Click here to switch to the map view.

The map label for this gene is pyrH [H]

Identifier: 218231216

GI number: 218231216

Start: 1712771

End: 1713514

Strand: Reverse

Name: pyrH [H]

Synonym: BCB4264_A1808

Alternate gene names: 218231216

Gene position: 1713514-1712771 (Counterclockwise)

Preceding gene: 218231968

Following gene: 218235233

Centisome position: 31.62

GC content: 39.52

Gene sequence:

>744_bases
ATGAGACCATATAAACGTGTCTTAATTAAATTAAGCGGCGGTGCACTTGCCGATCAAACTGGAAATAGCTTTAACTCCAA
ACGATTAGAACATATCGCAAACGAAATTTTATCCATTGTTGATTTAGGTATCGAAGTATCCATCGTCATCGGTGGCGGTA
ACATTTTTAGGGGACATCTAGCTGAAGAATGGGGAATCGATCGCGTAGAAGCTGATAATATCGGTACGTTAGGTACAATC
ATTAACAGCTTAATGCTTCGCGGTGTTTTAACAAGTAAAACAAATAGAGAAGTACGCGTTATGACGTCCATTCCATTTAA
TGCAGTAGCTGAACCATACATTCGCTTGCGTGCAGTCCACCATTTAGATAACGGTTATATCGTTATCTTTGGAGGCGGAA
ACGGGCAACCGTTCGTGACGACAGATTATCCAAGTGTACAAAGAGCCATTGAAATGAATAGTGATGCCATATTAGTCGCA
AAACAGGGTGTCGATGGCGTTTTTACAAGTGATCCGAAGCATAACAAATCAGCAAAAATGTACAGCAAACTAAACTATAA
TGATGTCGTTAGACAAAATATACAAGTTATGGATCAAGCGGCATTACTGCTTGCCCGGGACTACAATTTACCAGCACATG
TCTTTAACTTTGATGAGCCTGGAGTCATGAAAAAAATATGTTTAGGCGAACATGTGGGGACATTGATTAATGATGATGTT
ACGATGTTGGTGCATGAAAAATAA

Upstream 100 bases:

>100_bases
TTCGTCCTATCTTCTTCTTTTCTTTTTCATTTTCTTAAAAAGGAACAAAGGCATTCGCCTTTGTTCCTTTTTTATTGCGA
TCTATATAGGGGGAATTGTT

Downstream 100 bases:

>100_bases
TGATTTCCCACCAAAAAAGGGTGTCTTTTGTAGGCACCCTTTCCTAATTCATCATCACAAATAGAAGTCAACCAATCCCG
CCACTTTCTCCTTACAACGC

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHLAEEWGIDRVEADNIGTLGTI
INSLMLRGVLTSKTNREVRVMTSIPFNAVAEPYIRLRAVHHLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVA
KQGVDGVFTSDPKHNKSAKMYSKLNYNDVVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMKKICLGEHVGTLINDDV
TMLVHEK

Sequences:

>Translated_247_residues
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHLAEEWGIDRVEADNIGTLGTI
INSLMLRGVLTSKTNREVRVMTSIPFNAVAEPYIRLRAVHHLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVA
KQGVDGVFTSDPKHNKSAKMYSKLNYNDVVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMKKICLGEHVGTLINDDV
TMLVHEK
>Mature_247_residues
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHLAEEWGIDRVEADNIGTLGTI
INSLMLRGVLTSKTNREVRVMTSIPFNAVAEPYIRLRAVHHLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVA
KQGVDGVFTSDPKHNKSAKMYSKLNYNDVVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMKKICLGEHVGTLINDDV
TMLVHEK

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=235, Percent_Identity=42.9787234042553, Blast_Score=204, Evalue=4e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 27228; Mature: 27228

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHL
CCCHHEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCC
AEEWGIDRVEADNIGTLGTIINSLMLRGVLTSKTNREVRVMTSIPFNAVAEPYIRLRAVH
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHE
HLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVAKQGVDGVFTSDPKHNKSAKM
ECCCCEEEEEECCCCCCEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHH
YSKLNYNDVVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMKKICLGEHVGTLINDDV
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCE
TMLVHEK
EEEEECC
>Mature Secondary Structure
MRPYKRVLIKLSGGALADQTGNSFNSKRLEHIANEILSIVDLGIEVSIVIGGGNIFRGHL
CCCHHEEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCEEECCC
AEEWGIDRVEADNIGTLGTIINSLMLRGVLTSKTNREVRVMTSIPFNAVAEPYIRLRAVH
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHE
HLDNGYIVIFGGGNGQPFVTTDYPSVQRAIEMNSDAILVAKQGVDGVFTSDPKHNKSAKM
ECCCCEEEEEECCCCCCEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCHHH
YSKLNYNDVVRQNIQVMDQAALLLARDYNLPAHVFNFDEPGVMKKICLGEHVGTLINDDV
HHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCE
TMLVHEK
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA