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The map label for this gene is fabD [H]

Identifier: 21674924

GI number: 21674924

Start: 2001579

End: 2002496

Strand: Direct

Name: fabD [H]

Synonym: CT2115

Alternate gene names: 21674924

Gene position: 2001579-2002496 (Clockwise)

Preceding gene: 21674923

Following gene: 21674925

Centisome position: 92.88

GC content: 61.11

Gene sequence:

>918_bases
ATGAAAGCATTTGTTTTCCCCGGTCAGGGTTCGCAGTACTGCGGCATGGGCCGCGATCTGTACGAGCGCTTCCCGGAAGC
GCAGGAGCTCATGGACAAGGCCGACTCAATTCTCGGATTCTCGATCACCAATATCATGTTCAACGGCAGCGAGGATGAGC
TGAAACAGACACGCTATACCCAGCTCGCTATCTTCCTGCACAGCTTCGCGGCGGCCACCCTTCTCGGACGTGAGGGCGTT
AAGATGGCAGCGGGCCACAGCCTTGGCGAATACACGGCGCTCTGCTTCTCGGGTGCGATTTCGTTCGAGGATGCGGTGAG
GCTCGTGGCCAAGCGCGGCGAACTGATGCAGAACGCCGGACAGCAGAATCCCGGCACGATGGCCGCGATCATCGGCATGG
CCGACGACGCGCTCGACGCGCTCCTGGAAGAGGCGAGTGCAAGCGGCATCGTGCAGGCGGCAAACTTCAACTCGCCCGGC
CAGATTGTCATCTCCGGCGACGTCGATGCAGTACGCAAGGCGGTCGAACTCGCGTCGTCGAAAGGCGCGCGCATGGCCAA
GGAGCTGGTCGTCTCAGGCGCTTTCCACTCGCCGCTGATGAAACCCGCCGAAAAGGAGTTTGCCGAAACGCTCGACACCA
TCGCGATCCGCGACGCCGAAATTCCGGTCTGCATGAACGTGGTCGCCAAACCGGTCACGGCGGCAACGGAAATCCGCGCG
AACCTCATCAGCCAGCTCACCAGCTCGGTGCTCTGGAGCCAGTCGGTGCAGGCGATGGTGGACGCGGGCATCACCGAATT
TGTCGAGGTCGGCCCCCAGAAAGTGCTGCAGGGCCTCATTAAAAGAATCAGCAAATCCACTATGTGCTCGGGAGTCGATA
CCGCCGATCAGGTGGATGCGATGCGCACTCCGGCCTAA

Upstream 100 bases:

>100_bases
GGCTCGAACCTCGTGCTGGTGAGCTTCGGAGCAGGCTACACCTGGGGCGGCGTTTACGTCCGCTGGCAGTAAGCCAAACC
ATTCAAAGGAATTACAGGAT

Downstream 100 bases:

>100_bases
CCATAGAAAAACGCAAAGAAACGATTATGACCATGTTCACAGGAAAAACCGCCGTCGTCACCGGCGCGGCACGAGGCATC
GGCCAGTCGATCGCCCTCGA

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKAFVFPGQGSQYCGMGRDLYERFPEAQELMDKADSILGFSITNIMFNGSEDELKQTRYTQLAIFLHSFAAATLLGREGV
KMAAGHSLGEYTALCFSGAISFEDAVRLVAKRGELMQNAGQQNPGTMAAIIGMADDALDALLEEASASGIVQAANFNSPG
QIVISGDVDAVRKAVELASSKGARMAKELVVSGAFHSPLMKPAEKEFAETLDTIAIRDAEIPVCMNVVAKPVTAATEIRA
NLISQLTSSVLWSQSVQAMVDAGITEFVEVGPQKVLQGLIKRISKSTMCSGVDTADQVDAMRTPA

Sequences:

>Translated_305_residues
MKAFVFPGQGSQYCGMGRDLYERFPEAQELMDKADSILGFSITNIMFNGSEDELKQTRYTQLAIFLHSFAAATLLGREGV
KMAAGHSLGEYTALCFSGAISFEDAVRLVAKRGELMQNAGQQNPGTMAAIIGMADDALDALLEEASASGIVQAANFNSPG
QIVISGDVDAVRKAVELASSKGARMAKELVVSGAFHSPLMKPAEKEFAETLDTIAIRDAEIPVCMNVVAKPVTAATEIRA
NLISQLTSSVLWSQSVQAMVDAGITEFVEVGPQKVLQGLIKRISKSTMCSGVDTADQVDAMRTPA
>Mature_305_residues
MKAFVFPGQGSQYCGMGRDLYERFPEAQELMDKADSILGFSITNIMFNGSEDELKQTRYTQLAIFLHSFAAATLLGREGV
KMAAGHSLGEYTALCFSGAISFEDAVRLVAKRGELMQNAGQQNPGTMAAIIGMADDALDALLEEASASGIVQAANFNSPG
QIVISGDVDAVRKAVELASSKGARMAKELVVSGAFHSPLMKPAEKEFAETLDTIAIRDAEIPVCMNVVAKPVTAATEIRA
NLISQLTSSVLWSQSVQAMVDAGITEFVEVGPQKVLQGLIKRISKSTMCSGVDTADQVDAMRTPA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=296, Percent_Identity=32.4324324324324, Blast_Score=144, Evalue=8e-35,
Organism=Homo sapiens, GI27477045, Length=107, Percent_Identity=39.2523364485981, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI41872631, Length=293, Percent_Identity=26.2798634812287, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1787334, Length=294, Percent_Identity=42.1768707482993, Blast_Score=201, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI71984332, Length=286, Percent_Identity=28.3216783216783, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=294, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24665753, Length=299, Percent_Identity=34.4481605351171, Blast_Score=159, Evalue=3e-39,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 32452; Mature: 32452

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFVFPGQGSQYCGMGRDLYERFPEAQELMDKADSILGFSITNIMFNGSEDELKQTRYT
CCEEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHH
QLAIFLHSFAAATLLGREGVKMAAGHSLGEYTALCFSGAISFEDAVRLVAKRGELMQNAG
HHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
QQNPGTMAAIIGMADDALDALLEEASASGIVQAANFNSPGQIVISGDVDAVRKAVELASS
CCCCCHHHHHHHCCHHHHHHHHHHHHHCCEEEECCCCCCCCEEEECCHHHHHHHHHHHHC
KGARMAKELVVSGAFHSPLMKPAEKEFAETLDTIAIRDAEIPVCMNVVAKPVTAATEIRA
CCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
NLISQLTSSVLWSQSVQAMVDAGITEFVEVGPQKVLQGLIKRISKSTMCSGVDTADQVDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MRTPA
HCCCC
>Mature Secondary Structure
MKAFVFPGQGSQYCGMGRDLYERFPEAQELMDKADSILGFSITNIMFNGSEDELKQTRYT
CCEEEECCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHH
QLAIFLHSFAAATLLGREGVKMAAGHSLGEYTALCFSGAISFEDAVRLVAKRGELMQNAG
HHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCC
QQNPGTMAAIIGMADDALDALLEEASASGIVQAANFNSPGQIVISGDVDAVRKAVELASS
CCCCCHHHHHHHCCHHHHHHHHHHHHHCCEEEECCCCCCCCEEEECCHHHHHHHHHHHHC
KGARMAKELVVSGAFHSPLMKPAEKEFAETLDTIAIRDAEIPVCMNVVAKPVTAATEIRA
CCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
NLISQLTSSVLWSQSVQAMVDAGITEFVEVGPQKVLQGLIKRISKSTMCSGVDTADQVDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
MRTPA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]