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The map label for this gene is asd2 [H]

Identifier: 218232673

GI number: 218232673

Start: 3818538

End: 3819584

Strand: Reverse

Name: asd2 [H]

Synonym: BCB4264_A3899

Alternate gene names: 218232673

Gene position: 3819584-3818538 (Counterclockwise)

Preceding gene: 218235343

Following gene: 218233377

Centisome position: 70.48

GC content: 37.54

Gene sequence:

>1047_bases
ATGGAAAAGCAAAAAACTTTTCATGTCGCTGTAGTTGGAGCAACCGGCGCAGTTGGTGAACAAATGTTAAATACTTTAGA
GAAACGAGAATTTCCAATCGGGAAATTAACGTTACTTTCATCTAAACGATCTGCAGGTAAGAAACTTGTATTTAAAGGCG
AAGAATTTACAGTTCAAGAGGCAACTCCTGAAAGCTTTGAAGGAGTAGATATTGCACTATTTAGTGCTGGTGGATCTGTA
TCGAAACAATTAGCGCCAGAAGCAGCAAAACGCGGTGCGATTGTTGTTGATAATACAAGTGCATTCCGTATGACAGAAAA
CGTGCCACTTGTTGTACCTGAAGTAAATGAAAACGACTTAAAAGAACATAATGGTATTATTGCAAATCCAAACTGTTCTA
CAATTCAAATGGTAGTAGCTCTTGAGCCAGTTCGTCAGCAATATGGTTTAAAACGAGTAATCGTTTCCACATATCAAGCT
GTATCAGGTGCTGGTGCGGCAGCTATTGAAGAACTGCATGAACAATCACAAGCAATCTTAAATGGCGAAGAAGTTAAGGC
AAATGTTCTTCCTGTATCAGGTGATAAGAAGCATTTCCCAATTGCTTTTAATGCGATTCCACAGATTGATAAATTCCAAG
ATAATGGATTTACGTTTGAAGAAATGAAAATGATTAACGAAACGAAAAAAATTATGCATATGCCTGAATTAGAAGTAGCG
GCAACATGTGTACGTTTACCAGTTGTATCAGGACACTCTGAGTCTGTTTACATCGAAGTAGAAAAAGAAGGCGTAACAGT
AGCAGAATTAAAGAGCTTACTTGCAAATGCGGAAGGTATTGTTCTGCAAGATAATCCAGAAGAGCAGTTATATCCAATGC
CAGCTACTGCAGTAGGTAAAAACGAAGTATTCGTTGGAAGAATCCGTAAAGATTTAAATAACGATAAAGGATTCCATCTT
TGGGTCGTATCTGATAACTTATTAAAAGGCGCTGCATGGAATTCTGTTCAAATTGCAGAGCGCTTAGTAAAATTACAATT
AGTGTAA

Upstream 100 bases:

>100_bases
GAATATGATAAAATTAACGTTATTAAGATTAGAAGGGGTATTGTATACTCCTTCTGATTCTAAGTTATAGAAGGATTGGT
ATCTAGAAAGGGGCATAGTG

Downstream 100 bases:

>100_bases
ACGGCTAAGAGAAGGTGCAAAATATGAAAATAATTGTTCAAAAATTTGGTGGCACATCAGTACGTGATGACAATGGACGT
AAGCATGCGCTTCATCATAT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MEKQKTFHVAVVGATGAVGEQMLNTLEKREFPIGKLTLLSSKRSAGKKLVFKGEEFTVQEATPESFEGVDIALFSAGGSV
SKQLAPEAAKRGAIVVDNTSAFRMTENVPLVVPEVNENDLKEHNGIIANPNCSTIQMVVALEPVRQQYGLKRVIVSTYQA
VSGAGAAAIEELHEQSQAILNGEEVKANVLPVSGDKKHFPIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELEVA
ATCVRLPVVSGHSESVYIEVEKEGVTVAELKSLLANAEGIVLQDNPEEQLYPMPATAVGKNEVFVGRIRKDLNNDKGFHL
WVVSDNLLKGAAWNSVQIAERLVKLQLV

Sequences:

>Translated_348_residues
MEKQKTFHVAVVGATGAVGEQMLNTLEKREFPIGKLTLLSSKRSAGKKLVFKGEEFTVQEATPESFEGVDIALFSAGGSV
SKQLAPEAAKRGAIVVDNTSAFRMTENVPLVVPEVNENDLKEHNGIIANPNCSTIQMVVALEPVRQQYGLKRVIVSTYQA
VSGAGAAAIEELHEQSQAILNGEEVKANVLPVSGDKKHFPIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELEVA
ATCVRLPVVSGHSESVYIEVEKEGVTVAELKSLLANAEGIVLQDNPEEQLYPMPATAVGKNEVFVGRIRKDLNNDKGFHL
WVVSDNLLKGAAWNSVQIAERLVKLQLV
>Mature_348_residues
MEKQKTFHVAVVGATGAVGEQMLNTLEKREFPIGKLTLLSSKRSAGKKLVFKGEEFTVQEATPESFEGVDIALFSAGGSV
SKQLAPEAAKRGAIVVDNTSAFRMTENVPLVVPEVNENDLKEHNGIIANPNCSTIQMVVALEPVRQQYGLKRVIVSTYQA
VSGAGAAAIEELHEQSQAILNGEEVKANVLPVSGDKKHFPIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELEVA
ATCVRLPVVSGHSESVYIEVEKEGVTVAELKSLLANAEGIVLQDNPEEQLYPMPATAVGKNEVFVGRIRKDLNNDKGFHL
WVVSDNLLKGAAWNSVQIAERLVKLQLV

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=345, Percent_Identity=34.4927536231884, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1789841, Length=357, Percent_Identity=29.9719887955182, Blast_Score=112, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6320362, Length=396, Percent_Identity=27.2727272727273, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37974; Mature: 37974

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01103 ASD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKQKTFHVAVVGATGAVGEQMLNTLEKREFPIGKLTLLSSKRSAGKKLVFKGEEFTVQE
CCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCEEEEEC
ATPESFEGVDIALFSAGGSVSKQLAPEAAKRGAIVVDNTSAFRMTENVPLVVPEVNENDL
CCCCCCCCEEEEEEECCCCCHHHHCHHHHHCCEEEEECCCEEEEECCCCEEEECCCCCHH
KEHNGIIANPNCSTIQMVVALEPVRQQYGLKRVIVSTYQAVSGAGAAAIEELHEQSQAIL
HHCCCEEECCCCCEEEEEEEEHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
NGEEVKANVLPVSGDKKHFPIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELEVA
CCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
ATCVRLPVVSGHSESVYIEVEKEGVTVAELKSLLANAEGIVLQDNPEEQLYPMPATAVGK
HHHHEEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEECCCCCHHEECCCCHHCCC
NEVFVGRIRKDLNNDKGFHLWVVSDNLLKGAAWNSVQIAERLVKLQLV
CCEEHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEECC
>Mature Secondary Structure
MEKQKTFHVAVVGATGAVGEQMLNTLEKREFPIGKLTLLSSKRSAGKKLVFKGEEFTVQE
CCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEECCEEEEEC
ATPESFEGVDIALFSAGGSVSKQLAPEAAKRGAIVVDNTSAFRMTENVPLVVPEVNENDL
CCCCCCCCEEEEEEECCCCCHHHHCHHHHHCCEEEEECCCEEEEECCCCEEEECCCCCHH
KEHNGIIANPNCSTIQMVVALEPVRQQYGLKRVIVSTYQAVSGAGAAAIEELHEQSQAIL
HHCCCEEECCCCCEEEEEEEEHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
NGEEVKANVLPVSGDKKHFPIAFNAIPQIDKFQDNGFTFEEMKMINETKKIMHMPELEVA
CCCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
ATCVRLPVVSGHSESVYIEVEKEGVTVAELKSLLANAEGIVLQDNPEEQLYPMPATAVGK
HHHHEEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEECCCCCHHEECCCCHHCCC
NEVFVGRIRKDLNNDKGFHLWVVSDNLLKGAAWNSVQIAERLVKLQLV
CCEEHHHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8098035; 9384377; 8345520 [H]