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The map label for this gene is dhaK [H]

Identifier: 218233925

GI number: 218233925

Start: 988412

End: 990163

Strand: Direct

Name: dhaK [H]

Synonym: BCB4264_A1008

Alternate gene names: 218233925

Gene position: 988412-990163 (Clockwise)

Preceding gene: 218231524

Following gene: 218231587

Centisome position: 18.24

GC content: 42.18

Gene sequence:

>1752_bases
ATGAAAAAGATTATAAACAAACCAGAAACATTAGTAATGGAAATGTGCAACGGAATGGTTATGGCTCATCCAGAGCTTGA
GCTTTTGAAAAAATATAAAGTCATCAAGAAGAAAGAAATGAACGAAAACAAAGTAACGTTAATTAGTGGCGGCGGTAGTG
GTCATGAGCCGGCACATGCAGGATTAGTCGGAAAAGGAATGTTAGATGCGGCAGTGTGCGGAGATGTGTTTGCGTCACCT
TCACAAATTCAGGTATACCAAGCGATTAAAGAGACAGCTAGTAAAAAAGGTACGTTATTAATTATTAAAAATTATAGCGG
CGATATTATGAATTTCAAAAACGGTGCGCATTTAGCGACGGAAGATGGAATTGAAGTCGACTACGTAAAGGTGGACGATG
ATATTGCGGTAGAAGATAGCCTGTACACAGTAGGGCGCCGCGGCGTTGCGGGCGTTATTTTAGTTCATAAAATTGCTGGC
GCAGCAGCGGAAGAAGGTATGGATTTAGGAGCGGTGAAAGCTGTAGCAGAAAAAGCAGCGGCTAACGTGCGCACAATCGG
TTTAGCATTAACGTCTTGTACAGTTCCAGCGAGCGGATCACCTACTTTCACACTTGCGGAAGATGAAATGGAATACGGCG
TAGGTATTCACGGCGAACCAGGAATTAAGCGTGAAAAAATGCTGTCAGCAGATGAACTAGCGAACCGTATGACAAATGAT
CTTGTAAAAGATTTAGGAGTAAAAGATGGAGAAGAAATTGCGCTTCTAGTTAACGGTTTTGGCGGAACACCACTGCAAGA
ACTTTACTTATTTAACAACGCAGTTACGAGAGAACTAGCTGCAAGAAACATTAAAATTAATAGAGTATTCGTCGGTAACT
ATATGACAAGTATTGATATGGCTGGTATGTCTTTAACGGTAATGAAGTTAGATGAAGAGCTAAAAACATTACTATCAAAA
GAATGTAATACACCAGCGTTTAAAGTAGACGGTCCAGTTGAAAGTGTAGAGTACGTAAATGTACTTGAAGAGACAGAAGA
GAAGGAAGTTTCATTTGAACTAGAAACGGCGGAAGAACACGCTGTTATTAATGATAATGTTATTACATTAAACAACATGA
TTTATCTCGTTGATAAAATGAGCGACGTTATTATTAAAAATGAAGTACCGTTCTGTGAGCTAGATACGCATGCTGGTGAT
GGCGACTTCGGAATGAGTGTGGCAAAAGGATTTAAGCAGTTAAAACGTGAGTGGCATTCGATTGTAGAACAAGAGAACGT
AACGATCGGATCATTCCTTGACGGTTGTTCCATGATTATTATGGAACATTGCGGCGGCGCATCTGGTCCAATTTGGGGCG
GTGCATTCCGCGCAGCTAGTAAAGCAGCAGGCGAAAAACGTGAGCTAACAGTGAAAGAATTCGCTGAAATACTGCAAGCA
GCATTGCAAGGCATCCAATCGATCGGTGAAAGATCATTCGGCAGAGGAGCAGTAGTTGGTGACAAAACACTTGTTGACGC
ACTTGCTCCATGTGTAGATTCTTGGTTAGATAGCGCCTCAAACGAAGTAGACGTAAAAACTGCCTTTGAAAAAGGAGCAG
AAGCAGCGGTCAAAGGAGCAGAGTACACGAAAGAAATCGTAGCTCGCATGGGCCGCGCTGGTACAGTTGGCGAAAGAAGC
TTAGGATATCCAGATGCAGGTGCACATGCACTTGGGGTTATCTTTACGGAGATTGCGGGTAGTTTGAAATAG

Upstream 100 bases:

>100_bases
TTTGTCCGTTTACTATAAAACGCTTTCATTTTAACATGGTTAGTAAGAAGAAGATTTCAAATATATCACAATATATTAAA
GGAATTGAGGGAGAACTACA

Downstream 100 bases:

>100_bases
GAATTGGAAAGTCCCTCTGCCTTAAGGTGGAGGGATTTTTATATAGTTGATATGTAGAAGACTTCTTTCGGTTCTTTCTC
AGTAAAATATGAGTTTGTTA

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEEGMDLGAVKAVAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
LVKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDEELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEEHAVINDNVITLNNMIYLVDKMSDVIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEILQA
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLDSASNEVDVKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK

Sequences:

>Translated_583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEEGMDLGAVKAVAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
LVKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDEELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEEHAVINDNVITLNNMIYLVDKMSDVIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEILQA
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLDSASNEVDVKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK
>Mature_583_residues
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHAGLVGKGMLDAAVCGDVFASP
SQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLATEDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAG
AAAEEGMDLGAVKAVAEKAAANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
LVKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDMAGMSLTVMKLDEELKTLLSK
ECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEEHAVINDNVITLNNMIYLVDKMSDVIIKNEVPFCELDTHAGD
GDFGMSVAKGFKQLKREWHSIVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEILQA
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLDSASNEVDVKTAFEKGAEAAVKGAEYTKEIVARMGRAGTVGERS
LGYPDAGAHALGVIFTEIAGSLK

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=579, Percent_Identity=33.3333333333333, Blast_Score=285, Evalue=6e-77,
Organism=Escherichia coli, GI87081857, Length=353, Percent_Identity=40.5099150141643, Blast_Score=275, Evalue=6e-75,
Organism=Escherichia coli, GI1787449, Length=212, Percent_Identity=28.3018867924528, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565018, Length=581, Percent_Identity=31.1531841652324, Blast_Score=266, Evalue=2e-71,
Organism=Saccharomyces cerevisiae, GI6321055, Length=603, Percent_Identity=31.1774461028192, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6323570, Length=591, Percent_Identity=32.6565143824027, Blast_Score=209, Evalue=8e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 62452; Mature: 62452

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
GLVGKGMLDAAVCGDVFASPSQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLAT
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCEEC
EDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAGAAAEEGMDLGAVKAVAEKAA
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
CCHHEEEEEEEEEECCCCCCCCEEEECCCHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHH
LVKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDM
HHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHH
AGMSLTVMKLDEELKTLLSKECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEEH
CCCEEEEEHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCHHHEEEEEECCCCC
AVINDNVITLNNMIYLVDKMSDVIIKNEVPFCELDTHAGDGDFGMSVAKGFKQLKREWHS
EEECCCEEEECCEEEEEEHHHHHEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
IVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEILQA
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLDSASNEVDVKTAFEKGAEAAVKGA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCHHHHHHHH
EYTKEIVARMGRAGTVGERSLGYPDAGAHALGVIFTEIAGSLK
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKKIINKPETLVMEMCNGMVMAHPELELLKKYKVIKKKEMNENKVTLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCC
GLVGKGMLDAAVCGDVFASPSQIQVYQAIKETASKKGTLLIIKNYSGDIMNFKNGAHLAT
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCEEECCCCCCEEC
EDGIEVDYVKVDDDIAVEDSLYTVGRRGVAGVILVHKIAGAAAEEGMDLGAVKAVAEKAA
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ANVRTIGLALTSCTVPASGSPTFTLAEDEMEYGVGIHGEPGIKREKMLSADELANRMTND
CCHHEEEEEEEEEECCCCCCCCEEEECCCHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHH
LVKDLGVKDGEEIALLVNGFGGTPLQELYLFNNAVTRELAARNIKINRVFVGNYMTSIDM
HHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHHH
AGMSLTVMKLDEELKTLLSKECNTPAFKVDGPVESVEYVNVLEETEEKEVSFELETAEEH
CCCEEEEEHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHCCHHHEEEEEECCCCC
AVINDNVITLNNMIYLVDKMSDVIIKNEVPFCELDTHAGDGDFGMSVAKGFKQLKREWHS
EEECCCEEEECCEEEEEEHHHHHEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
IVEQENVTIGSFLDGCSMIIMEHCGGASGPIWGGAFRAASKAAGEKRELTVKEFAEILQA
HHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH
ALQGIQSIGERSFGRGAVVGDKTLVDALAPCVDSWLDSASNEVDVKTAFEKGAEAAVKGA
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHCCHHHHHHHH
EYTKEIVARMGRAGTVGERSLGYPDAGAHALGVIFTEIAGSLK
HHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]