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The map label for this gene is dapG2 [H]

Identifier: 218233377

GI number: 218233377

Start: 3817282

End: 3818514

Strand: Reverse

Name: dapG2 [H]

Synonym: BCB4264_A3898

Alternate gene names: 218233377

Gene position: 3818514-3817282 (Counterclockwise)

Preceding gene: 218232673

Following gene: 218231209

Centisome position: 70.46

GC content: 38.52

Gene sequence:

>1233_bases
ATGAAAATAATTGTTCAAAAATTTGGTGGCACATCAGTACGTGATGACAATGGACGTAAGCATGCGCTTCATCATATAAA
AAAATCATTAGCTGCTGGTTATAAAGTAGTTACTGTCGTATCTGCTATGGGCCGTAAAGGTGAACCATATGCAACGGATA
CGTTATTAAGTCTTGTAAATCAAGAGGAATCTACTATTTCTAAGCGTGAGCAAGATTTATTATTATCGTGTGGAGAGTTA
ATCTCTGCAATTGTTTTCTCTAATATGTTGAATGAGAATGGTATAAAAGCAGCAGCATTAAATGGTGCACAAGCTGGTTT
TGTAACGAATGATGACTTTACGAATGCAAAGATTATTGAAATGAATTGCGATCGTATACATGAAGAGTTAGAAAATGTAG
ATGTAATCGTCGTTACAGGATTCCAGGGACAAACGAAAAAAGGTGATACGACAACACTTGGACGCGGAGGTAGTGATACT
TCAGCTTCAGCATTAGGTGTTGCACTTCATGCTGAATACATCGATATATTCACTGATGTAGAAGGTGTTATGACTGCGGA
TCCTCGTATTGTAAAAGATGCACGTCATCTTCAAACTGTAACGTATAACGAAATTTGTAACATGGCTTATCAAGGTGCGA
AAGTCGTTCATCCACGTGCAGTTGAAATTGCGATGCATGCAAAAGTGCCACTTCGTGTACGTTCTACGTATTCTGATAGT
GAAGGTACGCTTATTTCAGCATATGACGGTGCTACAAGAGGTCGTGATGTAGAAGAACGTCCTGTTACAGGCATTGCCCA
CGTATCAAACGTAACGCAAATTAAAGTGCTTGCAAAAGAAACGGCATATGATTTGCAACAACATGTGTTTAAAGAGATGG
CGAACGAAGGAATAAGTGTTGATTTAATTAATATTTCACCTACTGGCGTAGCATATACGGTGAGTGATAATGTATCAAGT
CATGCAGTTAAATTATTACAGAACCTTGGATATGAGCCAATTGTGACAGAACATTGTGCGAAAGTATCTATTGTTGGGGC
TGGAATGGCAGGATACCCAGGGGTTACTGCGAAAATCGTTACAGCTTTAGCGGAAAAAGGTATTCAAATCCTGCAATCGG
CAGATAGTCATACAACAATTTGGGTTCTTGTAAAAGAAACTGATTTAGTGGAGGCTGTAAATGCATTACATAGTGCGTTT
GAGCTTTCAAAAGAAAAGCAACTGGAACAATAA

Upstream 100 bases:

>100_bases
CTGATAACTTATTAAAAGGCGCTGCATGGAATTCTGTTCAAATTGCAGAGCGCTTAGTAAAATTACAATTAGTGTAAACG
GCTAAGAGAAGGTGCAAAAT

Downstream 100 bases:

>100_bases
GGAGTGAGACCATGATAGATTTTGGGACAATTGCAACCGCGATGGTAACACCGTTTGATATAAACGGGAATATCGATTTT
GCAAAGACAACGAAATTGGT

Product: aspartate kinase I

Products: NA

Alternate protein names: Aspartate kinase 1; Aspartokinase I [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MKIIVQKFGGTSVRDDNGRKHALHHIKKSLAAGYKVVTVVSAMGRKGEPYATDTLLSLVNQEESTISKREQDLLLSCGEL
ISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIEMNCDRIHEELENVDVIVVTGFQGQTKKGDTTTLGRGGSDT
SASALGVALHAEYIDIFTDVEGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
EGTLISAYDGATRGRDVEERPVTGIAHVSNVTQIKVLAKETAYDLQQHVFKEMANEGISVDLINISPTGVAYTVSDNVSS
HAVKLLQNLGYEPIVTEHCAKVSIVGAGMAGYPGVTAKIVTALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAF
ELSKEKQLEQ

Sequences:

>Translated_410_residues
MKIIVQKFGGTSVRDDNGRKHALHHIKKSLAAGYKVVTVVSAMGRKGEPYATDTLLSLVNQEESTISKREQDLLLSCGEL
ISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIEMNCDRIHEELENVDVIVVTGFQGQTKKGDTTTLGRGGSDT
SASALGVALHAEYIDIFTDVEGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
EGTLISAYDGATRGRDVEERPVTGIAHVSNVTQIKVLAKETAYDLQQHVFKEMANEGISVDLINISPTGVAYTVSDNVSS
HAVKLLQNLGYEPIVTEHCAKVSIVGAGMAGYPGVTAKIVTALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAF
ELSKEKQLEQ
>Mature_410_residues
MKIIVQKFGGTSVRDDNGRKHALHHIKKSLAAGYKVVTVVSAMGRKGEPYATDTLLSLVNQEESTISKREQDLLLSCGEL
ISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIEMNCDRIHEELENVDVIVVTGFQGQTKKGDTTTLGRGGSDT
SASALGVALHAEYIDIFTDVEGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
EGTLISAYDGATRGRDVEERPVTGIAHVSNVTQIKVLAKETAYDLQQHVFKEMANEGISVDLINISPTGVAYTVSDNVSS
HAVKLLQNLGYEPIVTEHCAKVSIVGAGMAGYPGVTAKIVTALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAF
ELSKEKQLEQ

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartokinase family [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=279, Percent_Identity=34.4086021505376, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1790455, Length=347, Percent_Identity=31.1239193083574, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790376, Length=169, Percent_Identity=31.9526627218935, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6320893, Length=393, Percent_Identity=26.972010178117, Blast_Score=127, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 44217; Mature: 44217

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: PS00324 ASPARTOKINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIVQKFGGTSVRDDNGRKHALHHIKKSLAAGYKVVTVVSAMGRKGEPYATDTLLSLVN
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHC
QEESTISKREQDLLLSCGELISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCCCCEEEE
MNCDRIHEELENVDVIVVTGFQGQTKKGDTTTLGRGGSDTSASALGVALHAEYIDIFTDV
ECHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
EGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEECCCCEEEECCCCCC
EGTLISAYDGATRGRDVEERPVTGIAHVSNVTQIKVLAKETAYDLQQHVFKEMANEGISV
CCCEEEECCCCCCCCCCCCCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEE
DLINISPTGVAYTVSDNVSSHAVKLLQNLGYEPIVTEHCAKVSIVGAGMAGYPGVTAKIV
EEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCCCCCHHHHHH
TALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAFELSKEKQLEQ
HHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIIVQKFGGTSVRDDNGRKHALHHIKKSLAAGYKVVTVVSAMGRKGEPYATDTLLSLVN
CEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHC
QEESTISKREQDLLLSCGELISAIVFSNMLNENGIKAAALNGAQAGFVTNDDFTNAKIIE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEECCCCCCCEEEE
MNCDRIHEELENVDVIVVTGFQGQTKKGDTTTLGRGGSDTSASALGVALHAEYIDIFTDV
ECHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
EGVMTADPRIVKDARHLQTVTYNEICNMAYQGAKVVHPRAVEIAMHAKVPLRVRSTYSDS
CCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEEEECCCCEEEECCCCCC
EGTLISAYDGATRGRDVEERPVTGIAHVSNVTQIKVLAKETAYDLQQHVFKEMANEGISV
CCCEEEECCCCCCCCCCCCCCCCHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEE
DLINISPTGVAYTVSDNVSSHAVKLLQNLGYEPIVTEHCAKVSIVGAGMAGYPGVTAKIV
EEEEECCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHHCCEEEEEECCCCCCCCHHHHHH
TALAEKGIQILQSADSHTTIWVLVKETDLVEAVNALHSAFELSKEKQLEQ
HHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377 [H]