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The map label for this gene is tdcA [H]

Identifier: 218233817

GI number: 218233817

Start: 1810370

End: 1811242

Strand: Direct

Name: tdcA [H]

Synonym: BCB4264_A1903

Alternate gene names: 218233817

Gene position: 1810370-1811242 (Clockwise)

Preceding gene: 218232335

Following gene: 218235934

Centisome position: 33.41

GC content: 33.1

Gene sequence:

>873_bases
ATGAATGTTTTTGATTTTAAAGTCTTTACATATGTGGCTCGTTTAAATAGCATTAGTCTGGCAGCGAAGGAATTACATAT
GACACAGCCAGCAATAACACATATTATTAATAAATTAGAGAAACGATATGCTATAACGTTATTTGATCGCTCTAGACAAG
GAACGATTCTAACTGAACATGGAAAAGAATTTTTGGTTGGTGTGAATCGACTTCTAATGGAGTATGAAAAACTTGAGGAA
ACAGCTTTACAGTTGAAAAATAAAAGCTTGTATAAAATTGTACTAGCTACGTATCCTTCCGTTACTGTATATTGTTTGGC
GGAGTGTATTCAACTAGGGAATATTGATCATAGTCAATATGTACTTGCAGTTCGAGAAGGAAGCTATCAAGAAGTGTTAG
ATTGGCTATCATCAGGTAGTGCAGATTTTTCTATTTCTATAAAAGAAAATTTAATACAAGGATTTCATTATGATGTCATT
GGTGAAGATCCGTATGTTATGGTTTCTTCAAAAAAAGTTCCGCCTAACCTTACTATTAATGATATAAAAAATTATCCTTT
TATTATGCCGCTTTCTGGTTGCAAAGAAGTGCTCGAACCGTATTTGATGAAAAATGAAATAACAGTTAATAAAGTGATGG
AGTCAGAAACAATTAGTTCAGCATTAGCACTTACTATACAAGTTAATGGTATAACAATCGTCCCGTTATCAGGACTACAT
AAGCAAATTATTCATGACTTCATTGTACAGCCGATAGAAATTACAATTCCACGACAACTTATTATGCAATGGTCACCTAA
AAAAGAGAATGACCCGCTGTTTCTCGCGTTTGTTAAGAACTTATTAGCTCAACTACAGCAAAAGAAAAAATGA

Upstream 100 bases:

>100_bases
AATATTGATGATGTATACTCAGTATAAATGAAGTGGTTTTATAAATATAATGAAGGTTATTTATAGATGATATAAATATA
TTTTATATAAGGAGAACAGA

Downstream 100 bases:

>100_bases
ATATAATATTACAAAAGGTAAGCTCATTTCACTGAAGCTTATCTTTTGTATGTATTACCAATAAAGAGCGGTATCATAAA
GTCCGATTAATATAAGAAGA

Product: transcriptional regulator, LysR family, putative

Products: NA

Alternate protein names: Tdc operon transcriptional activator [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MNVFDFKVFTYVARLNSISLAAKELHMTQPAITHIINKLEKRYAITLFDRSRQGTILTEHGKEFLVGVNRLLMEYEKLEE
TALQLKNKSLYKIVLATYPSVTVYCLAECIQLGNIDHSQYVLAVREGSYQEVLDWLSSGSADFSISIKENLIQGFHYDVI
GEDPYVMVSSKKVPPNLTINDIKNYPFIMPLSGCKEVLEPYLMKNEITVNKVMESETISSALALTIQVNGITIVPLSGLH
KQIIHDFIVQPIEITIPRQLIMQWSPKKENDPLFLAFVKNLLAQLQQKKK

Sequences:

>Translated_290_residues
MNVFDFKVFTYVARLNSISLAAKELHMTQPAITHIINKLEKRYAITLFDRSRQGTILTEHGKEFLVGVNRLLMEYEKLEE
TALQLKNKSLYKIVLATYPSVTVYCLAECIQLGNIDHSQYVLAVREGSYQEVLDWLSSGSADFSISIKENLIQGFHYDVI
GEDPYVMVSSKKVPPNLTINDIKNYPFIMPLSGCKEVLEPYLMKNEITVNKVMESETISSALALTIQVNGITIVPLSGLH
KQIIHDFIVQPIEITIPRQLIMQWSPKKENDPLFLAFVKNLLAQLQQKKK
>Mature_290_residues
MNVFDFKVFTYVARLNSISLAAKELHMTQPAITHIINKLEKRYAITLFDRSRQGTILTEHGKEFLVGVNRLLMEYEKLEE
TALQLKNKSLYKIVLATYPSVTVYCLAECIQLGNIDHSQYVLAVREGSYQEVLDWLSSGSADFSISIKENLIQGFHYDVI
GEDPYVMVSSKKVPPNLTINDIKNYPFIMPLSGCKEVLEPYLMKNEITVNKVMESETISSALALTIQVNGITIVPLSGLH
KQIIHDFIVQPIEITIPRQLIMQWSPKKENDPLFLAFVKNLLAQLQQKKK

Specific function: Transcriptional activator for the tdcABCDE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789506, Length=270, Percent_Identity=24.8148148148148, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1788748, Length=268, Percent_Identity=22.0149253731343, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787601, Length=273, Percent_Identity=23.4432234432234, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI145693105, Length=291, Percent_Identity=23.7113402061856, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33035; Mature: 33035

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVFDFKVFTYVARLNSISLAAKELHMTQPAITHIINKLEKRYAITLFDRSRQGTILTEH
CCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEEECCCCCCEECCC
GKEFLVGVNRLLMEYEKLEETALQLKNKSLYKIVLATYPSVTVYCLAECIQLGNIDHSQY
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCHHHHHHHHHHHHCCCCCCCE
VLAVREGSYQEVLDWLSSGSADFSISIKENLIQGFHYDVIGEDPYVMVSSKKVPPNLTIN
EEEEECCCHHHHHHHHHCCCCCEEEEEHHHHHCCCCEEEECCCCEEEEECCCCCCCCCHH
DIKNYPFIMPLSGCKEVLEPYLMKNEITVNKVMESETISSALALTIQVNGITIVPLSGLH
CCCCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEEECCEEEEECCHHH
KQIIHDFIVQPIEITIPRQLIMQWSPKKENDPLFLAFVKNLLAQLQQKKK
HHHHHHHHCCCEEEECCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNVFDFKVFTYVARLNSISLAAKELHMTQPAITHIINKLEKRYAITLFDRSRQGTILTEH
CCEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEEEECCCCCCEECCC
GKEFLVGVNRLLMEYEKLEETALQLKNKSLYKIVLATYPSVTVYCLAECIQLGNIDHSQY
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCHHHHHHHHHHHHCCCCCCCE
VLAVREGSYQEVLDWLSSGSADFSISIKENLIQGFHYDVIGEDPYVMVSSKKVPPNLTIN
EEEEECCCHHHHHHHHHCCCCCEEEEEHHHHHCCCCEEEECCCCEEEEECCCCCCCCCHH
DIKNYPFIMPLSGCKEVLEPYLMKNEITVNKVMESETISSALALTIQVNGITIVPLSGLH
CCCCCCEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCEEEEEEEECCEEEEECCHHH
KQIIHDFIVQPIEITIPRQLIMQWSPKKENDPLFLAFVKNLLAQLQQKKK
HHHHHHHHCCCEEEECCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]