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The map label for this gene is yjjG [H]

Identifier: 218232695

GI number: 218232695

Start: 2640188

End: 2640880

Strand: Reverse

Name: yjjG [H]

Synonym: BCB4264_A2738

Alternate gene names: 218232695

Gene position: 2640880-2640188 (Counterclockwise)

Preceding gene: 218234254

Following gene: 218231313

Centisome position: 48.73

GC content: 29.73

Gene sequence:

>693_bases
ATGGGTTATAAAGCGATGCTGTTTGATTTAGATGATACATTACTTGATAGGGATAAAGCAGTAGAGGCATTATTTTTAAT
TGTTTTAGAAAAGTGTTATGAAAATGTAGATGGTACGGCTAAAAGCAACATGTTACAGAAATTCAAAGAATACGATAAAA
GAGAATATGGCATAAGTAATAAAACGACAGTTTTAGAATCATTGTTTGATGAATTCACGCCAAGGTATAGATTGCCACGC
AATTACATCCAAGATTTTTGGAATAATAATTTCCCTAGATGTTTTTCAATAGACAAAAATACTATTCATTTCTTAAATCA
AATAAAGAAGCACTGTAAAGTTGCAATTATAACAAATGGCTCAACTCAGAGGCAAAAAGCTAAAATATTTAACACGAATT
TAAATAGGTATTTTGAAACAATCATTATTTCTGAAGAAGTAGGATTTAGTAAACCTGATAAACGTATATTCGAACTAGCA
TTAAATAAGCTAAATTTACAACCGGAACATACTTTATTTGTTGGGGATGACTTAGAAAAGGATATTGCTGGTCCTCAAAA
TGTAAATATAAAAGGGGTGTGGTTTAACCCTCAGAAAATCAATAATACTACCAAAATACAACCATATGCCGAGATTAACA
CTTTGGATAATTTGTTAAGCTATGTTACTCCACAATATTTTTATAACAAGTAA

Upstream 100 bases:

>100_bases
CTTAGAATATCGTTCTATTACGAGTTCTTTGATATGAATTGTTTTTTTTGATTACTTTTGATGATTACTAGGAAATATAG
AAAGGTTGTGAAATGATTTG

Downstream 100 bases:

>100_bases
AAGTAATTCCGTATATATATATTAAATAATATAAAAAAAGAGAAACTATCATTAATTTCATTGACCGTATTAGTAATAAA
AAATATATACTTACTTACTC

Product: hydrolase, haloacid dehalogenase-like family

Products: NA

Alternate protein names: House-cleaning nucleotidase; Non-canonical pyrimidine nucleotide phosphatase; Nucleoside 5'-monophosphate phosphohydrolase; dUMP phosphatase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MGYKAMLFDLDDTLLDRDKAVEALFLIVLEKCYENVDGTAKSNMLQKFKEYDKREYGISNKTTVLESLFDEFTPRYRLPR
NYIQDFWNNNFPRCFSIDKNTIHFLNQIKKHCKVAIITNGSTQRQKAKIFNTNLNRYFETIIISEEVGFSKPDKRIFELA
LNKLNLQPEHTLFVGDDLEKDIAGPQNVNIKGVWFNPQKINNTTKIQPYAEINTLDNLLSYVTPQYFYNK

Sequences:

>Translated_230_residues
MGYKAMLFDLDDTLLDRDKAVEALFLIVLEKCYENVDGTAKSNMLQKFKEYDKREYGISNKTTVLESLFDEFTPRYRLPR
NYIQDFWNNNFPRCFSIDKNTIHFLNQIKKHCKVAIITNGSTQRQKAKIFNTNLNRYFETIIISEEVGFSKPDKRIFELA
LNKLNLQPEHTLFVGDDLEKDIAGPQNVNIKGVWFNPQKINNTTKIQPYAEINTLDNLLSYVTPQYFYNK
>Mature_229_residues
GYKAMLFDLDDTLLDRDKAVEALFLIVLEKCYENVDGTAKSNMLQKFKEYDKREYGISNKTTVLESLFDEFTPRYRLPRN
YIQDFWNNNFPRCFSIDKNTIHFLNQIKKHCKVAIITNGSTQRQKAKIFNTNLNRYFETIIISEEVGFSKPDKRIFELAL
NKLNLQPEHTLFVGDDLEKDIAGPQNVNIKGVWFNPQKINNTTKIQPYAEINTLDNLLSYVTPQYFYNK

Specific function: Nucleotidase that shows high phosphatase activity toward non-canonical pyrimidine nucleotides and three canonical nucleoside 5'-monophosphates (UMP, dUMP, and dTMP), and very low activity against TDP, IMP, UDP, GMP, dGMP, AMP, dAMP, and 6- phosphogluconat

COG id: COG1011

COG function: function code R; Predicted hydrolase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. YjjG family [H]

Homologues:

Organism=Homo sapiens, GI23308749, Length=116, Percent_Identity=30.1724137931034, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790833, Length=224, Percent_Identity=25.8928571428571, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI28571108, Length=238, Percent_Identity=25.6302521008403, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR011951 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 27021; Mature: 26890

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYKAMLFDLDDTLLDRDKAVEALFLIVLEKCYENVDGTAKSNMLQKFKEYDKREYGISN
CCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
KTTVLESLFDEFTPRYRLPRNYIQDFWNNNFPRCFSIDKNTIHFLNQIKKHCKVAIITNG
HHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCEEEEEECC
STQRQKAKIFNTNLNRYFETIIISEEVGFSKPDKRIFELALNKLNLQPEHTLFVGDDLEK
CCHHHHHHHHHCHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCHHH
DIAGPQNVNIKGVWFNPQKINNTTKIQPYAEINTLDNLLSYVTPQYFYNK
HCCCCCCCCEEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure 
GYKAMLFDLDDTLLDRDKAVEALFLIVLEKCYENVDGTAKSNMLQKFKEYDKREYGISN
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
KTTVLESLFDEFTPRYRLPRNYIQDFWNNNFPRCFSIDKNTIHFLNQIKKHCKVAIITNG
HHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHCEEEEEECC
STQRQKAKIFNTNLNRYFETIIISEEVGFSKPDKRIFELALNKLNLQPEHTLFVGDDLEK
CCHHHHHHHHHCHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCHHH
DIAGPQNVNIKGVWFNPQKINNTTKIQPYAEINTLDNLLSYVTPQYFYNK
HCCCCCCCCEEEEEECHHHCCCCCCCCCHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]