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The map label for this gene is appB [H]

Identifier: 218234318

GI number: 218234318

Start: 918728

End: 919678

Strand: Direct

Name: appB [H]

Synonym: BCB4264_A0946

Alternate gene names: 218234318

Gene position: 918728-919678 (Clockwise)

Preceding gene: 218233727

Following gene: 218233551

Centisome position: 16.95

GC content: 35.86

Gene sequence:

>951_bases
GTGTATAAAGTAATTGCGAAGAGGCTTTTAAATGCAATTCCGCTTTTATTTGTTATTTCTATTATTTCTTTTCTATTAAT
AAAGCTAGCGCCGGGGGATCCCGTTCGAAACTTTGTAACGCCAAACATGAGTCCAATTGATGTGGAGCGTATTCGCAAAA
GTTTAGGACTAGATCAACCAATTTACGTACAGTATTTTTTATGGTTAAAAAACATTTTAACGGGAAATTTTGGTTACTCA
CTTCAAAATCATCGTCCTGTTTTGGAACTTATCACAGAAAGATTACCTGCAACAATTGGGTTAATGGGATCATCTTTACT
CGTCTCATTCGTAATCGCAATACCACTTGGACTATTTACAGGTGTGAAAAAGAATTCATTCTTTGACCGCATTGTAAACT
TTATTTCATACGTTGGTATTTCTATGCCGGTTTTCTGGTTTGCACTACTATTAGTCTACTTATTCTCTTTAAAATTGAAC
CTACTTCCGAGTATGGGTATGCGCACCGTAGGTAAAGATTCTGTTTGGGATATTGTGCAACACGGCATTTTACCTTGTAT
GGTGCTAGCGTTCCAAAACGTATCTGTTTATATGAGATATATTCGTTCAAGTACGATTCAGCAATTAGAAGAAGAATATG
TACAAATTCAATATGCGTACGGTGCTTCAAAGAAAACGGTGTTATTTAATCACGTACTTCGAAATGTATTAATACCGATC
ATTACAATTTTCGGATTATCGATTCCAAGTTTAGTAGGCGGAGCGTTTATTACGGAAACAGTATTTTCATGGCCGGGTCT
TGGTTCACTTGGAGTAAATGCTATTTTTAGATTTGATTATCCGATTATCATGGCAATTACATTACTATCATCATTCATGT
TAATTCTCGGTAACTTAATTGCTGATATTTTATATGGCGTAGTAGATCCGCGCATTCGAATGAGGGGGTGA

Upstream 100 bases:

>100_bases
GTCACAATGTTTGAAGATCTATCTAAGATTTATGAAGTGAAATAAGAAACAATAAAGAAGCTGGTGGAAATCAGCTTCTT
TAGCTTGAGGGGGGAAGTTT

Downstream 100 bases:

>100_bases
TTTGGAATGAATAATAGGAGATTTCAAACGATAAAAAGTAGTTTTACGAAAAATAAATTTGTACTAATGGGAGTTATAAT
ACTTGCGATTTTAACGGTTG

Product: oligopeptide ABC transporter, permease protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MYKVIAKRLLNAIPLLFVISIISFLLIKLAPGDPVRNFVTPNMSPIDVERIRKSLGLDQPIYVQYFLWLKNILTGNFGYS
LQNHRPVLELITERLPATIGLMGSSLLVSFVIAIPLGLFTGVKKNSFFDRIVNFISYVGISMPVFWFALLLVYLFSLKLN
LLPSMGMRTVGKDSVWDIVQHGILPCMVLAFQNVSVYMRYIRSSTIQQLEEEYVQIQYAYGASKKTVLFNHVLRNVLIPI
ITIFGLSIPSLVGGAFITETVFSWPGLGSLGVNAIFRFDYPIIMAITLLSSFMLILGNLIADILYGVVDPRIRMRG

Sequences:

>Translated_316_residues
MYKVIAKRLLNAIPLLFVISIISFLLIKLAPGDPVRNFVTPNMSPIDVERIRKSLGLDQPIYVQYFLWLKNILTGNFGYS
LQNHRPVLELITERLPATIGLMGSSLLVSFVIAIPLGLFTGVKKNSFFDRIVNFISYVGISMPVFWFALLLVYLFSLKLN
LLPSMGMRTVGKDSVWDIVQHGILPCMVLAFQNVSVYMRYIRSSTIQQLEEEYVQIQYAYGASKKTVLFNHVLRNVLIPI
ITIFGLSIPSLVGGAFITETVFSWPGLGSLGVNAIFRFDYPIIMAITLLSSFMLILGNLIADILYGVVDPRIRMRG
>Mature_316_residues
MYKVIAKRLLNAIPLLFVISIISFLLIKLAPGDPVRNFVTPNMSPIDVERIRKSLGLDQPIYVQYFLWLKNILTGNFGYS
LQNHRPVLELITERLPATIGLMGSSLLVSFVIAIPLGLFTGVKKNSFFDRIVNFISYVGISMPVFWFALLLVYLFSLKLN
LLPSMGMRTVGKDSVWDIVQHGILPCMVLAFQNVSVYMRYIRSSTIQQLEEEYVQIQYAYGASKKTVLFNHVLRNVLIPI
ITIFGLSIPSLVGGAFITETVFSWPGLGSLGVNAIFRFDYPIIMAITLLSSFMLILGNLIADILYGVVDPRIRMRG

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=315, Percent_Identity=38.7301587301587, Blast_Score=226, Evalue=1e-60,
Organism=Escherichia coli, GI1789888, Length=316, Percent_Identity=37.9746835443038, Blast_Score=221, Evalue=5e-59,
Organism=Escherichia coli, GI1789965, Length=338, Percent_Identity=34.3195266272189, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1787761, Length=335, Percent_Identity=34.6268656716418, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1787497, Length=316, Percent_Identity=30.379746835443, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1787550, Length=272, Percent_Identity=32.7205882352941, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1788504, Length=357, Percent_Identity=28.5714285714286, Blast_Score=137, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35550; Mature: 35550

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKVIAKRLLNAIPLLFVISIISFLLIKLAPGDPVRNFVTPNMSPIDVERIRKSLGLDQP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCH
IYVQYFLWLKNILTGNFGYSLQNHRPVLELITERLPATIGLMGSSLLVSFVIAIPLGLFT
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVKKNSFFDRIVNFISYVGISMPVFWFALLLVYLFSLKLNLLPSMGMRTVGKDSVWDIVQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
HGILPCMVLAFQNVSVYMRYIRSSTIQQLEEEYVQIQYAYGASKKTVLFNHVLRNVLIPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCHHHHHHHHHHHHHHHH
ITIFGLSIPSLVGGAFITETVFSWPGLGSLGVNAIFRFDYPIIMAITLLSSFMLILGNLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ADILYGVVDPRIRMRG
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MYKVIAKRLLNAIPLLFVISIISFLLIKLAPGDPVRNFVTPNMSPIDVERIRKSLGLDQP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHCCCCH
IYVQYFLWLKNILTGNFGYSLQNHRPVLELITERLPATIGLMGSSLLVSFVIAIPLGLFT
HHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVKKNSFFDRIVNFISYVGISMPVFWFALLLVYLFSLKLNLLPSMGMRTVGKDSVWDIVQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
HGILPCMVLAFQNVSVYMRYIRSSTIQQLEEEYVQIQYAYGASKKTVLFNHVLRNVLIPI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCHHHHHHHHHHHHHHHH
ITIFGLSIPSLVGGAFITETVFSWPGLGSLGVNAIFRFDYPIIMAITLLSSFMLILGNLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
ADILYGVVDPRIRMRG
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]