Click here to switch to the map view.

The map label for this gene is ftsK

Identifier: 21674601

GI number: 21674601

Start: 1692210

End: 1694624

Strand: Reverse

Name: ftsK

Synonym: CT1787

Alternate gene names: 21674601

Gene position: 1694624-1692210 (Counterclockwise)

Preceding gene: 21674602

Following gene: 21674597

Centisome position: 78.64

GC content: 58.76

Gene sequence:

>2415_bases
ATGCTCGCCGCGCTCTTCAGCATTGCCGCGGTGTTCGGTTTTCATGCCGAGGACGAACCGTACATTGTGACGTTGCCCTG
GTATGAGCTTTTCTCCAGCGCGGCCAAGGCGGTTGCCGGAACGATTCACAACCCCTTCGGCCTGTTTGGCGCGAGGGTGT
CGGTCTTTTTTATTCGTGTTTTACTTGGCTATCCATCGGTGATGCCTCTTTTTGGTTTCCTTGTGCTCGGATGGCATCTG
TTCCGGGCGAAACCTCTCGGACCCGGGCTGTTTTTCCTTGTGTACACCCTCCTGATGGCGCTCGATTTGTCAGCCATGTT
CGGTCTTTCGATGTTGCCTCTGGCCGATCTCATGTCCGGAGCGACTGGCCGGATGATGGCTTCGTTCCTCTCTACCGTCA
TCGGCTATCCCGGGGCGTGGGCGCTGACCGCCATTATCGCTGCGGTGCTGACCTTCTATATGGGTCGGGATTTTATTGTG
GATACGATTGCCGGCGTGAGTGGCTTTTTCGGAAAACTGTTGGCAACCGTGCAGGCGATCAGGGCCGAACGCCACAGAAA
GCGCCGGGAAAAGGAGGAGATGCGGGTACGGAAAAAGGCGGAGCGGATGGCAGCCGTCCTTGAAAAGGAGCAGAGAAAGA
GGGACAAGAAAGCACAACGCGCAAGGAAAGCTGGCGACGCTTCAAAGCAAAAGGCGGCTCCATTCGAAAATTCGCCAGAG
ACTCCAGCTCCTGTGATGGATGTGGAGCCCGCGCCGCCACTGCTCAATCCGGCCGTGTCCGAACCTGTCGTTATTCCTGC
GGAGGTCGAGGAGATTCGCACGCCGGAACCGGCTCCCGTCAGGCCGGAAGAGGGGCCGGAGATGATCATCAAGCCGGGGG
TGCAGGAGGCGGAGGCCGATCTGGACGAACGGGCGCTCAAGGTCAGGACGCATGACCATGTCAAGTATCGCTTTCCGTCG
ATTGACCTGTTGCGGCGTCCCAAGGACGAGGACGAAAGCTACGACGAGCGCCACCTGGCCGAAACCAAGGATCGCCTGCT
TGAAAAGCTCAGGATTTACAAAATCGACGTCATTCGTATCGCCACCACCGTTGGCCCGCGAGTGGCGCTTTTCGAGCTCG
AACTTGCGCCGGAGGTGAAGATCAGCCGGATCAAGTCGCTCGAAAACGATCTCGCCATGGCGATGGCCTCCTCGTCCGGC
GGCATCAGGATCATTGCTCCCATTCCCGGCAAGAACGCCATTGGCGTCGAAATACCGATCAGCAAGCCGCGGCCGGTGGT
GATGCGCTCGGTGCTTCAGGTCGAAAAGTTCAAGAACAATTCGATGGCTCTGCCAATCGTCCTCGGCAAGAGCATCTCGA
ACGAAGTGATCGTCGATGACCTGGCCGCCATGCCGCACCTCCTCATTGCGGGCGCGACCGGTGCGGGCAAGTCGGTGGCG
ATCAATGTACTGCTCACGAGTCTGCTTTATTCGAAGAAACCGGACGAGGTCAAATTCGTGCTGATCGATCCGAAGCGGGT
CGAGCTCAAGCCGTACAAGCTTCTGAAAGACCATTTCCTGCCGAAAATTCCCGGCATGGAGGAGCAGATCATCGTCACCG
ATCCACAGAAAGCGGTGTCCGCGCTCAGGTCGGTGGTCAGGGAGATGGAGCACCGGTACGAGCTGCTCGAACAGTGCGGC
GTGCGCAACATCGGCGAGTACAACCGGAAGATGAAAGACGAGGCGATGTTCTACCTGGTCGTCGTTGTTGACGAGCTTGC
CGACCTGATGATCACGGCAGGTCGCGAGGTCGAGGAGCCTATCACGAGGCTCGCGCAGATGGCCAGGGCGGTCGGCATTC
ACCTGATCGTGGCTACGCAGCGCCCGTCGGTTGATATCATCACCGGTATCATCAAGGCCAACTTCCCCTCGCGCATCGCT
TTCCAGGTGGCCAGCAAGGTCGATTCCCGCACCATTCTTGACGTGTCTGGCGCAGAGCAGTTGCTTGGCAGTGGCGACAT
GCTGTTCCAGTCGGCAAAGATGTCCAAACCGCAACGGATACAGTGCCCCTATATTTCCCTCTCAGAAGTCGATGCGATAA
CAGAGTTTATTGGCCAGCAGCCGCCGCTTCGAGCCGAGTGTATGCTGCCAGAGCCGCCATCGTCCAGCGGCAATGGCTCC
TCATCGGGATTTGATCAGGACAGGGGCCGGCGCGACAGCATGTTCGAGGAGGCAGCCAGGCTCGTCGTCATGCACCAGCA
GGCCAGCGTCTCCCTTCTGCAGCGCCGCTTGCGGCTGGGTTTCAGCCGCGCGGGACGGGTGATGGATCAGCTCGAACAGA
GCGGTATCGTCAGCGCCGGCGACGGCAGCAAGCCAAGAGAGGTGCTTGTCAAGAACGAAGACTCGCTTGAGCTGCTGCTG
AGAAATCTGGATTGA

Upstream 100 bases:

>100_bases
ATGAACTGATCACAAGCCGGTCTCCCCCTTGAAAAACAAGATCAACATAAAGGCTTTCTGCACGGATAGTCTCGTCACTG
AAGTTGCTGGTATCGCCTTG

Downstream 100 bases:

>100_bases
AAATCCGGGTGTGTTTTTTGTCCTTATAGGTCAGAAACGAAAACGGCTGCCTCGGTAACTTCCGGGCAGCCGTTTCGCAT
TGCTGTGCTCTTCAGCCGGT

Product: FtsK/SpoIIIE family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 804; Mature: 804

Protein sequence:

>804_residues
MLAALFSIAAVFGFHAEDEPYIVTLPWYELFSSAAKAVAGTIHNPFGLFGARVSVFFIRVLLGYPSVMPLFGFLVLGWHL
FRAKPLGPGLFFLVYTLLMALDLSAMFGLSMLPLADLMSGATGRMMASFLSTVIGYPGAWALTAIIAAVLTFYMGRDFIV
DTIAGVSGFFGKLLATVQAIRAERHRKRREKEEMRVRKKAERMAAVLEKEQRKRDKKAQRARKAGDASKQKAAPFENSPE
TPAPVMDVEPAPPLLNPAVSEPVVIPAEVEEIRTPEPAPVRPEEGPEMIIKPGVQEAEADLDERALKVRTHDHVKYRFPS
IDLLRRPKDEDESYDERHLAETKDRLLEKLRIYKIDVIRIATTVGPRVALFELELAPEVKISRIKSLENDLAMAMASSSG
GIRIIAPIPGKNAIGVEIPISKPRPVVMRSVLQVEKFKNNSMALPIVLGKSISNEVIVDDLAAMPHLLIAGATGAGKSVA
INVLLTSLLYSKKPDEVKFVLIDPKRVELKPYKLLKDHFLPKIPGMEEQIIVTDPQKAVSALRSVVREMEHRYELLEQCG
VRNIGEYNRKMKDEAMFYLVVVVDELADLMITAGREVEEPITRLAQMARAVGIHLIVATQRPSVDIITGIIKANFPSRIA
FQVASKVDSRTILDVSGAEQLLGSGDMLFQSAKMSKPQRIQCPYISLSEVDAITEFIGQQPPLRAECMLPEPPSSSGNGS
SSGFDQDRGRRDSMFEEAARLVVMHQQASVSLLQRRLRLGFSRAGRVMDQLEQSGIVSAGDGSKPREVLVKNEDSLELLL
RNLD

Sequences:

>Translated_804_residues
MLAALFSIAAVFGFHAEDEPYIVTLPWYELFSSAAKAVAGTIHNPFGLFGARVSVFFIRVLLGYPSVMPLFGFLVLGWHL
FRAKPLGPGLFFLVYTLLMALDLSAMFGLSMLPLADLMSGATGRMMASFLSTVIGYPGAWALTAIIAAVLTFYMGRDFIV
DTIAGVSGFFGKLLATVQAIRAERHRKRREKEEMRVRKKAERMAAVLEKEQRKRDKKAQRARKAGDASKQKAAPFENSPE
TPAPVMDVEPAPPLLNPAVSEPVVIPAEVEEIRTPEPAPVRPEEGPEMIIKPGVQEAEADLDERALKVRTHDHVKYRFPS
IDLLRRPKDEDESYDERHLAETKDRLLEKLRIYKIDVIRIATTVGPRVALFELELAPEVKISRIKSLENDLAMAMASSSG
GIRIIAPIPGKNAIGVEIPISKPRPVVMRSVLQVEKFKNNSMALPIVLGKSISNEVIVDDLAAMPHLLIAGATGAGKSVA
INVLLTSLLYSKKPDEVKFVLIDPKRVELKPYKLLKDHFLPKIPGMEEQIIVTDPQKAVSALRSVVREMEHRYELLEQCG
VRNIGEYNRKMKDEAMFYLVVVVDELADLMITAGREVEEPITRLAQMARAVGIHLIVATQRPSVDIITGIIKANFPSRIA
FQVASKVDSRTILDVSGAEQLLGSGDMLFQSAKMSKPQRIQCPYISLSEVDAITEFIGQQPPLRAECMLPEPPSSSGNGS
SSGFDQDRGRRDSMFEEAARLVVMHQQASVSLLQRRLRLGFSRAGRVMDQLEQSGIVSAGDGSKPREVLVKNEDSLELLL
RNLD
>Mature_804_residues
MLAALFSIAAVFGFHAEDEPYIVTLPWYELFSSAAKAVAGTIHNPFGLFGARVSVFFIRVLLGYPSVMPLFGFLVLGWHL
FRAKPLGPGLFFLVYTLLMALDLSAMFGLSMLPLADLMSGATGRMMASFLSTVIGYPGAWALTAIIAAVLTFYMGRDFIV
DTIAGVSGFFGKLLATVQAIRAERHRKRREKEEMRVRKKAERMAAVLEKEQRKRDKKAQRARKAGDASKQKAAPFENSPE
TPAPVMDVEPAPPLLNPAVSEPVVIPAEVEEIRTPEPAPVRPEEGPEMIIKPGVQEAEADLDERALKVRTHDHVKYRFPS
IDLLRRPKDEDESYDERHLAETKDRLLEKLRIYKIDVIRIATTVGPRVALFELELAPEVKISRIKSLENDLAMAMASSSG
GIRIIAPIPGKNAIGVEIPISKPRPVVMRSVLQVEKFKNNSMALPIVLGKSISNEVIVDDLAAMPHLLIAGATGAGKSVA
INVLLTSLLYSKKPDEVKFVLIDPKRVELKPYKLLKDHFLPKIPGMEEQIIVTDPQKAVSALRSVVREMEHRYELLEQCG
VRNIGEYNRKMKDEAMFYLVVVVDELADLMITAGREVEEPITRLAQMARAVGIHLIVATQRPSVDIITGIIKANFPSRIA
FQVASKVDSRTILDVSGAEQLLGSGDMLFQSAKMSKPQRIQCPYISLSEVDAITEFIGQQPPLRAECMLPEPPSSSGNGS
SSGFDQDRGRRDSMFEEAARLVVMHQQASVSLLQRRLRLGFSRAGRVMDQLEQSGIVSAGDGSKPREVLVKNEDSLELLL
RNLD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain

Homologues:

Organism=Escherichia coli, GI1787117, Length=500, Percent_Identity=42.4, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSK_CHLTE (Q8KBK0)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662666.1
- ProteinModelPortal:   Q8KBK0
- SMR:   Q8KBK0
- GeneID:   1008231
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1787
- NMPDR:   fig|194439.1.peg.1760
- TIGR:   CT1787
- HOGENOM:   HBG662140
- OMA:   QVEKFKN
- ProtClustDB:   CLSK637935
- BioCyc:   CTEP194439:CT_1787-MONOMER
- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543
- SMART:   SM00382
- SMART:   SM00843

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE

EC number: NA

Molecular weight: Translated: 88911; Mature: 88911

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xec80610)-; HASH(0xf609c80)-; HASH(0xf607490)-; HASH(0xe873d98)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAALFSIAAVFGFHAEDEPYIVTLPWYELFSSAAKAVAGTIHNPFGLFGARVSVFFIRV
CHHHHHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LLGYPSVMPLFGFLVLGWHLFRAKPLGPGLFFLVYTLLMALDLSAMFGLSMLPLADLMSG
HHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
ATGRMMASFLSTVIGYPGAWALTAIIAAVLTFYMGRDFIVDTIAGVSGFFGKLLATVQAI
CHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
RAERHRKRREKEEMRVRKKAERMAAVLEKEQRKRDKKAQRARKAGDASKQKAAPFENSPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCC
TPAPVMDVEPAPPLLNPAVSEPVVIPAEVEEIRTPEPAPVRPEEGPEMIIKPGVQEAEAD
CCCCCCCCCCCCCCCCCCCCCCEECCCCHHHCCCCCCCCCCCCCCCCEEECCCCCHHHCC
LDERALKVRTHDHVKYRFPSIDLLRRPKDEDESYDERHLAETKDRLLEKLRIYKIDVIRI
HHHHHHHHCCCCCEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEE
ATTVGPRVALFELELAPEVKISRIKSLENDLAMAMASSSGGIRIIAPIPGKNAIGVEIPI
EHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEECC
SKPRPVVMRSVLQVEKFKNNSMALPIVLGKSISNEVIVDDLAAMPHLLIAGATGAGKSVA
CCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCCHHH
INVLLTSLLYSKKPDEVKFVLIDPKRVELKPYKLLKDHFLPKIPGMEEQIIVTDPQKAVS
HHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCEEEEECHHHHHH
ALRSVVREMEHRYELLEQCGVRNIGEYNRKMKDEAMFYLVVVVDELADLMITAGREVEEP
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ITRLAQMARAVGIHLIVATQRPSVDIITGIIKANFPSRIAFQVASKVDSRTILDVSGAEQ
HHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCHHH
LLGSGDMLFQSAKMSKPQRIQCPYISLSEVDAITEFIGQQPPLRAECMLPEPPSSSGNGS
HHCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCC
SSGFDQDRGRRDSMFEEAARLVVMHQQASVSLLQRRLRLGFSRAGRVMDQLEQSGIVSAG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCEECC
DGSKPREVLVKNEDSLELLLRNLD
CCCCCHHEEECCCCHHHHHHHHCH
>Mature Secondary Structure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CCCCCHHEEECCCCHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901