Definition Bacillus cereus B4264, complete genome.
Accession NC_011725
Length 5,419,036

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The map label for this gene is yfnA [H]

Identifier: 218232301

GI number: 218232301

Start: 227458

End: 228873

Strand: Direct

Name: yfnA [H]

Synonym: BCB4264_A0258

Alternate gene names: 218232301

Gene position: 227458-228873 (Clockwise)

Preceding gene: 218231675

Following gene: 218232957

Centisome position: 4.2

GC content: 37.99

Gene sequence:

>1416_bases
ATGAAGCAAATTTTTCAAAAGAAGCCAATTGCAAAGTTAATGCAAGAAAGTAAGCAAAAAACGTTAGCAAGAACATTGGG
CGCGCTAGATTTAACTATGCTTGGAATCGGAGCAATTGTTGGAACTGGTATTTTTGTTCTAACGGGTGTTGTGGCAGCGA
AACATTCTGGGCCAGCTATTATATTATCATTTGCGATTGCCGCTCTAGCTTGTGCCTTTGCTGCATTTTGTTATGCTGAA
TTTGCTTCTTCAGTTCCTGTCTCGGGCAGTGTGTATACGTATACATACGCGACGATGGGGGAAGTATTCGCATTTTTAAT
TGGCTGGGACTTAATGCTGGAATATTTACTTGCTACATCTGCTGTAGCGAACGGTTGGTCTGCATATTTTCAATCTTTAT
TAAAGGGGTTTGGAATTCATATTCCGACTATTCTCTCCTCGGCTCCTGGTACAGGTAAGGGTGGAATAATTGATCTACCT
GCAGTTCTAATTATTTTAGTGATGACAGTTCTTTTATCTAGGGGTGTTCGTGAAAGTGCACGAGTAAATAACATTATGGT
ATTTATTAAAATAGCAGTTGTTCTTATTTTTATCTTTGCTGGTTTTAATTATGTGAAACCTGAAAACTGGACGCCTTTTA
TGCCATTTGGTTTAGATGGTGTAATGGCTGGAGCGGCTACAGTATTCTTCGCATTTATAGGATTTGATGCAGTTTCAACA
GCGGCAGAAGAAGTGAAACGTCCGCAACGTGATTTACCAATTGGTATTATTGCATCGTTATTAATTTGTACAGTTCTTTA
TATCGTTGTTTCGCTTATTTTGACAGGAATTGTTCCATACGGACAGCTAAATATATCAGATCCAGTTGCTTTTGCACTTC
AATTTATTGGACAAGATGGTTTAGCGGGGGTAATTTCGGTAGGAGCAATTACAGGAATTACAACAGTAATGCTAGTTATG
ATGTATGGGCAAGTTCGTGTTTCTTATGCGATGAGCCGAGATGGTTTACTGCCGAAACGTCTTGCTAAAGTTCATCCGAA
ATTTAAAACGCCATTTTTAAATACATGGACAACGGGAATTATTGCGGCACTGATTTCAGGATTAATAGATTTAAATGTTT
TAGCACATCTTGTAAATATGGGGACATTGTCAGCATTTGCACTCGTAGCTGTTGCGGTAATCGTAATGAGAAGAACACAT
CCAGACTTACCAAGGGCATTTAAGGCTCCGCTTGTACCATTTTTACCAGCATTAACAGTGATCTTCTGTTTATACTTAAT
GCTTCAATTATCGGGGACAGCATGGATTAGTTTTGGGATATGGATGGTTATTGGTATAGCGGTTTACTTCTTATATAGCC
GAAAACATAGTGCTTTAAATAATAGTAAAAAAGAAGAAGATGTTGCAAATTTATAA

Upstream 100 bases:

>100_bases
ACTTGTTTCGACAAAAGTATTGACTAGGAAAAGCGTAATGAGTAAAATAAAAAAGCGAATTAAAAATTTTCAGAAAATTT
AAAACTTGGAGGAGTGAAAG

Downstream 100 bases:

>100_bases
GTGAAAAAATCCATTCTAATTCTGTTAGAATGGATTTTTTTATTTGAAAATTTACATTTTTCTGAACTTATTATAAGATA
ATTGTTGGCTAACTAAAGGG

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MKQIFQKKPIAKLMQESKQKTLARTLGALDLTMLGIGAIVGTGIFVLTGVVAAKHSGPAIILSFAIAALACAFAAFCYAE
FASSVPVSGSVYTYTYATMGEVFAFLIGWDLMLEYLLATSAVANGWSAYFQSLLKGFGIHIPTILSSAPGTGKGGIIDLP
AVLIILVMTVLLSRGVRESARVNNIMVFIKIAVVLIFIFAGFNYVKPENWTPFMPFGLDGVMAGAATVFFAFIGFDAVST
AAEEVKRPQRDLPIGIIASLLICTVLYIVVSLILTGIVPYGQLNISDPVAFALQFIGQDGLAGVISVGAITGITTVMLVM
MYGQVRVSYAMSRDGLLPKRLAKVHPKFKTPFLNTWTTGIIAALISGLIDLNVLAHLVNMGTLSAFALVAVAVIVMRRTH
PDLPRAFKAPLVPFLPALTVIFCLYLMLQLSGTAWISFGIWMVIGIAVYFLYSRKHSALNNSKKEEDVANL

Sequences:

>Translated_471_residues
MKQIFQKKPIAKLMQESKQKTLARTLGALDLTMLGIGAIVGTGIFVLTGVVAAKHSGPAIILSFAIAALACAFAAFCYAE
FASSVPVSGSVYTYTYATMGEVFAFLIGWDLMLEYLLATSAVANGWSAYFQSLLKGFGIHIPTILSSAPGTGKGGIIDLP
AVLIILVMTVLLSRGVRESARVNNIMVFIKIAVVLIFIFAGFNYVKPENWTPFMPFGLDGVMAGAATVFFAFIGFDAVST
AAEEVKRPQRDLPIGIIASLLICTVLYIVVSLILTGIVPYGQLNISDPVAFALQFIGQDGLAGVISVGAITGITTVMLVM
MYGQVRVSYAMSRDGLLPKRLAKVHPKFKTPFLNTWTTGIIAALISGLIDLNVLAHLVNMGTLSAFALVAVAVIVMRRTH
PDLPRAFKAPLVPFLPALTVIFCLYLMLQLSGTAWISFGIWMVIGIAVYFLYSRKHSALNNSKKEEDVANL
>Mature_471_residues
MKQIFQKKPIAKLMQESKQKTLARTLGALDLTMLGIGAIVGTGIFVLTGVVAAKHSGPAIILSFAIAALACAFAAFCYAE
FASSVPVSGSVYTYTYATMGEVFAFLIGWDLMLEYLLATSAVANGWSAYFQSLLKGFGIHIPTILSSAPGTGKGGIIDLP
AVLIILVMTVLLSRGVRESARVNNIMVFIKIAVVLIFIFAGFNYVKPENWTPFMPFGLDGVMAGAATVFFAFIGFDAVST
AAEEVKRPQRDLPIGIIASLLICTVLYIVVSLILTGIVPYGQLNISDPVAFALQFIGQDGLAGVISVGAITGITTVMLVM
MYGQVRVSYAMSRDGLLPKRLAKVHPKFKTPFLNTWTTGIIAALISGLIDLNVLAHLVNMGTLSAFALVAVAVIVMRRTH
PDLPRAFKAPLVPFLPALTVIFCLYLMLQLSGTAWISFGIWMVIGIAVYFLYSRKHSALNNSKKEEDVANL

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=440, Percent_Identity=39.0909090909091, Blast_Score=290, Evalue=2e-78,
Organism=Homo sapiens, GI258614005, Length=409, Percent_Identity=40.5867970660147, Blast_Score=286, Evalue=3e-77,
Organism=Homo sapiens, GI258614003, Length=409, Percent_Identity=40.5867970660147, Blast_Score=286, Evalue=4e-77,
Organism=Homo sapiens, GI258645169, Length=409, Percent_Identity=40.3422982885086, Blast_Score=279, Evalue=4e-75,
Organism=Homo sapiens, GI114326544, Length=435, Percent_Identity=36.551724137931, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI114326550, Length=435, Percent_Identity=36.551724137931, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI110347453, Length=406, Percent_Identity=38.9162561576355, Blast_Score=257, Evalue=2e-68,
Organism=Homo sapiens, GI181337167, Length=410, Percent_Identity=38.2926829268293, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI7657683, Length=404, Percent_Identity=27.7227722772277, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI186910308, Length=422, Percent_Identity=24.6445497630332, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI186910306, Length=422, Percent_Identity=24.6445497630332, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI186910304, Length=422, Percent_Identity=24.6445497630332, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI187423910, Length=462, Percent_Identity=24.8917748917749, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI7657591, Length=462, Percent_Identity=24.8917748917749, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI71979932, Length=456, Percent_Identity=25.4385964912281, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI115648063, Length=432, Percent_Identity=24.0740740740741, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI115648022, Length=432, Percent_Identity=24.0740740740741, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI33286428, Length=451, Percent_Identity=24.6119733924612, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI71999149, Length=411, Percent_Identity=25.0608272506083, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI87082023, Length=472, Percent_Identity=26.271186440678, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081869, Length=469, Percent_Identity=26.226012793177, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1788480, Length=449, Percent_Identity=25.3897550111359, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87081708, Length=492, Percent_Identity=22.3577235772358, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87082250, Length=351, Percent_Identity=28.2051282051282, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1786694, Length=420, Percent_Identity=24.7619047619048, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1786302, Length=476, Percent_Identity=24.7899159663866, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789017, Length=354, Percent_Identity=22.316384180791, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786602, Length=415, Percent_Identity=23.3734939759036, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786908, Length=427, Percent_Identity=23.4192037470726, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786789, Length=431, Percent_Identity=22.2737819025522, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367353, Length=377, Percent_Identity=24.6684350132626, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI87081915, Length=425, Percent_Identity=21.6470588235294, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790653, Length=442, Percent_Identity=19.4570135746606, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI48994972, Length=347, Percent_Identity=22.7665706051873, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=388, Percent_Identity=37.8865979381443, Blast_Score=258, Evalue=5e-69,
Organism=Caenorhabditis elegans, GI17531343, Length=391, Percent_Identity=38.8746803069054, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17533459, Length=406, Percent_Identity=35.4679802955665, Blast_Score=235, Evalue=4e-62,
Organism=Caenorhabditis elegans, GI17540018, Length=433, Percent_Identity=26.3279445727483, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982612, Length=434, Percent_Identity=22.3502304147465, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71982608, Length=434, Percent_Identity=22.3502304147465, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17568033, Length=423, Percent_Identity=27.1867612293144, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI32566695, Length=436, Percent_Identity=24.7706422018349, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193208714, Length=428, Percent_Identity=24.5327102803738, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17537453, Length=376, Percent_Identity=23.4042553191489, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=355, Percent_Identity=25.6338028169014, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71993915, Length=389, Percent_Identity=22.107969151671, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321751, Length=429, Percent_Identity=22.6107226107226, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI221512776, Length=415, Percent_Identity=37.3493975903614, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24666159, Length=415, Percent_Identity=37.3493975903614, Blast_Score=291, Evalue=6e-79,
Organism=Drosophila melanogaster, GI24667468, Length=416, Percent_Identity=38.7019230769231, Blast_Score=283, Evalue=2e-76,
Organism=Drosophila melanogaster, GI24668806, Length=412, Percent_Identity=37.8640776699029, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI21356285, Length=412, Percent_Identity=37.8640776699029, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI24668802, Length=412, Percent_Identity=37.8640776699029, Blast_Score=279, Evalue=3e-75,
Organism=Drosophila melanogaster, GI161077963, Length=424, Percent_Identity=36.7924528301887, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI281366235, Length=411, Percent_Identity=36.2530413625304, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI116007820, Length=411, Percent_Identity=36.2530413625304, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI116007818, Length=397, Percent_Identity=36.272040302267, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI85725152, Length=397, Percent_Identity=36.272040302267, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI21357367, Length=429, Percent_Identity=25.4079254079254, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI221331183, Length=474, Percent_Identity=25.7383966244726, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17647653, Length=474, Percent_Identity=25.7383966244726, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24664379, Length=474, Percent_Identity=25.7383966244726, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24651635, Length=407, Percent_Identity=25.5528255528256, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24651633, Length=407, Percent_Identity=25.5528255528256, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45550968, Length=477, Percent_Identity=23.4800838574423, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19921172, Length=477, Percent_Identity=23.4800838574423, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24641993, Length=421, Percent_Identity=25.1781472684086, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24641995, Length=421, Percent_Identity=25.1781472684086, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50566; Mature: 50566

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure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HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]