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The map label for this gene is ruvB

Identifier: 21674448

GI number: 21674448

Start: 1539764

End: 1540798

Strand: Reverse

Name: ruvB

Synonym: CT1630

Alternate gene names: 21674448

Gene position: 1540798-1539764 (Counterclockwise)

Preceding gene: 21674449

Following gene: 21674447

Centisome position: 71.5

GC content: 61.45

Gene sequence:

>1035_bases
GTGAGGATTGAAGCCCTGAATACCGCACCCGACGCGACGGAAGCCCGGTTCGAGGAGCAGATACGGCCGCAAAAGATGGG
CGATTTTGCCGGGCAAAAAAAGCTGATCGACAACCTCAAAGTGTTCATCACTGCGGCGCGTAAACGCGGTGAAGCGCTCG
ACCACGTGTTGCTTTCCGGTCCGCCCGGACTCGGCAAGACCACGCTTGCACACATCATCGCCGCCGAGATGGGTGGGAGT
ATCAAGATCACCTCCGGGCCGCTGATCGACAAGGCGGGCAACCTGGCCGGCCTGTTGACCAGCATGAAAAAGGGGGACAT
CCTCTTTATCGACGAAATCCACCGACTCGCTCCGGCGGTCGAGGAGTACCTCTACTCGGCAATGGAGGATTACCGCATCG
ACATCCTGCTCGACAGCGGCCCGGCGTCGCGAGCCGTGCAGCTCAAACTCGAACCCTTCACGCTGGTTGGCGCCACCACG
CGGGCTGGCCTTTTGACTTCGCCGCTGCGCGCGCGCTTCGGCATCAACAGCCGTCTCGACTACTACAACCCCGAACTCCT
GCAAAGCATCATTATTCGGGCGGCAGGTATTCTGAACATCGGCATTGACGAGGACGCGGCGATGGAAATTGCCCGCCGCT
CGCGTGGCACCCCGCGCATCGCCAACCGCCTGTTGCGGCGGGCGCGCGACTTCGCGCAGGTGGCAGGCGACGCCTCGATT
TCGCTCGCCGTCGCTCGTCGCACCCTCGAATCGCTCGAAATCGACGAAGGCGGCCTTGACGACATGGACAAGAAAATCCT
CGAAGCGATCGTCCGCAAGTTCAACGGCGGTCCGGTTGGTTTGGCCTCGCTGGCTGTGTCGGTCGGTGAGGAGCAGGACA
CTATCGAGGAGGTCTACGAACCCTATCTGATCCAGATGGGGTACCTCTCCCGAACGCCTCGTGGGCGTGTTGCTACCCGC
CTTGCCATGAGCCGGTTTGCTCATCCAGGCATCTCCAGCCAGGGGTCGCTGTTTGACACTGCCGAAGATGGGTAA

Upstream 100 bases:

>100_bases
GTCTCCGGCACGATGATCGTCTTCGGTAACCTCTTGGCCGACGTGCTCTACGCGGTGGTCGATCCGAGGATCAAACTGTG
AATGCAAAACGAGAGCTTGA

Downstream 100 bases:

>100_bases
GGCGTGTCGAATTGGCGCTTTCCGATGGCTCCTCTCGCTGCTGGCGCTCCTCGCTGGCGTGGTGCTGTCAGCTTTCCCGG
CAATGGCGTCGGTCAGCGGT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MRIEALNTAPDATEARFEEQIRPQKMGDFAGQKKLIDNLKVFITAARKRGEALDHVLLSGPPGLGKTTLAHIIAAEMGGS
IKITSGPLIDKAGNLAGLLTSMKKGDILFIDEIHRLAPAVEEYLYSAMEDYRIDILLDSGPASRAVQLKLEPFTLVGATT
RAGLLTSPLRARFGINSRLDYYNPELLQSIIIRAAGILNIGIDEDAAMEIARRSRGTPRIANRLLRRARDFAQVAGDASI
SLAVARRTLESLEIDEGGLDDMDKKILEAIVRKFNGGPVGLASLAVSVGEEQDTIEEVYEPYLIQMGYLSRTPRGRVATR
LAMSRFAHPGISSQGSLFDTAEDG

Sequences:

>Translated_344_residues
MRIEALNTAPDATEARFEEQIRPQKMGDFAGQKKLIDNLKVFITAARKRGEALDHVLLSGPPGLGKTTLAHIIAAEMGGS
IKITSGPLIDKAGNLAGLLTSMKKGDILFIDEIHRLAPAVEEYLYSAMEDYRIDILLDSGPASRAVQLKLEPFTLVGATT
RAGLLTSPLRARFGINSRLDYYNPELLQSIIIRAAGILNIGIDEDAAMEIARRSRGTPRIANRLLRRARDFAQVAGDASI
SLAVARRTLESLEIDEGGLDDMDKKILEAIVRKFNGGPVGLASLAVSVGEEQDTIEEVYEPYLIQMGYLSRTPRGRVATR
LAMSRFAHPGISSQGSLFDTAEDG
>Mature_344_residues
MRIEALNTAPDATEARFEEQIRPQKMGDFAGQKKLIDNLKVFITAARKRGEALDHVLLSGPPGLGKTTLAHIIAAEMGGS
IKITSGPLIDKAGNLAGLLTSMKKGDILFIDEIHRLAPAVEEYLYSAMEDYRIDILLDSGPASRAVQLKLEPFTLVGATT
RAGLLTSPLRARFGINSRLDYYNPELLQSIIIRAAGILNIGIDEDAAMEIARRSRGTPRIANRLLRRARDFAQVAGDASI
SLAVARRTLESLEIDEGGLDDMDKKILEAIVRKFNGGPVGLASLAVSVGEEQDTIEEVYEPYLIQMGYLSRTPRGRVATR
LAMSRFAHPGISSQGSLFDTAEDG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=324, Percent_Identity=54.9382716049383, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_CHLTE (Q8KC00)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662513.1
- ProteinModelPortal:   Q8KC00
- SMR:   Q8KC00
- GeneID:   1006118
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1630
- NMPDR:   fig|194439.1.peg.1607
- TIGR:   CT1630
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   CTEP194439:CT_1630-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37371; Mature: 37371

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIEALNTAPDATEARFEEQIRPQKMGDFAGQKKLIDNLKVFITAARKRGEALDHVLLSG
CEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPGLGKTTLAHIIAAEMGGSIKITSGPLIDKAGNLAGLLTSMKKGDILFIDEIHRLAPAV
CCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHH
EEYLYSAMEDYRIDILLDSGPASRAVQLKLEPFTLVGATTRAGLLTSPLRARFGINSRLD
HHHHHHHHHCCEEEEEECCCCCCCEEEEEECCEEEECCCHHCCHHHHHHHHHCCCCCCCC
YYNPELLQSIIIRAAGILNIGIDEDAAMEIARRSRGTPRIANRLLRRARDFAQVAGDASI
CCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHH
SLAVARRTLESLEIDEGGLDDMDKKILEAIVRKFNGGPVGLASLAVSVGEEQDTIEEVYE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHH
PYLIQMGYLSRTPRGRVATRLAMSRFAHPGISSQGSLFDTAEDG
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRIEALNTAPDATEARFEEQIRPQKMGDFAGQKKLIDNLKVFITAARKRGEALDHVLLSG
CEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PPGLGKTTLAHIIAAEMGGSIKITSGPLIDKAGNLAGLLTSMKKGDILFIDEIHRLAPAV
CCCCCHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHH
EEYLYSAMEDYRIDILLDSGPASRAVQLKLEPFTLVGATTRAGLLTSPLRARFGINSRLD
HHHHHHHHHCCEEEEEECCCCCCCEEEEEECCEEEECCCHHCCHHHHHHHHHCCCCCCCC
YYNPELLQSIIIRAAGILNIGIDEDAAMEIARRSRGTPRIANRLLRRARDFAQVAGDASI
CCCHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHH
SLAVARRTLESLEIDEGGLDDMDKKILEAIVRKFNGGPVGLASLAVSVGEEQDTIEEVYE
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCHHHHHHHHH
PYLIQMGYLSRTPRGRVATRLAMSRFAHPGISSQGSLFDTAEDG
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901