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The map label for this gene is yfjP [H]

Identifier: 218232083

GI number: 218232083

Start: 476236

End: 477099

Strand: Direct

Name: yfjP [H]

Synonym: BCB4264_A0490

Alternate gene names: 218232083

Gene position: 476236-477099 (Clockwise)

Preceding gene: 218231287

Following gene: 218231359

Centisome position: 8.79

GC content: 36.0

Gene sequence:

>864_bases
ATGTGGAGCGAGCATGTTACGTTAGAGTATCCGTATCATTTTGAAGAAGTATTAAAACGTTTAGCTTTTGATCCTCTTAA
CGTCATTCAATTAGATGAGAAAGTTATTTATATCCCGCTTTGTATAGACGAGGAACAGGTTGTTGTTCGCTTACAAGGGA
TTGGTACTGTTCAAAATCCACAGTTTTGGATTTCTAGTCAGACAGGAGATCCAGAGAAAGTCATGAAACGAATGAGGGCC
ATTTTTCATTGGAATGAACCGTTTCAAGATATACAAAATCATTTTTTAAACACATCATTACGTCCACTATTTGAAACATA
TGCTTATACTCCAATTATTTTAGAATTTGATTATTTTGCTTGTCTGCTTCGCTGTATCATTCACCAACAAATAAATTTGA
AATTTGCTACTGTGTTAACAGAACAATTTGTGAAACGGTATGGAACAGAGAAGAACGGTGTATTCTTTTTCCCCACTCCG
GAAATAGTAGCAAATATTTCAATAGAAGAATTGAGAGAGCAGAAGTTTAGTCAGCGAAAGGCTGAATATATAGTAGGATT
AGGTCGAAGTATTGTCAGTGGTACATTAAATTTAGCGAGTATAGAAAATGGGACGGAAGAAGACATTTCAGCACAATTGT
TGCCAATTAGGGGAATTGGTGCATGGACAGTGCAAAACTTTTTAATGTTTGGGCTTGGACGGAAAAATATGTTCCCGAAA
GCGGACATTGGGATTCAGCGTGCAGTGCAAGGTATATTTCAATTAGATGATAAACCTGATGATGCATTTTTAGAAAAAGT
GAAACAAGAGTGTGAACCATACTGCAGTTATGCAGCGTTATATTTATGGAAAAGTATAGAGTAG

Upstream 100 bases:

>100_bases
TTAAAAGTCTAGATGACTTAGTAAAAGGCAATCAACCGTAAGCATGTATGCTTACGGTTTTCTCATGCTATAATGATGTG
TAAAAAGGATGGGGAAACGT

Downstream 100 bases:

>100_bases
AGGTGTAATAATGATACAAAAGCAACATGAGAGTAAGTTGGAAGTTGGTCAAACGTTTCCTGTGACAATTAAACGTCTTG
GGATTAACGGAGAAGGCGTT

Product: endonuclease III domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MWSEHVTLEYPYHFEEVLKRLAFDPLNVIQLDEKVIYIPLCIDEEQVVVRLQGIGTVQNPQFWISSQTGDPEKVMKRMRA
IFHWNEPFQDIQNHFLNTSLRPLFETYAYTPIILEFDYFACLLRCIIHQQINLKFATVLTEQFVKRYGTEKNGVFFFPTP
EIVANISIEELREQKFSQRKAEYIVGLGRSIVSGTLNLASIENGTEEDISAQLLPIRGIGAWTVQNFLMFGLGRKNMFPK
ADIGIQRAVQGIFQLDDKPDDAFLEKVKQECEPYCSYAALYLWKSIE

Sequences:

>Translated_287_residues
MWSEHVTLEYPYHFEEVLKRLAFDPLNVIQLDEKVIYIPLCIDEEQVVVRLQGIGTVQNPQFWISSQTGDPEKVMKRMRA
IFHWNEPFQDIQNHFLNTSLRPLFETYAYTPIILEFDYFACLLRCIIHQQINLKFATVLTEQFVKRYGTEKNGVFFFPTP
EIVANISIEELREQKFSQRKAEYIVGLGRSIVSGTLNLASIENGTEEDISAQLLPIRGIGAWTVQNFLMFGLGRKNMFPK
ADIGIQRAVQGIFQLDDKPDDAFLEKVKQECEPYCSYAALYLWKSIE
>Mature_287_residues
MWSEHVTLEYPYHFEEVLKRLAFDPLNVIQLDEKVIYIPLCIDEEQVVVRLQGIGTVQNPQFWISSQTGDPEKVMKRMRA
IFHWNEPFQDIQNHFLNTSLRPLFETYAYTPIILEFDYFACLLRCIIHQQINLKFATVLTEQFVKRYGTEKNGVFFFPTP
EIVANISIEELREQKFSQRKAEYIVGLGRSIVSGTLNLASIENGTEEDISAQLLPIRGIGAWTVQNFLMFGLGRKNMFPK
ADIGIQRAVQGIFQLDDKPDDAFLEKVKQECEPYCSYAALYLWKSIE

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 33334; Mature: 33334

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSEHVTLEYPYHFEEVLKRLAFDPLNVIQLDEKVIYIPLCIDEEQVVVRLQGIGTVQNP
CCCCCEEEECCCCHHHHHHHHCCCCCCEEEECCEEEEEEEEECCCEEEEEEECCCCCCCC
QFWISSQTGDPEKVMKRMRAIFHWNEPFQDIQNHFLNTSLRPLFETYAYTPIILEFDYFA
CEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEHHHHH
CLLRCIIHQQINLKFATVLTEQFVKRYGTEKNGVFFFPTPEIVANISIEELREQKFSQRK
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHH
AEYIVGLGRSIVSGTLNLASIENGTEEDISAQLLPIRGIGAWTVQNFLMFGLGRKNMFPK
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCC
ADIGIQRAVQGIFQLDDKPDDAFLEKVKQECEPYCSYAALYLWKSIE
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MWSEHVTLEYPYHFEEVLKRLAFDPLNVIQLDEKVIYIPLCIDEEQVVVRLQGIGTVQNP
CCCCCEEEECCCCHHHHHHHHCCCCCCEEEECCEEEEEEEEECCCEEEEEEECCCCCCCC
QFWISSQTGDPEKVMKRMRAIFHWNEPFQDIQNHFLNTSLRPLFETYAYTPIILEFDYFA
CEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEHHHHH
CLLRCIIHQQINLKFATVLTEQFVKRYGTEKNGVFFFPTPEIVANISIEELREQKFSQRK
HHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHCCCHHHHHHHHHHHHH
AEYIVGLGRSIVSGTLNLASIENGTEEDISAQLLPIRGIGAWTVQNFLMFGLGRKNMFPK
HHHHHHHHHHHHHCCCEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCC
ADIGIQRAVQGIFQLDDKPDDAFLEKVKQECEPYCSYAALYLWKSIE
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]