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The map label for this gene is atoS [H]

Identifier: 218233711

GI number: 218233711

Start: 1447308

End: 1448579

Strand: Reverse

Name: atoS [H]

Synonym: BCB4264_A1513

Alternate gene names: 218233711

Gene position: 1448579-1447308 (Counterclockwise)

Preceding gene: 218234177

Following gene: 218234475

Centisome position: 26.73

GC content: 31.6

Gene sequence:

>1272_bases
ATGCTTCCAAACGATGCTACTGTATCTCATGAAAAACGAATTGAAGAACTAGAAAATAAAGTACGTTTTTATGAAGAACT
TGTGAATCAATTACCACATCATTTCACATACAAAAATCCACATATTGGTTTACGAATAAAGAAAACTAGAACAACCCATT
CCATTCAAGAAATACCAAAAGAAAATAAAGAGGCTCATTTTCAACTTACTTGTGATTCATTATTTTTATTTGAACAACTC
GAAAAACACTTTGTACATATTTTTGATGCCTTTTCACATCATGTAACCTTTGTCGATAGTAAAGGGAATATTACTTTATG
TAATCAAGTTGCTGCAGATGATTTCGGTGTAATACGAAATGATATTATCGGAAAACCGATTCAACAATTACTAAACTTGC
CGGAAGAAAAAATTAAAGCGATTGAAACATTAAAAACGGGAACAGAAATATATAATGAAGAAGTTTTAGACAAAAACTAT
GGCATTATAAATAACCGAATTATTCGTGATTATAACGGGGAGATTTTTAGAGTTATTAGTGTCTTTCATTATTTAAATAC
AGAACGTGATGCAGAGAAGTTTTCGTTAGCAGGGCGAATCGCAGCTGGAATTGCACACGAAGTACGAAATCCTCTTACAA
CAGTACGAGGATACTTACAATTTTTACAAGAAAGCGTTTCTCCATCAAATAAAGAGTTATTTAAAAATTTGCTTATCCCT
GAATTAGATCGTGCAAATAATATTATTACAAAATTTTTAGCCATTTCAAAAACACGGGAATTTACAAGAGAACCGTTTCC
CATTAATACATTTTTACGTGACTATATTCAACAGTTACTAGTTAGTGAAGTTTCCTTGCATAATATTTCAATTGATTATA
ACTTCTCTAATGAATTAGATGATATTTTAGTCAATATTGATCGACATGAACTTGTTCAAGTGTTTTTAAATCTATTTCAA
AATGCCGTCGATGCTCAAGGCGACAAACCTCTTTCTATTCAAATTACTAGTTATCGCCTTGATAACTTCGTTCGGATTAC
TTTCACAGATAATGGAATTGGTATTCCTCCAGCTATTCAAGAATATATCTTTGATCCATTCTTCTCAACGAAGGATTCGG
GAACAGGACTAGGCTTGTCAGTAACAAAAAAAATCATCCAAAATCATAACGGCACGCTCAAAATGACTAGTGCTTCAAAC
GGTACAACTTTCACTATTTCTATTCCAATCTTACCTAAAACAACCCTTGAAAAATTAAATCAATGTAAATAA

Upstream 100 bases:

>100_bases
TCCAAACACTTTGCATCATGTAGCCTTTTCTTTAAGAGTATCCTTATAAAAATATGATATACTATATGGAAGAATTTTTA
AAATGAGGGGTTATTTATTT

Downstream 100 bases:

>100_bases
AGGACTAATCCACGAACTACATGCCAATTGTTAAACACTCCCAACAATTAGCATGTAGTTTTTTATGTTGCACTTTTCTT
CTTTACATTATATAAACCTT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MLPNDATVSHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLRIKKTRTTHSIQEIPKENKEAHFQLTCDSLFLFEQL
EKHFVHIFDAFSHHVTFVDSKGNITLCNQVAADDFGVIRNDIIGKPIQQLLNLPEEKIKAIETLKTGTEIYNEEVLDKNY
GIINNRIIRDYNGEIFRVISVFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQESVSPSNKELFKNLLIP
ELDRANNIITKFLAISKTREFTREPFPINTFLRDYIQQLLVSEVSLHNISIDYNFSNELDDILVNIDRHELVQVFLNLFQ
NAVDAQGDKPLSIQITSYRLDNFVRITFTDNGIGIPPAIQEYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSASN
GTTFTISIPILPKTTLEKLNQCK

Sequences:

>Translated_423_residues
MLPNDATVSHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLRIKKTRTTHSIQEIPKENKEAHFQLTCDSLFLFEQL
EKHFVHIFDAFSHHVTFVDSKGNITLCNQVAADDFGVIRNDIIGKPIQQLLNLPEEKIKAIETLKTGTEIYNEEVLDKNY
GIINNRIIRDYNGEIFRVISVFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQESVSPSNKELFKNLLIP
ELDRANNIITKFLAISKTREFTREPFPINTFLRDYIQQLLVSEVSLHNISIDYNFSNELDDILVNIDRHELVQVFLNLFQ
NAVDAQGDKPLSIQITSYRLDNFVRITFTDNGIGIPPAIQEYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSASN
GTTFTISIPILPKTTLEKLNQCK
>Mature_423_residues
MLPNDATVSHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLRIKKTRTTHSIQEIPKENKEAHFQLTCDSLFLFEQL
EKHFVHIFDAFSHHVTFVDSKGNITLCNQVAADDFGVIRNDIIGKPIQQLLNLPEEKIKAIETLKTGTEIYNEEVLDKNY
GIINNRIIRDYNGEIFRVISVFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQESVSPSNKELFKNLLIP
ELDRANNIITKFLAISKTREFTREPFPINTFLRDYIQQLLVSEVSLHNISIDYNFSNELDDILVNIDRHELVQVFLNLFQ
NAVDAQGDKPLSIQITSYRLDNFVRITFTDNGIGIPPAIQEYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSASN
GTTFTISIPILPKTTLEKLNQCK

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=343, Percent_Identity=32.0699708454811, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1790436, Length=222, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790300, Length=353, Percent_Identity=26.3456090651558, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788393, Length=219, Percent_Identity=26.4840182648402, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1789149, Length=243, Percent_Identity=26.3374485596708, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=273, Percent_Identity=26.3736263736264, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=258, Percent_Identity=24.031007751938, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1786600, Length=346, Percent_Identity=24.2774566473988, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI48994928, Length=218, Percent_Identity=25.2293577981651, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786783, Length=247, Percent_Identity=27.9352226720648, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=23.5537190082645, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48534; Mature: 48534

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPNDATVSHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLRIKKTRTTHSIQEIPK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHCCC
ENKEAHFQLTCDSLFLFEQLEKHFVHIFDAFSHHVTFVDSKGNITLCNQVAADDFGVIRN
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECHHHCCHHHHHHH
DIIGKPIQQLLNLPEEKIKAIETLKTGTEIYNEEVLDKNYGIINNRIIRDYNGEIFRVIS
HHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHH
VFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQESVSPSNKELFKNLLIP
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
ELDRANNIITKFLAISKTREFTREPFPINTFLRDYIQQLLVSEVSLHNISIDYNFSNELD
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHH
DILVNIDRHELVQVFLNLFQNAVDAQGDKPLSIQITSYRLDNFVRITFTDNGIGIPPAIQ
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCEEEEEEECCCCCCCHHHH
EYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSASNGTTFTISIPILPKTTLEKLN
HHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCHHHHHHHH
QCK
CCC
>Mature Secondary Structure
MLPNDATVSHEKRIEELENKVRFYEELVNQLPHHFTYKNPHIGLRIKKTRTTHSIQEIPK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHCCC
ENKEAHFQLTCDSLFLFEQLEKHFVHIFDAFSHHVTFVDSKGNITLCNQVAADDFGVIRN
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECHHHCCHHHHHHH
DIIGKPIQQLLNLPEEKIKAIETLKTGTEIYNEEVLDKNYGIINNRIIRDYNGEIFRVIS
HHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCHHHHHHH
VFHYLNTERDAEKFSLAGRIAAGIAHEVRNPLTTVRGYLQFLQESVSPSNKELFKNLLIP
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
ELDRANNIITKFLAISKTREFTREPFPINTFLRDYIQQLLVSEVSLHNISIDYNFSNELD
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHH
DILVNIDRHELVQVFLNLFQNAVDAQGDKPLSIQITSYRLDNFVRITFTDNGIGIPPAIQ
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCEEEEEEECCCCCCCHHHH
EYIFDPFFSTKDSGTGLGLSVTKKIIQNHNGTLKMTSASNGTTFTISIPILPKTTLEKLN
HHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECCCCEEEEEEEECCCHHHHHHHH
QCK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]