ornithine cyclodeaminase

Products: NA

Alternate protein names: OCD 2 [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLVISANEQRNLVNMNEVIEYAALALKEFSAERTITPIRGSLPFANEQNTALIMPSVAEGLEALGVKIVTVVPQNKQIGK
KTINGIVMLSDFQTGEPLALLEGSYLTMIRTGALSGVATKYLARHNAKTLCIIGTGEQAKGIAEAIFAVRDIEKVILYNR
TEEKAYAFAQHIQEKFGKPAYVYRDPNEAIREADIIVTTTNATTPVFSETLQKGVHVNAVGSFRPSMQELPSHAIAEANK
VVVESKEAALDETGDLQVPIKEGLFKANAIHAELGQIISKEKAGRENDEEITIFKSVGLAVVDIIVAKYLYEKAVEQGMG
NKIEF

Sequences:

>Translated_325_residues
MLVISANEQRNLVNMNEVIEYAALALKEFSAERTITPIRGSLPFANEQNTALIMPSVAEGLEALGVKIVTVVPQNKQIGK
KTINGIVMLSDFQTGEPLALLEGSYLTMIRTGALSGVATKYLARHNAKTLCIIGTGEQAKGIAEAIFAVRDIEKVILYNR
TEEKAYAFAQHIQEKFGKPAYVYRDPNEAIREADIIVTTTNATTPVFSETLQKGVHVNAVGSFRPSMQELPSHAIAEANK
VVVESKEAALDETGDLQVPIKEGLFKANAIHAELGQIISKEKAGRENDEEITIFKSVGLAVVDIIVAKYLYEKAVEQGMG
NKIEF
>Mature_325_residues
MLVISANEQRNLVNMNEVIEYAALALKEFSAERTITPIRGSLPFANEQNTALIMPSVAEGLEALGVKIVTVVPQNKQIGK
KTINGIVMLSDFQTGEPLALLEGSYLTMIRTGALSGVATKYLARHNAKTLCIIGTGEQAKGIAEAIFAVRDIEKVILYNR
TEEKAYAFAQHIQEKFGKPAYVYRDPNEAIREADIIVTTTNATTPVFSETLQKGVHVNAVGSFRPSMQELPSHAIAEANK
VVVESKEAALDETGDLQVPIKEGLFKANAIHAELGQIISKEKAGRENDEEITIFKSVGLAVVDIIVAKYLYEKAVEQGMG
NKIEF

Specific function: Porphyrin biosynthesis by the C5 pathway; first step. [C]

COG id: COG2423

COG function: function code E; Predicted ornithine cyclodeaminase, mu-crystallin homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ornithine cyclodeaminase family [H]

Homologues:

Organism=Homo sapiens, GI62241008, Length=286, Percent_Identity=34.6153846153846, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4503065, Length=286, Percent_Identity=34.6153846153846, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24642678, Length=263, Percent_Identity=33.4600760456274, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR003462 [H]

Pfam domain/function: PF02423 OCD_Mu_crystall [H]

EC number: =4.3.1.12 [H]

Molecular weight: Translated: 35432; Mature: 35432

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVISANEQRNLVNMNEVIEYAALALKEFSAERTITPIRGSLPFANEQNTALIMPSVAEG
CEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCHHHHH
LEALGVKIVTVVPQNKQIGKKTINGIVMLSDFQTGEPLALLEGSYLTMIRTGALSGVATK
HHHCCEEEEEEECCCHHHHHHHHCCEEEEECCCCCCCEEEECCCEEEEEECCCHHHHHHH
YLARHNAKTLCIIGTGEQAKGIAEAIFAVRDIEKVILYNRTEEKAYAFAQHIQEKFGKPA
HHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCE
YVYRDPNEAIREADIIVTTTNATTPVFSETLQKGVHVNAVGSFRPSMQELPSHAIAEANK
EEEECCHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCHHHCCCHHHHHCCC
VVVESKEAALDETGDLQVPIKEGLFKANAIHAELGQIISKEKAGRENDEEITIFKSVGLA
EEEECHHHHCCCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
VVDIIVAKYLYEKAVEQGMGNKIEF
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLVISANEQRNLVNMNEVIEYAALALKEFSAERTITPIRGSLPFANEQNTALIMPSVAEG
CEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCHHHHH
LEALGVKIVTVVPQNKQIGKKTINGIVMLSDFQTGEPLALLEGSYLTMIRTGALSGVATK
HHHCCEEEEEEECCCHHHHHHHHCCEEEEECCCCCCCEEEECCCEEEEEECCCHHHHHHH
YLARHNAKTLCIIGTGEQAKGIAEAIFAVRDIEKVILYNRTEEKAYAFAQHIQEKFGKPA
HHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCE
YVYRDPNEAIREADIIVTTTNATTPVFSETLQKGVHVNAVGSFRPSMQELPSHAIAEANK
EEEECCHHHHCCCCEEEEECCCCCHHHHHHHHCCCEEEEECCCCCCHHHCCCHHHHHCCC
VVVESKEAALDETGDLQVPIKEGLFKANAIHAELGQIISKEKAGRENDEEITIFKSVGLA
EEEECHHHHCCCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHH
VVDIIVAKYLYEKAVEQGMGNKIEF
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481432 [H]