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The map label for this gene is folB [H]

Identifier: 218233912

GI number: 218233912

Start: 78255

End: 78617

Strand: Direct

Name: folB [H]

Synonym: BCB4264_A0080

Alternate gene names: 218233912

Gene position: 78255-78617 (Clockwise)

Preceding gene: 218233849

Following gene: 218235679

Centisome position: 1.44

GC content: 37.19

Gene sequence:

>363_bases
TTGGATAAAATTTATATCCATGATATGGAGTTTTATGGTTATCATGGTGTGTTCCCAGAGGAGAATAAATTAGGTCAGAG
ATTTAAAGTTGACTTAACGGTGGAGTTGGATTTAAAGCGTGCAGGGGAAAGTGATGACTTAGAGCATTCGGTCAATTATG
GAGAGCTTTTCGAATTATGTAGAAAAGTTGTTGAGGATAGAAAGTATAAGCTTGTGGAGAGTATCGCTGAAAATATTGCT
GCAGATATATTAAAACAATATGAAAGTATTTCACGCTGTACAATTAAGGTAATTAAGCCGGATCCACCGATACCGGGTCA
TTATCGTGCTGTAGCAGTAGAAATTACGAGAGAACGTCCATGA

Upstream 100 bases:

>100_bases
TATTGAAAAGGGCTGTGAGTTTGTTCGTGTCCATGATGTGAAAGAAATGGCGCGTATGGCTAAAATGATGGATGCGATGA
TTGGTAAGGGGGTAAGGTAA

Downstream 100 bases:

>100_bases
ACAATATAGCTTACATTGCATTAGGGTCAAATATTGGAGAGCGTTATACGTATCTTACTGAAGCGATTCAGTTTTTAAAT
AAAAATCCTTATATTCAGGT

Product: dihydroneopterin aldolase

Products: NA

Alternate protein names: DHNA [H]

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKRAGESDDLEHSVNYGELFELCRKVVEDRKYKLVESIAENIA
ADILKQYESISRCTIKVIKPDPPIPGHYRAVAVEITRERP

Sequences:

>Translated_120_residues
MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKRAGESDDLEHSVNYGELFELCRKVVEDRKYKLVESIAENIA
ADILKQYESISRCTIKVIKPDPPIPGHYRAVAVEITRERP
>Mature_120_residues
MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKRAGESDDLEHSVNYGELFELCRKVVEDRKYKLVESIAENIA
ADILKQYESISRCTIKVIKPDPPIPGHYRAVAVEITRERP

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin [H]

COG id: COG1539

COG function: function code H; Dihydroneopterin aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHNA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006156
- InterPro:   IPR006157 [H]

Pfam domain/function: PF02152 FolB [H]

EC number: =4.1.2.25 [H]

Molecular weight: Translated: 13971; Mature: 13971

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKRAGESDDLEHSVNYGELFELC
CCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCHHCCCHHHHHHHH
RKVVEDRKYKLVESIAENIAADILKQYESISRCTIKVIKPDPPIPGHYRAVAVEITRERP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEEEEEEECCCC
>Mature Secondary Structure
MDKIYIHDMEFYGYHGVFPEENKLGQRFKVDLTVELDLKRAGESDDLEHSVNYGELFELC
CCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCHHCCCHHHHHHHH
RKVVEDRKYKLVESIAENIAADILKQYESISRCTIKVIKPDPPIPGHYRAVAVEITRERP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCEEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]