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The map label for this gene is insK [H]

Identifier: 218232575

GI number: 218232575

Start: 1243415

End: 1244227

Strand: Reverse

Name: insK [H]

Synonym: BCB4264_A1280

Alternate gene names: 218232575

Gene position: 1244227-1243415 (Counterclockwise)

Preceding gene: 218231776

Following gene: 218232735

Centisome position: 22.96

GC content: 34.56

Gene sequence:

>813_bases
GTGCAGGCACTTTTAAAATTAGCAGAACTCCCACGAAGTACATATTATTACTGGATACAGAATTCTAATCGGCCAGATAA
AGATAAAGAGCTAAAAATCTTAATTCAAAACATTTACGATGAACACCAAGGTCGTTATGGATATCGCCGTATTCGCGATG
AGTTAATGAACCAAGGACATAAAATCAACCATAAAAAAGTTCAACGAATTATGAAAGAGTTAGGTTTAAAGAGTCTAGTT
CGTATGAAAAAATATCGCTCGTATAAAGGACAAGTAGGTAAGATTGCGCCAAATATTTTAGAACGTAATTTTAAAGCTGA
AAAGCCGAACGAAAAATGGGTTACAGACATAACAGAATTTAAATTATGCGGCGAGAAGCTCTACTTATCACCGATGTTAG
ATCTATTTAATGGAGAGATAATCGCTTATACAATTGATTCAAGACCAACCTATTCACTTGTATCGAAGATGTTGGAGAAG
TCTTTTCAACAATTGACAGAAGAAGACGAACTCCTTATTCACTCTGATCAAGGCTGGCATTATCAAATGAAGAAGTATCG
GCACGCCCTAAAGGAACGCAAGATTACGCAAAGTATGTCTCGTAAAGGGAACTGTTACGATAATGCGGTTATTGAAAGTT
TCTTTGGTATTATGAAATCTGAATTTCTTTATCTAAAAGATTTTGAAAGCATAGAACACTTTAAACAAGAATTTGAAAAA
TATATCGATTATTATAATCACAAAAGAATTAAGGCAAAACTAAAAGGCATGAGTCCGGTACAATATCGAACTCATGCCCT
AAAGGCTGCCTAA

Upstream 100 bases:

>100_bases
ATGCTTATTTAAAAAAGTTGAATGCCTTAGTTCAAAACAAGGAAAAATCACCAAACAAGATAAGGCGCAAGTAATCTATG
AACTAAGGAAAGCATTTCCG

Downstream 100 bases:

>100_bases
TGAAACGACCTGTCTAACTTTATGGGGTCAGTTCAACCCCTCCTGTTTTTTTACATTGCTATTTTCTTTTTCTTCCGCTA
AAGTTAAATGTTGATGCTAT

Product: integrase core domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MQALLKLAELPRSTYYYWIQNSNRPDKDKELKILIQNIYDEHQGRYGYRRIRDELMNQGHKINHKKVQRIMKELGLKSLV
RMKKYRSYKGQVGKIAPNILERNFKAEKPNEKWVTDITEFKLCGEKLYLSPMLDLFNGEIIAYTIDSRPTYSLVSKMLEK
SFQQLTEEDELLIHSDQGWHYQMKKYRHALKERKITQSMSRKGNCYDNAVIESFFGIMKSEFLYLKDFESIEHFKQEFEK
YIDYYNHKRIKAKLKGMSPVQYRTHALKAA

Sequences:

>Translated_270_residues
MQALLKLAELPRSTYYYWIQNSNRPDKDKELKILIQNIYDEHQGRYGYRRIRDELMNQGHKINHKKVQRIMKELGLKSLV
RMKKYRSYKGQVGKIAPNILERNFKAEKPNEKWVTDITEFKLCGEKLYLSPMLDLFNGEIIAYTIDSRPTYSLVSKMLEK
SFQQLTEEDELLIHSDQGWHYQMKKYRHALKERKITQSMSRKGNCYDNAVIESFFGIMKSEFLYLKDFESIEHFKQEFEK
YIDYYNHKRIKAKLKGMSPVQYRTHALKAA
>Mature_270_residues
MQALLKLAELPRSTYYYWIQNSNRPDKDKELKILIQNIYDEHQGRYGYRRIRDELMNQGHKINHKKVQRIMKELGLKSLV
RMKKYRSYKGQVGKIAPNILERNFKAEKPNEKWVTDITEFKLCGEKLYLSPMLDLFNGEIIAYTIDSRPTYSLVSKMLEK
SFQQLTEEDELLIHSDQGWHYQMKKYRHALKERKITQSMSRKGNCYDNAVIESFFGIMKSEFLYLKDFESIEHFKQEFEK
YIDYYNHKRIKAKLKGMSPVQYRTHALKAA

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=252, Percent_Identity=27.7777777777778, Blast_Score=110, Evalue=1e-24,
Organism=Escherichia coli, GI1789981, Length=266, Percent_Identity=51.8796992481203, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI1788405, Length=268, Percent_Identity=30.2238805970149, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1787263, Length=268, Percent_Identity=30.2238805970149, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786753, Length=268, Percent_Identity=30.2238805970149, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786570, Length=268, Percent_Identity=30.2238805970149, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786490, Length=268, Percent_Identity=30.2238805970149, Blast_Score=141, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32391; Mature: 32391

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQALLKLAELPRSTYYYWIQNSNRPDKDKELKILIQNIYDEHQGRYGYRRIRDELMNQGH
CHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
KINHKKVQRIMKELGLKSLVRMKKYRSYKGQVGKIAPNILERNFKAEKPNEKWVTDITEF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHCCCCCCCCCCHHHHHHHHH
KLCGEKLYLSPMLDLFNGEIIAYTIDSRPTYSLVSKMLEKSFQQLTEEDELLIHSDQGWH
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCH
YQMKKYRHALKERKITQSMSRKGNCYDNAVIESFFGIMKSEFLYLKDFESIEHFKQEFEK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIDYYNHKRIKAKLKGMSPVQYRTHALKAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MQALLKLAELPRSTYYYWIQNSNRPDKDKELKILIQNIYDEHQGRYGYRRIRDELMNQGH
CHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
KINHKKVQRIMKELGLKSLVRMKKYRSYKGQVGKIAPNILERNFKAEKPNEKWVTDITEF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHCCCCCCCCCCHHHHHHHHH
KLCGEKLYLSPMLDLFNGEIIAYTIDSRPTYSLVSKMLEKSFQQLTEEDELLIHSDQGWH
HHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCH
YQMKKYRHALKERKITQSMSRKGNCYDNAVIESFFGIMKSEFLYLKDFESIEHFKQEFEK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIDYYNHKRIKAKLKGMSPVQYRTHALKAA
HHHHHHHHHHHHHHCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]