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The map label for this gene is blaR1 [H]

Identifier: 218233788

GI number: 218233788

Start: 1087911

End: 1089680

Strand: Direct

Name: blaR1 [H]

Synonym: BCB4264_A1111

Alternate gene names: 218233788

Gene position: 1087911-1089680 (Clockwise)

Preceding gene: 218231366

Following gene: 218232519

Centisome position: 20.08

GC content: 34.24

Gene sequence:

>1770_bases
ATGCTGTGGATCGTATTAATGATAAGACTCCTTTTACCGTGGTCGCCAGATAGCTCTTATAGCATTTACTCATTACTTTC
TTATAGTTCTAGCGTATCGGAAGTTATTCCAAAAAATATGCCGGCTACTGAGAATATAGTGAACATAGAAAGTGACCGAA
AAGTGGAATTGGAATCAAATTCTAAAATGGTGACAAAAACTAGCGAACCGGAAGTAAAAGTCAGTTCGGAAAAACAGACT
ACATTTTCTTTATACAAACTTGCTTTGTATGTGTGGCTAGCTGGGGTAATCATATTAGCAGCCATCACGTTTCTTACAAA
TAGACGTTTATATTCTTACATAAAGAAACAACCGGATATTACGGACGAACAGGTCACTACAGTGTTTAATCGCTGTAAGC
AGTCTATGAAAATGAAGAAGGCAGTTTCGTTACGTCTAGCGGGAAAGATTGCGAGCCCAACTGTGTTTAGTTTCTTTCGT
CCGAAAGTATTACTATCAAAAAAACATATGAAAGTATTAAATAAACAACAATTACAATATGTCTTTTACCATGAGTTAGC
TCATATTAAGAGAAACGATGTAGCTGTAAATTGGATTATGTACAGTTTAATCCTATTAAATTGGTTCAATCCGATTCTTT
GGTACGCCTATTTTTGTATGCGAGAAGATCAAGAATTAGCCTGTGATGCATATGCACTTACTTTTATAGATAAAGAGGAG
CAAATTGCATACGGACATACAATTATTACCCTTCTACAACACTATTCCTATCAAGTACCAAGCCTAGCAAATTTAAGTAG
AAATAAACGAACACTAAAAAGGAGAATCATTATGATTAAAAAATTCCAAAAGAAATCGTATCGTCTTTCTTTACTTGGGA
TTATTGCTATAGTTGCTATAGCATCCCTTTCTTTATTCAACGCACGTACAACGGAAGGAAAAGAAAAGCAAGAGGATAAA
GTAGAGCAGTCAAAGGATGCTTTCCAAAATGCTGTAGATACATTATTTGGTACAGAGGAAAAGGCGAGAAAAGAGTGGGG
AATGTCAAACTGGCAATATGAAAACCGAACAGCCTTTTTATATCATGCTGAAAAAGCTTTAACAAAGGAAGAGTTTGAGA
ATTATGTGCAGTTATATAAAGAGGTATTACAGATCGAGAAAAAAGGATTAGTTAGATTAAACTTACCCGAAAATTTCCAA
GGGGATATAAAAGAGGTGAAAGAAGAGCGCTTAAGTACAGAAAATCGTGAAAAATTAAAAGAAATTCGTAATAAAACAAC
TCCTTATGAGGATAAGGTAGGGAAGTATTTAACATATACAGTTGAAGAAGTGCAGCAACATGTTGATTTCCAAGTTAAGA
GGCCAACTTATACAATTAAAGGATATACCCAAAAAGACGAAAGGGTGAATTATTATCTTAAGATAAAGCCGGAATTCACT
ATTGAATTAGAATATACGAACGGAAAAGGAAATTATACAATTTCTCAATCGCAAGTTTTTGGGGAAAGCAAAGACCCATT
TAGCCACCAGTTTGTAGTGCCTGAAAATATAGAACAGTACGAACTAGAAGGGAATCAAATATTCTACGCTACTCATCACT
CGGATAGTAATTTACAAGGTATGAAGATGATTGTTCCAGCAAAAGGGAAAAATAGTGCATACCAAATCGTTATTATTAAT
CATAGTTTAGAGAACCAAGGAGAAGCAGTATTCGATAAGAATGTAAATAAAGAAGAATTAGAGAAAATTATGCTTTCTAT
GTTGAAATAG

Upstream 100 bases:

>100_bases
TTGGCTTATAGAAACGTCACTTATGGCTAGCATATTAGTCGGATTTATTTTATGTATAAAAGTTCTATTTAGAAATAAAT
TATCCCCCCGGTGGCAATAT

Downstream 100 bases:

>100_bases
CAAAAAGGTGTTCTTAAGATGTATATCTCTAGAACATCTTTTCCTTTTCTCTTTTCTTCTGATAAACTATGGACAGTATG
ATATAACTTGACTGGAATTT

Product: beta-lactamase regulatory protein 1; methicillin resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MLWIVLMIRLLLPWSPDSSYSIYSLLSYSSSVSEVIPKNMPATENIVNIESDRKVELESNSKMVTKTSEPEVKVSSEKQT
TFSLYKLALYVWLAGVIILAAITFLTNRRLYSYIKKQPDITDEQVTTVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFR
PKVLLSKKHMKVLNKQQLQYVFYHELAHIKRNDVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEE
QIAYGHTIITLLQHYSYQVPSLANLSRNKRTLKRRIIMIKKFQKKSYRLSLLGIIAIVAIASLSLFNARTTEGKEKQEDK
VEQSKDAFQNAVDTLFGTEEKARKEWGMSNWQYENRTAFLYHAEKALTKEEFENYVQLYKEVLQIEKKGLVRLNLPENFQ
GDIKEVKEERLSTENREKLKEIRNKTTPYEDKVGKYLTYTVEEVQQHVDFQVKRPTYTIKGYTQKDERVNYYLKIKPEFT
IELEYTNGKGNYTISQSQVFGESKDPFSHQFVVPENIEQYELEGNQIFYATHHSDSNLQGMKMIVPAKGKNSAYQIVIIN
HSLENQGEAVFDKNVNKEELEKIMLSMLK

Sequences:

>Translated_589_residues
MLWIVLMIRLLLPWSPDSSYSIYSLLSYSSSVSEVIPKNMPATENIVNIESDRKVELESNSKMVTKTSEPEVKVSSEKQT
TFSLYKLALYVWLAGVIILAAITFLTNRRLYSYIKKQPDITDEQVTTVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFR
PKVLLSKKHMKVLNKQQLQYVFYHELAHIKRNDVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEE
QIAYGHTIITLLQHYSYQVPSLANLSRNKRTLKRRIIMIKKFQKKSYRLSLLGIIAIVAIASLSLFNARTTEGKEKQEDK
VEQSKDAFQNAVDTLFGTEEKARKEWGMSNWQYENRTAFLYHAEKALTKEEFENYVQLYKEVLQIEKKGLVRLNLPENFQ
GDIKEVKEERLSTENREKLKEIRNKTTPYEDKVGKYLTYTVEEVQQHVDFQVKRPTYTIKGYTQKDERVNYYLKIKPEFT
IELEYTNGKGNYTISQSQVFGESKDPFSHQFVVPENIEQYELEGNQIFYATHHSDSNLQGMKMIVPAKGKNSAYQIVIIN
HSLENQGEAVFDKNVNKEELEKIMLSMLK
>Mature_589_residues
MLWIVLMIRLLLPWSPDSSYSIYSLLSYSSSVSEVIPKNMPATENIVNIESDRKVELESNSKMVTKTSEPEVKVSSEKQT
TFSLYKLALYVWLAGVIILAAITFLTNRRLYSYIKKQPDITDEQVTTVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFR
PKVLLSKKHMKVLNKQQLQYVFYHELAHIKRNDVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEE
QIAYGHTIITLLQHYSYQVPSLANLSRNKRTLKRRIIMIKKFQKKSYRLSLLGIIAIVAIASLSLFNARTTEGKEKQEDK
VEQSKDAFQNAVDTLFGTEEKARKEWGMSNWQYENRTAFLYHAEKALTKEEFENYVQLYKEVLQIEKKGLVRLNLPENFQ
GDIKEVKEERLSTENREKLKEIRNKTTPYEDKVGKYLTYTVEEVQQHVDFQVKRPTYTIKGYTQKDERVNYYLKIKPEFT
IELEYTNGKGNYTISQSQVFGESKDPFSHQFVVPENIEQYELEGNQIFYATHHSDSNLQGMKMIVPAKGKNSAYQIVIIN
HSLENQGEAVFDKNVNKEELEKIMLSMLK

Specific function: BlaR1 is a potential penicillin-binding protein required for induction of beta-lactamase in Bacillus licheniformis [H]

COG id: COG4219

COG function: function code KT; Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001460
- InterPro:   IPR008756 [H]

Pfam domain/function: PF05569 Peptidase_M56; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 68835; Mature: 68835

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWIVLMIRLLLPWSPDSSYSIYSLLSYSSSVSEVIPKNMPATENIVNIESDRKVELESN
CHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHCCCCCCCCCCEEECCCCCEEEECCC
SKMVTKTSEPEVKVSSEKQTTFSLYKLALYVWLAGVIILAAITFLTNRRLYSYIKKQPDI
CEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TDEQVTTVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFRPKVLLSKKHMKVLNKQQLQY
CHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
VFYHELAHIKRNDVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCEEEEEEECCCC
QIAYGHTIITLLQHYSYQVPSLANLSRNKRTLKRRIIMIKKFQKKSYRLSLLGIIAIVAI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLSLFNARTTEGKEKQEDKVEQSKDAFQNAVDTLFGTEEKARKEWGMSNWQYENRTAFL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEECCCEEEE
YHAEKALTKEEFENYVQLYKEVLQIEKKGLVRLNLPENFQGDIKEVKEERLSTENREKLK
EECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHH
EIRNKTTPYEDKVGKYLTYTVEEVQQHVDFQVKRPTYTIKGYTQKDERVNYYLKIKPEFT
HHHHCCCCCHHHCCHHHHHHHHHHHHHCCEEEECCEEEEECCCCCCCCEEEEEEECCCEE
IELEYTNGKGNYTISQSQVFGESKDPFSHQFVVPENIEQYELEGNQIFYATHHSDSNLQG
EEEEEECCCCCEEEEHHHHCCCCCCCCCCEEECCCCCCCEEECCCEEEEEEECCCCCCCC
MKMIVPAKGKNSAYQIVIINHSLENQGEAVFDKNVNKEELEKIMLSMLK
EEEEEECCCCCCEEEEEEEECCCCCCCCEECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLWIVLMIRLLLPWSPDSSYSIYSLLSYSSSVSEVIPKNMPATENIVNIESDRKVELESN
CHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHHHCCCCCCCCCCEEECCCCCEEEECCC
SKMVTKTSEPEVKVSSEKQTTFSLYKLALYVWLAGVIILAAITFLTNRRLYSYIKKQPDI
CEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
TDEQVTTVFNRCKQSMKMKKAVSLRLAGKIASPTVFSFFRPKVLLSKKHMKVLNKQQLQY
CHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
VFYHELAHIKRNDVAVNWIMYSLILLNWFNPILWYAYFCMREDQELACDAYALTFIDKEE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCEEEEEEECCCC
QIAYGHTIITLLQHYSYQVPSLANLSRNKRTLKRRIIMIKKFQKKSYRLSLLGIIAIVAI
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASLSLFNARTTEGKEKQEDKVEQSKDAFQNAVDTLFGTEEKARKEWGMSNWQYENRTAFL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEECCCEEEE
YHAEKALTKEEFENYVQLYKEVLQIEKKGLVRLNLPENFQGDIKEVKEERLSTENREKLK
EECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHCCCHHHHHH
EIRNKTTPYEDKVGKYLTYTVEEVQQHVDFQVKRPTYTIKGYTQKDERVNYYLKIKPEFT
HHHHCCCCCHHHCCHHHHHHHHHHHHHCCEEEECCEEEEECCCCCCCCEEEEEEECCCEE
IELEYTNGKGNYTISQSQVFGESKDPFSHQFVVPENIEQYELEGNQIFYATHHSDSNLQG
EEEEEECCCCCEEEEHHHHCCCCCCCCCCEEECCCCCCCEEECCCEEEEEEECCCCCCCC
MKMIVPAKGKNSAYQIVIINHSLENQGEAVFDKNVNKEELEKIMLSMLK
EEEEEECCCCCCEEEEEEEECCCCCCCCEECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3040663; 3260234; 2404938 [H]