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The map label for this gene is aspB [H]

Identifier: 218231550

GI number: 218231550

Start: 1526720

End: 1527907

Strand: Direct

Name: aspB [H]

Synonym: BCB4264_A1601

Alternate gene names: 218231550

Gene position: 1526720-1527907 (Clockwise)

Preceding gene: 218230833

Following gene: 218232332

Centisome position: 28.17

GC content: 37.54

Gene sequence:

>1188_bases
ATGAAATTAGCAAAGCGAGTAGCTGCTTTAACACCGTCTTCAACTTTAGAAATTACAGCAAAGGCACAAGCATTAAAAGC
AGAGGGTCATGATGTAATTGCATTAGGGGCAGGGGAACCTGACTTTAATACACCAGAGCATATTATGGATGCTGCACATA
AAGCGATGTTAGAAGGGCATACGAAGTATACACCAACAGGTGGATTACAATCGTTAAAACAAGAAATTGTGAAGAAATTT
ACTCGCGATCAAGGTATTGCGTATGATCCATCTGAAATTATTGTATGTAATGGTGCAAAGCATGCATTGTATACATTATT
CCAAGTATTACTTGATGAGGGAGATGAAGTTATCATCCCAACTCCTTACTGGGTAAGCTATCCAGAGCAAGTAAAGCTTG
CTGGCGGTAAGCCGGTTTATGTAGAAGGTTTAGAAGACAATGAGTACAAAATTACAGCAAAGCAGCTGCGTGAGGCAATT
ACAGAGAAAACGAAAGCAGTTATTATTAATTCACCGAGCAATCCAACAGGAATGATTTATAGCAAAGAAGAATTACAACA
GCTTGGAGAAGTATGTTTAGAACATGATATTTTAATCGTTTCTGATGAAATTTATGAAAAATTAATTTATGGTGGCGTAG
AATATACTTCAATTGCCCAGCTTTCTAATGCATTAAAAGAACAAACACTTATTATTAATGGTGTATCTAAATCTCATTCT
ATGACAGGATGGCGTATTGGATATGCTGCAGGAAATAAGCAGCTTATTAAAGCGATGACGAACTTAGCGAGTCATAGTAC
GTCAAACCCTACTTCAATCGCTCAATACGGCGCAATTGCGGCATATGCAGGCTCACAAGAACCTGTGGAAACAATGCGTC
AAGCCTTTGAAGAGAGATTAAACATCATTTATGATAAATTAATTCAAATCCCTGGCTTTACTTGCATTAAACCGCAAGGT
GCATTTTACTTATTCCCTAACGTAAAAGAAGCTGTAGCTTTATCAGGATATGCAACAGTTGATGATTGGGCAAAAGCTCT
ATTAGAAGAGGAAAAAGTGGCTCTTGTACCAGGTACAGGATTTGGTGCTCCAAATAATGTTCGCTTATCATATGCGACAT
CTCTTGAACAAGTAGAGAAAGCATTAGAGCGTATCCATACATTTATGAAAAGTAAAGTGCAAGCTTAA

Upstream 100 bases:

>100_bases
TGATGATGACAATCGTTATAGTTATTACTATCTTGAATTTAAAGATGGAAAATTTTTAAGACGATATAGCATTGAAAAAT
AGATGTAGGGGGAACTACAA

Downstream 100 bases:

>100_bases
TTTTATATTTCATTCATGTAATATAAAAAACCTCCCCATTAATAGGGAGGTTTTTTTGACGAATTGTGGCAAAAAGAAAT
AGCTAAAGGTGTGTTATACT

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MKLAKRVAALTPSSTLEITAKAQALKAEGHDVIALGAGEPDFNTPEHIMDAAHKAMLEGHTKYTPTGGLQSLKQEIVKKF
TRDQGIAYDPSEIIVCNGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGKPVYVEGLEDNEYKITAKQLREAI
TEKTKAVIINSPSNPTGMIYSKEELQQLGEVCLEHDILIVSDEIYEKLIYGGVEYTSIAQLSNALKEQTLIINGVSKSHS
MTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGSQEPVETMRQAFEERLNIIYDKLIQIPGFTCIKPQG
AFYLFPNVKEAVALSGYATVDDWAKALLEEEKVALVPGTGFGAPNNVRLSYATSLEQVEKALERIHTFMKSKVQA

Sequences:

>Translated_395_residues
MKLAKRVAALTPSSTLEITAKAQALKAEGHDVIALGAGEPDFNTPEHIMDAAHKAMLEGHTKYTPTGGLQSLKQEIVKKF
TRDQGIAYDPSEIIVCNGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGKPVYVEGLEDNEYKITAKQLREAI
TEKTKAVIINSPSNPTGMIYSKEELQQLGEVCLEHDILIVSDEIYEKLIYGGVEYTSIAQLSNALKEQTLIINGVSKSHS
MTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGSQEPVETMRQAFEERLNIIYDKLIQIPGFTCIKPQG
AFYLFPNVKEAVALSGYATVDDWAKALLEEEKVALVPGTGFGAPNNVRLSYATSLEQVEKALERIHTFMKSKVQA
>Mature_395_residues
MKLAKRVAALTPSSTLEITAKAQALKAEGHDVIALGAGEPDFNTPEHIMDAAHKAMLEGHTKYTPTGGLQSLKQEIVKKF
TRDQGIAYDPSEIIVCNGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGKPVYVEGLEDNEYKITAKQLREAI
TEKTKAVIINSPSNPTGMIYSKEELQQLGEVCLEHDILIVSDEIYEKLIYGGVEYTSIAQLSNALKEQTLIINGVSKSHS
MTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGSQEPVETMRQAFEERLNIIYDKLIQIPGFTCIKPQG
AFYLFPNVKEAVALSGYATVDDWAKALLEEEKVALVPGTGFGAPNNVRLSYATSLEQVEKALERIHTFMKSKVQA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=324, Percent_Identity=30.8641975308642, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI169881279, Length=324, Percent_Identity=30.8641975308642, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI56713254, Length=342, Percent_Identity=28.9473684210526, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI56713256, Length=342, Percent_Identity=28.9473684210526, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI4507369, Length=375, Percent_Identity=25.6, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI169881281, Length=321, Percent_Identity=25.2336448598131, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI215599424, Length=377, Percent_Identity=23.6074270557029, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI19263340, Length=377, Percent_Identity=23.6074270557029, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI4885351, Length=387, Percent_Identity=25.0645994832041, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI187936925, Length=203, Percent_Identity=29.5566502463054, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI14211921, Length=203, Percent_Identity=29.5566502463054, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI149944424, Length=200, Percent_Identity=26.5, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1788627, Length=391, Percent_Identity=29.6675191815857, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788722, Length=391, Percent_Identity=29.4117647058824, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786816, Length=368, Percent_Identity=26.0869565217391, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1787909, Length=368, Percent_Identity=23.9130434782609, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=416, Percent_Identity=29.8076923076923, Blast_Score=154, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71994476, Length=416, Percent_Identity=29.8076923076923, Blast_Score=154, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI17567369, Length=396, Percent_Identity=28.030303030303, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17567663, Length=375, Percent_Identity=25.8666666666667, Blast_Score=138, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6322401, Length=398, Percent_Identity=30.6532663316583, Blast_Score=160, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6320317, Length=339, Percent_Identity=26.2536873156342, Blast_Score=97, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6323118, Length=343, Percent_Identity=28.8629737609329, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573069, Length=292, Percent_Identity=30.8219178082192, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24646114, Length=292, Percent_Identity=30.8219178082192, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28573067, Length=292, Percent_Identity=30.8219178082192, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28573065, Length=292, Percent_Identity=30.8219178082192, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=24.468085106383, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI45551451, Length=395, Percent_Identity=23.2911392405063, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641770, Length=395, Percent_Identity=23.2911392405063, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641760, Length=395, Percent_Identity=23.2911392405063, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641768, Length=395, Percent_Identity=23.2911392405063, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641766, Length=395, Percent_Identity=23.2911392405063, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641764, Length=395, Percent_Identity=23.2911392405063, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43255; Mature: 43255

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAKRVAALTPSSTLEITAKAQALKAEGHDVIALGAGEPDFNTPEHIMDAAHKAMLEGH
CCHHHHHHHCCCCCCEEEEEHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCC
TKYTPTGGLQSLKQEIVKKFTRDQGIAYDPSEIIVCNGAKHALYTLFQVLLDEGDEVIIP
CCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCCHHHHHHHHHHHHCCCCCEEEC
TPYWVSYPEQVKLAGGKPVYVEGLEDNEYKITAKQLREAITEKTKAVIINSPSNPTGMIY
CCCCCCCCCCEEECCCCEEEEECCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCCCEEE
SKEELQQLGEVCLEHDILIVSDEIYEKLIYGGVEYTSIAQLSNALKEQTLIINGVSKSHS
CHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCCCCC
MTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGSQEPVETMRQAFEERL
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCEEECCCCCHHHHHHHHHHHHH
NIIYDKLIQIPGFTCIKPQGAFYLFPNVKEAVALSGYATVDDWAKALLEEEKVALVPGTG
HHHHHHHHHCCCCEEECCCCCEEECCCCHHHHHCCCCCCHHHHHHHHHCCCCEEEECCCC
FGAPNNVRLSYATSLEQVEKALERIHTFMKSKVQA
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKLAKRVAALTPSSTLEITAKAQALKAEGHDVIALGAGEPDFNTPEHIMDAAHKAMLEGH
CCHHHHHHHCCCCCCEEEEEHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCC
TKYTPTGGLQSLKQEIVKKFTRDQGIAYDPSEIIVCNGAKHALYTLFQVLLDEGDEVIIP
CCCCCCHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCCHHHHHHHHHHHHCCCCCEEEC
TPYWVSYPEQVKLAGGKPVYVEGLEDNEYKITAKQLREAITEKTKAVIINSPSNPTGMIY
CCCCCCCCCCEEECCCCEEEEECCCCCCEEEEHHHHHHHHHHCCCEEEEECCCCCCCEEE
SKEELQQLGEVCLEHDILIVSDEIYEKLIYGGVEYTSIAQLSNALKEQTLIINGVSKSHS
CHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHCEEEEECCCCCCC
MTGWRIGYAAGNKQLIKAMTNLASHSTSNPTSIAQYGAIAAYAGSQEPVETMRQAFEERL
CCCEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCEEECCCCCHHHHHHHHHHHHH
NIIYDKLIQIPGFTCIKPQGAFYLFPNVKEAVALSGYATVDDWAKALLEEEKVALVPGTG
HHHHHHHHHCCCCEEECCCCCEEECCCCHHHHHCCCCCCHHHHHHHHHCCCCEEEECCCC
FGAPNNVRLSYATSLEQVEKALERIHTFMKSKVQA
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]