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The map label for this gene is galE [C]

Identifier: 218234305

GI number: 218234305

Start: 292040

End: 292987

Strand: Direct

Name: galE [C]

Synonym: BCB4264_A0323

Alternate gene names: 218234305

Gene position: 292040-292987 (Clockwise)

Preceding gene: 218235938

Following gene: 218231683

Centisome position: 5.39

GC content: 28.38

Gene sequence:

>948_bases
ATGAGGAAGAATAATTATTTAATAGTAGGTGGAAATAGTTTCATTGGTATCAACCTCGCATTGGGTTTATTGAAACAGGG
GCAAAATGTAAAAGTATTTTCCAGACATATAAATAATTTTCCTCAAAATATTGTAAGTGAAGTTGAATTTATTAAAGGTG
ATTTAAAAAATGTTGAGGATATATATAAGGCTTTAGTGAATATAGATATTATTATTTATTTAGCTGCGACGTCTAACGTA
GCAACTTCAATTGAAGATGTTTTCGGTGATATTAATAGCAGTCTATTTTTTCTTAATTTCATGGAAAGTGTTAAAGATTT
TCGTATTAAAAAAATTATATTAGCTTCTTCGGGAGGCACAGTTTATGGTGAACCTGAATATTTGCCTATTGATGAGAAAC
ATCCATTAAGACCACTTTCCCCGTATGGAATAACAAAAGTTTCGCTGGAGAATTATTTGTATTTTTATAAGAGAAAATAT
GGAATAGATTATGTTGTATGTAGATATTCTAATCCGTATGGAAAATACCAAAACCCCTTAAAAAAAGTTGGGGCGATAAA
TTGTTTTTTGTACCAGCATCTCAGTAATGAAAGGATTCATATATATGGGAATCCAGAGGAGATTATTAGAGATTATATTT
ATATCGATGATTTAGTTGAAATTACTATACAACTAGCACAATTAAATCAATTGAAATCTTGCGTATACAACATAGGGAGT
GGCAAAGGTCTTTCTTTAAAACGAATTATAGTGGAATTAGAGAAAATAACAGAAAGAAAAGTGGATTTTATCTGTTACAA
ACAAAAACAAGAGAACGTTCAAAAAATCATTTTAAATATTGATAAGATAAAACAAGAATTGAATTGGGAACCTAAAATAG
ATTTTAAACATGGGATTAGATTAAATAAGCTATGGATTGAAGAGTTCTTATATAGTAAAAAACAATAA

Upstream 100 bases:

>100_bases
ATACAATGATAAGAAGATGAATAATCGAAATGATCCAGTTTATTTGTGTATATTTTTAGGTTTGAAGACGGGAAAAATTT
ACTACTAGAGAGATGATATT

Downstream 100 bases:

>100_bases
CCCACACTCTACTTGTATAAGCAGAGTGTGGGTTATTATTTTACTTCTTTTTCTATAACCCAAAGGTCTTGATGTTCCCA
CCAAAATCCTTCAGTATACT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MRKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHINNFPQNIVSEVEFIKGDLKNVEDIYKALVNIDIIIYLAATSNV
ATSIEDVFGDINSSLFFLNFMESVKDFRIKKIILASSGGTVYGEPEYLPIDEKHPLRPLSPYGITKVSLENYLYFYKRKY
GIDYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNERIHIYGNPEEIIRDYIYIDDLVEITIQLAQLNQLKSCVYNIGS
GKGLSLKRIIVELEKITERKVDFICYKQKQENVQKIILNIDKIKQELNWEPKIDFKHGIRLNKLWIEEFLYSKKQ

Sequences:

>Translated_315_residues
MRKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHINNFPQNIVSEVEFIKGDLKNVEDIYKALVNIDIIIYLAATSNV
ATSIEDVFGDINSSLFFLNFMESVKDFRIKKIILASSGGTVYGEPEYLPIDEKHPLRPLSPYGITKVSLENYLYFYKRKY
GIDYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNERIHIYGNPEEIIRDYIYIDDLVEITIQLAQLNQLKSCVYNIGS
GKGLSLKRIIVELEKITERKVDFICYKQKQENVQKIILNIDKIKQELNWEPKIDFKHGIRLNKLWIEEFLYSKKQ
>Mature_315_residues
MRKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHINNFPQNIVSEVEFIKGDLKNVEDIYKALVNIDIIIYLAATSNV
ATSIEDVFGDINSSLFFLNFMESVKDFRIKKIILASSGGTVYGEPEYLPIDEKHPLRPLSPYGITKVSLENYLYFYKRKY
GIDYVVCRYSNPYGKYQNPLKKVGAINCFLYQHLSNERIHIYGNPEEIIRDYIYIDDLVEITIQLAQLNQLKSCVYNIGS
GKGLSLKRIIVELEKITERKVDFICYKQKQENVQKIILNIDKIKQELNWEPKIDFKHGIRLNKLWIEEFLYSKKQ

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=323, Percent_Identity=25.3869969040248, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI56118217, Length=323, Percent_Identity=25.3869969040248, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI189083684, Length=323, Percent_Identity=25.3869969040248, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI7657641, Length=329, Percent_Identity=24.9240121580547, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI42516563, Length=299, Percent_Identity=23.4113712374582, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI48994969, Length=340, Percent_Identity=24.4117647058824, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788353, Length=341, Percent_Identity=24.9266862170088, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982035, Length=335, Percent_Identity=24.7761194029851, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17539532, Length=300, Percent_Identity=22.3333333333333, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71982038, Length=337, Percent_Identity=24.3323442136499, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI115532424, Length=324, Percent_Identity=24.0740740740741, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6319493, Length=339, Percent_Identity=24.4837758112094, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI19923002, Length=326, Percent_Identity=25.7668711656442, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356223, Length=309, Percent_Identity=27.1844660194175, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36586; Mature: 36586

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHINNFPQNIVSEVEFIKGDLKNVED
CCCCCEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHH
IYKALVNIDIIIYLAATSNVATSIEDVFGDINSSLFFLNFMESVKDFRIKKIILASSGGT
HHHHHHCEEEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEECCCCE
VYGEPEYLPIDEKHPLRPLSPYGITKVSLENYLYFYKRKYGIDYVVCRYSNPYGKYQNPL
EECCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
KKVGAINCFLYQHLSNERIHIYGNPEEIIRDYIYIDDLVEITIQLAQLNQLKSCVYNIGS
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKGLSLKRIIVELEKITERKVDFICYKQKQENVQKIILNIDKIKQELNWEPKIDFKHGIR
CCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCC
LNKLWIEEFLYSKKQ
HHHHHHHHHHHCCCC
>Mature Secondary Structure
MRKNNYLIVGGNSFIGINLALGLLKQGQNVKVFSRHINNFPQNIVSEVEFIKGDLKNVED
CCCCCEEEEECCCEEEHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHH
IYKALVNIDIIIYLAATSNVATSIEDVFGDINSSLFFLNFMESVKDFRIKKIILASSGGT
HHHHHHCEEEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEECCCCE
VYGEPEYLPIDEKHPLRPLSPYGITKVSLENYLYFYKRKYGIDYVVCRYSNPYGKYQNPL
EECCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
KKVGAINCFLYQHLSNERIHIYGNPEEIIRDYIYIDDLVEITIQLAQLNQLKSCVYNIGS
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GKGLSLKRIIVELEKITERKVDFICYKQKQENVQKIILNIDKIKQELNWEPKIDFKHGIR
CCCCHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCC
LNKLWIEEFLYSKKQ
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]