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The map label for this gene is fruR [H]

Identifier: 218231971

GI number: 218231971

Start: 3729722

End: 3730474

Strand: Reverse

Name: fruR [H]

Synonym: BCB4264_A3818

Alternate gene names: 218231971

Gene position: 3730474-3729722 (Counterclockwise)

Preceding gene: 218231360

Following gene: 218231935

Centisome position: 68.84

GC content: 33.47

Gene sequence:

>753_bases
ATGTTAACTCCTGAACGTCATCAAATGATATTGCAACTTGTAAAAGAACAGAAAGTTGTAAAATTACAGCAATTAGTTGA
AAGAACAGAAAGCTCTGAATCGACAATTCGCCGTGATTTAGCGCAATTGGAAAAGCAAAGGTTATTAAAAAGAGTTCATG
GTGGTGCCGCTGTTTTAACAGGAAAAGGGCAAGAACCAACGATGGTTGAAAAATCATCCAAAAACATTCAAATAAAACAA
CAAATTGCTAAGTATGCGGCTAGCGTTATTGAACAAGGTGATTGTATTTATTTAGATGCAGGAAGTACAACATTTGAAAT
GATTCCATTTTTAATAAATAAAGATGTTACTGTCGTTACGAATGGACTTATGCATATTGAAGCTTTAGTTGAAAATAATA
TTCGTGCGTATTTACTAGGCGGAATGATGAAGAGTAGGACGAAAGCTTTAATCGGTGCTATGGCACAGGAAAGTATGCAG
AAGTATCGTTTTGATAAATGTTTTTTAGGTGCAAATGGTGTACATGAACAGCTTGGCTTTACAACGCCAGATCCAGAAGA
AGCGCTCTTAAAACAAATGGCATTAACATTAGCAAACGAAGGATATTTCTTAATTGATGAAAGTAAGTTTTCAGAAGTTG
CATTTGCGAAAATTGCAAATGTTGAAGATGCAAATATTATTACAAACCATTTAGAAATTGATTTAGAAAAATATAAACAA
CAAACCAATGTAATTGAGGCTGATAAACAATGA

Upstream 100 bases:

>100_bases
TTTATAAACGTTTTTGGATGTTTTTGATTATTTTTGATTGTTTACGGTTGATTTTTGTGACCGTTTTCATTATACTGTAA
TCAAAGAAGAGGTGAATAAA

Downstream 100 bases:

>100_bases
TCTATACAGTTACTTTAAACCCATCTATTGATTATGTAGTGCAAGTTTCTTCTTTTGATTTAGGAACAATAAATCGAGCG
GAAAAAGATATGAAGTTTCC

Product: transcriptional regulator, DeoR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MLTPERHQMILQLVKEQKVVKLQQLVERTESSESTIRRDLAQLEKQRLLKRVHGGAAVLTGKGQEPTMVEKSSKNIQIKQ
QIAKYAASVIEQGDCIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEDANIITNHLEIDLEKYKQ
QTNVIEADKQ

Sequences:

>Translated_250_residues
MLTPERHQMILQLVKEQKVVKLQQLVERTESSESTIRRDLAQLEKQRLLKRVHGGAAVLTGKGQEPTMVEKSSKNIQIKQ
QIAKYAASVIEQGDCIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEDANIITNHLEIDLEKYKQ
QTNVIEADKQ
>Mature_250_residues
MLTPERHQMILQLVKEQKVVKLQQLVERTESSESTIRRDLAQLEKQRLLKRVHGGAAVLTGKGQEPTMVEKSSKNIQIKQ
QIAKYAASVIEQGDCIYLDAGSTTFEMIPFLINKDVTVVTNGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQ
KYRFDKCFLGANGVHEQLGFTTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEDANIITNHLEIDLEKYKQ
QTNVIEADKQ

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=230, Percent_Identity=33.9130434782609, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI226510968, Length=216, Percent_Identity=31.4814814814815, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789059, Length=233, Percent_Identity=30.9012875536481, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787540, Length=227, Percent_Identity=32.15859030837, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1789829, Length=219, Percent_Identity=30.5936073059361, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788069, Length=229, Percent_Identity=29.6943231441048, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1787063, Length=245, Percent_Identity=27.7551020408163, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082344, Length=223, Percent_Identity=24.6636771300448, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790753, Length=214, Percent_Identity=24.2990654205607, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790635, Length=215, Percent_Identity=25.5813953488372, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=26.0683760683761, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28103; Mature: 28103

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTPERHQMILQLVKEQKVVKLQQLVERTESSESTIRRDLAQLEKQRLLKRVHGGAAVLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GKGQEPTMVEKSSKNIQIKQQIAKYAASVIEQGDCIYLDAGSTTFEMIPFLINKDVTVVT
CCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCHHHHH
NGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQKYRFDKCFLGANGVHEQLGF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
TTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEDANIITNHLEIDLEKYKQ
CCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
QTNVIEADKQ
HHCCCCCCCC
>Mature Secondary Structure
MLTPERHQMILQLVKEQKVVKLQQLVERTESSESTIRRDLAQLEKQRLLKRVHGGAAVLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GKGQEPTMVEKSSKNIQIKQQIAKYAASVIEQGDCIYLDAGSTTFEMIPFLINKDVTVVT
CCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCHHHHH
NGLMHIEALVENNIRAYLLGGMMKSRTKALIGAMAQESMQKYRFDKCFLGANGVHEQLGF
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
TTPDPEEALLKQMALTLANEGYFLIDESKFSEVAFAKIANVEDANIITNHLEIDLEKYKQ
CCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
QTNVIEADKQ
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]