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The map label for this gene is maeN [H]

Identifier: 218231115

GI number: 218231115

Start: 596572

End: 597918

Strand: Direct

Name: maeN [H]

Synonym: BCB4264_A0616

Alternate gene names: 218231115

Gene position: 596572-597918 (Clockwise)

Preceding gene: 218231939

Following gene: 218235748

Centisome position: 11.01

GC content: 36.01

Gene sequence:

>1347_bases
ATGGGAATTCAAAAGAATGTGGAAGCGGTATCATTTTCTGAAGGAAATGAAGTACAAAGAGAATCTTTCGCTTCTAAAAT
TATGAATGTAAAAATCGGTGTTATACCTTTACCGTTATATGTAGTATTGGCTGCTATTATTTATGGGGCATCTGTATATA
ATAAATTGCCAGCAGATATGATTGGTGGATTTGCAGTTATTATGATCATGGGGATTTTCTTAGGCGATATTGGGATGAGA
ATTCCAATTTTAAAAAATATCGGCGGTCCAGCAATACTTTCGTTATTTATTCCATCATTACTTGTATTTTTTAACTGGAT
GAATCCAGCTTCAATGGAAGCTGCGACTATGTTAATGAAAAAATCGAACTTTTTATATTTATATATTTCTTGTTTAGTAG
TCGGAAGTATTTTAGGAATGAACCGTAAAGTGTTAGTACAAGGTTTCGTTCGCATGTTTATTCCTTTAGTAGTAGGGACG
TTAGCTTCTGTAGCAGTAGGGTTATTGGTCGGTTCATTATTTGGATTTGAAATGAAGCACACATTCTTCTTTATCATCGT
ACCAATTGTAAGTGGTGGTATCGGGGAAGGGATTTTACCATTGTCGCTAGCTTATAGTGATATTTTAAATGAATCGTCAG
CAACGTTTGTATCACAGCTTATTCCAGCAGCTATTATTGGAAATATGTTCGCAATTGTAAGTGCAGGGTATATGAAGCGT
TTAGGTGAGAAGAAACCGGAGCTTAGTGGTAACGGTGTATTAGTGAAAACAGACAATCAAGCAGAATTATTAAAAGAACA
AAATACAGAGAAGCCAATTGACTTCTCATTAATGGGAGCAGGTTTATTAATTGCGTGTACGTTCTTCATCTTCGGAGGAT
TTGCTTCTAAGTTCATCGGTATTCCTGGGGCAATCATTATGATTTTTTCAGCAGCACTTGTGAAATACTTTAAATTAATG
CCAGCAAAAATGGAGCAAGGAGCATTCCATTTATATAAATTTATTTCGAAGAATTTAACTTGGCCTTTAATGGTTGGATT
AGGATTGCTATATATTCCGTTAAAAGACGTAGCAGCAGTTCTTTCAGTAGGATATGTTGTTGTGTGCGCATCGGTTGTTC
TTACAATGGTAGCATCAGGTTTTATTGTAGGGAAAGTGATGAAGATGTATCCAGTTGAATCGGCGATTGTAACTGGATGT
CATAGCGGTTTAGGTGGAACTGGAGATGTTGCTATTTTATCAGCTTCAAATCGTATGGAATTAATGCCGTTCGCGCAAAT
TTCTACTCGTTTAGGCGGAGCCGCAATGGTTGTAACAGCGACAATATTATTAAAAATGTTTTCATGA

Upstream 100 bases:

>100_bases
TACTTTTTTTAATTACAAAATCAATTACAAAACTTACAAAAACTATTTTTACTATTGAAAGCGTTTTAATATTGTTATTA
AGAAAACGAGGGGGTGCCAT

Downstream 100 bases:

>100_bases
TCAAACAAGCTAGCTATATTCATATAGCTAGCTTGTCAAATTAAGGGGAGATTATAAGTATGTTAGCAAATCAAATTAAT
GAAAGATCATTGTTATTGCA

Product: citrate cation symporter family

Products: NA

Alternate protein names: Sodium-dependent malate transporter [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MGIQKNVEAVSFSEGNEVQRESFASKIMNVKIGVIPLPLYVVLAAIIYGASVYNKLPADMIGGFAVIMIMGIFLGDIGMR
IPILKNIGGPAILSLFIPSLLVFFNWMNPASMEAATMLMKKSNFLYLYISCLVVGSILGMNRKVLVQGFVRMFIPLVVGT
LASVAVGLLVGSLFGFEMKHTFFFIIVPIVSGGIGEGILPLSLAYSDILNESSATFVSQLIPAAIIGNMFAIVSAGYMKR
LGEKKPELSGNGVLVKTDNQAELLKEQNTEKPIDFSLMGAGLLIACTFFIFGGFASKFIGIPGAIIMIFSAALVKYFKLM
PAKMEQGAFHLYKFISKNLTWPLMVGLGLLYIPLKDVAAVLSVGYVVVCASVVLTMVASGFIVGKVMKMYPVESAIVTGC
HSGLGGTGDVAILSASNRMELMPFAQISTRLGGAAMVVTATILLKMFS

Sequences:

>Translated_448_residues
MGIQKNVEAVSFSEGNEVQRESFASKIMNVKIGVIPLPLYVVLAAIIYGASVYNKLPADMIGGFAVIMIMGIFLGDIGMR
IPILKNIGGPAILSLFIPSLLVFFNWMNPASMEAATMLMKKSNFLYLYISCLVVGSILGMNRKVLVQGFVRMFIPLVVGT
LASVAVGLLVGSLFGFEMKHTFFFIIVPIVSGGIGEGILPLSLAYSDILNESSATFVSQLIPAAIIGNMFAIVSAGYMKR
LGEKKPELSGNGVLVKTDNQAELLKEQNTEKPIDFSLMGAGLLIACTFFIFGGFASKFIGIPGAIIMIFSAALVKYFKLM
PAKMEQGAFHLYKFISKNLTWPLMVGLGLLYIPLKDVAAVLSVGYVVVCASVVLTMVASGFIVGKVMKMYPVESAIVTGC
HSGLGGTGDVAILSASNRMELMPFAQISTRLGGAAMVVTATILLKMFS
>Mature_447_residues
GIQKNVEAVSFSEGNEVQRESFASKIMNVKIGVIPLPLYVVLAAIIYGASVYNKLPADMIGGFAVIMIMGIFLGDIGMRI
PILKNIGGPAILSLFIPSLLVFFNWMNPASMEAATMLMKKSNFLYLYISCLVVGSILGMNRKVLVQGFVRMFIPLVVGTL
ASVAVGLLVGSLFGFEMKHTFFFIIVPIVSGGIGEGILPLSLAYSDILNESSATFVSQLIPAAIIGNMFAIVSAGYMKRL
GEKKPELSGNGVLVKTDNQAELLKEQNTEKPIDFSLMGAGLLIACTFFIFGGFASKFIGIPGAIIMIFSAALVKYFKLMP
AKMEQGAFHLYKFISKNLTWPLMVGLGLLYIPLKDVAAVLSVGYVVVCASVVLTMVASGFIVGKVMKMYPVESAIVTGCH
SGLGGTGDVAILSASNRMELMPFAQISTRLGGAAMVVTATILLKMFS

Specific function: Acts as a Na(+)-malate symporter, as it catalyzes malate-dependent uptake of Na(+) and Na(+)-dependent uptake of malate [H]

COG id: COG3493

COG function: function code C; Na+/citrate symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:citrate (SCF) symporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004679
- InterPro:   IPR018025 [H]

Pfam domain/function: PF03390 2HCT [H]

EC number: NA

Molecular weight: Translated: 47880; Mature: 47749

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIQKNVEAVSFSEGNEVQRESFASKIMNVKIGVIPLPLYVVLAAIIYGASVYNKLPADM
CCCCCCCCEEECCCCCHHHHHHHHHHHHHCEECEEHHHHHHHHHHHHHHHHHHHCCCHHH
IGGFAVIMIMGIFLGDIGMRIPILKNIGGPAILSLFIPSLLVFFNWMNPASMEAATMLMK
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KSNFLYLYISCLVVGSILGMNRKVLVQGFVRMFIPLVVGTLASVAVGLLVGSLFGFEMKH
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFFFIIVPIVSGGIGEGILPLSLAYSDILNESSATFVSQLIPAAIIGNMFAIVSAGYMKR
HHHHEEHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEKKPELSGNGVLVKTDNQAELLKEQNTEKPIDFSLMGAGLLIACTFFIFGGFASKFIG
HCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IPGAIIMIFSAALVKYFKLMPAKMEQGAFHLYKFISKNLTWPLMVGLGLLYIPLKDVAAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LSVGYVVVCASVVLTMVASGFIVGKVMKMYPVESAIVTGCHSGLGGTGDVAILSASNRME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEEEECCCCCE
LMPFAQISTRLGGAAMVVTATILLKMFS
ECHHHHHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GIQKNVEAVSFSEGNEVQRESFASKIMNVKIGVIPLPLYVVLAAIIYGASVYNKLPADM
CCCCCCCEEECCCCCHHHHHHHHHHHHHCEECEEHHHHHHHHHHHHHHHHHHHCCCHHH
IGGFAVIMIMGIFLGDIGMRIPILKNIGGPAILSLFIPSLLVFFNWMNPASMEAATMLMK
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
KSNFLYLYISCLVVGSILGMNRKVLVQGFVRMFIPLVVGTLASVAVGLLVGSLFGFEMKH
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TFFFIIVPIVSGGIGEGILPLSLAYSDILNESSATFVSQLIPAAIIGNMFAIVSAGYMKR
HHHHEEHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGEKKPELSGNGVLVKTDNQAELLKEQNTEKPIDFSLMGAGLLIACTFFIFGGFASKFIG
HCCCCCCCCCCEEEEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
IPGAIIMIFSAALVKYFKLMPAKMEQGAFHLYKFISKNLTWPLMVGLGLLYIPLKDVAAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LSVGYVVVCASVVLTMVASGFIVGKVMKMYPVESAIVTGCHSGLGGTGDVAILSASNRME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCEEEEECCCCCE
LMPFAQISTRLGGAAMVVTATILLKMFS
ECHHHHHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10903309; 12949159 [H]