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The map label for this gene is coaD [H]

Identifier: 218231719

GI number: 218231719

Start: 3954103

End: 3954594

Strand: Reverse

Name: coaD [H]

Synonym: BCB4264_A4030

Alternate gene names: 218231719

Gene position: 3954594-3954103 (Counterclockwise)

Preceding gene: 218232815

Following gene: 218230835

Centisome position: 72.98

GC content: 33.33

Gene sequence:

>492_bases
ATGACAAGTATAGCTATTTCTTCAGGAAGTTTTGATCCAATTACCCTTGGGCATCTGGATATTATTAAAAGGGGAGCAAA
AGTATTTGATGAGGTGTACGTAGTCGTTTTAAACAATTCATCAAAAAAACCATTCTTTTCAGTTGAAGAGCGATTAGAAT
TAATTCGAGAAGCGACAAAGGATATCCCGAATGTAAAAGTAGATTCGCATAGTGGGCTATTAGTAGAGTATGCAAAAATG
CGTAATGCAAATGCAATATTACGTGGTTTACGAGCAGTTTCTGATTTTGAATATGAGATGCAAATTACTTCTATGAATCG
AAAATTAGATGAAAATATTGAAACATTTTTTATTATGACAAACAATCAATATTCATTTTTAAGCTCGAGTATTGTAAAAG
AAGTTGCGAGGTATGGAGGAAGTGTAGTAGATCTTGTACCCCCTATTGTAGAACGTGCTTTAAAAGAAAAGTTTCAAACC
CCGTTAAAGTGA

Upstream 100 bases:

>100_bases
TAGTTTTACCTAATTCAATAGGAAGGCTTGTAAAAGTACGAGCTGAGAATTATGGGATTACTGCAATATCGATTTATAAG
TATGAAGGTGAGGGGACAGA

Downstream 100 bases:

>100_bases
ACGGGGTTTTTCTTTATATGTGCGCAAAAATAATAAAATAACATATAAGTATAGACAAAATAATGTGAAAATTGGTCCAT
AATGTATAAAAGATGTCCAA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT [H]

Number of amino acids: Translated: 163; Mature: 162

Protein sequence:

>163_residues
MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLELIREATKDIPNVKVDSHSGLLVEYAKM
RNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPIVERALKEKFQT
PLK

Sequences:

>Translated_163_residues
MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLELIREATKDIPNVKVDSHSGLLVEYAKM
RNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPIVERALKEKFQT
PLK
>Mature_162_residues
TSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLELIREATKDIPNVKVDSHSGLLVEYAKMR
NANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMTNNQYSFLSSSIVKEVARYGGSVVDLVPPIVERALKEKFQTP
LK

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate [H]

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family [H]

Homologues:

Organism=Escherichia coli, GI1790065, Length=158, Percent_Identity=46.2025316455696, Blast_Score=156, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.3 [H]

Molecular weight: Translated: 18407; Mature: 18276

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLELIREATK
CCEEECCCCCCCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHH
DIPNVKVDSHSGLLVEYAKMRNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMT
CCCCCEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCHHEEEEHHHHHHHHCCCEEEEEEE
NNQYSFLSSSIVKEVARYGGSVVDLVPPIVERALKEKFQTPLK
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSIAISSGSFDPITLGHLDIIKRGAKVFDEVYVVVLNNSSKKPFFSVEERLELIREATK
CEEECCCCCCCCEEHHHHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHHHHH
DIPNVKVDSHSGLLVEYAKMRNANAILRGLRAVSDFEYEMQITSMNRKLDENIETFFIMT
CCCCCEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCHHEEEEHHHHHHHHCCCEEEEEEE
NNQYSFLSSSIVKEVARYGGSVVDLVPPIVERALKEKFQTPLK
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA